Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2024
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 143
- −35 vs. Q4 2023
- Shares held
- 49.5M
- −10.8M (−17.9%) vs. Q4 2023
- Total value
- $141.5M
- −$745.9M (−84.1%) vs. Q4 2023
- New holders
- 25
- 56 more added
- Sold out
- 60
- 48 more reduced
Compare with Q4 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2024
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 5,348,139 | $15.2M | 0.00% | +72,573+1.4% | Added |
| BlackRock Inc. | 4,474,722 | $12.7M | 0.00% | +472,388+11.8% | Added |
| Goldman Sachs Group Inc | 2,943,186 | $8.36M | 0.00% | +1,686,325+134.2% | Added |
| Millennium Management LLC | 2,471,455 | $7.02M | 0.01% | +198,812+8.7% | Added |
| Morgan Stanley | 2,070,653 | $5.88M | 0.00% | −759,590−26.8% | Reduced |
| State Street Corp | 2,060,042 | $5.85M | 0.00% | +618,640+42.9% | Added |
| Franklin Resources Inc | 1,855,886 | $5.27M | 0.00% | +530,885+40.1% | Added |
| Boxer Capital, LLC | 1,500,000 | $4.26M | 0.21% | +1,500,000 | New |
| Two Sigma Investments, LP | 1,432,865 | $4.07M | 0.01% | +1,389,065+3,171.4% | Added |
| Citadel Advisors LLC | 1,330,384 | $3.78M | 0.00% | −910,501−40.6% | Reduced |
| Farallon Capital Management, L.L.C. | 1,150,221 | $3.27M | 0.02% | +1,150,221 | New |
| Geode Capital Management, LLC | 1,066,245 | $3.03M | 0.00% | +35,529+3.4% | Added |
| D. E. Shaw & Co., Inc. | 1,042,583 | $2.96M | 0.00% | +495,618+90.6% | Added |
| Jane Street Group, LLC | 1,027,620 | $2.92M | 0.00% | −129,545−11.2% | Reduced |
| Rock Springs Capital Management LP | 1,011,412 | $2.87M | 0.07% | +476,400+89.0% | Added |
| Alyeska Investment Group, L.P. | 1,008,607 | $2.86M | 0.02% | +1,008,607 | New |
| Price T Rowe Associates Inc | 970,555 | $2.76M | 0.00% | +75,775+8.5% | Added |
| Qube Research & Technologies Ltd | 944,063 | $2.68M | 0.00% | +461,464+95.6% | Added |
| Citigroup Inc | 914,727 | $2.60M | 0.00% | +527,063+136.0% | Added |
| Two Sigma Advisers, LP | 798,900 | $2.27M | 0.01% | +798,900 | New |
| Deutsche Bank AG | 756,169 | $2.15M | 0.00% | −96,831−11.4% | Reduced |
| Renaissance Technologies LLC | 704,600 | $2.00M | 0.00% | +633,312+888.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 526,688 | $1.50M | 0.01% | +270,082+105.3% | Added |
| Graham Capital Management, L.P. | 524,627 | $1.49M | 0.04% | +524,627 | New |
| Woodline Partners LP | 523,772 | $1.49M | 0.01% | +52,971+11.3% | Added |
| Silverarc Capital Management, LLC | 500,000 | $1.42M | 0.40% | +500,000 | New |
| Hudson Bay Capital Management LP | 498,000 | $1.41M | 0.01% | +37,400+8.1% | Added |
| Charles Schwab Investment Management Inc | 435,903 | $1.24M | 0.00% | +48,283+12.5% | Added |
| Northern Trust Corp | 425,567 | $1.21M | 0.00% | −9,870−2.3% | Reduced |
| JPMorgan Chase & Co | 409,759 | $1.16M | 0.00% | +337,871+470.0% | Added |
| American Century Companies Inc | 378,798 | $1.08M | 0.00% | −163,748−30.2% | Reduced |
| Walleye Capital LLC | 361,870 | $1.03M | 0.01% | −220,858−37.9% | Reduced |
| State of Wisconsin Investment Board | 361,722 | $1.03M | 0.00% | +333,268+1,171.3% | Added |
| Y-Intercept (Hong Kong) Ltd | 341,517 | $969.9K | 0.07% | +292,313+594.1% | Added |
| Ikarian Capital, LLC | 331,451 | $941.3K | 0.26% | −546,049−62.2% | Reduced |
| Sofinnova Investments, Inc. | 306,729 | $871.1K | 0.05% | +306,729 | New |
| Perceptive Advisors LLC | 300,000 | $852.0K | 0.02% | −1,569,125−83.9% | Reduced |
| Sherbrooke Park Advisers LLC | 299,452 | $850.4K | 0.17% | +299,452 | New |
| Bank of America Corp | 275,956 | $783.7K | 0.00% | +155,628+129.3% | Added |
| Sphera Funds Management Ltd. | 267,250 | $759.0K | 0.12% | +83,600+45.5% | Added |
| Susquehanna International Group, LLP | 246,799 | $700.9K | 0.00% | −316,141−56.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 23,842 | $671.7K | 0.00% | −515−2.1% | Reduced |
| Group One Trading, L.P. | 222,722 | $632.5K | 0.02% | −280,950−55.8% | Reduced |
| UBS Group AG | 210,573 | $598.0K | 0.00% | +171,559+439.7% | Added |
| Bank of New York Mellon Corp | 198,029 | $562.4K | 0.00% | +7,029+3.7% | Added |
| Atom Investors LP | 189,796 | $539.0K | 0.07% | +189,796 | New |
| Panagora Asset Management Inc | 189,016 | $536.8K | 0.00% | +189,016 | New |
