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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
143
−35 vs. Q4 2023
Shares held
49.5M
−10.8M (−17.9%) vs. Q4 2023
Total value
$141.5M
−$745.9M (−84.1%) vs. Q4 2023
New holders
25
56 more added
Sold out
60
48 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 143 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ1 2024: $141.5M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding AMLX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd74$00.00%−3,652−98.0%Reduced
Nisa Investment Advisors, LLC10$280.00%−24−70.6%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC10$280.00%+10New
Kelly Financial Services LLC33$940.00%00.0%Unchanged
GAMMA Investing LLC35$990.00%00.0%Unchanged
Salem Investment Counselors Inc55$1570.00%00.0%Unchanged
Russell Investments Group, Ltd.162$4600.00%−2,675−94.3%Reduced
Fernwood Investment Management, LLC200$5680.00%+200New
The PNC Financial Services Group, Inc.214$6080.00%+18+9.2%Added
Daiwa Securities Group Inc.266$1.00K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.389$1.10K0.00%−2,761−87.7%Reduced
Cutler Group LP1,000$2.00K0.00%+100+11.1%Added
Royal Bank of Canada1,352$3.00K0.00%−14,803−91.6%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$3.57K0.00%00.0%Unchanged
Amalgamated Bank1,726$5.00K0.00%−5,478−76.0%Reduced
Steward Partners Investment Advisory, LLC2,000$5.68K0.00%00.0%Unchanged
Metropolitan Life Insurance Co2,899$8.23K0.00%00.0%Unchanged
Quarry LP3,000$8.52K0.00%+2,250+300.0%Added
Ameritas Investment Partners, Inc.5,046$14.3K0.00%00.0%Unchanged
Banque Cantonale Vaudoise5,900$17.0K0.00%+5,900New
Advisors Asset Management, Inc.8,350$23.7K0.00%−273−3.2%Reduced
Primecap Management Co10,000$28.4K0.00%−146,900−93.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)10,022$28.5K0.00%−367−3.5%Reduced
Tower Research Capital LLC (TRC)10,296$29.2K0.00%−2,018−16.4%Reduced
Cipher Capital LP10,717$30.4K0.01%+10,717New
Wolverine Trading, LLC11,571$32.9K0.00%+11,571New
Arizona State Retirement System12,061$34.3K0.00%+759+6.7%Added
Tudor Investment Corp Et Al12,753$36.2K0.00%−20,899−62.1%Reduced
China Universal Asset Management Co., Ltd.13,004$36.9K0.00%+5,189+66.4%Added
Teza Capital Management LLC13,431$38.1K0.01%−1,229−8.4%Reduced
Victory Capital Management Inc13,514$38.4K0.00%+13,514New
MetLife Investment Management13,768$39.1K0.00%−12,944−48.5%Reduced
ProShare Advisors LLC13,874$39.4K0.00%+1,153+9.1%Added
CWM, LLC14,030$40.0K0.00%+827+6.3%Added
Principal Financial Group Inc14,666$41.7K0.00%+194+1.3%Added
Janus Henderson Group PLC14,717$41.9K0.00%−36−0.2%Reduced
Handelsbanken Fonder AB14,700$42.0K0.00%+2,800+23.5%Added
Allspring Global Investments Holdings, LLC15,276$43.4K0.00%+15,247+52,575.9%Added
STRS Ohio16,500$46.0K0.00%−1,000−5.7%Reduced
Guggenheim Capital LLC16,338$46.4K0.00%+1,392+9.3%Added
Voya Investment Management LLC17,357$49.3K0.00%−2,818−14.0%Reduced
Two Sigma Securities, LLC18,141$51.5K0.00%+18,141New
FMR LLC19,390$55.1K0.00%−1,416,761−98.6%Reduced
UBS Asset Management Americas Inc19,700$55.9K0.00%00.0%Unchanged
Brown Advisory Inc19,961$56.7K0.00%+6,500+48.3%Added
Premier Path Wealth Partners, LLC20,265$57.6K0.01%00.0%Unchanged
Wells Fargo & Company20,949$59.5K0.00%−13,316−38.9%Reduced
