Definium Therapeutics, Inc.
DFTX- Exchange
- Nasdaq
- Industry
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 362
- +119 vs. Q1 2026
- Shares held
- 114.8M
- +40.3M (+54.1%) vs. Q1 2026
- Total value
- $5.35B
- +$3.94B (+280.1%) vs. Q1 2026
- New holders
- 148
- 117 more added
- Sold out
- 29
- 64 more reduced
5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 362 | $5.35B |
| Q1 2026 | 248 | $1.47B |
| Q4 2025 | 209 | $908.7M |
| Q3 2025 | 196 | $468.6M |
| Q2 2025 | 183 | $271.0M |
| Q1 2025 | 191 | $240.5M |
| Q4 2024 | 174 | $288.9M |
| Q3 2024 | 158 | $281.6M |
| Q2 2024 | 152 | $299.3M |
| Q1 2024 | 135 | $327.2M |
| Q4 2023 | 104 | $17.9M |
| Q3 2023 | 93 | $12.1M |
| Q2 2023 | 84 | $13.9M |
| Q1 2023 | 89 | $12.6M |
| Q4 2022 | 104 | $11.1M |
| Q3 2022 | 101 | $20.5M |
| Q2 2022 | 156 | $15.1M |
| Q1 2022 | 159 | $53.6M |
| Q4 2021 | 176 | $72.0M |
| Q3 2021 | 175 | $104.8M |
| Q2 2021 | 156 | $131.0M |
| Q1 2021 | 8 | $932.0K |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 100,063 | $4.71M | 0.00% | +2,871+3.0% | Added |
| Burkehill Global Management, LP | 100,000 | $4.70M | 0.17% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 96,510 | $4.54M | 0.00% | +73,154+313.2% | Added |
| Voya Investment Management LLC | 95,166 | $4.48M | 0.00% | +78,782+480.8% | Added |
| Keystone Investors Pte Ltd | 95,100 | $4.47M | 0.24% | +95,100 | New |
| Invesco Ltd. | 91,338 | $4.30M | 0.00% | +3,217+3.7% | Added |
| Pier Capital, LLC | 88,598 | $4.17M | 0.55% | +88,598 | New |
| LPL Financial LLC | 86,136 | $4.05M | 0.00% | +7,865+10.0% | Added |
| Squadron Capital Management LLC | 85,000 | $4.00M | 1.37% | +85,000 | New |
| XTX Topco Ltd | 84,393 | $3.97M | 0.05% | +84,393 | New |
| Shay Capital LLC | 80,000 | $3.76M | 0.42% | +80,000 | New |
| Logos Global Management LP | 80,000 | $3.76M | 0.16% | +80,000 | New |
| Citigroup Inc | 79,547 | $3.74M | 0.00% | +53,061+200.3% | Added |
| Vanguard Asset Management, Ltd | 78,604 | $3.70M | 0.00% | +24,586+45.5% | Added |
| Sectoral Asset Management Inc | 78,310 | $3.68M | 2.57% | +78,310 | New |
| MetLife Investment Management | 75,859 | $3.57M | 0.02% | +21,598+39.8% | Added |
| Legal & General Group Plc | 74,004 | $3.48M | 0.00% | +14,205+23.8% | Added |
| Quantinno Capital Management LP | 70,682 | $3.32M | 0.00% | +30,724+76.9% | Added |
| Rockefeller Capital Management L.P. | 70,111 | $3.30M | 0.01% | +14,905+27.0% | Added |
| Platinum Investment Management Ltd | 70,000 | $3.29M | 0.81% | 00.0% | Unchanged |
| Group One Trading, L.P. | 63,943 | $3.01M | 0.09% | −23,889−27.2% | Reduced |
| Algert Global LLC | 63,700 | $3.00M | 0.04% | +63,700 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 59,936 | $2.82M | 0.00% | +13,743+29.8% | Added |
| Vanguard Global Advisers, LLC | 56,942 | $2.68M | 0.00% | +8,898+18.5% | Added |
| Peak Financial Advisors LLC | 56,915 | $2.68M | 1.11% | +56,915 | New |
