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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Open-market trades, last 90 days

Open-market purchases (P) and sales (S) by Amylyx Pharmaceuticals, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.

Open-market buys
0 filings
Open-market sells
6 filings
5 insiders, $3.48M in total
Insiders trading
5
Net value
−$3.48M
Purchases minus sales

Insider roster

Directors, officers and 10% owners who have filed a Form 4 for Amylyx Pharmaceuticals, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.

Insider roster for Amylyx Pharmaceuticals, Inc.
NameTitleLast reported holdingLast filingFilings, past year
Bedrosian Camille LChief Medical Officer278,064Sep 14, 20266
Frates James MChief Financial Officer233,625Sep 14, 20267
Mazzariello GinaChief Legal Officer190,838Sep 14, 20268
Klee Justin B.Co-Chief Executive Officer3,613,056Sep 14, 20268
Cohen Joshua BCo-Chief Executive Officer3,613,123Sep 14, 20268
Firestone KarenDirector116,900Sep 2, 20264
Milne George M JrDirector812,881Jun 8, 20262
Quimi DaphneDirector5,000Jun 8, 20261
Fonteyne Paul R.Director3,947Jun 8, 20261
Zeiher Bernhardt GDirector10,000Jun 8, 20261
Yeramian Patrick DChief Medical Officer205,605Jan 11, 20240
Olinger MargaretChief Commercial Officer276,108Dec 29, 20230
Morningside Venture Investments Ltd10% Owner4,997,302Aug 17, 20230
Viking Global Investors LP10% Owner1,850,940IndirectSep 9, 20220
Halvorsen Ole Andreas10% Owner1,850,940IndirectSep 9, 20220
Ott David C.10% Owner1,850,940IndirectSep 9, 20220
Viking Global Opportunities Portfolio GP LLC10% Owner1,850,940IndirectSep 9, 20220
Viking Global Opportunities GP LLC10% Owner1,850,940IndirectSep 9, 20220
Viking Global Opportunities Illiquid Investments Sub-Master LP10% Owner1,850,940IndirectSep 9, 20220
Shabet Rose Sharon10% Owner1,850,940IndirectSep 9, 20220
Viking Global Opportunities Parent GP LLC10% Owner1,850,940IndirectSep 9, 20220
Dragsa 96 LLC10% Owner1,850,940IndirectSep 9, 20220
ALS Invest 1 B.V.10% Owner5,895,280Jul 8, 20220
Cheng IsaacDirector6,578Jun 10, 20220
Mvil, LLC10% Owner10,678,808IndirectMar 17, 20220

