Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 136
- +16 vs. Q4 2024
- Shares held
- 73.9M
- +24.1M (+48.4%) vs. Q4 2024
- Total value
- $261.6M
- +$73.3M (+39.0%) vs. Q4 2024
- New holders
- 32
- 50 more added
- Sold out
- 16
- 31 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 1 | $4 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 25 | $89 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 53 | $188 | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 55 | $195 | 0.00% | 00.0% | Unchanged |
| Catherine Avery Investment Management LLC | 87 | $308 | 0.00% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 90 | $319 | 0.00% | 00.0% | Unchanged |
| Coldstream Capital Management Inc | 238 | $843 | 0.00% | +238 | New |
| UMA Financial Services, Inc. | 274 | $970 | 0.00% | +274 | New |
| Daiwa Securities Group Inc. | 266 | $1.00K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 285 | $1.01K | 0.00% | −210−42.4% | Reduced |
| Wells Fargo & Company | 300 | $1.06K | 0.00% | 00.0% | Unchanged |
| North Capital, Inc. | 500 | $1.77K | 0.00% | +500 | New |
| Dunhill Financial, LLC | 600 | $2.12K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 890 | $3.00K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 1,363 | $4.83K | 0.00% | +214+18.6% | Added |
| GF Fund Management Co. Ltd. | 1,700 | $6.02K | 0.00% | +261+18.1% | Added |
| Steward Partners Investment Advisory, LLC | 2,000 | $7.08K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 2,229 | $7.89K | 0.01% | +2,229 | New |
| Advisors Asset Management, Inc. | 2,573 | $9.11K | 0.00% | −1,329−34.1% | Reduced |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $9.12K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,930 | $10.7K | 0.00% | +646+28.3% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3,152 | $11.2K | 0.00% | +3,152 | New |
| Simplex Trading, LLC | 4,162 | $14.0K | 0.00% | −13,657−76.6% | Reduced |
| US Bancorp | 4,000 | $14.2K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 5,047 | $17.9K | 0.00% | +251+5.2% | Added |
| Russell Investments Group, Ltd. | 6,700 | $23.7K | 0.00% | +1,631+32.2% | Added |
| Tower Research Capital LLC (TRC) | 6,803 | $24.1K | 0.00% | −39,184−85.2% | Reduced |
| Valeo Financial Advisors, LLC | 10,000 | $35.4K | 0.00% | +10,000 | New |
| Hudson Bay Capital Management LP | 10,340 | $36.6K | 0.00% | +10,340 | New |
| EntryPoint Capital, LLC | 10,587 | $37.5K | 0.02% | −3,322−23.9% | Reduced |
| Capula Management Ltd | 10,980 | $38.9K | 0.00% | +10,980 | New |
| Brevan Howard Capital Management LP | 11,330 | $40.1K | 0.00% | +11,330 | New |
| Royal Bank of Canada | 11,850 | $42.0K | 0.00% | −24−0.2% | Reduced |
| Quadrature Capital Ltd | 12,744 | $45.0K | 0.00% | +12,744 | New |
| R Squared Ltd | 12,736 | $45.1K | 0.05% | +6,366+99.9% | Added |
| Ameriprise Financial Inc | 12,805 | $45.3K | 0.00% | −37,623−74.6% | Reduced |
| Two Sigma Securities, LLC | 13,301 | $47.1K | 0.01% | +13,301 | New |
| Engineers Gate Manager LP | 13,382 | $47.4K | 0.00% | −4,255−24.1% | Reduced |
| HSBC Holdings PLC | 14,419 | $51.4K | 0.00% | +2,853+24.7% | Added |
| Catalyst Funds Management Pty Ltd | 14,905 | $52.8K | 0.01% | +14,905 | New |
| Prudential Financial Inc | 15,200 | $53.8K | 0.00% | −4,200−21.6% | Reduced |
| State of Wyoming | 15,920 | $56.4K | 0.01% | −157−1.0% | Reduced |
| Capstone Investment Advisors, LLC | 16,150 | $57.2K | 0.00% | +16,150 | New |
| China Universal Asset Management Co., Ltd. | 17,188 | $60.8K | 0.01% | +2,653+18.3% | Added |
| Brown Advisory Inc | 19,930 | $70.6K | 0.00% | 00.0% | Unchanged |
| Marex Group plc | 20,000 | $70.8K | 0.00% | 00.0% | Unchanged |
| Premier Path Wealth Partners, LLC | 20,265 | $71.7K | 0.01% | +20,265 | New |
| Parsons Capital Management Inc | 21,645 | $76.6K | 0.00% | 00.0% | Unchanged |
| JustInvest LLC | 21,756 | $77.0K | 0.00% | +4,032+22.7% | Added |
| Paloma Partners Management Co | 22,242 | $78.7K | 0.01% | +22,242 | New |
