Definium Therapeutics, Inc.
DFTX- 交易所
- Nasdaq
- 產業
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
近 90 天，Definium Therapeutics, Inc. 內部人申報 0 筆公開市場買進、1 筆賣出；2026 年第 2 季末有 362 家機構在 13F 申報持有，市值合計 $53.5 億；大師中只有杜肯家族辦公室持有。
2026 年第 1 季 13F 持有人
Definium Therapeutics, Inc. 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 248
- 較 2025 年第 4 季 +42 家
- 持有股數
- 7,805 萬
- 較 2025 年第 4 季 +1,278 萬 (+19.6%)
- 總市值
- $14.7 億
- 較 2025 年第 4 季 +$6.01 億 (+68.7%)
- 新進機構
- 69
- 另有 82 家加碼
- 清倉機構
- 27
- 另有 53 家減碼
另有 3 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DFTX 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 362 | $53.5 億 |
| 2026 年第 1 季 | 248 | $14.7 億 |
| 2025 年第 4 季 | 209 | $9.09 億 |
| 2025 年第 3 季 | 196 | $4.69 億 |
| 2025 年第 2 季 | 183 | $2.71 億 |
| 2025 年第 1 季 | 191 | $2.41 億 |
| 2024 年第 4 季 | 174 | $2.89 億 |
| 2024 年第 3 季 | 158 | $2.82 億 |
| 2024 年第 2 季 | 152 | $2.99 億 |
| 2024 年第 1 季 | 135 | $3.27 億 |
| 2023 年第 4 季 | 104 | $1,787 萬 |
| 2023 年第 3 季 | 93 | $1,213 萬 |
| 2023 年第 2 季 | 84 | $1,389 萬 |
| 2023 年第 1 季 | 89 | $1,255 萬 |
| 2022 年第 4 季 | 104 | $1,114 萬 |
| 2022 年第 3 季 | 101 | $2,053 萬 |
| 2022 年第 2 季 | 156 | $1,510 萬 |
| 2022 年第 1 季 | 159 | $5,362 萬 |
| 2021 年第 4 季 | 176 | $7,205 萬 |
| 2021 年第 3 季 | 175 | $1.05 億 |
| 2021 年第 2 季 | 156 | $1.31 億 |
| 2021 年第 1 季 | 8 | $93.2 萬 |
2026 年第 1 季持有機構
每家機構持有 Definium Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock, Inc. | 8,480,230 | $1.60 億 | 0.00% | +206,954+2.5% | 加碼 |
| Driehaus Capital Management LLC | 5,911,889 | $1.12 億 | 0.82% | −625,313−9.6% | 減碼 |
| Avoro Capital Advisors LLC | 5,000,000 | $9,450 萬 | 0.93% | 00.0% | 不變 |
| Janus Henderson Group PLC | 3,556,041 | $6,723 萬 | 0.03% | +1,144,345+47.4% | 加碼 |
| Deep Track Capital, LP | 3,000,000 | $5,670 萬 | 1.17% | +1,323,460+78.9% | 加碼 |
| Geode Capital Management, LLC | 2,495,399 | $4,717 萬 | 0.00% | +162,461+7.0% | 加碼 |
| State Street Corp | 2,471,873 | $4,672 萬 | 0.00% | +103,807+4.4% | 加碼 |
| Octagon Capital Advisors LP | 2,440,000 | $4,612 萬 | 5.10% | +210,000+9.4% | 加碼 |
| Commodore Capital LP | 2,000,000 | $3,780 萬 | 2.19% | 00.0% | 不變 |
| FMR LLC | 1,809,610 | $3,420 萬 | 0.00% | +1,647,557+1,016.7% | 加碼 |
| Trails Edge Capital Partners, LP | 1,738,110 | $3,285 萬 | 7.73% | −830,000−32.3% | 減碼 |
| Goldman Sachs Group Inc | 1,675,411 | $3,167 萬 | 0.00% | +750,079+81.1% | 加碼 |
| ArrowMark Colorado Holdings LLC | 1,594,717 | $3,014 萬 | 0.80% | +1,594,717 | 新進 |
| Citadel Advisors LLC | 1,333,442 | $2,520 萬 | 0.02% | +1,123,498+535.1% | 加碼 |
| Wellington Management Group LLP | 1,304,749 | $2,466 萬 | 0.00% | +84,082+6.9% | 加碼 |
| Candriam Luxembourg S.C.A. | 1,293,629 | $2,445 萬 | 0.13% | +322,411+33.2% | 加碼 |
| Balyasny Asset Management LLC | 1,274,221 | $2,408 萬 | 0.05% | −33,894−2.6% | 減碼 |
| Two Sigma Investments, LP | 1,201,610 | $2,271 萬 | 0.02% | +776,403+182.6% | 加碼 |
| Marshall Wace, LLP | 1,200,825 | $2,270 萬 | 0.02% | −1,774,877−59.6% | 減碼 |
| Adage Capital Partners GP, L.L.C. | 1,150,000 | $2,174 萬 | 0.03% | 00.0% | 不變 |
| Vanguard Capital Management LLC | 1,096,978 | $2,073 萬 | 0.00% | +1,096,978 | 新進 |
