Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q3 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 170
- +18 vs. Q2 2023
- Shares held
- 58.9M
- +5.09M (+9.5%) vs. Q2 2023
- Total value
- $1.08B
- −$82.5M (−7.1%) vs. Q2 2023
- New holders
- 34
- 68 more added
- Sold out
- 16
- 48 more reduced
2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 5,050,080 | $92.5M | 0.00% | +124,188+2.5% | Added |
| BlackRock Inc. | 3,575,459 | $65.5M | 0.00% | +70,174+2.0% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $54.2M | 0.22% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 2,688,873 | $49.2M | 1.66% | −2,185,046−44.8% | Reduced |
| Stonepine Capital Management, LLC | 2,515,868 | $46.1M | 15.30% | +1,394,840+124.4% | Added |
| Millennium Management LLC | 2,119,535 | $38.8M | 0.04% | +197,904+10.3% | Added |
| Boxer Capital, LLC | 2,084,000 | $38.2M | 2.03% | 00.0% | Unchanged |
| Avidity Partners Management LP | 1,756,940 | $32.2M | 1.30% | +855,540+94.9% | Added |
| Adage Capital Partners GP, L.L.C. | 1,700,200 | $31.1M | 0.07% | +932,000+121.3% | Added |
| Rock Springs Capital Management LP | 1,545,016 | $28.3M | 0.76% | +4000.0% | Added |
| Deep Track Capital, LP | 1,259,335 | $23.1M | 0.89% | +1,259,335 | New |
| State Street Corp | 1,239,753 | $22.7M | 0.00% | +82,054+7.1% | Added |
| Citadel Advisors LLC | 1,226,944 | $22.5M | 0.02% | +413,619+50.9% | Added |
| Marshall Wace, LLP | 1,197,760 | $21.9M | 0.05% | −782,420−39.5% | Reduced |
| Goldman Sachs Group Inc | 1,187,128 | $21.7M | 0.01% | −163,350−12.1% | Reduced |
| Samlyn Capital, LLC | 1,164,897 | $21.3M | 0.38% | +1,164,897 | New |
| Voya Investment Management LLC | 1,145,788 | $21.0M | 0.02% | +208,248+22.2% | Added |
| Eventide Asset Management, LLC | 1,116,837 | $20.4M | 0.37% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 1,000,351 | $18.3M | 0.01% | +447,277+80.9% | Added |
| Geode Capital Management, LLC | 982,068 | $18.0M | 0.00% | +44,071+4.7% | Added |
| Morgan Stanley | 952,119 | $17.4M | 0.00% | −99,727−9.5% | Reduced |
| Woodline Partners LP | 899,300 | $16.5M | 0.19% | 00.0% | Unchanged |
| Saturn V Capital Management LLC | 886,143 | $16.2M | 6.79% | +886,143 | New |
| Falcon Edge Capital, LP | 853,262 | $15.6M | 9.88% | 00.0% | Unchanged |
| Emerald Advisers, LLC | 838,572 | $15.4M | 0.74% | +6,764+0.8% | Added |
| D. E. Shaw & Co., Inc. | 760,290 | $13.9M | 0.02% | −829,754−52.2% | Reduced |
| Balyasny Asset Management LLC | 696,881 | $12.8M | 0.04% | −476,972−40.6% | Reduced |
| Octagon Capital Advisors LP | 695,000 | $12.7M | 2.24% | +695,000 | New |
| Gilder Gagnon Howe & Co LLC | 688,438 | $12.6M | 0.19% | +688,438 | New |
| Hudson Bay Capital Management LP | 682,223 | $12.5M | 0.12% | +391,323+134.5% | Added |
| Emerald Mutual Fund Advisers Trust | 681,310 | $12.5M | 0.75% | +1,275+0.2% | Added |
| Jupiter Asset Management Ltd | 649,736 | $11.9M | 0.13% | +649,736 | New |
| Franklin Resources Inc | 617,867 | $11.3M | 0.01% | +589,381+2,069.0% | Added |
| Jane Street Group, LLC | 601,288 | $11.0M | 0.02% | +127,895+27.0% | Added |
| GMT Capital Corp | 576,300 | $10.6M | 0.40% | +115,300+25.0% | Added |
| ExodusPoint Capital Management, LP | 574,623 | $10.5M | 0.13% | +61,532+12.0% | Added |
| Altium Capital Management LP | 534,700 | $9.79M | 5.67% | +349,700+189.0% | Added |
| FMR LLC | 438,686 | $8.03M | 0.00% | −10,296−2.3% | Reduced |
| Northern Trust Corp | 425,778 | $7.80M | 0.00% | −59,640−12.3% | Reduced |
| Nantahala Capital Management, LLC | 407,205 | $7.46M | 0.95% | +242,705+147.5% | Added |
| Charles Schwab Investment Management Inc | 365,862 | $6.70M | 0.00% | +40,380+12.4% | Added |
| Federated Hermes, Inc. | 324,260 | $5.94M | 0.02% | −1,204,740−78.8% | Reduced |
| Primecap Management Co | 304,900 | $5.58M | 0.00% | +304,900 | New |
| International Biotechnology Trust PLC | 295,000 | $5.40M | 1.82% | +270,000+1,080.0% | Added |
| Tri Locum Partners LP | 282,862 | $5.18M | 1.66% | +282,862 | New |
| Ally Bridge Group (NY) LLC | 272,690 | $4.99M | 5.86% | +272,690 | New |
| Voloridge Investment Management, LLC | 268,967 | $4.92M | 0.02% | +154,338+134.6% | Added |
| Verition Fund Management LLC | 267,694 | $4.90M | 0.07% | +46,561+21.1% | Added |