| Gsa Capital Partners LLP | 23,085 | $82.0K | 0.01% | +12,446+117.0% | Added |
| Verition Fund Management LLC | 24,013 | $85.0K | 0.00% | +24,013 | New |
| SG Americas Securities, LLC | 25,210 | $89.0K | 0.00% | +9,252+58.0% | Added |
| Cannon Global Investment Management, LLC | 25,500 | $90.3K | 0.25% | +25,500 | New |
| Centiva Capital, LP | 28,222 | $99.9K | 0.01% | −5,609−16.6% | Reduced |
| Tudor Investment Corp Et Al | 33,428 | $118.3K | 0.00% | −259−0.8% | Reduced |
| Guggenheim Capital LLC | 37,796 | $133.8K | 0.00% | +1,928+5.4% | Added |
| XTX Topco Ltd | 39,542 | $140.0K | 0.01% | −13,834−25.9% | Reduced |
| Quantessence Capital LLC | 40,134 | $142.1K | 0.04% | +40,134 | New |
| Point72 Asia (Singapore) Pte. Ltd. | 43,200 | $152.9K | 0.04% | −29,663−40.7% | Reduced |
| LMR Partners LLP | 43,228 | $153.0K | 0.00% | +43,228 | New |
| Group One Trading, L.P. | 43,234 | $153.0K | 0.01% | −6,665−13.4% | Reduced |
| Invesco Ltd. | 45,694 | $161.8K | 0.00% | +45,694 | New |
| Jefferies Financial Group Inc. | 46,200 | $163.5K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 50,906 | $180.2K | 0.00% | +367+0.7% | Added |
| JPMorgan Chase & Co | 54,069 | $191.4K | 0.00% | −1,537−2.8% | Reduced |
| Algert Global LLC | 57,133 | $202.3K | 0.01% | +57,133 | New |
| Price T Rowe Associates Inc | 57,700 | $205.0K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 59,491 | $211.0K | 0.00% | −46,746−44.0% | Reduced |
| Alps Advisors Inc | 67,597 | $239.3K | 0.00% | +12,167+22.0% | Added |
| Jain Global LLC | 73,942 | $261.8K | 0.01% | +73,942 | New |
| Squarepoint Ops LLC | 75,849 | $268.5K | 0.00% | +565+0.8% | Added |
| Jacobs Levy Equity Management, Inc | 77,091 | $272.9K | 0.00% | −237,848−75.5% | Reduced |
| Cubist Systematic Strategies, LLC | 83,130 | $294.3K | 0.00% | −389,267−82.4% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 83,236 | $294.7K | 0.01% | −7,383−8.1% | Reduced |
| Man Group plc | 87,352 | $309.2K | 0.00% | −12,707−12.7% | Reduced |
| Tang Capital Management LLC | 100,000 | $354.0K | 0.02% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 100,000 | $354.0K | 0.01% | +100,000 | New |
| American Century Companies Inc | 107,014 | $378.8K | 0.00% | +47,704+80.4% | Added |
| Schonfeld Strategic Advisors LLC | 117,140 | $414.7K | 0.00% | −76,791−39.6% | Reduced |
| Dimensional Fund Advisors LP | 123,576 | $438.3K | 0.00% | +69,462+128.4% | Added |
| HRT Financial LP | 127,998 | $453.0K | 0.00% | +127,998 | New |
| Barclays PLC | 137,405 | $486.4K | 0.00% | +62,560+83.6% | Added |
| Northern Trust Corp | 139,332 | $493.2K | 0.00% | +32,768+30.7% | Added |
| Bank of Montreal | 143,512 | $508.0K | 0.00% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 148,559 | $525.9K | 0.00% | +98,311+195.7% | Added |
| Bridgeway Capital Management, LLC | 155,700 | $551.2K | 0.01% | +9,200+6.3% | Added |
| Omers Administration Corp | 169,600 | $600.4K | 0.01% | +103,600+157.0% | Added |
| Falcon Edge Capital, LP | 187,311 | $663.1K | 0.30% | +38,684+26.0% | Added |
| Kennondale Capital Management LLC | 202,743 | $717.7K | 0.78% | +68,298+50.8% | Added |
| Federated Hermes, Inc. | 202,785 | $717.9K | 0.00% | +469+0.2% | Added |
| Acadian Asset Management LLC | 242,107 | $855.0K | 0.00% | −369,819−60.4% | Reduced |
| Marshall Wace, LLP | 247,275 | $875.4K | 0.00% | +62,597+33.9% | Added |
| Walleye Capital LLC | 250,888 | $888.1K | 0.01% | −267,896−51.6% | Reduced |
| Aldebaran Capital, LLC | 259,253 | $917.8K | 0.87% | −3,500−1.3% | Reduced |
| State Street Corp | 261,783 | $926.7K | 0.00% | +43,400+19.9% | Added |
| Allostery Investments LP | 266,099 | $942.0K | 1.36% | +266,099 | New |
| D. E. Shaw & Co., Inc. | 270,006 | $955.8K | 0.00% | −36,738−12.0% | Reduced |
| Wellington Management Group LLP | 290,682 | $1.03M | 0.00% | +80,974+38.6% | Added |
| Jane Street Group, LLC | 331,185 | $1.17M | 0.00% | −434,290−56.7% | Reduced |