| Holocene Advisors, LP | 1,091,967 | $2,064 萬 | 0.05% | +1,091,967 | 新進 |
| AWM Investment Company, Inc. | 1,076,893 | $2,035 萬 | 2.25% | −313,769−22.6% | 減碼 |
| Catalio Capital Management, LP | 1,037,984 | $1,962 萬 | 4.10% | +1,037,984 | 新進 |
| Ameriprise Financial Inc | 966,608 | $1,827 萬 | 0.00% | +462,367+91.7% | 加碼 |
| Siren, L.L.C. | 919,493 | $1,738 萬 | 0.48% | +119,493+14.9% | 加碼 |
| Vanguard Portfolio Management LLC | 872,665 | $1,649 萬 | 0.00% | +872,665 | 新進 |
| Millennium Management LLC | 846,896 | $1,601 萬 | 0.01% | −536,279−38.8% | 減碼 |
| Charles Schwab Investment Management Inc | 808,715 | $1,528 萬 | 0.00% | +1,466+0.2% | 加碼 |
| OrbiMed Advisors LLC | 804,000 | $1,520 萬 | 0.35% | −422,700−34.5% | 減碼 |
| Northern Trust Corp | 798,987 | $1,510 萬 | 0.00% | +64,327+8.8% | 加碼 |
| Bank of New York Mellon Corp | 752,922 | $1,423 萬 | 0.00% | +454,262+152.1% | 加碼 |
| Woodline Partners LP | 752,792 | $1,423 萬 | 0.05% | +602,222+400.0% | 加碼 |
| Nuveen, LLC | 698,130 | $1,319 萬 | 0.00% | +421,676+152.5% | 加碼 |
| Eventide Asset Management, LLC | 686,162 | $1,297 萬 | 0.21% | +686,162 | 新進 |
| Boxer Capital Management, LLC | 598,500 | $1,131 萬 | 1.49% | 00.0% | 不變 |
| Vanguard Fiduciary Trust Co | 575,937 | $1,089 萬 | 0.00% | +575,937 | 新進 |
| Ensign Peak Advisors, Inc | 546,783 | $1,033 萬 | 0.02% | +284,783+108.7% | 加碼 |
| Blackstone Group Inc. | 508,668 | $961.4 萬 | 0.04% | −1,551,137−75.3% | 減碼 |
| UBS Group AG | 493,977 | $933.6 萬 | 0.00% | −189,825−27.8% | 減碼 |
| Morgan Stanley | 438,573 | $828.9 萬 | 0.00% | +71,878+19.6% | 加碼 |
| Qube Research & Technologies Ltd | 426,055 | $805.2 萬 | 0.01% | +426,055 | 新進 |
| Deutsche Bank AG | 411,834 | $778.4 萬 | 0.00% | +13,565+3.4% | 加碼 |
| Integral Health Asset Management, LLC | 400,000 | $756.0 萬 | 0.40% | +50,000+14.3% | 加碼 |
| Tri Locum Partners LP | 369,588 | $698.5 萬 | 0.98% | +369,588 | 新進 |
| Superstring Capital Management LP | 351,461 | $664.3 萬 | 4.75% | −73,741−17.3% | 減碼 |
| Sofinnova Investments, Inc. | 344,166 | $650.5 萬 | 0.33% | +344,166 | 新進 |
| Patient Square Capital LP | 331,000 | $625.6 萬 | 1.11% | +331,000 | 新進 |
| StemPoint Capital LP | 325,483 | $615.2 萬 | 1.18% | +325,483 | 新進 |
| RTW Investments, LP | 300,000 | $567.0 萬 | 0.06% | 00.0% | 不變 |
| BIT Capital GmbH | 277,511 | $524.5 萬 | 0.29% | +277,511 | 新進 |
| D. E. Shaw & Co., Inc. | 271,717 | $513.5 萬 | 0.00% | −22,005−7.5% | 減碼 |
| Jane Street Group, LLC | 260,241 | $491.9 萬 | 0.01% | −275,761−51.4% | 減碼 |
| JPMorgan Chase & Co | 264,545 | $463.0 萬 | 0.00% | +110,823+72.1% | 加碼 |
| Royce & Associates LP | 234,051 | $442.4 萬 | 0.04% | +70,010+42.7% | 加碼 |
| Seven Grand Managers, LLC | 225,000 | $425.3 萬 | 0.28% | 00.0% | 不變 |
| Brevan Howard Capital Management LP | 211,488 | $399.7 萬 | 0.04% | +200,374+1,802.9% | 加碼 |
| PFM Health Sciences, LP | 205,317 | $388.0 萬 | 0.41% | +205,317 | 新進 |
| Polygon Management Ltd. | 199,994 | $378.0 萬 | 0.74% | +199,994 | 新進 |
| HighVista Strategies LLC | 185,856 | $351.3 萬 | 0.97% | +185,856 | 新進 |