Insider trades

Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 10, 2022 (view filing)Jan 64 daysOlinger MargaretChief Commercial OfficerPPurchase+6.84K$19.00+$130.0K+3.3%216.8K after
Jan 10, 2022 (view filing)Jan 64 daysMilne George M JrDirectorPPurchase+26.3K$19.00+$500.0K+13.5%221.4K after
Jan 10, 2022 (view filing)Jan 64 daysCheng IsaacDirectorPPurchase+6.58K$19.00+$125.0KNew position6.58K after
Jan 10, 2022 (view filing)Jan 64 daysFonteyne Paul R.DirectorPPurchase+3.95K$19.00+$75.0KNew position3.95K after
Jan 13, 2022 (view filing)9:05 PM ETJan 112 daysViking Global Investors LP and 7 others10% OwnerPPurchase+2.30M$19.00+$43.7MNew position2.30M after
Jan 25, 2022 (view filing)Jan 1114 daysLateMorningside Venture Investments Ltd10% OwnerPPurchase+263.2K$19.00+$5.00M+2.5%10.7M after
Mar 17, 2022 (view filing)5:14 PM ETJan 1165 daysMorningside Venture Investments Ltd and 1 other10% OwnerPPurchase+263.2K$19.00+$5.00M+2.5%10.7M afterAmendedDuplicate filing
Jul 8, 2022 (view filing)Jul 62 daysALS Invest 1 B.V.10% OwnerSSale−60.6K$20.70−$1.25M−1.0%5.90M after4 lots
Sep 9, 2022 (view filing)9:48 PM ETSep 8-91 dayViking Global Investors LP and 8 others10% OwnerSSale−1.40M$29.80−$41.7M−43.1%1.85M after16 lots
Jan 10, 2023 (view filing)Jan 64 daysKlee Justin B.Co-Chief Executive OfficerSSale+5.97K$36.30+$216.6K+0.2%2.89M after2 lots
Jan 10, 2023 (view filing)Jan 64 daysOlinger MargaretChief Commercial OfficerSSale+2.40K$36.30+$87.2K+1.1%214.4K after2 lots
Jan 10, 2023 (view filing)Jan 64 daysFrates James MChief Financial OfficerSSale+2.66K$36.30+$96.5K+8.5%34.0K after2 lots
Jan 10, 2023 (view filing)Jan 64 daysCohen Joshua BCo-Chief Executive OfficerSSale+5.97K$36.30+$216.6K+0.2%2.89M after2 lots
Jan 10, 2023 (view filing)Jan 64 daysYeramian Patrick DChief Medical OfficerSSale+2.03K$36.30+$73.8K+1.0%204.3K after2 lots
Feb 24, 2023 (view filing)Feb 22-232 daysMorningside Venture Investments Ltd10% OwnerSSale−100.0K$35.78−$3.58M−1.3%7.58M after4 lots
Feb 28, 2023 (view filing)Feb 226 daysLateMorningside Venture Investments Ltd10% OwnerSSale−50.0K$34.73−$1.74M−0.7%7.53M after2 lots
Feb 28, 2023 (view filing)Feb 244 daysMazzariello GinaChief Legal OfficerSSale−3.59K$34.49−$123.7K−8.7%37.4K after
Mar 6, 2023 (view filing)Mar 24 daysMorningside Venture Investments Ltd10% OwnerSSale−50.0K$33.75−$1.69M−0.7%7.48M after
Mar 16, 2023 (view filing)Mar 14-152 daysMorningside Venture Investments Ltd10% OwnerSSale−220.7K$33.68−$7.43M−3.0%7.26M after3 lots
Mar 17, 2023 (view filing)Mar 161 dayMorningside Venture Investments Ltd10% OwnerSSale−9.12K$32.55−$296.9K−0.1%7.25M after
Mar 20, 2023 (view filing)Mar 164 daysCohen Joshua BCo-Chief Executive OfficerSSale−100.0K$31.86−$3.19M−3.5%2.79M after2 lots
Mar 20, 2023 (view filing)Mar 164 daysFirestone KarenDirectorPPurchase+1.00K$31.99+$32.0KNew position1.00K after
Mar 20, 2023 (view filing)Mar 164 daysMilne George M JrDirectorSSale−35.0K$31.89−$1.12M−3.9%862.0K after2 lots
Mar 20, 2023 (view filing)Mar 164 daysKlee Justin B.Co-Chief Executive OfficerSSale−100.0K$31.86−$3.19M−3.5%2.79M after2 lots
