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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 9 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Four kinds of short-selling data, each measuring something different:

  • Short interest: shares sold short and not yet bought back, as of a settlement date. FINRA publishes it twice a month, about eight business days after the settlement date.
  • Daily short volume: shares sold short each day in off-exchange trades reported to FINRA. It counts trades, not open positions, and is published the next day.
  • Fails-to-deliver: shares not delivered by the settlement date. The SEC publishes them twice a month, about two weeks late.
  • ATS (dark pool) volume: weekly volume on alternative trading systems and other off-exchange venues. FINRA publishes it two to four weeks after the week.

More in the glossary.

Short interest

Shares sold short and not yet bought back, from FINRA, on every settlement date in the last two years.

Short interest
12.8M
Shares, settlement Oct 30, 2026
Change
−426.1K
−3.2% vs. Oct 15, 2026
Days to cover
10.47
Short interest ÷ average daily volume
Average daily volume
1.22M
Shares, as reported by FINRA
Short interest by settlement date
Oct 31, 2024: 1,289,340 sharesNov 15, 2024: 1,526,219 sharesNov 29, 2024: 1,448,789 sharesDec 13, 2024: 1,565,509 sharesDec 31, 2024: 1,942,447 sharesJan 15, 2025: 2,482,384 sharesJan 31, 2025: 2,591,408 sharesFeb 14, 2025: 3,378,306 sharesFeb 28, 2025: 3,652,423 sharesMar 14, 2025: 3,747,333 sharesMar 31, 2025: 3,775,634 sharesApr 15, 2025: 4,312,023 sharesApr 30, 2025: 4,198,819 sharesMay 15, 2025: 4,972,837 sharesMay 30, 2025: 4,131,846 sharesJun 13, 2025: 4,039,910 sharesJun 30, 2025: 6,622,803 sharesJul 15, 2025: 7,466,420 sharesJul 31, 2025: 7,192,631 sharesAug 15, 2025: 7,433,417 sharesAug 29, 2025: 8,410,918 sharesSep 15, 2025: 8,774,952 sharesSep 30, 2025: 10,066,534 sharesOct 15, 2025: 9,616,175 sharesOct 31, 2025: 10,449,446 sharesNov 14, 2025: 11,911,669 sharesNov 28, 2025: 11,623,612 sharesDec 15, 2025: 12,068,995 sharesDec 31, 2025: 13,642,380 sharesJan 15, 2026: 13,437,426 sharesJan 30, 2026: 13,752,736 sharesFeb 13, 2026: 14,310,589 sharesFeb 27, 2026: 14,497,298 sharesMar 13, 2026: 13,864,210 sharesMar 31, 2026: 14,231,261 sharesApr 15, 2026: 14,831,510 sharesApr 30, 2026: 14,800,969 sharesMay 15, 2026: 14,514,401 sharesMay 29, 2026: 14,957,523 sharesJun 15, 2026: 13,121,697 sharesJun 30, 2026: 14,385,180 sharesJul 15, 2026: 12,265,993 sharesJul 31, 2026: 13,401,722 sharesAug 14, 2026: 13,425,106 sharesAug 31, 2026: 12,737,201 sharesSep 15, 2026: 13,512,753 sharesSep 30, 2026: 12,666,971 sharesOct 15, 2026: 13,249,442 sharesOct 30, 2026: 12,823,384 shares
Short interest in AMLX by settlement date
Settlement dateShort interestChangeChange %Avg. daily volumeDays to cover
Oct 30, 202612.8M−426.1K−3.2%1.22M10.47
Oct 15, 202613.2M+582.5K+4.6%1.33M9.93
Sep 30, 202612.7M−845.8K−6.3%1.38M9.16
Sep 15, 202613.5M+775.6K+6.1%1.56M8.64
Aug 31, 202612.7M−687.9K−5.1%5.38M2.37
Aug 14, 202613.4M+23.4K+0.2%1.88M7.14
Jul 31, 202613.4M+1.14M+9.3%1.96M6.84
Jul 15, 202612.3M−2.12M−14.7%1.33M9.21
Jun 30, 202614.4M+1.26M+9.6%2.04M7.06
Jun 15, 202613.1M−1.84M−12.3%1.62M8.12
May 29, 202615.0M+443.1K+3.1%916.1K16.33
May 15, 202614.5M−286.6K−1.9%1.19M12.16
Apr 30, 202614.8M−30.5K−0.2%1.04M14.26
Apr 15, 202614.8M+600.2K+4.2%1.21M12.23
Mar 31, 202614.2M+367.1K+2.7%1.01M14.14
Mar 13, 202613.9M−633.1K−4.4%1.11M12.49
Feb 27, 202614.5M+186.7K+1.3%760.3K19.07
Feb 13, 202614.3M+557.9K+4.1%821.0K17.43
Jan 30, 202613.8M+315.3K+2.4%2.09M6.59
Jan 15, 202613.4M−205.0K−1.5%1.74M7.70
Dec 31, 202513.6M+1.57M+13.0%1.82M7.51
Dec 15, 202512.1M+445.4K+3.8%1.11M10.90
Nov 28, 202511.6M−288.1K−2.4%1.40M8.31
Nov 14, 202511.9M+1.46M+14.0%1.59M7.48
Oct 31, 202510.4M+833.3K+8.7%1.53M6.85
Oct 15, 20259.62M−450.4K−4.5%1.92M5.01
Sep 30, 202510.1M+1.29M+14.7%1.98M5.09
Sep 15, 20258.77M+364.0K+4.3%2.26M3.88
Aug 29, 20258.41M+977.5K+13.2%1.55M5.44
Aug 15, 20257.43M+240.8K+3.4%890.1K8.35
Jul 31, 20257.19M−273.8K−3.7%1.22M5.92
Jul 15, 20257.47M+843.6K+12.7%1.93M3.86
Jun 30, 20256.62M+2.58M+63.9%2.60M2.54
Jun 13, 20254.04M−91.9K−2.2%849.5K4.76
May 30, 20254.13M−841.0K−16.9%1.03M4.01
May 15, 20254.97M+774.0K+18.4%1.12M4.43
Apr 30, 20254.20M−113.2K−2.6%825.4K5.09
Apr 15, 20254.31M+536.4K+14.2%862.2K5.00
Mar 31, 20253.78M+28.3K+0.8%627.5K6.02
Mar 14, 20253.75M+94.9K+2.6%1.04M3.59
Feb 28, 20253.65M+274.1K+8.1%554.5K6.59
Feb 14, 20253.38M+786.9K+30.4%755.6K4.47
Jan 31, 20252.59M+109.0K+4.4%1.05M2.47
Jan 15, 20252.48M+539.9K+27.8%808.4K3.07
Dec 31, 20241.94M+376.9K+24.1%731.1K2.66
Dec 13, 20241.57M+116.7K+8.1%722.2K2.17
Nov 29, 20241.45M−77.4K−5.1%1.24M1.17
Nov 15, 20241.53M+236.9K+18.4%1.62M1.00
Oct 31, 20241.29M+279.1K+27.6%2.07M1.00