| Point72 Asset Management, L.P. | 175,490 | $331.7 萬 | 0.01% | −4,951−2.7% | 減碼 |
| Eversept Partners, LP | 160,723 | $303.8 萬 | 0.20% | +160,723 | 新進 |
| Swiss National Bank | 158,400 | $299.4 萬 | 0.00% | 00.0% | 不變 |
| Bank of America Corp | 158,345 | $299.3 萬 | 0.00% | +47,878+43.3% | 加碼 |
| Soviero Asset Management, LP | 140,000 | $264.6 萬 | 1.49% | −10,000−6.7% | 減碼 |
| Neuberger Berman Group LLC | 133,369 | $252.1 萬 | 0.00% | +133,369 | 新進 |
| Squarepoint Ops LLC | 125,522 | $237.2 萬 | 0.01% | +80,120+176.5% | 加碼 |
| Rosalind Advisors, Inc. | 125,000 | $236.3 萬 | 0.97% | −625,000−83.3% | 減碼 |
| Rhumbline Advisers | 119,972 | $226.7 萬 | 0.00% | +9,225+8.3% | 加碼 |
| Russell Investments Group, Ltd. | 119,464 | $225.8 萬 | 0.00% | +110,599+1,247.6% | 加碼 |
| ExodusPoint Capital Management, LP | 104,915 | $198.3 萬 | 0.02% | +85,967+453.7% | 加碼 |
| Data Collective IV GP, LLC | 100,350 | $189.7 萬 | 3.39% | 00.0% | 不變 |
| Burkehill Global Management, LP | 100,000 | $189.0 萬 | 0.09% | 00.0% | 不變 |
| Seven Fleet Capital Management LP | 99,887 | $188.8 萬 | 0.59% | +99,887 | 新進 |
| Royal Bank of Canada | 97,192 | $183.6 萬 | 0.00% | +3,566+3.8% | 加碼 |
| Fred Alger Management, LLC | 92,165 | $174.2 萬 | 0.01% | +92,165 | 新進 |
| Alliancebernstein L.P. | 91,703 | $173.3 萬 | 0.00% | +16,866+22.5% | 加碼 |
| AdvisorShares Investments LLC | 91,301 | $172.6 萬 | 0.31% | −11,537−11.2% | 減碼 |
| HRT Financial LP | 89,141 | $168.4 萬 | 0.00% | +62,859+239.2% | 加碼 |
| Invesco Ltd. | 88,121 | $166.5 萬 | 0.00% | +34,739+65.1% | 加碼 |
| Group One Trading, L.P. | 87,832 | $166.0 萬 | 0.05% | +87,832 | 新進 |
| Susquehanna International Group, LLP | 81,456 | $154.0 萬 | 0.00% | −395,656−82.9% | 減碼 |
| LPL Financial LLC | 78,271 | $147.9 萬 | 0.00% | +1,035+1.3% | 加碼 |
| Price T Rowe Associates Inc | 70,001 | $132.4 萬 | 0.00% | +17,771+34.0% | 加碼 |
| Platinum Investment Management Ltd | 70,000 | $132.3 萬 | 0.33% | 00.0% | 不變 |
| Legal & General Group Plc | 59,799 | $113.0 萬 | 0.00% | −7,176−10.7% | 減碼 |
| Ikarian Capital, LLC | 58,803 | $111.1 萬 | 0.16% | 00.0% | 不變 |
| AQR Capital Management LLC | 57,094 | $107.9 萬 | 0.00% | −1,204−2.1% | 減碼 |
| Rockefeller Capital Management L.P. | 55,206 | $104.3 萬 | 0.00% | +54,855+15,628.2% | 加碼 |
| MetLife Investment Management | 54,261 | $102.6 萬 | 0.01% | +1,681+3.2% | 加碼 |
| Vanguard Asset Management, Ltd | 54,018 | $102.1 萬 | 0.00% | +54,018 | 新進 |
| Blair William & Co | 53,695 | $101.5 萬 | 0.00% | +53,695 | 新進 |
| Kestra Private Wealth Services, LLC | 50,588 | $95.6 萬 | 0.01% | +448+0.9% | 加碼 |
| State of Wisconsin Investment Board | 50,420 | $95.3 萬 | 0.00% | −8,182−14.0% | 減碼 |
| Nisa Investment Advisors, LLC | 48,903 | $92.4 萬 | 0.00% | +525+1.1% | 加碼 |
| Vanguard Global Advisers, LLC | 48,044 | $90.8 萬 | 0.00% | +48,044 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 46,193 | $87.3 萬 | 0.00% | +2,457+5.6% | 加碼 |
| Allstate Corp | 45,366 | $85.7 萬 | 0.01% | +45,366 | 新進 |
| CenterBook Partners LP | 42,829 | $80.9 萬 | 0.04% | −95,986−69.1% | 減碼 |
| Twinbeech Capital LP | 42,100 | $79.6 萬 | 0.08% | +42,100 | 新進 |