Mar 23, 2023 (view filing)Mar 212 daysMorningside Venture Investments Ltd10% OwnerSSale−63.4K$31.91−$2.02M−0.9%7.19M after2 lots
Mar 24, 2023 (view filing)Mar 168 daysFrates James MChief Financial OfficerSSale−32.5K$31.89−$1.04M−48.9%34.0K afterAmended2 lots
Mar 24, 2023 (view filing)6:45 PM ETMar 168 daysYeramian Patrick DChief Medical OfficerSSale−54.6K$31.87−$1.74M−21.5%199.3K afterAmended2 lots
Mar 29, 2023 (view filing)Mar 27-282 daysMorningside Venture Investments Ltd10% OwnerSSale−161.0K$30.42−$4.90M−2.2%7.03M after3 lots
Mar 31, 2023 (view filing)Mar 292 daysMorningside Venture Investments Ltd10% OwnerSSale−29.0K$30.45−$884.5K−0.4%7.00M after
Apr 19, 2023 (view filing)7:45 PM ETApr 172 daysYeramian Patrick DChief Medical OfficerSSale−49.6K$30.54−$1.51M−19.2%208.4K after2 lots10b5-1
May 17, 2023 (view filing)4:58 PM ETMay 152 daysYeramian Patrick DChief Medical OfficerSSale−12.0K$29.03−$347.4K−5.4%208.4K after10b5-1
May 18, 2023 (view filing)May 162 daysFrates James MChief Financial OfficerSSale−32.5K$26.94−$875.6K−36.9%55.7K after2 lots10b5-1
Aug 17, 2023 (view filing)Aug 152 daysMazzariello GinaChief Legal OfficerSSale−6.16K$20.88−$128.7K−11.2%49.1K after10b5-1
Dec 19, 2023 (view filing)Dec 154 daysFirestone KarenDirectorPPurchase+4.00K$14.97+$59.9K+400.0%5.00K after
Jan 11, 2024 (view filing)Jan 92 daysYeramian Patrick DChief Medical OfficerSSale−2.81K$16.33−$45.9K−1.3%205.6K after
Jan 11, 2024 (view filing)Jan 92 daysCohen Joshua BCo-Chief Executive OfficerSSale−5.84K$16.33−$95.4K−0.2%2.90M after
Jan 11, 2024 (view filing)Jan 92 daysFrates James MChief Financial OfficerSSale−2.72K$16.33−$44.4K−2.4%112.0K after
Jan 11, 2024 (view filing)Jan 92 daysKlee Justin B.Co-Chief Executive OfficerSSale−5.84K$16.33−$95.4K−0.2%2.84M after
Feb 27, 2024 (view filing)Feb 234 daysMazzariello GinaChief Legal OfficerSSale−2.84K$18.76−$53.2K−5.8%46.2K after
Mar 7, 2024 (view filing)Mar 52 daysFrates James MChief Financial OfficerSSale−1.79K$18.73−$33.6K−1.3%134.8K after
Mar 7, 2024 (view filing)Mar 52 daysMazzariello GinaChief Legal OfficerSSale−1.54K$18.73−$28.8K−1.9%81.4K after
Mar 7, 2024 (view filing)Mar 52 daysKlee Justin B.Co-Chief Executive OfficerSSale−4.13K$18.73−$77.4K−0.1%2.96M after
Mar 7, 2024 (view filing)Mar 52 daysCohen Joshua BCo-Chief Executive OfficerSSale−4.13K$18.73−$77.4K−0.1%3.02M after
May 16, 2024 (view filing)May 151 dayMazzariello GinaChief Legal OfficerSSale−10.5K$1.88−$19.7K−6.5%151.5K after10b5-1
May 16, 2024 (view filing)May 14-152 daysQuimi DaphneDirectorPPurchase+5.00K$1.89+$9.45KNew position5.00K after2 lots
Sep 5, 2024 (view filing)Sep 32 daysMilne George M JrDirectorPPurchase+100.0K$2.20+$220.0K+13.2%858.6K after
Sep 9, 2024 (view filing)Sep 54 daysFirestone KarenDirectorPPurchase+50.0K$2.13+$106.5K+1,000.0%55.0K after
Sep 16, 2024 (view filing)Sep 124 daysFrates James MChief Financial OfficerPPurchase+40.0K$2.53+$101.2K+20.7%233.5K after
Oct 2, 2024 (view filing)Sep 302 daysMazzariello GinaChief Legal OfficerSSale−8.71K$3.20−$27.9K−5.7%142.8K after
Oct 2, 2024 (view filing)Sep 302 daysBedrosian Camille LChief Medical OfficerSSale−11.4K$3.20−$36.6K−7.4%143.8K after