Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 147
- +14 vs. Q4 2022
- Shares held
- 51.4M
- +2.80M (+5.8%) vs. Q4 2022
- Total value
- $1.51B
- −$286.0M (−15.9%) vs. Q4 2022
- New holders
- 38
- 60 more added
- Sold out
- 24
- 36 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 6,034,644 | $177.1M | 5.24% | −53,689−0.9% | Reduced |
| Vanguard Group Inc | 4,747,341 | $139.3M | 0.00% | +388,849+8.9% | Added |
| BlackRock Inc. | 3,614,918 | $106.1M | 0.00% | −2,008−0.1% | Reduced |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $86.9M | 0.41% | −1,672,051−36.1% | Reduced |
| Boxer Capital, LLC | 2,084,000 | $61.1M | 3.00% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 2,022,370 | $59.3M | 0.10% | +638,638+46.2% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,984,333 | $58.2M | 1.30% | −708,667−26.3% | Reduced |
| Federated Hermes, Inc. | 1,846,117 | $54.2M | 0.14% | +231,272+14.3% | Added |
| Rock Springs Capital Management LP | 1,452,816 | $42.6M | 1.02% | +223,179+18.1% | Added |
| Pictet Asset Management SA | 1,433,846 | $42.1M | 0.05% | +312,081+27.8% | Added |
| Goldman Sachs Group Inc | 1,366,172 | $40.1M | 0.01% | +329,902+31.8% | Added |
| Marshall Wace, LLP | 1,139,240 | $33.4M | 0.08% | +1,139,240 | New |
| Millennium Management LLC | 1,074,610 | $31.5M | 0.04% | +215,195+25.0% | Added |
| State Street Corp | 1,066,238 | $31.3M | 0.00% | −9,374−0.9% | Reduced |
| Adage Capital Partners GP, L.L.C. | 1,007,336 | $29.6M | 0.07% | −901,865−47.2% | Reduced |
| Emerald Advisers, LLC | 972,835 | $28.5M | 1.37% | +135,926+16.2% | Added |
| Falcon Edge Capital, LP | 930,337 | $27.3M | 10.08% | +109,117+13.3% | Added |
| Morgan Stanley | 902,547 | $26.5M | 0.00% | +418,078+86.3% | Added |
| Avidity Partners Management LP | 900,000 | $26.4M | 0.88% | +900,000 | New |
| Geode Capital Management, LLC | 890,982 | $26.1M | 0.00% | +37,069+4.3% | Added |
| OrbiMed Advisors LLC | 813,500 | $23.9M | 0.47% | +813,500 | New |
| Emerald Mutual Fund Advisers Trust | 789,591 | $23.2M | 1.37% | +134,576+20.5% | Added |
| Great Point Partners LLC | 783,795 | $23.0M | 4.55% | +593,795+312.5% | Added |
| Voya Investment Management LLC | 619,030 | $18.2M | 0.02% | +576,884+1,368.8% | Added |
| Nuveen Asset Management, LLC | 611,932 | $18.0M | 0.01% | +15,878+2.7% | Added |
| Ghost Tree Capital, LLC | 475,000 | $13.9M | 5.27% | +125,000+35.7% | Added |
| Avoro Capital Advisors LLC | 473,100 | $13.9M | 0.21% | −156,900−24.9% | Reduced |
| Northern Trust Corp | 463,880 | $13.6M | 0.00% | +68,741+17.4% | Added |
| Eventide Asset Management, LLC | 458,054 | $13.4M | 0.25% | +208,054+83.2% | Added |
| Woodline Partners LP | 434,200 | $12.7M | 0.18% | −74,153−14.6% | Reduced |
| Balyasny Asset Management LLC | 420,841 | $12.3M | 0.04% | −224,712−34.8% | Reduced |
| ExodusPoint Capital Management, LP | 393,904 | $11.6M | 0.13% | +189,967+93.1% | Added |
| Point72 Asset Management, L.P. | 324,800 | $9.53M | 0.03% | −1,803,160−84.7% | Reduced |
| Charles Schwab Investment Management Inc | 320,086 | $9.39M | 0.00% | +2,367+0.7% | Added |
| Schonfeld Strategic Advisors LLC | 285,005 | $8.36M | 0.08% | +173,081+154.6% | Added |
| Allspring Global Investments Holdings, LLC | 277,788 | $8.15M | 0.01% | +11,769+4.4% | Added |
| Jane Street Group, LLC | 264,858 | $7.77M | 0.01% | +128,301+94.0% | Added |
| Alyeska Investment Group, L.P. | 251,407 | $7.38M | 0.07% | +201,407+402.8% | Added |
| Lord, Abbett & Co. LLC | 250,042 | $7.34M | 0.03% | +250,042 | New |
| Sectoral Asset Management Inc | 242,400 | $7.11M | 1.37% | +84,450+53.5% | Added |
| Citadel Advisors LLC | 228,906 | $6.72M | 0.01% | +172,149+303.3% | Added |
| Verition Fund Management LLC | 221,598 | $6.50M | 0.10% | −38,953−15.0% | Reduced |
| Ameriprise Financial Inc | 212,453 | $6.23M | 0.00% | +8,377+4.1% | Added |
| Bank of New York Mellon Corp | 204,656 | $6.00M | 0.00% | −5,483−2.6% | Reduced |
| Altium Capital Management LP | 185,000 | $5.43M | 3.24% | +45,000+32.1% | Added |
| Polar Asset Management Partners Inc. | 177,200 | $5.20M | 0.09% | +177,200 | New |
| Voloridge Investment Management, LLC | 135,465 | $3.97M | 0.02% | −159,802−54.1% | Reduced |