New York State Common Retirement Fund21,244$60.3K0.00%−2,510−10.6%Reduced
Parallel Advisors, LLC21,376$60.7K0.00%+21,376New
Parsons Capital Management Inc21,945$62.3K0.00%00.0%Unchanged
Invesco Ltd.24,349$69.2K0.00%+454+1.9%Added
Maven Securities LTD25,000$71.0K0.00%+25,000New
American International Group, Inc.25,031$71.1K0.00%−215−0.9%Reduced
Virtus ETF Advisers LLC25,849$73.4K0.04%+3,719+16.8%Added
SG Americas Securities, LLC26,139$74.0K0.00%−39,900−60.4%Reduced
GTS Securities LLC29,403$83.5K0.00%+3,092+11.8%Added
Legal & General Group Plc32,854$93.3K0.00%−6,812−17.2%Reduced
Twinbeech Capital LP33,604$95.4K0.00%−132,840−79.8%Reduced
Wellington Management Group LLP33,933$96.4K0.00%−10,820−24.2%Reduced
Credit Suisse AG36,643$104.1K0.00%−1,409−3.7%Reduced
ADAR1 Capital Management, LLC38,858$110.4K0.03%−38,700−49.9%Reduced
California State Teachers Retirement System44,561$126.6K0.00%+173+0.4%Added
HSBC Holdings PLC48,307$137.2K0.00%+48,307New
Point72 (DIFC) Ltd48,993$139.1K0.01%+48,993New
Mariner, LLC49,268$139.9K0.00%−163−0.3%Reduced
Legacy Advisors, LLC50,000$142.0K0.02%00.0%Unchanged
Alliancebernstein L.P.51,542$146.4K0.00%00.0%Unchanged
Rafferty Asset Management, LLC53,201$151.1K0.00%+34,881+190.4%Added
Man Group plc60,679$172.3K0.00%+60,679New
Profund Advisors LLC64,969$184.5K0.01%+40,362+164.0%Added
Rhumbline Advisers69,403$197.1K0.00%+1,120+1.6%Added
Mackenzie Financial Corp72,572$206.1K0.00%+72,572New
Healthcare of Ontario Pension Plan Trust Fund73,130$207.7K0.00%00.0%Unchanged
Gsa Capital Partners LLP79,652$226.0K0.02%−52,525−39.7%Reduced
Capstone Investment Advisors, LLC80,084$227.4K0.00%+60,084+300.4%Added
Simplex Trading, LLC82,107$233.0K0.01%−47,315−36.6%Reduced
State Board of Administration of Florida Retirement System8,310$243.8K0.00%−6,270−43.0%Reduced
Swiss National Bank86,600$245.9K0.00%+6,900+8.7%Added
Manufacturers Life Insurance Company, The95,570$271.4K0.00%+9,922+11.6%Added
Tang Capital Management LLC100,000$284.0K0.03%−100,000−50.0%Reduced
Boothbay Fund Management, LLC102,777$291.9K0.01%−116,564−53.1%Reduced
Barclays PLC106,842$303.4K0.00%+15,963+17.6%Added
Hennion & Walsh Asset Management, Inc.112,867$320.5K0.02%+27,937+32.9%Added
AQR Capital Management LLC116,489$330.8K0.00%+93,145+399.0%Added
Standard Life Aberdeen plc118,247$335.8K0.00%−77,246−39.5%Reduced
Winton Group Ltd119,676$339.9K0.02%+119,676New
TD Asset Management Inc131,200$372.6K0.00%+16,200+14.1%Added
Nuveen Asset Management, LLC137,973$391.8K0.00%−883,684−86.5%Reduced
Alps Advisors Inc139,250$395.5K0.00%+89,522+180.0%Added
Aviva PLC145,418$413.0K0.00%+145,418New
Squarepoint Ops LLC159,309$452.4K0.00%+125,859+376.3%Added
PDT Partners, LLC166,896$474.0K0.04%+107,929+183.0%Added
Point72 Asset Management, L.P.170,000$482.8K0.00%−2,581,305−93.8%Reduced
First Trust Advisors LP170,478$484.2K0.00%+153,098+880.9%Added
Federated Hermes, Inc.175,983$499.8K0.00%+73,483+71.7%Added
Cubist Systematic Strategies, LLC176,114$500.2K0.01%−260,721−59.7%Reduced
Panagora Asset Management Inc189,016$536.8K0.00%+189,016New
Atom Investors LP189,796$539.0K0.07%+189,796New
Bank of New York Mellon Corp198,029$562.4K0.00%+7,029+3.7%Added
UBS Group AG210,573$598.0K0.00%+171,559+439.7%Added