Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 178
- +9 vs. Q3 2023
- Shares held
- 60.3M
- +1.65M (+2.8%) vs. Q3 2023
- Total value
- $887.4M
- −$186.2M (−17.3%) vs. Q3 2023
- New holders
- 37
- 78 more added
- Sold out
- 28
- 46 more reduced
1 institution that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 5,275,566 | $77.7M | 0.00% | +225,486+4.5% | Added |
| BlackRock Inc. | 4,002,334 | $58.9M | 0.00% | +426,875+11.9% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $43.6M | 0.16% | 00.0% | Unchanged |
| Morgan Stanley | 2,830,243 | $41.7M | 0.00% | +1,878,124+197.3% | Added |
| Point72 Asset Management, L.P. | 2,751,305 | $40.5M | 0.12% | +2,751,259+5,980,997.8% | Added |
| Stonepine Capital Management, LLC | 2,500,000 | $36.8M | 15.92% | −15,868−0.6% | Reduced |
| Millennium Management LLC | 2,272,643 | $33.5M | 0.03% | +153,108+7.2% | Added |
| Citadel Advisors LLC | 2,240,885 | $33.0M | 0.03% | +1,013,941+82.6% | Added |
| Perceptive Advisors LLC | 1,869,125 | $27.5M | 0.62% | −819,748−30.5% | Reduced |
| State Street Corp | 1,441,402 | $21.2M | 0.00% | +201,649+16.3% | Added |
| FMR LLC | 1,436,151 | $21.1M | 0.00% | +997,465+227.4% | Added |
| Franklin Resources Inc | 1,325,001 | $19.5M | 0.01% | +707,134+114.4% | Added |
| Goldman Sachs Group Inc | 1,256,861 | $18.5M | 0.00% | +69,733+5.9% | Added |
| Jane Street Group, LLC | 1,157,165 | $17.0M | 0.02% | +555,877+92.4% | Added |
| Eventide Asset Management, LLC | 1,116,837 | $16.4M | 0.27% | 00.0% | Unchanged |
| Saturn V Capital Management LLC | 1,099,268 | $16.2M | 6.19% | +213,125+24.1% | Added |
| Jupiter Asset Management Ltd | 1,060,900 | $15.6M | 0.15% | +411,164+63.3% | Added |
| Geode Capital Management, LLC | 1,030,716 | $15.2M | 0.00% | +48,648+5.0% | Added |
| Nuveen Asset Management, LLC | 1,021,657 | $15.0M | 0.00% | +21,306+2.1% | Added |
| Marshall Wace, LLP | 985,114 | $14.5M | 0.03% | −212,646−17.8% | Reduced |
| Price T Rowe Associates Inc | 894,780 | $13.2M | 0.00% | +870,560+3,594.4% | Added |
| Ikarian Capital, LLC | 877,500 | $12.9M | 3.53% | +877,500 | New |
| Deutsche Bank AG | 853,000 | $12.6M | 0.01% | +828,584+3,393.6% | Added |
| Falcon Edge Capital, LP | 846,240 | $12.5M | 6.01% | −7,022−0.8% | Reduced |
| Emerald Advisers, LLC | 802,610 | $11.8M | 0.51% | −35,962−4.3% | Reduced |
| GMT Capital Corp | 786,000 | $11.6M | 0.44% | +209,700+36.4% | Added |
| Emerald Mutual Fund Advisers Trust | 656,530 | $9.66M | 0.51% | −24,780−3.6% | Reduced |
| Nantahala Capital Management, LLC | 620,110 | $9.13M | 0.91% | +212,905+52.3% | Added |
| Walleye Capital LLC | 582,728 | $8.58M | 0.12% | +481,769+477.2% | Added |
| Susquehanna International Group, LLP | 562,940 | $8.29M | 0.01% | +346,186+159.7% | Added |
| D. E. Shaw & Co., Inc. | 546,965 | $8.05M | 0.01% | −213,325−28.1% | Reduced |
