Definium Therapeutics, Inc.
DFTX- 交易所
- Nasdaq
- 產業
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
近 90 天，Definium Therapeutics, Inc. 內部人申報 0 筆公開市場買進、1 筆賣出；2026 年第 2 季末有 362 家機構在 13F 申報持有，市值合計 $53.5 億；大師中只有杜肯家族辦公室持有。
2026 年第 2 季 13F 持有人
Definium Therapeutics, Inc. 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 362
- 較 2026 年第 1 季 +119 家
- 持有股數
- 1.15 億
- 較 2026 年第 1 季 +4,032 萬 (+54.1%)
- 總市值
- $53.5 億
- 較 2026 年第 1 季 +$39.4 億 (+280.1%)
- 新進機構
- 148
- 另有 117 家加碼
- 清倉機構
- 29
- 另有 64 家減碼
另有 5 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DFTX 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 362 | $53.5 億 |
| 2026 年第 1 季 | 248 | $14.7 億 |
| 2025 年第 4 季 | 209 | $9.09 億 |
| 2025 年第 3 季 | 196 | $4.69 億 |
| 2025 年第 2 季 | 183 | $2.71 億 |
| 2025 年第 1 季 | 191 | $2.41 億 |
| 2024 年第 4 季 | 174 | $2.89 億 |
| 2024 年第 3 季 | 158 | $2.82 億 |
| 2024 年第 2 季 | 152 | $2.99 億 |
| 2024 年第 1 季 | 135 | $3.27 億 |
| 2023 年第 4 季 | 104 | $1,787 萬 |
| 2023 年第 3 季 | 93 | $1,213 萬 |
| 2023 年第 2 季 | 84 | $1,389 萬 |
| 2023 年第 1 季 | 89 | $1,255 萬 |
| 2022 年第 4 季 | 104 | $1,114 萬 |
| 2022 年第 3 季 | 101 | $2,053 萬 |
| 2022 年第 2 季 | 156 | $1,510 萬 |
| 2022 年第 1 季 | 159 | $5,362 萬 |
| 2021 年第 4 季 | 176 | $7,205 萬 |
| 2021 年第 3 季 | 175 | $1.05 億 |
| 2021 年第 2 季 | 156 | $1.31 億 |
| 2021 年第 1 季 | 8 | $93.2 萬 |
2026 年第 2 季持有機構
每家機構持有 Definium Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock, Inc. | 11,232,834 | $5.28 億 | 0.01% | +2,752,604+32.5% | 加碼 |
| Avoro Capital Advisors LLC | 7,188,888 | $3.38 億 | 3.04% | +2,188,888+43.8% | 加碼 |
| Driehaus Capital Management LLC | 6,845,276 | $3.22 億 | 1.87% | +933,387+15.8% | 加碼 |
| Jupiter Topco LLC | 5,615,645 | $2.64 億 | 0.11% | +5,615,645 | 新進 |
| Capital World Investors | 5,367,723 | $2.52 億 | 0.03% | +5,367,723 | 新進 |
| FMR LLC | 4,752,921 | $2.24 億 | 0.01% | +2,943,311+162.6% | 加碼 |
| Price T Rowe Associates Inc | 4,652,032 | $2.19 億 | 0.02% | +4,582,031+6,545.7% | 加碼 |
| Geode Capital Management, LLC | 3,644,813 | $1.71 億 | 0.01% | +1,149,414+46.1% | 加碼 |
| State Street Corp | 3,065,390 | $1.44 億 | 0.00% | +593,517+24.0% | 加碼 |
| Capital International Investors | 2,963,410 | $1.39 億 | 0.03% | +2,963,410 | 新進 |
| Octagon Capital Advisors LP | 2,950,000 | $1.39 億 | 12.74% | +510,000+20.9% | 加碼 |
| Wellington Management Group LLP | 2,949,734 | $1.39 億 | 0.02% | +1,644,985+126.1% | 加碼 |
| Deep Track Capital, LP | 2,750,000 | $1.29 億 | 1.91% | −250,000−8.3% | 減碼 |
| Commodore Capital LP | 2,000,000 | $9,408 萬 | 5.60% | 00.0% | 不變 |
| Goldman Sachs Group Inc | 1,800,852 | $8,471 萬 | 0.01% | +125,441+7.5% | 加碼 |
| Citadel Advisors LLC | 1,688,587 | $7,943 萬 | 0.05% | +355,145+26.6% | 加碼 |
| Vanguard Portfolio Management LLC | 1,648,426 | $7,754 萬 | 0.00% | +775,761+88.9% | 加碼 |
| Ra Capital Management, L.P. | 1,500,000 | $7,056 萬 | 0.61% | +1,500,000 | 新進 |
| Vanguard Capital Management LLC | 1,486,454 | $6,992 萬 | 0.00% | +389,476+35.5% | 加碼 |
| Siren, L.L.C. | 1,419,493 | $6,677 萬 | 1.36% | +500,000+54.4% | 加碼 |
| Marshall Wace, LLP | 1,298,946 | $6,110 萬 | 0.05% | +98,121+8.2% | 加碼 |