Fails-to-deliver

Shares that weren't delivered by the settlement date, from the SEC, for the last 30 dates with fails. The price is the previous day's closing price published by the SEC.

Fails-to-deliver in AMLX by settlement date
Settlement dateSharesPriceValue
Sep 21, 202666$32.41$2.14K
Aug 31, 20261$34.74$34.74
Aug 26, 202642$37.46$1.57K
Aug 25, 2026154$38.15$5.88K
Aug 24, 20261,488$38.66$57.5K
Aug 21, 20266,973$39.66$276.5K
Aug 19, 202663,699$35.11$2.24M
Aug 10, 2026297$22.82$6.78K
Jul 28, 202621$19.49$409.29
Jul 24, 2026100$17.59$1.76K
Jul 23, 2026100$17.70$1.77K
Jul 22, 2026100$18.50$1.85K
Jul 14, 2026140$17.41$2.44K
Jul 8, 2026859$18.17$15.6K
Jun 22, 202613,556$15.67$212.4K
Jun 15, 2026186$14.59$2.71K
Jun 4, 20263$13.20$39.6
Jun 2, 202640$14.07$562.8
Jun 1, 202613,737$14.35$197.1K
May 22, 202613$13.93$181.09
May 19, 202636$12.86$462.96
May 18, 20268,340$13.29$110.8K
May 13, 202616,807$14.44$242.7K
Apr 30, 2026347$15.60$5.41K
Apr 14, 2026173$16.47$2.85K
Apr 6, 20268$14.95$119.6
Mar 24, 202689,736$13.53$1.21M
Mar 17, 202623$14.38$330.74
Mar 13, 2026683$14.38$9.82K
Mar 5, 20264,372$15.05$65.8K

