Definium Therapeutics, Inc.
DFTX- 交易所
- Nasdaq
- 產業
- Medicinal Chemicals & Botanical Products
- SEC CIK
- 0001813814
近 90 天，Definium Therapeutics, Inc. 內部人申報 0 筆公開市場買進、1 筆賣出；2026 年第 2 季末有 362 家機構在 13F 申報持有，市值合計 $53.5 億；大師中只有杜肯家族辦公室持有。
2025 年第 4 季 13F 持有人
Definium Therapeutics, Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 209
- 較 2025 年第 3 季 +20 家
- 持有股數
- 6,786 萬
- 較 2025 年第 3 季 +2,833 萬 (+71.7%)
- 總市值
- $9.09 億
- 較 2025 年第 3 季 +$4.43 億 (+95.0%)
- 新進機構
- 50
- 另有 92 家加碼
- 清倉機構
- 30
- 另有 31 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DFTX 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 362 | $53.5 億 |
| 2026 年第 1 季 | 248 | $14.7 億 |
| 2025 年第 4 季 | 209 | $9.09 億 |
| 2025 年第 3 季 | 196 | $4.69 億 |
| 2025 年第 2 季 | 183 | $2.71 億 |
| 2025 年第 1 季 | 191 | $2.41 億 |
| 2024 年第 4 季 | 174 | $2.89 億 |
| 2024 年第 3 季 | 158 | $2.82 億 |
| 2024 年第 2 季 | 152 | $2.99 億 |
| 2024 年第 1 季 | 135 | $3.27 億 |
| 2023 年第 4 季 | 104 | $1,787 萬 |
| 2023 年第 3 季 | 93 | $1,213 萬 |
| 2023 年第 2 季 | 84 | $1,389 萬 |
| 2023 年第 1 季 | 89 | $1,255 萬 |
| 2022 年第 4 季 | 104 | $1,114 萬 |
| 2022 年第 3 季 | 101 | $2,053 萬 |
| 2022 年第 2 季 | 156 | $1,510 萬 |
| 2022 年第 1 季 | 159 | $5,362 萬 |
| 2021 年第 4 季 | 176 | $7,205 萬 |
| 2021 年第 3 季 | 175 | $1.05 億 |
| 2021 年第 2 季 | 156 | $1.31 億 |
| 2021 年第 1 季 | 8 | $93.2 萬 |
2025 年第 4 季持有機構
每家機構持有 Definium Therapeutics, Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock, Inc. | 8,273,276 | $1.11 億 | 0.00% | +2,337,719+39.4% | 加碼 |
| Driehaus Capital Management LLC | 6,537,202 | $8,753 萬 | 0.59% | +3,427,291+110.2% | 加碼 |
| Avoro Capital Advisors LLC | 5,000,000 | $6,695 萬 | 0.66% | +5,000,000 | 新進 |
| Marshall Wace, LLP | 2,975,702 | $3,984 萬 | 0.04% | +593,722+24.9% | 加碼 |
| Vanguard Group Inc | 2,591,901 | $3,471 萬 | 0.00% | +579,027+28.8% | 加碼 |
| Trails Edge Capital Partners, LP | 2,568,110 | $3,439 萬 | 8.50% | +2,568,110 | 新進 |
| Janus Henderson Group PLC | 2,411,696 | $3,226 萬 | 0.01% | +2,383,696+8,513.2% | 加碼 |
| State Street Corp | 2,368,066 | $3,171 萬 | 0.00% | +443,173+23.0% | 加碼 |
| Geode Capital Management, LLC | 2,332,938 | $3,124 萬 | 0.00% | +508,237+27.9% | 加碼 |
| Octagon Capital Advisors LP | 2,230,000 | $2,986 萬 | 3.74% | +100,000+4.7% | 加碼 |
| Blackstone Group Inc. | 2,059,805 | $2,758 萬 | 0.12% | −716,756−25.8% | 減碼 |
| Commodore Capital LP | 2,000,000 | $2,678 萬 | 1.78% | −1,225,000−38.0% | 減碼 |
| Deep Track Capital, LP | 1,676,540 | $2,245 萬 | 0.51% | +176,540+11.8% | 加碼 |
| AWM Investment Company, Inc. | 1,390,662 | $1,862 萬 | 1.80% | +175,000+14.4% | 加碼 |
| Millennium Management LLC | 1,383,175 | $1,852 萬 | 0.01% | +1,084,970+363.8% | 加碼 |
| Balyasny Asset Management LLC | 1,308,115 | $1,752 萬 | 0.03% | +1,308,115 | 新進 |
| OrbiMed Advisors LLC | 1,226,700 | $1,643 萬 | 0.34% | +858,876+233.5% | 加碼 |
| Wellington Management Group LLP | 1,220,667 | $1,634 萬 | 0.00% | +964,301+376.1% | 加碼 |
| Adage Capital Partners GP, L.L.C. | 1,150,000 | $1,540 萬 | 0.02% | +850,000+283.3% | 加碼 |
| Candriam Luxembourg S.C.A. | 971,218 | $1,301 萬 | 0.06% | +971,218 | 新進 |
