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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
143
−35 vs. Q4 2023
Shares held
49.5M
−10.8M (−17.9%) vs. Q4 2023
Total value
$141.5M
−$745.9M (−84.1%) vs. Q4 2023
New holders
25
56 more added
Sold out
60
48 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 143 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ1 2024: $141.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding AMLX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC19,390$55.1K0.00%−1,416,761−98.6%Reduced
Two Sigma Securities, LLC18,141$51.5K0.00%+18,141New
Voya Investment Management LLC17,357$49.3K0.00%−2,818−14.0%Reduced
Guggenheim Capital LLC16,338$46.4K0.00%+1,392+9.3%Added
STRS Ohio16,500$46.0K0.00%−1,000−5.7%Reduced
Allspring Global Investments Holdings, LLC15,276$43.4K0.00%+15,247+52,575.9%Added
Handelsbanken Fonder AB14,700$42.0K0.00%+2,800+23.5%Added
Janus Henderson Group PLC14,717$41.9K0.00%−36−0.2%Reduced
Principal Financial Group Inc14,666$41.7K0.00%+194+1.3%Added
CWM, LLC14,030$40.0K0.00%+827+6.3%Added
ProShare Advisors LLC13,874$39.4K0.00%+1,153+9.1%Added
MetLife Investment Management13,768$39.1K0.00%−12,944−48.5%Reduced
Victory Capital Management Inc13,514$38.4K0.00%+13,514New
Teza Capital Management LLC13,431$38.1K0.01%−1,229−8.4%Reduced
China Universal Asset Management Co., Ltd.13,004$36.9K0.00%+5,189+66.4%Added
Tudor Investment Corp Et Al12,753$36.2K0.00%−20,899−62.1%Reduced
Arizona State Retirement System12,061$34.3K0.00%+759+6.7%Added
Wolverine Trading, LLC11,571$32.9K0.00%+11,571New
Cipher Capital LP10,717$30.4K0.01%+10,717New
Tower Research Capital LLC (TRC)10,296$29.2K0.00%−2,018−16.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,022$28.5K0.00%−367−3.5%Reduced
Primecap Management Co10,000$28.4K0.00%−146,900−93.6%Reduced
Advisors Asset Management, Inc.8,350$23.7K0.00%−273−3.2%Reduced
Banque Cantonale Vaudoise5,900$17.0K0.00%+5,900New
Ameritas Investment Partners, Inc.5,046$14.3K0.00%00.0%Unchanged
Quarry LP3,000$8.52K0.00%+2,250+300.0%Added
Metropolitan Life Insurance Co2,899$8.23K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC2,000$5.68K0.00%00.0%Unchanged
Amalgamated Bank1,726$5.00K0.00%−5,478−76.0%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$3.57K0.00%00.0%Unchanged
Royal Bank of Canada1,352$3.00K0.00%−14,803−91.6%Reduced
Cutler Group LP1,000$2.00K0.00%+100+11.1%Added
Advisor Group Holdings, Inc.389$1.10K0.00%−2,761−87.7%Reduced
Daiwa Securities Group Inc.266$1.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.214$6080.00%+18+9.2%Added
Fernwood Investment Management, LLC200$5680.00%+200New
Russell Investments Group, Ltd.162$4600.00%−2,675−94.3%Reduced
Salem Investment Counselors Inc55$1570.00%00.0%Unchanged
GAMMA Investing LLC35$990.00%00.0%Unchanged
Kelly Financial Services LLC33$940.00%00.0%Unchanged
Nisa Investment Advisors, LLC10$280.00%−24−70.6%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC10$280.00%+10New
Covestor Ltd74$00.00%−3,652−98.0%Reduced
Viking Global Investors LPSuperinvestorViking Global Investors0$00.00%−2,962,555−100.0%Sold out
Stonepine Capital Management, LLC0$00.00%−2,500,000−100.0%Sold out
Eventide Asset Management, LLC0$00.00%−1,116,837−100.0%Sold out
Saturn V Capital Management LLC0$00.00%−1,099,268−100.0%Sold out
Jupiter Asset Management Ltd0$00.00%−1,060,900−100.0%Sold out
Marshall Wace, LLP0$00.00%−985,114−100.0%Sold out
Falcon Edge Capital, LP0$00.00%−846,240−100.0%Sold out
Emerald Advisers, LLC0$00.00%−802,610−100.0%Sold out
GMT Capital Corp0$00.00%−786,000−100.0%Sold out
Emerald Mutual Fund Advisers Trust0$00.00%−656,530−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−620,110−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−465,445−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−312,463−100.0%Sold out
Schroder Investment Management Group0$00.00%−295,000−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−275,773−100.0%Sold out
Trexquant Investment LP0$00.00%−265,046−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−242,300−100.0%Sold out
AlphaCentric Advisors LLC0$00.00%−151,000−100.0%Sold out
Algert Global LLC0$00.00%−147,020−100.0%Sold out
DAFNA Capital Management LLC0$00.00%−122,547−100.0%Sold out
Altium Capital Management LP0$00.00%−119,526−100.0%Sold out
Norges Bank0$00.00%−116,400−100.0%Sold out
Phocas Financial Corp.0$00.00%−86,073−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−84,055−100.0%Sold out
StemPoint Capital LP0$00.00%−83,381−100.0%Sold out
DekaBank Deutsche Girozentrale0$00.00%−83,000−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−72,824−100.0%Sold out
Seven Eight Capital, LP0$00.00%−66,801−100.0%Sold out
Avidity Partners Management LP0$00.00%−64,501−100.0%Sold out
Janney Montgomery Scott LLC0$00.00%−59,111−100.0%Sold out
Nebula Research & Development LLC0$00.00%−57,850−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−53,517−100.0%Sold out
Caption Management, LLC0$00.00%−47,000−100.0%Sold out
Cornercap Investment Counsel Inc0$00.00%−44,487−100.0%Sold out
HRT Financial LP0$00.00%−42,192−100.0%Sold out
Walleye Trading LLC0$00.00%−35,774−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−33,689−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−31,342−100.0%Sold out
Engineers Gate Manager LP0$00.00%−29,205−100.0%Sold out
Virtu Financial LLC0$00.00%−27,715−100.0%Sold out
HighVista Strategies LLC0$00.00%−26,349−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−22,007−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−19,698−100.0%Sold out
Captrust Financial Advisors0$00.00%−19,561−100.0%Sold out
Centiva Capital, LP0$00.00%−19,188−100.0%Sold out
J. Goldman & Co LP0$00.00%−19,029−100.0%Sold out
XTX Topco Ltd0$00.00%−18,913−100.0%Sold out
Greenwood Capital Associates LLC0$00.00%−17,395−100.0%Sold out
Lion Point Capital, LP0$00.00%−14,000−100.0%Sold out
Jump Financial, LLC0$00.00%−13,343−100.0%Sold out
Belvedere Trading LLC0$00.00%−13,213−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−10,641−100.0%Sold out
Point72 Middle East FZE0$00.00%−9,141−100.0%Sold out
Quest Partners LLC0$00.00%−6,035−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−5,100−100.0%Sold out
Capital Advisors, Ltd. LLC0$00.00%−290−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−200−100.0%Sold out