| Northern Trust Corp | 1,169,238 | $5,500 萬 | 0.01% | +370,251+46.3% | 加碼 |
| Ameriprise Financial Inc | 1,148,363 | $5,402 萬 | 0.01% | +181,755+18.8% | 加碼 |
| Nuveen, LLC | 1,105,314 | $5,199 萬 | 0.01% | +407,184+58.3% | 加碼 |
| Charles Schwab Investment Management Inc | 1,083,576 | $5,097 萬 | 0.01% | +274,861+34.0% | 加碼 |
| Woodline Partners LP | 1,003,641 | $4,721 萬 | 0.15% | +250,849+33.3% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,000,000 | $4,704 萬 | 0.07% | −150,000−13.0% | 減碼 |
| Boxer Capital Management, LLC | 998,500 | $4,697 萬 | 3.54% | +400,000+66.8% | 加碼 |
| Two Sigma Investments, LP | 921,818 | $4,336 萬 | 0.03% | −279,792−23.3% | 減碼 |
| Balyasny Asset Management LLC | 897,658 | $4,223 萬 | 0.08% | −376,563−29.6% | 減碼 |
| Vanguard Fiduciary Trust Co | 827,693 | $3,893 萬 | 0.01% | +251,756+43.7% | 加碼 |
| Holocene Advisors, LP | 796,574 | $3,747 萬 | 0.09% | −295,393−27.1% | 減碼 |
| AWM Investment Company, Inc. | 784,800 | $3,692 萬 | 3.20% | −292,093−27.1% | 減碼 |
| Bank of New York Mellon Corp | 777,271 | $3,656 萬 | 0.01% | +24,349+3.2% | 加碼 |
| Polar Capital Holdings Plc | 777,253 | $3,656 萬 | 0.10% | +777,253 | 新進 |
| Alliancebernstein L.P. | 1,803,287 | $3,408 萬 | 0.01% | +1,711,584+1,866.4% | 加碼 |
| Eventide Asset Management, LLC | 710,000 | $3,340 萬 | 0.45% | +23,838+3.5% | 加碼 |
| Neuberger Berman Group LLC | 687,539 | $3,234 萬 | 0.02% | +554,170+415.5% | 加碼 |
| Qube Research & Technologies Ltd | 682,901 | $3,212 萬 | 0.04% | +256,846+60.3% | 加碼 |
| Candriam Luxembourg S.C.A. | 614,425 | $2,887 萬 | 0.13% | −679,204−52.5% | 減碼 |
| ArrowMark Colorado Holdings LLC | 564,069 | $2,653 萬 | 1.10% | −1,030,648−64.6% | 減碼 |
| Catalio Capital Management, LP | 562,672 | $2,647 萬 | 4.97% | −475,312−45.8% | 減碼 |
| Blackstone Group Inc. | 561,612 | $2,642 萬 | 0.09% | +52,944+10.4% | 加碼 |
| Integral Health Asset Management, LLC | 550,000 | $2,587 萬 | 1.06% | +150,000+37.5% | 加碼 |
| Bamco Inc | 520,108 | $2,447 萬 | 0.04% | +520,108 | 新進 |
| UBS Group AG | 499,467 | $2,349 萬 | 0.00% | +5,490+1.1% | 加碼 |
| Franklin Resources Inc | 486,219 | $2,287 萬 | 0.00% | +486,219 | 新進 |
| Point72 Asset Management, L.P. | 483,980 | $2,277 萬 | 0.03% | +308,490+175.8% | 加碼 |
| Ensign Peak Advisors, Inc | 466,106 | $2,193 萬 | 0.04% | −80,677−14.8% | 減碼 |
| Morgan Stanley | 454,912 | $2,140 萬 | 0.00% | +16,339+3.7% | 加碼 |
| Great Point Partners LLC | 425,000 | $1,999 萬 | 4.71% | +425,000 | 新進 |
| RTW Investments, LP | 400,000 | $1,882 萬 | 0.16% | +100,000+33.3% | 加碼 |
| Cormorant Asset Management, LP | 400,000 | $1,882 萬 | 0.96% | +400,000 | 新進 |
| Silverarc Capital Management, LLC | 400,000 | $1,882 萬 | 2.09% | +400,000 | 新進 |
| Assetmark, Inc | 396,542 | $1,865 萬 | 0.03% | +396,542 | 新進 |
| OrbiMed Advisors LLC | 365,400 | $1,719 萬 | 0.33% | −438,600−54.6% | 減碼 |
| Duquesne Family Office LLC大師杜肯家族辦公室 | 356,600 | $1,677 萬 | 0.39% | +356,600 | 新進 |
| D. E. Shaw & Co., Inc. | 315,410 | $1,484 萬 | 0.01% | +43,693+16.1% | 加碼 |
| Polygon Management Ltd. | 286,990 | $1,350 萬 | 2.20% | +86,996+43.5% | 加碼 |
| Millennium Management LLC | 266,076 | $1,252 萬 | 0.01% | −580,820−68.6% | 減碼 |