| Goldman Sachs Group Inc | 925,332 | $1,239 萬 | 0.00% | +374,702+68.0% | 加碼 |
| Charles Schwab Investment Management Inc | 807,249 | $1,081 萬 | 0.00% | +173,547+27.4% | 加碼 |
| Siren, L.L.C. | 800,000 | $1,071 萬 | 0.32% | +800,000 | 新進 |
| Rosalind Advisors, Inc. | 750,000 | $1,004 萬 | 3.85% | 00.0% | 不變 |
| Northern Trust Corp | 734,660 | $983.7 萬 | 0.00% | +106,122+16.9% | 加碼 |
| UBS Group AG | 683,802 | $915.6 萬 | 0.00% | +131,993+23.9% | 加碼 |
| Vestal Point Capital, LP | 637,000 | $852.9 萬 | 0.31% | +637,000 | 新進 |
| Boxer Capital Management, LLC | 598,500 | $801.4 萬 | 1.75% | +435,000+266.1% | 加碼 |
| Jane Street Group, LLC | 536,002 | $717.7 萬 | 0.01% | +261,154+95.0% | 加碼 |
| Ameriprise Financial Inc | 504,241 | $675.2 萬 | 0.00% | +504,241 | 新進 |
| Susquehanna International Group, LLP | 477,112 | $638.9 萬 | 0.01% | +459,839+2,662.2% | 加碼 |
| Two Sigma Investments, LP | 425,207 | $569.4 萬 | 0.01% | +128,764+43.4% | 加碼 |
| Superstring Capital Management LP | 425,202 | $569.3 萬 | 3.05% | +425,202 | 新進 |
| Deutsche Bank AG | 398,269 | $533.3 萬 | 0.00% | +343,109+622.0% | 加碼 |
| Morgan Stanley | 366,695 | $491.0 萬 | 0.00% | −128,923−26.0% | 減碼 |
| Integral Health Asset Management, LLC | 350,000 | $468.6 萬 | 0.24% | +350,000 | 新進 |
| RTW Investments, LP | 300,000 | $401.7 萬 | 0.04% | +300,000 | 新進 |
| Bank of New York Mellon Corp | 298,660 | $399.9 萬 | 0.00% | +69,629+30.4% | 加碼 |
| D. E. Shaw & Co., Inc. | 293,722 | $393.3 萬 | 0.00% | +77,388+35.8% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 278,720 | $373.2 萬 | 0.01% | +278,720 | 新進 |
| Nuveen, LLC | 276,454 | $370.2 萬 | 0.00% | +42,950+18.4% | 加碼 |
| Ensign Peak Advisors, Inc | 262,000 | $350.8 萬 | 0.01% | +262,000 | 新進 |
| Seven Grand Managers, LLC | 225,000 | $301.3 萬 | 0.23% | +225,000 | 新進 |
| Citadel Advisors LLC | 209,944 | $281.1 萬 | 0.00% | −129,494−38.1% | 減碼 |
| Barclays PLC | 183,623 | $245.9 萬 | 0.00% | +33,018+21.9% | 加碼 |
| Point72 Asset Management, L.P. | 180,441 | $241.6 萬 | 0.00% | −43,859−19.6% | 減碼 |
| Royce & Associates LP | 164,041 | $219.7 萬 | 0.02% | +83,017+102.5% | 加碼 |
| FMR LLC | 162,053 | $217.0 萬 | 0.00% | +146,495+941.6% | 加碼 |
| Swiss National Bank | 158,400 | $212.1 萬 | 0.00% | +41,300+35.3% | 加碼 |
| JPMorgan Chase & Co | 153,722 | $205.8 萬 | 0.00% | +110,540+256.0% | 加碼 |
| Woodline Partners LP | 150,570 | $201.6 萬 | 0.01% | +150,570 | 新進 |
| Soviero Asset Management, LP | 150,000 | $200.8 萬 | 1.05% | +150,000 | 新進 |
| CenterBook Partners LP | 138,815 | $185.9 萬 | 0.09% | −20,606−12.9% | 減碼 |
| Verition Fund Management LLC | 132,263 | $177.1 萬 | 0.01% | +132,263 | 新進 |
| Rhumbline Advisers | 110,747 | $148.3 萬 | 0.00% | −1,371−1.2% | 減碼 |
| Bank of America Corp | 110,467 | $147.9 萬 | 0.00% | +26,456+31.5% | 加碼 |
| Wells Fargo & Company | 107,057 | $143.3 萬 | 0.00% | +50,562+89.5% | 加碼 |
| AdvisorShares Investments LLC | 102,838 | $137.7 萬 | 0.23% | −18,826−15.5% | 減碼 |
| Data Collective IV GP, LLC | 100,350 | $134.4 萬 | 2.30% | 00.0% | 不變 |
| Burkehill Global Management, LP | 100,000 | $133.9 萬 | 0.09% | +100,000 | 新進 |