| Y-Intercept (Hong Kong) Ltd | 54,466 | $2.56M | 0.05% | +54,466 | New |
| Cerity Partners LLC | 53,883 | $2.53M | 0.00% | +53,883 | New |
| Blair William & Co | 53,588 | $2.52M | 0.01% | −107−0.2% | Reduced |
| State of Wisconsin Investment Board | 52,549 | $2.47M | 0.00% | +2,129+4.2% | Added |
| Moody Aldrich Partners LLC | 51,025 | $2.40M | 0.43% | +51,025 | New |
| Kestra Private Wealth Services, LLC | 50,588 | $2.38M | 0.03% | 00.0% | Unchanged |
| Barclays PLC | 50,296 | $2.37M | 0.00% | +10,613+26.7% | Added |
| Atom Investors LP | 49,436 | $2.33M | 0.21% | +49,436 | New |
| Nisa Investment Advisors, LLC | 48,369 | $2.28M | 0.01% | −534−1.1% | Reduced |
| Simplex Trading, LLC | 47,651 | $2.24M | 0.06% | +6,495+15.8% | Added |
| New York State Common Retirement Fund | 45,800 | $2.15M | 0.00% | +16,200+54.7% | Added |
| Allstate Corp | 45,639 | $2.15M | 0.02% | +273+0.6% | Added |
| Jennison Associates LLC | 45,375 | $2.13M | 0.00% | +5,418+13.6% | Added |
| Caption Management, LLC | 45,000 | $2.12M | 0.07% | +11,242+33.3% | Added |
| Polymer Capital Management (HK) LTD | 44,100 | $2.07M | 0.21% | +44,100 | New |
| Aquatic Capital Management LLC | 43,124 | $2.03M | 0.07% | +43,124 | New |
| Ghisallo Capital Management LLC | 41,500 | $1.95M | 0.04% | +41,500 | New |
| CenterBook Partners LP | 41,255 | $1.94M | 0.10% | −1,574−3.7% | Reduced |
| Susquehanna International Group, LLP | 40,954 | $1.93M | 0.00% | −40,502−49.7% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 38,386 | $1.81M | 0.01% | +11,025+40.3% | Added |
| Scotia Capital Inc. | 34,722 | $1.64M | 0.01% | −5,826−14.4% | Reduced |
| TD Waterhouse Canada Inc. | 36,694 | $1.59M | 0.00% | +34,892+1,936.3% | Added |
| STRS Ohio | 33,500 | $1.58M | 0.01% | +14,200+73.6% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 32,394 | $1.52M | 0.00% | +11,526+55.2% | Added |
| Kingswood Wealth Advisors, LLC | 31,444 | $1.48M | 0.06% | +4,853+18.3% | Added |
| Bay Rivers Group | 31,208 | $1.47M | 0.50% | +4,862+18.5% | Added |
| Vestmark Advisory Solutions, Inc. | 30,729 | $1.45M | 0.01% | +30,729 | New |
| State of New Jersey Common Pension Fund D | 30,625 | $1.44M | 0.00% | +3,184+11.6% | Added |
| Arizona State Retirement System | 30,411 | $1.43M | 0.01% | +8,357+37.9% | Added |
| Palumbo Wealth Management LLC | 29,287 | $1.38M | 0.29% | −8,679−22.9% | Reduced |
| SEI Investments Co | 28,582 | $1.34M | 0.00% | +465+1.7% | Added |
| Cinctive Capital Management LP | 28,550 | $1.34M | 0.05% | +15,999+127.5% | Added |
| Vanguard Investments Australia, Ltd. | 28,265 | $1.33M | 0.00% | +7,798+38.1% | Added |
| SG Americas Securities, LLC | 28,262 | $1.33M | 0.00% | +17,769+169.3% | Added |
| Mariner, LLC | 27,207 | $1.28M | 0.00% | −7,644−21.9% | Reduced |
| Stableford Capital II LLC | 27,141 | $1.28M | 0.44% | +27,141 | New |
| Janney Montgomery Scott LLC | 26,664 | $1.25M | 0.00% | +26,664 | New |