| JPMorgan Chase & Co | 265,955 | $1,238 萬 | 0.00% | +1,410+0.5% | 加碼 |
| Sofinnova Investments, Inc. | 255,903 | $1,204 萬 | 0.64% | −88,263−25.6% | 減碼 |
| PFM Health Sciences, LP | 249,020 | $1,171 萬 | 1.02% | +43,703+21.3% | 加碼 |
| HighVista Strategies LLC | 242,884 | $1,143 萬 | 2.60% | +57,028+30.7% | 加碼 |
| Trexquant Investment LP | 233,199 | $1,097 萬 | 0.07% | +233,199 | 新進 |
| Seven Grand Managers, LLC | 225,000 | $1,058 萬 | 0.43% | 00.0% | 不變 |
| Swiss National Bank | 221,200 | $1,041 萬 | 0.01% | +62,800+39.6% | 加碼 |
| Eversept Partners, LP | 217,185 | $1,022 萬 | 0.56% | +56,462+35.1% | 加碼 |
| UBS Asset Management Americas Inc | 211,183 | $993.4 萬 | 0.00% | +208,770+8,651.9% | 加碼 |
| TD Asset Management Inc | 209,460 | $985.3 萬 | 0.01% | +209,460 | 新進 |
| Royce & Associates LP | 208,551 | $981.0 萬 | 0.08% | −25,500−10.9% | 減碼 |
| SEB Asset Management AB | 208,254 | $979.6 萬 | 0.04% | +208,254 | 新進 |
| Superstring Capital Management LP | 188,282 | $885.7 萬 | 5.59% | −163,179−46.4% | 減碼 |
| Emerald Advisers, LLC | 178,751 | $840.8 萬 | 0.20% | +178,751 | 新進 |
| Standard Life Aberdeen plc | 175,000 | $823.2 萬 | 0.01% | +175,000 | 新進 |
| Bank of America Corp | 164,575 | $774.2 萬 | 0.00% | +6,230+3.9% | 加碼 |
| Tri Locum Partners LP | 162,996 | $766.7 萬 | 0.94% | −206,592−55.9% | 減碼 |
| Rhumbline Advisers | 158,096 | $743.7 萬 | 0.01% | +38,124+31.8% | 加碼 |
| Brevan Howard Capital Management LP | 156,812 | $737.6 萬 | 0.10% | −54,676−25.9% | 減碼 |
| Russell Investments Group, Ltd. | 153,477 | $722.0 萬 | 0.01% | +34,013+28.5% | 加碼 |
| LMR Partners LLP | 150,200 | $706.5 萬 | 0.05% | +150,200 | 新進 |
| Seven Fleet Capital Management LP | 148,647 | $699.2 萬 | 1.15% | +48,760+48.8% | 加碼 |
| Manufacturers Life Insurance Company, The | 146,368 | $688.5 萬 | 0.01% | +119,964+454.3% | 加碼 |
| Rock Springs Capital Management LP | 143,187 | $673.6 萬 | 0.33% | +143,187 | 新進 |
| Deutsche Bank AG | 142,947 | $672.4 萬 | 0.00% | −268,887−65.3% | 減碼 |
| SummitTX Capital, L.P. | 142,489 | $670.3 萬 | 0.18% | +142,489 | 新進 |
| StemPoint Capital LP | 137,124 | $645.0 萬 | 1.12% | −188,359−57.9% | 減碼 |
| AQR Capital Management LLC | 134,152 | $631.1 萬 | 0.00% | +77,058+135.0% | 加碼 |
| California State Teachers Retirement System | 128,346 | $603.7 萬 | 0.01% | +128,346 | 新進 |
| BIT Capital GmbH | 128,131 | $602.7 萬 | 0.21% | −149,380−53.8% | 減碼 |
| Fred Alger Management, LLC | 125,256 | $589.2 萬 | 0.02% | +33,091+35.9% | 加碼 |
| Wells Fargo & Company | 122,033 | $574.0 萬 | 0.00% | +82,060+205.3% | 加碼 |
| Atika Capital Management LLC | 122,000 | $573.9 萬 | 0.57% | +122,000 | 新進 |
| AdvisorShares Investments LLC | 121,381 | $571.0 萬 | 0.69% | +30,080+32.9% | 加碼 |
| Emerald Mutual Fund Advisers Trust | 121,249 | $570.4 萬 | 0.20% | +121,249 | 新進 |
| EAM Investors, LLC | 120,928 | $568.8 萬 | 0.51% | +120,928 | 新進 |
| Schonfeld Strategic Advisors LLC | 119,610 | $562.6 萬 | 0.03% | +109,198+1,048.8% | 加碼 |
| HSBC Holdings PLC | 117,482 | $552.6 萬 | 0.00% | +117,482 | 新進 |
| Alps Advisors Inc | 110,388 | $519.3 萬 | 0.02% | +110,388 | 新進 |
| Data Collective IV GP, LLC | 100,350 | $472.0 萬 | 6.01% | 00.0% | 不變 |