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Definium Therapeutics, Inc.

DFTX
Exchange
Nasdaq
Industry
Medicinal Chemicals & Botanical Products
SEC CIK
0001813814

In the last 90 days, Definium Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 362 institutions reported holding it in 13F filings for Q2 2026, worth $5.35B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Definium Therapeutics, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
362
+119 vs. Q1 2026
Shares held
114.8M
+40.3M (+54.1%) vs. Q1 2026
Total value
$5.35B
+$3.94B (+280.1%) vs. Q1 2026
New holders
148
117 more added
Sold out
29
64 more reduced

5 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DFTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 362 institutions
Q1 2021: 8 institutionsQ2 2021: 156 institutionsQ3 2021: 175 institutionsQ4 2021: 176 institutionsQ1 2022: 159 institutionsQ2 2022: 156 institutionsQ3 2022: 101 institutionsQ4 2022: 104 institutionsQ1 2023: 89 institutionsQ2 2023: 84 institutionsQ3 2023: 93 institutionsQ4 2023: 104 institutionsQ1 2024: 135 institutionsQ2 2024: 152 institutionsQ3 2024: 158 institutionsQ4 2024: 174 institutionsQ1 2025: 191 institutionsQ2 2025: 183 institutionsQ3 2025: 196 institutionsQ4 2025: 209 institutionsQ1 2026: 248 institutionsQ2 2026: 362 institutions
Value heldQ2 2026: $5.35B
Q1 2021: $932.0KQ2 2021: $131.0MQ3 2021: $104.8MQ4 2021: $72.0MQ1 2022: $53.6MQ2 2022: $15.1MQ3 2022: $20.5MQ4 2022: $11.1MQ1 2023: $12.6MQ2 2023: $13.9MQ3 2023: $12.1MQ4 2023: $17.9MQ1 2024: $327.2MQ2 2024: $299.3MQ3 2024: $281.6MQ4 2024: $288.9MQ1 2025: $240.5MQ2 2025: $271.0MQ3 2025: $468.6MQ4 2025: $908.7MQ1 2026: $1.47BQ2 2026: $5.35B
Institutions holding DFTX and their total value by quarter
QuarterHoldersValue
Q2 2026362$5.35B
Q1 2026248$1.47B
Q4 2025209$908.7M
Q3 2025196$468.6M
Q2 2025183$271.0M
Q1 2025191$240.5M
Q4 2024174$288.9M
Q3 2024158$281.6M
Q2 2024152$299.3M
Q1 2024135$327.2M
Q4 2023104$17.9M
Q3 202393$12.1M
Q2 202384$13.9M
Q1 202389$12.6M
Q4 2022104$11.1M
Q3 2022101$20.5M
Q2 2022156$15.1M
Q1 2022159$53.6M
Q4 2021176$72.0M
Q3 2021175$104.8M
Q2 2021156$131.0M
Q1 20218$932.0K

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Definium Therapeutics, Inc.; share changes are against Q1 2026.