| Cubist Systematic Strategies, LLC | 176,114 | $500.2K | 0.01% | −260,721−59.7% | Reduced |
| Federated Hermes, Inc. | 175,983 | $499.8K | 0.00% | +73,483+71.7% | Added |
| First Trust Advisors LP | 170,478 | $484.2K | 0.00% | +153,098+880.9% | Added |
| Point72 Asset Management, L.P. | 170,000 | $482.8K | 0.00% | −2,581,305−93.8% | Reduced |
| PDT Partners, LLC | 166,896 | $474.0K | 0.04% | +107,929+183.0% | Added |
| Squarepoint Ops LLC | 159,309 | $452.4K | 0.00% | +125,859+376.3% | Added |
| Aviva PLC | 145,418 | $413.0K | 0.00% | +145,418 | New |
| Alps Advisors Inc | 139,250 | $395.5K | 0.00% | +89,522+180.0% | Added |
| Nuveen Asset Management, LLC | 137,973 | $391.8K | 0.00% | −883,684−86.5% | Reduced |
| TD Asset Management Inc | 131,200 | $372.6K | 0.00% | +16,200+14.1% | Added |
| Winton Group Ltd | 119,676 | $339.9K | 0.02% | +119,676 | New |
| Standard Life Aberdeen plc | 118,247 | $335.8K | 0.00% | −77,246−39.5% | Reduced |
| AQR Capital Management LLC | 116,489 | $330.8K | 0.00% | +93,145+399.0% | Added |
| Hennion & Walsh Asset Management, Inc. | 112,867 | $320.5K | 0.02% | +27,937+32.9% | Added |
| Barclays PLC | 106,842 | $303.4K | 0.00% | +15,963+17.6% | Added |
| Boothbay Fund Management, LLC | 102,777 | $291.9K | 0.01% | −116,564−53.1% | Reduced |
| Tang Capital Management LLC | 100,000 | $284.0K | 0.03% | −100,000−50.0% | Reduced |
| Manufacturers Life Insurance Company, The | 95,570 | $271.4K | 0.00% | +9,922+11.6% | Added |
| Swiss National Bank | 86,600 | $245.9K | 0.00% | +6,900+8.7% | Added |
| State Board of Administration of Florida Retirement System | 8,310 | $243.8K | 0.00% | −6,270−43.0% | Reduced |
| Simplex Trading, LLC | 82,107 | $233.0K | 0.01% | −47,315−36.6% | Reduced |
| Capstone Investment Advisors, LLC | 80,084 | $227.4K | 0.00% | +60,084+300.4% | Added |
| Gsa Capital Partners LLP | 79,652 | $226.0K | 0.02% | −52,525−39.7% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 73,130 | $207.7K | 0.00% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 72,572 | $206.1K | 0.00% | +72,572 | New |
| Rhumbline Advisers | 69,403 | $197.1K | 0.00% | +1,120+1.6% | Added |
| Profund Advisors LLC | 64,969 | $184.5K | 0.01% | +40,362+164.0% | Added |
| Man Group plc | 60,679 | $172.3K | 0.00% | +60,679 | New |
| Rafferty Asset Management, LLC | 53,201 | $151.1K | 0.00% | +34,881+190.4% | Added |
| Alliancebernstein L.P. | 51,542 | $146.4K | 0.00% | 00.0% | Unchanged |
| Legacy Advisors, LLC | 50,000 | $142.0K | 0.02% | 00.0% | Unchanged |
| Mariner, LLC | 49,268 | $139.9K | 0.00% | −163−0.3% | Reduced |
| Point72 (DIFC) Ltd | 48,993 | $139.1K | 0.01% | +48,993 | New |
| HSBC Holdings PLC | 48,307 | $137.2K | 0.00% | +48,307 | New |
| California State Teachers Retirement System | 44,561 | $126.6K | 0.00% | +173+0.4% | Added |
| ADAR1 Capital Management, LLC | 38,858 | $110.4K | 0.03% | −38,700−49.9% | Reduced |
| Credit Suisse AG | 36,643 | $104.1K | 0.00% | −1,409−3.7% | Reduced |
| Wellington Management Group LLP | 33,933 | $96.4K | 0.00% | −10,820−24.2% | Reduced |
| Twinbeech Capital LP | 33,604 | $95.4K | 0.00% | −132,840−79.8% | Reduced |
| Legal & General Group Plc | 32,854 | $93.3K | 0.00% | −6,812−17.2% | Reduced |
| GTS Securities LLC | 29,403 | $83.5K | 0.00% | +3,092+11.8% | Added |
| SG Americas Securities, LLC | 26,139 | $74.0K | 0.00% | −39,900−60.4% | Reduced |
| Virtus ETF Advisers LLC | 25,849 | $73.4K | 0.04% | +3,719+16.8% | Added |
| American International Group, Inc. | 25,031 | $71.1K | 0.00% | −215−0.9% | Reduced |
| Maven Securities LTD | 25,000 | $71.0K | 0.00% | +25,000 | New |
| Invesco Ltd. | 24,349 | $69.2K | 0.00% | +454+1.9% | Added |
| Parsons Capital Management Inc | 21,945 | $62.3K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 21,376 | $60.7K | 0.00% | +21,376 | New |
| New York State Common Retirement Fund | 21,244 | $60.3K | 0.00% | −2,510−10.6% | Reduced |
| Wells Fargo & Company | 20,949 | $59.5K | 0.00% | −13,316−38.9% | Reduced |
| Premier Path Wealth Partners, LLC | 20,265 | $57.6K | 0.01% | 00.0% | Unchanged |
| Brown Advisory Inc | 19,961 | $56.7K | 0.00% | +6,500+48.3% | Added |
| UBS Asset Management Americas Inc | 19,700 | $55.9K | 0.00% | 00.0% | Unchanged |