Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
Open-market trades, last 90 days
Open-market purchases (P) and sales (S) by Amylyx Pharmaceuticals, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.
- Open-market buys
- 0 filings
- Open-market sells
- 6 filings
- 5 insiders, $3.48M in total
- Insiders trading
- 5
- Net value
- −$3.48M
- Purchases minus sales
Insider roster
Directors, officers and 10% owners who have filed a Form 4 for Amylyx Pharmaceuticals, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.
| Name | Title | Last reported holding | Last filing | Filings, past year |
|---|---|---|---|---|
| Bedrosian Camille L | Chief Medical Officer | 278,064 | Sep 14, 2026 | 6 |
| Frates James M | Chief Financial Officer | 233,625 | Sep 14, 2026 | 7 |
| Mazzariello Gina | Chief Legal Officer | 190,838 | Sep 14, 2026 | 8 |
| Klee Justin B. | Co-Chief Executive Officer | 3,613,056 | Sep 14, 2026 | 8 |
| Cohen Joshua B | Co-Chief Executive Officer | 3,613,123 | Sep 14, 2026 | 8 |
| Firestone Karen | Director | 116,900 | Sep 2, 2026 | 4 |
| Milne George M Jr | Director | 812,881 | Jun 8, 2026 | 2 |
| Quimi Daphne | Director | 5,000 | Jun 8, 2026 | 1 |
| Fonteyne Paul R. | Director | 3,947 | Jun 8, 2026 | 1 |
| Zeiher Bernhardt G | Director | 10,000 | Jun 8, 2026 | 1 |
| Yeramian Patrick D | Chief Medical Officer | 205,605 | Jan 11, 2024 | 0 |
| Olinger Margaret | Chief Commercial Officer | 276,108 | Dec 29, 2023 | 0 |
| Morningside Venture Investments Ltd | 10% Owner | 4,997,302 | Aug 17, 2023 | 0 |
| Viking Global Investors LP | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Halvorsen Ole Andreas | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Ott David C. | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Viking Global Opportunities Portfolio GP LLC | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Viking Global Opportunities GP LLC | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Viking Global Opportunities Illiquid Investments Sub-Master LP | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Shabet Rose Sharon | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Viking Global Opportunities Parent GP LLC | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| Dragsa 96 LLC | 10% Owner | 1,850,940Indirect | Sep 9, 2022 | 0 |
| ALS Invest 1 B.V. | 10% Owner | 5,895,280 | Jul 8, 2022 | 0 |
| Cheng Isaac | Director | 6,578 | Jun 10, 2022 | 0 |
| Mvil, LLC | 10% Owner | 10,678,808Indirect | Mar 17, 2022 | 0 |
Insider trades
Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Sep 14, 2026 (view filing)4:00 PM ET | Sep 10 | 4 days | Bedrosian Camille LChief Medical Officer | SSale | −10.0K | $32.40 | −$324.9K | −3.5%278.1K after | 2 lots |
| Sep 14, 2026 (view filing)4:00 PM ET | Sep 10 | 4 days | Frates James MChief Financial Officer | SSale | −10.8K | $32.36 | −$349.8K | −4.4%233.6K after | 2 lots |
| Sep 14, 2026 (view filing)4:00 PM ET | Sep 10 | 4 days | Mazzariello GinaChief Legal Officer | SSale | −9.54K | $32.46 | −$309.5K | −4.8%190.8K after | 2 lots |
| Sep 14, 2026 (view filing)4:00 PM ET | Sep 10 | 4 days | Klee Justin B.Co-Chief Executive Officer | SSale | −30.5K | $32.18 | −$980.3K | −0.8%3.61M after | 2 lots |
| Sep 14, 2026 (view filing)4:00 PM ET | Sep 10 | 4 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −30.5K | $32.19 | −$980.5K | −0.8%3.61M after | 2 lots |
| Jul 13, 2026 (view filing)4:00 PM ET | Jul 9-10 | 4 days | Mazzariello GinaChief Legal Officer | SSale | −30.0K | $17.96 | −$538.9K | −14.3%179.1K after | 2 lots10b5-1 |
| May 26, 2026 (view filing) | May 21 | 5 days | Firestone KarenDirector | PPurchase | +3.80K | $13.51 | +$51.3K | +6.0%66.9K after | |
| Mar 4, 2026 (view filing) | Mar 2 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −29.3K | $14.47 | −$423.7K | −0.9%3.33M after | |
| Mar 4, 2026 (view filing) | Mar 2 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −29.3K | $14.48 | −$424.0K | −0.9%3.33M after | |
| Mar 4, 2026 (view filing) | Mar 2 | 2 days | Bedrosian Camille LChief Medical Officer | SSale | −6.46K | $14.58 | −$94.2K | −3.7%169.3K after | |
| Mar 4, 2026 (view filing) | Mar 2 | 2 days | Frates James MChief Financial Officer | SSale | −7.91K | $14.52 | −$114.8K | −4.6%165.6K after | |
| Mar 4, 2026 (view filing) | Mar 2 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −6.84K | $14.52 | −$99.4K | −4.8%134.4K after | |
| Feb 25, 2026 (view filing) | Feb 23 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −3.42K | $14.14 | −$48.3K | −2.4%141.3K after | |
| Feb 4, 2026 (view filing) | Feb 2 | 2 days | Frates James MChief Financial Officer | SSale | −3.56K | $14.65 | −$52.1K | −2.0%173.5K after | |
| Feb 4, 2026 (view filing) | Feb 2 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −15.5K | $14.68 | −$227.5K | −0.5%3.36M after | |