| Susquehanna International Group, LLP | 216,754 | $3.97M | 0.01% | +193,751+842.3% | Added |
| Ghost Tree Capital, LLC | 215,000 | $3.94M | 1.91% | −335,000−60.9% | Reduced |
| Cubist Systematic Strategies, LLC | 200,190 | $3.67M | 0.05% | +145,942+269.0% | Added |
| Sphera Funds Management Ltd. | 193,650 | $3.55M | 0.85% | +93,650+93.7% | Added |
| J. Goldman & Co LP | 184,907 | $3.39M | 0.17% | +85,567+86.1% | Added |
| Oberweis Asset Management Inc | 170,000 | $3.11M | 0.33% | +85,000+100.0% | Added |
| Bank of New York Mellon Corp | 163,595 | $3.00M | 0.00% | −286−0.2% | Reduced |
| Qube Research & Technologies Ltd | 162,710 | $2.98M | 0.01% | +38,530+31.0% | Added |
| Algert Global LLC | 161,405 | $2.96M | 0.14% | +161,405 | New |
| Renaissance Technologies LLC | 150,100 | $2.75M | 0.00% | +150,100 | New |
| AlphaCentric Advisors LLC | 145,500 | $2.66M | 1.51% | +37,500+34.7% | Added |
| Schonfeld Strategic Advisors LLC | 137,523 | $2.52M | 0.02% | −72,862−34.6% | Reduced |
| Ameriprise Financial Inc | 129,918 | $2.38M | 0.00% | −254−0.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 124,455 | $2.28M | 0.01% | +124,455 | New |
| DAFNA Capital Management LLC | 122,547 | $2.24M | 0.70% | +122,547 | New |
| Healthcare of Ontario Pension Plan Trust Fund | 122,130 | $2.24M | 0.01% | −45,000−26.9% | Reduced |
| Alyeska Investment Group, L.P. | 120,157 | $2.20M | 0.02% | −200,000−62.5% | Reduced |
| Walleye Capital LLC | 100,959 | $1.85M | 0.03% | +48,581+92.8% | Added |
| Dark Forest Capital Management LP | 100,156 | $1.83M | 0.15% | +60,108+150.1% | Added |
| JPMorgan Chase & Co | 90,965 | $1.67M | 0.00% | −99,331−52.2% | Reduced |
| Caption Management, LLC | 89,256 | $1.63M | 0.21% | +52,256+141.2% | Added |
| Twinbeech Capital LP | 81,584 | $1.49M | 0.03% | −74,464−47.7% | Reduced |
| Bank of America Corp | 78,186 | $1.43M | 0.00% | −39,025−33.3% | Reduced |
| Sectoral Asset Management Inc | 73,655 | $1.35M | 0.26% | −313,655−81.0% | Reduced |
| Rhumbline Advisers | 68,960 | $1.26M | 0.00% | +865+1.3% | Added |
| Swiss National Bank | 66,500 | $1.22M | 0.00% | +1,100+1.7% | Added |
| Aigen Investment Management, LP | 65,863 | $1.21M | 0.23% | +32,805+99.2% | Added |
| Seven Eight Capital, LP | 59,891 | $1.10M | 0.13% | +59,891 | New |
| Graham Capital Management, L.P. | 56,241 | $1.03M | 0.03% | +25,689+84.1% | Added |
| Alliancebernstein L.P. | 51,542 | $943.7K | 0.00% | 00.0% | Unchanged |
| Legacy Advisors, LLC | 50,000 | $915.5K | 0.15% | +50,000 | New |
| Alps Advisors Inc | 49,696 | $909.9K | 0.01% | +316+0.6% | Added |
| Hennion & Walsh Asset Management, Inc. | 49,566 | $907.6K | 0.06% | +14,427+41.1% | Added |
| Mariner, LLC | 48,625 | $890.3K | 0.00% | −170.0% | Reduced |
| Cornercap Investment Counsel Inc | 47,134 | $863.0K | 0.16% | −9,176−16.3% | Reduced |
| Moore Capital Management, LP | 47,078 | $862.0K | 0.02% | +47,078 | New |
| Putnam Investments LLC | 46,460 | $850.7K | 0.00% | −402−0.9% | Reduced |
| Wells Fargo & Company | 45,341 | $830.2K | 0.00% | −12,154−21.1% | Reduced |
| Citigroup Inc | 43,789 | $801.8K | 0.00% | −33,780−43.5% | Reduced |
| Janney Montgomery Scott LLC | 42,784 | $783.0K | 0.00% | +42,784 | New |
| Gsa Capital Partners LLP | 42,435 | $777.0K | 0.07% | +28,431+203.0% | Added |
| Squarepoint Ops LLC | 40,000 | $732.4K | 0.00% | −5,810−12.7% | Reduced |
| California State Teachers Retirement System | 37,919 | $694.3K | 0.00% | −5,388−12.4% | Reduced |
| Dynamic Technology Lab Private Ltd | 37,494 | $687.0K | 0.07% | +37,494 | New |
| Group One Trading, L.P. | 37,371 | $684.3K | 0.03% | +35,489+1,885.7% | Added |
| UBS Oconnor LLC | 35,000 | $640.9K | 0.01% | −4,000−10.3% | Reduced |
| Credit Suisse AG | 34,313 | $628.3K | 0.00% | +996+3.0% | Added |
| DekaBank Deutsche Girozentrale | 33,000 | $610.0K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 33,030 | $604.8K | 0.00% | −483−1.4% | Reduced |
| Legal & General Group Plc | 32,102 | $587.8K | 0.00% | +3,586+12.6% | Added |
| Polar Asset Management Partners Inc. | 32,000 | $585.9K | 0.01% | −45,000−58.4% | Reduced |
| Invesco Ltd. | 29,835 | $546.3K | 0.00% | +3,095+11.6% | Added |