| Twinbeech Capital LP | 131,772 | $3.87M | 0.08% | +131,772 | New |
| Wellington Management Group LLP | 108,429 | $3.18M | 0.00% | +40,524+59.7% | Added |
| JPMorgan Chase & Co | 101,700 | $2.98M | 0.00% | +51,999+104.6% | Added |
| Maven Securities LTD | 100,000 | $2.93M | 0.46% | −50,000−33.3% | Reduced |
| Tang Capital Management LLC | 100,000 | $2.93M | 0.44% | 00.0% | Unchanged |
| HRT Financial LP | 93,790 | $2.75M | 0.03% | +93,790 | New |
| Norges Bank | 91,900 | $2.70M | 0.00% | +10,700+13.2% | Added |
| Squarepoint Ops LLC | 91,726 | $2.69M | 0.02% | +51,726+129.3% | Added |
| Barclays PLC | 81,906 | $2.40M | 0.00% | +43,411+112.8% | Added |
| Rhumbline Advisers | 75,962 | $2.23M | 0.00% | +4,398+6.1% | Added |
| SEI Investments Co | 69,665 | $2.04M | 0.00% | +55,888+405.7% | Added |
| Bank of America Corp | 68,324 | $2.00M | 0.00% | +4,958+7.8% | Added |
| J. Goldman & Co LP | 68,278 | $2.00M | 0.12% | +22,636+49.6% | Added |
| Cubist Systematic Strategies, LLC | 63,998 | $1.88M | 0.02% | +60,192+1,581.5% | Added |
| Soleus Capital Management, L.P. | 63,214 | $1.85M | 0.23% | +12,578+24.8% | Added |
| Oberweis Asset Management Inc | 60,305 | $1.77M | 0.27% | +60,305 | New |
| Weiss Multi-Strategy Advisers LLC | 54,054 | $1.59M | 0.04% | +54,054 | New |
| Alliancebernstein L.P. | 51,542 | $1.51M | 0.00% | +15,300+42.2% | Added |
| Mariner, LLC | 48,605 | $1.43M | 0.00% | +10,614+27.9% | Added |
| Putnam Investments LLC | 48,321 | $1.42M | 0.00% | +25,289+109.8% | Added |
| UBS Group AG | 46,553 | $1.37M | 0.00% | +43,076+1,238.9% | Added |
| Alps Advisors Inc | 43,656 | $1.28M | 0.01% | −1,256−2.8% | Reduced |
| Tudor Investment Corp Et Al | 37,564 | $1.10M | 0.02% | +1,567+4.4% | Added |
| Citigroup Inc | 33,126 | $971.9K | 0.00% | +23,403+240.7% | Added |
| Qube Research & Technologies Ltd | 31,725 | $930.8K | 0.01% | +31,725 | New |
| Deutsche Bank AG | 31,320 | $918.9K | 0.00% | +9,359+42.6% | Added |
| DekaBank Deutsche Girozentrale | 33,000 | $914.0K | 0.00% | +33,000 | New |
| Dynamic Technology Lab Private Ltd | 30,857 | $906.0K | 0.08% | +30,857 | New |
| Susquehanna International Group, LLP | 30,610 | $898.1K | 0.00% | +30,610 | New |
| Seven Eight Capital, LP | 30,053 | $881.8K | 0.18% | +15,115+101.2% | Added |
| Pentwater Capital Management LP | 30,000 | $880.2K | 0.01% | −5,000−14.3% | Reduced |
| First Trust Advisors LP | 27,317 | $801.5K | 0.00% | −29,503−51.9% | Reduced |
| Legal & General Group Plc | 27,052 | $793.7K | 0.00% | +22,029+438.6% | Added |
| New York State Common Retirement Fund | 26,731 | $784.3K | 0.00% | −6,972−20.7% | Reduced |
| MetLife Investment Management | 26,712 | $783.7K | 0.01% | 00.0% | Unchanged |
| Jackson Creek Investment Advisors LLC | 25,246 | $741.0K | 0.31% | +25,246 | New |
| American International Group, Inc. | 24,338 | $714.1K | 0.00% | +485+2.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 23,464 | $688.4K | 0.00% | −43−0.2% | Reduced |
| Engineers Gate Manager LP | 23,122 | $678.4K | 0.03% | +23,122 | New |
| Invesco Ltd. | 22,937 | $673.0K | 0.00% | −192,533−89.4% | Reduced |
| Price T Rowe Associates Inc | 22,507 | $661.0K | 0.00% | +6,824+43.5% | Added |
| Wells Fargo & Company | 21,950 | $644.0K | 0.00% | +20,231+1,176.9% | Added |
| Parsons Capital Management Inc | 21,945 | $643.9K | 0.05% | −5,200−19.2% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 20,421 | $599.0K | 0.04% | +3,465+20.4% | Added |
| Manufacturers Life Insurance Company, The | 20,219 | $593.2K | 0.00% | +83+0.4% | Added |
| California State Teachers Retirement System | 18,762 | $550.5K | 0.00% | −1,369−6.8% | Reduced |
| Brown Advisory Inc | 18,461 | $541.6K | 0.00% | −14,980−44.8% | Reduced |
| Virtu Financial LLC | 18,261 | $536.0K | 0.06% | +18,261 | New |
| Bayesian Capital Management, LP | 16,350 | $479.7K | 0.06% | +1,650+11.2% | Added |
| Principal Financial Group Inc | 14,997 | $440.0K | 0.00% | +1,484+11.0% | Added |
| XTX Topco Ltd | 14,751 | $432.8K | 0.09% | +14,751 | New |
| Profund Advisors LLC | 12,939 | $379.6K | 0.02% | +12,939 | New |
| Kula Investments, LLC | 12,507 | $367.0K | 0.09% | +12,507 | New |