| Feb 4, 2026 (view filing) | Feb 2 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −3.45K | $14.65 | −$50.5K | −2.3%144.7K after | |
| Feb 4, 2026 (view filing) | Feb 2 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −15.5K | $14.69 | −$227.7K | −0.5%3.36M after | |
| Jan 20, 2026 (view filing) | Jan 15-16 | 5 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −138.2K | $13.59 | −$1.88M | −3.9%3.38M after | 2 lots |
| Jan 20, 2026 (view filing) | Jan 15-16 | 5 days | Klee Justin B.Co-Chief Executive Officer | SSale | −138.2K | $13.58 | −$1.88M | −3.9%3.38M after | 2 lots |
| Jan 8, 2026 (view filing) | Jan 6 | 2 days | Frates James MChief Financial Officer | SSale | −3.33K | $11.11 | −$37.0K | −1.8%177.1K after | |
| Jan 8, 2026 (view filing) | Jan 6 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −7.71K | $11.09 | −$85.6K | −0.2%3.32M after | |
| Jan 8, 2026 (view filing) | Jan 6 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −7.71K | $11.09 | −$85.6K | −0.2%3.32M after | |
| Dec 23, 2025 (view filing) | Dec 23 | Same day | Firestone KarenDirector | PPurchase | +8.10K | $12.45 | +$100.8K | +14.7%63.1K after | |
| Dec 3, 2025 (view filing) | Dec 1 | 2 days | Bedrosian Camille LChief Medical Officer | SSale | −6.58K | $14.35 | −$94.4K | −3.6%175.8K after | |
| Oct 2, 2025 (view filing) | Sep 30 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −30.0K | $14.37 | −$430.9K | −0.9%3.33M after | 2 lots |
| Oct 2, 2025 (view filing) | Sep 30 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −8.83K | $14.58 | −$128.7K | −5.6%148.1K after | |
| Oct 2, 2025 (view filing) | Sep 30 | 2 days | Frates James MChief Financial Officer | SSale | −10.6K | $14.65 | −$154.7K | −3.6%280.4K after | |
| Oct 2, 2025 (view filing) | Sep 30 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −29.9K | $14.34 | −$429.4K | −0.9%3.33M after | 2 lots |
| Oct 2, 2025 (view filing) | Sep 30 | 2 days | Bedrosian Camille LChief Medical Officer | SSale | −12.0K | $14.58 | −$175.5K | −6.2%182.3K after | |
| Aug 14, 2025 (view filing) | Aug 12-13 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −30.0K | $8.21 | −$246.2K | −16.0%157.0K after | 2 lots10b5-1 |
| Apr 2, 2025 (view filing) | Mar 31 | 2 days | Frates James MChief Financial Officer | SSale | −10.9K | $3.47 | −$37.8K | −3.6%291.0K after | |
| Apr 2, 2025 (view filing) | Mar 31 | 2 days | Bedrosian Camille LChief Medical Officer | SSale | −12.4K | $3.47 | −$43.1K | −6.0%194.4K after | |
| Apr 2, 2025 (view filing) | Mar 31 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −9.19K | $3.48 | −$32.0K | −4.7%188.0K after | |
| Apr 2, 2025 (view filing) | Mar 31 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −21.5K | $3.47 | −$74.6K | −0.6%3.36M after | |
| Apr 2, 2025 (view filing) | Mar 31 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −21.5K | $3.46 | −$74.4K | −0.6%3.36M after | |
| Mar 24, 2025 (view filing) | Mar 20 | 4 days | Zeiher Bernhardt GDirector | PPurchase | +10.0K | $3.70 | +$37.0K | New position10.0K after | |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −4.59K | $3.15 | −$14.5K | −0.1%3.20M after | |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −4.59K | $3.17 | −$14.6K | −0.1%3.20M after | |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −1.61K | $3.12 | −$5.03K | −1.2%133.3K after | |
| Feb 26, 2025 (view filing) | Feb 24 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −4.17K | $3.15 | −$13.1K | −3.0%134.9K after | |
| Feb 5, 2025 (view filing) | Feb 3 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −3.68K | $3.49 | −$12.8K | −2.6%139.1K after | |
| Feb 5, 2025 (view filing) | Feb 3 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −11.9K | $3.47 | −$41.1K | −0.4%3.20M after | |
| Feb 5, 2025 (view filing) | Feb 3 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −11.9K | $3.47 | −$41.1K | −0.4%3.16M after | |
| Jan 8, 2025 (view filing) | Jan 6 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −7.47K | $4.04 | −$30.2K | −0.2%3.18M after | |
| Jan 8, 2025 (view filing) | Jan 6 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −7.47K | $4.05 | −$30.3K | −0.2%3.21M after | |
| Dec 3, 2024 (view filing) | Dec 2 | 1 day | Bedrosian Camille LChief Medical Officer | SSale | −5.42K | $5.54 | −$30.0K | −3.8%138.4K after | |
| Oct 2, 2024 (view filing) | Sep 30 | 2 days | Klee Justin B.Co-Chief Executive Officer | SSale | −18.6K | $3.20 | −$59.5K | −0.6%3.12M after | |
| Oct 2, 2024 (view filing) | Sep 30 | 2 days | Cohen Joshua BCo-Chief Executive Officer | SSale | −18.6K | $3.20 | −$59.5K | −0.6%3.22M after | |
| Oct 2, 2024 (view filing) | Sep 30 | 2 days | Bedrosian Camille LChief Medical Officer | SSale | −11.4K | $3.20 | −$36.6K | −7.4%143.8K after | |
| Oct 2, 2024 (view filing) | Sep 30 | 2 days | Mazzariello GinaChief Legal Officer | SSale | −8.71K | $3.20 | −$27.9K | −5.7%142.8K after |