| KLP Kapitalforvaltning AS | 25,000 | $1.18M | 0.00% | +8,000+47.1% | Added |
| ACT Capital Management, LLC | 25,000 | $1.18M | 0.77% | +25,000 | New |
| Teachers Retirement System of the State of Kentucky | 24,500 | $1.15M | 0.01% | +24,500 | New |
| CI Private Wealth, LLC | 24,391 | $1.15M | 0.00% | +24,391 | New |
| Rathbone Brothers plc | 22,800 | $1.07M | 0.00% | −7,400−24.5% | Reduced |
| Raymond James Financial Inc | 22,401 | $1.05M | 0.00% | −1,312−5.5% | Reduced |
| HighTower Advisors, LLC | 22,313 | $1.05M | 0.00% | +3,754+20.2% | Added |
| IFG Advisory, LLC | 22,043 | $1.04M | 0.04% | +22,043 | New |
| TFB Advisors LLC | 21,523 | $1.01M | 0.45% | +21,523 | New |
| China Universal Asset Management Co., Ltd. | 21,358 | $1.00M | 0.06% | +1,166+5.8% | Added |
| Walleye Capital LLC | 20,643 | $971.0K | 0.00% | −14,842−41.8% | Reduced |
| ProShare Advisors LLC | 20,615 | $969.7K | 0.00% | +1,884+10.1% | Added |
| Concurrent Investment Advisors, LLC | 20,044 | $942.9K | 0.01% | −1,241−5.8% | Reduced |
| Birchview Capital, LP | 20,000 | $940.8K | 0.44% | +20,000 | New |
| Fore Capital, LLC | 20,000 | $940.8K | 1.25% | +20,000 | New |
| Intech Investment Management LLC | 19,969 | $939.3K | 0.01% | −5,021−20.1% | Reduced |
| Walleye Trading LLC | 18,450 | $867.9K | 0.01% | +13,036+240.8% | Added |
| Sequoia Financial Advisors, LLC | 17,258 | $811.8K | 0.00% | +13+0.1% | Added |
| Envestnet Asset Management Inc | 16,626 | $782.1K | 0.00% | +16,626 | New |
| Cary Street Partners Financial LLC | 15,582 | $733.0K | 0.02% | +15,582 | New |
| Prudential Financial Inc | 15,500 | $729.1K | 0.00% | +15,500 | New |
| Diadema Partners LP | 15,451 | $726.8K | 0.26% | +15,451 | New |
| Twelve Points Wealth Management LLC | 14,245 | $670.1K | 0.13% | +2,000+16.3% | Added |
| Pictet Asset Management Holding SA | 14,077 | $662.2K | 0.00% | +782+5.9% | Added |
| Amundi | 14,068 | $661.8K | 0.00% | −68−0.5% | Reduced |
| Cetera Investment Advisers | 14,029 | $659.9K | 0.00% | −17,795−55.9% | Reduced |
| Allianz Asset Management GmbH | 13,800 | $649.2K | 0.00% | +13,800 | New |
| Persistent Asset Partners Ltd | 13,778 | $648.1K | 0.20% | −2,083−13.1% | Reduced |
| Profund Advisors LLC | 13,571 | $638.4K | 0.02% | −625−4.4% | Reduced |
| FORA Capital, LLC | 13,378 | $628.9K | 0.04% | +13,378 | New |
| Private Advisor Group, LLC | 13,336 | $627.3K | 0.00% | +13,336 | New |
| Dymon Asia Capital (Singapore) Pte. Ltd. | 13,289 | $625.1K | 0.10% | +13,289 | New |
| Virtus Investment Advisers, Inc. | 13,220 | $621.9K | 0.14% | −8,507−39.2% | Reduced |
| Money Concepts Capital Corp | 13,000 | $611.5K | 0.03% | 00.0% | Unchanged |
| Xponance, Inc. | 12,716 | $598.2K | 0.00% | +12,716 | New |
| State of Wyoming | 12,448 | $585.6K | 0.06% | +12,448 | New |
| Axq Capital, LP | 12,444 | $585.4K | 0.06% | +12,444 | New |
| Stifel Financial Corp | 12,225 | $575.1K | 0.00% | −401−3.2% | Reduced |