Daily short volume

Off-exchange short-sale volume, not short interest: shares sold short each day in trades reported to FINRA, for the last 30 trading days.

The short volume ratio isn't a sentiment gauge: market makers sell short to fill buy orders and to hedge, so short sales are usually about half of off-exchange volume.

Off-exchange short volume in AMLX by trade date
Trade dateShort volumeShort exemptOff-exchange volumeShort volume ratio
Nov 12, 2026485,350600664,90873.0%
Nov 11, 2026506,9370905,52856.0%
Nov 10, 2026433,1950787,16455.0%
Nov 9, 2026242,3610474,77851.0%
Nov 6, 2026340,574527835,73040.8%
Nov 5, 2026417,5740953,78743.8%
Nov 4, 2026286,883100792,71336.2%
Nov 3, 2026237,136378449,39452.8%
Nov 2, 2026255,6332,300421,70260.6%
Oct 30, 2026253,927581345,28573.5%
Oct 29, 2026213,5920370,00257.7%
Oct 28, 2026219,3689,234574,97238.2%
Oct 27, 2026298,49214,224467,29063.9%
Oct 26, 2026463,22117768,13060.3%
Oct 23, 2026149,7360556,62926.9%
Oct 22, 2026255,7640547,13146.7%
Oct 21, 2026492,3910674,15573.0%
Oct 20, 2026319,6610884,66736.1%
Oct 19, 2026195,8840561,79534.9%
Oct 16, 2026201,7855554,55436.4%
Oct 15, 2026188,8680299,98263.0%
Oct 14, 2026285,9230392,31872.9%
Oct 13, 2026360,2760493,93972.9%
Oct 12, 2026281,3410438,94264.1%
Oct 9, 2026317,8400557,89957.0%
Oct 8, 2026352,89801,065,50833.1%
Oct 7, 2026388,1200612,58863.4%
Oct 6, 2026335,0390609,04055.0%
Oct 5, 2026168,869295380,27544.4%
Oct 2, 2026283,08817385,89973.4%

ATS (dark pool) volume

Weekly volume on alternative trading systems (ATS) and other off-exchange (OTC) venues, from FINRA, for the last 12 weeks. ATS share is ATS volume ÷ (ATS + OTC volume), not a share of all trading.

Weekly ATS and OTC volume in AMLX
Week ofTierATS sharesATS tradesOther OTC sharesOther OTC tradesATS share
Oct 5, 2026T22,383,25437,7101,780,3195,43257.2%
Sep 28, 2026T21,539,75641,205968,0696,72861.4%
Sep 21, 2026T22,244,59840,657917,2966,79071.0%
Sep 14, 2026T22,371,55042,1501,649,4448,12359.0%
Sep 7, 2026T21,789,49831,999795,3935,70869.2%
Aug 31, 2026T22,605,24444,0991,471,7178,31863.9%
Aug 24, 2026T23,171,29352,4602,702,76611,06854.0%
Aug 17, 2026T211,166,827118,97711,588,71775,15649.1%
Aug 10, 2026T21,999,37248,959648,6986,70775.5%
Aug 3, 2026T23,934,26260,1771,826,2148,47568.3%
Jul 27, 2026T24,063,30752,8752,976,5526,76657.7%
Jul 20, 2026T22,034,12541,0241,810,4566,72852.9%