| American Century Companies Inc | 542,546 | $7.99M | 0.01% | +542,546 | New |
| Rock Springs Capital Management LP | 535,012 | $7.88M | 0.19% | −1,010,004−65.4% | Reduced |
| Group One Trading, L.P. | 503,672 | $7.41M | 0.23% | +466,301+1,247.8% | Added |
| Qube Research & Technologies Ltd | 482,599 | $7.10M | 0.02% | +319,889+196.6% | Added |
| Woodline Partners LP | 470,801 | $6.93M | 0.08% | −428,499−47.6% | Reduced |
| Voloridge Investment Management, LLC | 465,445 | $6.85M | 0.03% | +196,478+73.0% | Added |
| Hudson Bay Capital Management LP | 460,600 | $6.78M | 0.06% | −221,623−32.5% | Reduced |
| Cubist Systematic Strategies, LLC | 436,835 | $6.43M | 0.08% | +236,645+118.2% | Added |
| Northern Trust Corp | 435,437 | $6.41M | 0.00% | +9,659+2.3% | Added |
| Citigroup Inc | 387,664 | $5.71M | 0.01% | +343,875+785.3% | Added |
| Charles Schwab Investment Management Inc | 387,620 | $5.71M | 0.00% | +21,758+5.9% | Added |
| Dark Forest Capital Management LP | 312,463 | $4.60M | 0.69% | +212,307+212.0% | Added |
| Schroder Investment Management Group | 295,000 | $4.34M | 0.01% | +295,000 | New |
| Ally Bridge Group (NY) LLC | 275,773 | $4.06M | 2.92% | +3,083+1.1% | Added |
| Trexquant Investment LP | 265,046 | $3.90M | 0.09% | +265,046 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 256,606 | $3.78M | 0.02% | +132,151+106.2% | Added |
| Polar Asset Management Partners Inc. | 242,300 | $3.57M | 0.10% | +210,300+657.2% | Added |
| Boothbay Fund Management, LLC | 219,341 | $3.23M | 0.12% | +219,341 | New |
| Tang Capital Management LLC | 200,000 | $2.94M | 0.27% | +200,000 | New |
| Standard Life Aberdeen plc | 195,493 | $2.88M | 0.01% | +195,493 | New |
| Bank of New York Mellon Corp | 191,000 | $2.81M | 0.00% | +27,405+16.8% | Added |
| Sphera Funds Management Ltd. | 183,650 | $2.70M | 0.50% | −10,000−5.2% | Reduced |
| Twinbeech Capital LP | 166,444 | $2.45M | 0.04% | +84,860+104.0% | Added |
| Primecap Management Co | 156,900 | $2.31M | 0.00% | −148,000−48.5% | Reduced |
| AlphaCentric Advisors LLC | 151,000 | $2.22M | 1.49% | +5,500+3.8% | Added |
| Algert Global LLC | 147,020 | $2.16M | 0.09% | −14,385−8.9% | Reduced |
| Gsa Capital Partners LLP | 132,177 | $1.95M | 0.16% | +89,742+211.5% | Added |
| Simplex Trading, LLC | 129,422 | $1.91M | 0.06% | +106,870+473.9% | Added |
| DAFNA Capital Management LLC | 122,547 | $1.80M | 0.43% | 00.0% | Unchanged |
| Bank of America Corp | 120,328 | $1.77M | 0.00% | +42,142+53.9% | Added |
| Altium Capital Management LP | 119,526 | $1.76M | 1.21% | −415,174−77.6% | Reduced |
| Norges Bank | 116,400 | $1.71M | 0.00% | +116,400 | New |
| TD Asset Management Inc | 115,000 | $1.69M | 0.00% | +115,000 | New |
| Federated Hermes, Inc. | 102,500 | $1.51M | 0.00% | −221,760−68.4% | Reduced |