| Royal Bank of Canada | 93,626 | $125.4 萬 | 0.00% | +41,867+80.9% | 加碼 |
| LPL Financial LLC | 77,236 | $103.4 萬 | 0.00% | +1,289+1.7% | 加碼 |
| Alliancebernstein L.P. | 74,837 | $100.2 萬 | 0.00% | +70.0% | 加碼 |
| Platinum Investment Management Ltd | 70,000 | $93.7 萬 | 0.22% | +70,000 | 新進 |
| Legal & General Group Plc | 66,975 | $89.7 萬 | 0.00% | +11,956+21.7% | 加碼 |
| Two Sigma Advisers, LP | 65,281 | $87.4 萬 | 0.00% | −16,202−19.9% | 減碼 |
| Ikarian Capital, LLC | 58,803 | $78.7 萬 | 0.10% | −3,888−6.2% | 減碼 |
| State of Wisconsin Investment Board | 58,602 | $78.5 萬 | 0.00% | +58,602 | 新進 |
| California State Teachers Retirement System | 58,383 | $78.2 萬 | 0.00% | +1,092+1.9% | 加碼 |
| AQR Capital Management LLC | 58,298 | $78.1 萬 | 0.00% | +36,702+169.9% | 加碼 |
| Jennison Associates LLC | 53,785 | $72.0 萬 | 0.00% | +53,785 | 新進 |
| Invesco Ltd. | 53,382 | $71.5 萬 | 0.00% | +13,253+33.0% | 加碼 |
| MetLife Investment Management | 52,580 | $70.4 萬 | 0.00% | +3,384+6.9% | 加碼 |
| Gsa Capital Partners LLP | 52,255 | $70.0 萬 | 0.06% | −3,234−5.8% | 減碼 |
| Price T Rowe Associates Inc | 52,230 | $70.0 萬 | 0.00% | +11,025+26.8% | 加碼 |
| Kestra Private Wealth Services, LLC | 50,140 | $67.1 萬 | 0.01% | 00.0% | 不變 |
| Scotia Capital Inc. | 49,677 | $66.4 萬 | 0.00% | −4,254−7.9% | 減碼 |
| Nisa Investment Advisors, LLC | 48,378 | $64.8 萬 | 0.00% | 00.0% | 不變 |
| Simplex Trading, LLC | 48,226 | $64.6 萬 | 0.02% | +7,061+17.2% | 加碼 |
| Squarepoint Ops LLC | 45,402 | $60.8 萬 | 0.00% | +45,402 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 43,736 | $58.6 萬 | 0.00% | +8,339+23.6% | 加碼 |
| Citigroup Inc | 41,463 | $55.5 萬 | 0.00% | +18,000+76.7% | 加碼 |
| Quantinno Capital Management LP | 39,324 | $52.7 萬 | 0.00% | +3,582+10.0% | 加碼 |
| Palumbo Wealth Management LLC | 39,002 | $52.2 萬 | 0.13% | +6,073+18.4% | 加碼 |
| PSP Research LLC | 34,841 | $46.7 萬 | 0.41% | +34,841 | 新進 |
| Scientech Research LLC | 31,699 | $42.4 萬 | 0.27% | +7,460+30.8% | 加碼 |
| Fox Run Management, L.L.C. | 30,708 | $41.1 萬 | 0.06% | −20,984−40.6% | 減碼 |
| Dark Forest Capital Management LP | 30,661 | $41.1 萬 | 0.02% | +30,661 | 新進 |
| Schonfeld Strategic Advisors LLC | 30,456 | $40.8 萬 | 0.00% | −5,054−14.2% | 減碼 |
| Rathbone Brothers plc | 30,200 | $40.4 萬 | 0.00% | 00.0% | 不變 |
| Intech Investment Management LLC | 29,655 | $39.7 萬 | 0.00% | +2,521+9.3% | 加碼 |
| New York State Common Retirement Fund | 29,600 | $39.6 萬 | 0.00% | +12,500+73.1% | 加碼 |
| Manufacturers Life Insurance Company, The | 28,322 | $37.9 萬 | 0.00% | +3,004+11.9% | 加碼 |
| HRT Financial LP | 26,282 | $35.1 萬 | 0.00% | −31,283−54.3% | 減碼 |
| Police & Firemen's Retirement System of New Jersey | 25,207 | $33.8 萬 | 0.00% | +4,174+19.8% | 加碼 |
| Dynamic Technology Lab Private Ltd | 22,964 | $30.8 萬 | 0.07% | +12,612+121.8% | 加碼 |
| BNP Paribas Arbitrage, SA | 22,383 | $30.0 萬 | 0.00% | +7,063+46.1% | 加碼 |
| Arizona State Retirement System | 22,242 | $29.8 萬 | 0.00% | +4,375+24.5% | 加碼 |
| Profund Advisors LLC | 21,989 | $29.4 萬 | 0.01% | +3,323+17.8% | 加碼 |
| ProShare Advisors LLC | 21,539 | $28.8 萬 | 0.00% | +5,947+38.1% | 加碼 |