Institutions holding DFTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
TSFG, LLC6$00.00%00.0%Unchanged
Huntington National Bank1$10.00%00.0%Unchanged
Quarry LP1$470.00%+1New
SJS Investment Consulting Inc.4$1890.00%+4New
Gilpin Wealth Management, LLC6$2830.00%+6New
Keating Financial Advisory Services, Inc.8$3760.00%+7+700.0%Added
Comprehensive Financial Planning, Inc.8$3760.00%+8New
Ares Financial Consulting, LLC8$3760.00%+8New
CNB Bank10$4700.00%+10New
Clearstead Advisors, LLC14$6600.00%+14New
Hilton Head Capital Partners, LLC20$9410.00%+20New
Covestor Ltd27$1.00K0.00%+27New
Rachor Investment Advisory Services, LLC25$1.18K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.25$1.18K0.00%00.0%Unchanged
Vanguard National Trust Co27$1.27K0.00%00.0%Unchanged
Robbins Farley LLC28$1.32K0.00%00.0%Unchanged
Benson Wealth Management INC30$1.41K0.00%00.0%Unchanged
Chesapeake Asset Management LLC33$1.55K0.00%00.0%Unchanged
Financial Gravity Companies, Inc.35$1.65K0.00%+35New
Plante Moran Financial Advisors, LLC36$1.69K0.00%00.0%Unchanged
Signaturefd, LLC40$1.88K0.00%+40New
TD Private Client Wealth LLC43$2.02K0.00%+43New
Institute for Wealth Management, LLC.46$2.16K0.00%+46New
HighMark Wealth Management LLC50$2.35K0.00%−50−50.0%Reduced
Essential Partners LLC60$2.82K0.00%+39+185.7%Added
MH & Associates Securities Management Corp66$3.10K0.00%00.0%Unchanged
Activest Wealth Management66$3.10K0.00%00.0%Unchanged
McDonald Partners LLC66$3.10K0.00%+66New
Global Retirement Partners, LLC66$3.10K0.00%+66New
Guardian Partners Inc.66$3.10K0.00%+66New
Versant Capital Management, Inc90$4.23K0.00%+90New
NBC Securities, Inc.100$4.70K0.00%00.0%Unchanged
Community Bank, N.A.135$6.35K0.00%+135New
Sankala Group LLC141$6.43K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co142$6.68K0.00%−13−8.4%Reduced
Salem Investment Counselors Inc150$7.06K0.00%00.0%Unchanged
Atlantic Edge Private Wealth Management, LLC193$9.08K0.00%00.0%Unchanged
Premier Financial Group193$9.08K0.00%+193New
Sims Investment Management, LLC199$9.36K0.00%+199New
Smartleaf Asset Management LLC215$10.0K0.00%00.0%Unchanged
Continuum Advisory, LLC213$10.0K0.00%+213New
Hollencrest Capital Management236$11.1K0.00%−7,150−96.8%Reduced
Ancora Advisors, LLC258$12.1K0.00%+7+2.8%Added
EverSource Wealth Advisors, LLC281$13.2K0.00%−14−4.7%Reduced
Neo Ivy Capital Management315$14.8K0.00%+315New
Aster Capital Management (DIFC) Ltd316$14.9K0.00%+316New
Harbour Investments, Inc.328$15.4K0.00%−228−41.0%Reduced
Western Pacific Wealth Management, LP333$15.7K0.01%00.0%Unchanged
Parallel Advisors, LLC333$15.7K0.00%+101+43.5%Added
NVWM, LLC416$19.6K0.00%00.0%Unchanged
Strategic Wealth Partners, Ltd.429$20.2K0.00%+263+158.4%Added
Sterling Capital Management LLC457$21.5K0.00%−1,986−81.3%Reduced
Larson Financial Group LLC541$25.4K0.00%+6+1.1%Added
Massmutual Trust Co FSB568$26.7K0.00%00.0%Unchanged
Los Angeles Capital Management LLC618$29.1K0.00%00.0%Unchanged
Optiver Holding B.V.624$29.4K0.00%+575+1,173.5%Added
Jones Financial Companies LLLP677$30.4K0.00%+497+276.1%Added
SBI Securities Co., Ltd.701$33.0K0.00%+603+615.3%Added
Atlantic Union Bankshares Corp776$36.5K0.00%+776New
SRS Capital Advisors, Inc.793$37.3K0.00%+327+70.2%Added
Bullock Wealth Management Group907$39.4K0.02%00.0%Unchanged
Nykredit A/S947$44.5K0.00%+947New
First Horizon Corp966$45.4K0.00%+4+0.4%Added
Rothschild Investment LLC999$47.0K0.00%+707+242.1%Added
Stone House Investment Management, LLC1,000$47.0K0.01%00.0%Unchanged
Kemnay Advisory Services Inc.1,135$53.4K0.01%+329+40.8%Added
Farther Finance Advisors, LLC1,162$54.7K0.00%+595+104.9%Added
GAMMA Investing LLC1,212$57.0K0.00%+101+9.1%Added
National Bank of Canada1,265$59.4K0.00%−443−25.9%Reduced
US Bancorp1,283$60.4K0.00%+1,283New
Penserra Capital Management LLC1,370$64.0K0.00%+1,370New
High Note Wealth, LLC1,600$75.3K0.01%+100+6.7%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,711$80.5K0.00%−101−5.6%Reduced
Crewe Advisors LLC1,999$94.0K0.01%00.0%Unchanged
GF Fund Management Co. Ltd.2,111$99.3K0.00%−102−4.6%Reduced
Caitong International Asset Management Co., Ltd2,201$103.5K0.01%−1,835−45.5%Reduced
Allworth Financial LP2,336$109.9K0.00%+2,209+1,739.4%Added
Strategic Investment Advisors2,345$110.3K0.01%+2,345New
Fifth Third Bancorp3,300$155.2K0.00%00.0%Unchanged
KBC Group NV3,310$156.0K0.00%+1,138+52.4%Added
Gotham Asset Management, LLC4,412$207.5K0.00%+4,412New
DnB Asset Management AS4,480$210.7K0.00%+4,480New
Oppenheimer & Co Inc4,490$211.2K0.00%+4,490New
Lewis Asset Management, LLC4,585$215.7K0.08%+4,585New
GWM Advisors LLC4,721$222.1K0.00%+4,714+67,342.9%Added
Endowment Wealth Management, Inc.4,793$225.5K0.09%+4,793New
Confluence Wealth Services, Inc.4,796$225.6K0.01%+4,796New
Mirae Asset Global Investments Co., Ltd.4,878$229.5K0.00%−322−6.2%Reduced
Jain Global LLC4,983$234.4K0.00%+4,983New
State Board of Administration of Florida Retirement System5,006$235.5K0.00%+5,006New
Winton Group Ltd5,100$239.9K0.01%+5,100New
F/M Investments LLC5,139$241.7K0.01%+5,139New
New Republic Capital, LLC5,175$243.4K0.06%+5,175New
Audent Global Asset Management, LLC5,200$244.6K0.27%+5,200New
Cambridge Investment Research Advisors, Inc.5,267$248.0K0.00%+5,267New
Swiss Life Asset Management Ltd5,637$265.2K0.00%−12,108−68.2%Reduced
JustInvest LLC5,649$265.7K0.00%+5,649New
MAI Capital Management5,686$267.5K0.00%+5,583+5,420.4%Added
Regal Investment Advisors LLC5,709$268.6K0.01%+5,709New
49 Wealth Management, LLC5,772$271.5K0.05%+5,772New