| Barclays PLC | 90,879 | $1.34M | 0.00% | +65,180+253.6% | Added |
| Phocas Financial Corp. | 86,073 | $1.27M | 0.17% | +86,073 | New |
| Manufacturers Life Insurance Company, The | 85,648 | $1.26M | 0.00% | +58,518+215.7% | Added |
| Hennion & Walsh Asset Management, Inc. | 84,930 | $1.25M | 0.07% | +35,364+71.3% | Added |
| Sectoral Asset Management Inc | 84,055 | $1.24M | 0.53% | +10,400+14.1% | Added |
| StemPoint Capital LP | 83,381 | $1.23M | 0.33% | +83,381 | New |
| DekaBank Deutsche Girozentrale | 83,000 | $1.22M | 0.00% | +50,000+151.5% | Added |
| Swiss National Bank | 79,700 | $1.17M | 0.00% | +13,200+19.8% | Added |
| ADAR1 Capital Management, LLC | 77,558 | $1.14M | 0.51% | +77,558 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 73,130 | $1.08M | 0.00% | −49,000−40.1% | Reduced |
| ExodusPoint Capital Management, LP | 72,824 | $1.07M | 0.01% | −501,799−87.3% | Reduced |
| JPMorgan Chase & Co | 71,888 | $1.06M | 0.00% | −19,077−21.0% | Reduced |
| Renaissance Technologies LLC | 71,288 | $1.05M | 0.00% | −78,812−52.5% | Reduced |
| Rhumbline Advisers | 68,283 | $1.01M | 0.00% | −677−1.0% | Reduced |
| Seven Eight Capital, LP | 66,801 | $983.3K | 0.11% | +6,910+11.5% | Added |
| SG Americas Securities, LLC | 66,039 | $972.0K | 0.01% | +44,784+210.7% | Added |
| Avidity Partners Management LP | 64,501 | $949.5K | 0.04% | −1,692,439−96.3% | Reduced |
| Janney Montgomery Scott LLC | 59,111 | $870.0K | 0.00% | +16,327+38.2% | Added |
| PDT Partners, LLC | 58,967 | $868.0K | 0.10% | +58,967 | New |
| Nebula Research & Development LLC | 57,850 | $851.6K | 0.26% | +29,828+106.4% | Added |
| Brevan Howard Capital Management LP | 53,517 | $787.8K | 0.08% | +53,517 | New |
| Alliancebernstein L.P. | 51,542 | $758.7K | 0.00% | 00.0% | Unchanged |
| Legacy Advisors, LLC | 50,000 | $736.0K | 0.10% | 00.0% | Unchanged |
| Alps Advisors Inc | 49,728 | $732.0K | 0.01% | +32+0.1% | Added |
| Mariner, LLC | 49,431 | $727.6K | 0.00% | +806+1.7% | Added |
| Y-Intercept (Hong Kong) Ltd | 49,204 | $724.3K | 0.07% | +49,204 | New |
| Caption Management, LLC | 47,000 | $691.8K | 0.08% | −42,256−47.3% | Reduced |
| Wellington Management Group LLP | 44,753 | $658.8K | 0.00% | +44,753 | New |
| Cornercap Investment Counsel Inc | 44,487 | $654.8K | 0.11% | −2,647−5.6% | Reduced |
| California State Teachers Retirement System | 44,388 | $653.4K | 0.00% | +6,469+17.1% | Added |
| Two Sigma Investments, LP | 43,800 | $644.7K | 0.00% | +43,800 | New |
| HRT Financial LP | 42,192 | $621.0K | 0.00% | +16,098+61.7% | Added |
| Legal & General Group Plc | 39,666 | $583.9K | 0.00% | +7,564+23.6% | Added |
| UBS Group AG | 39,014 | $574.3K | 0.00% | +34,403+746.1% | Added |
| Credit Suisse AG | 38,052 | $560.1K | 0.00% | +3,739+10.9% | Added |