Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 133
- +39 vs. Q3 2022
- Shares held
- 48.6M
- +11.3M (+30.3%) vs. Q3 2022
- Total value
- $1.79B
- +$748.1M (+71.6%) vs. Q3 2022
- New holders
- 47
- 49 more added
- Sold out
- 8
- 32 more reduced
1 institution that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 6,088,333 | $225.0M | 6.48% | +616,300+11.3% | Added |
| Viking Global Investors LPSuperinvestorViking Global Investors | 4,634,606 | $171.2M | 0.86% | −1,135,930−19.7% | Reduced |
| Vanguard Group Inc | 4,358,492 | $161.0M | 0.00% | +844,136+24.0% | Added |
| BlackRock Inc. | 3,616,926 | $133.6M | 0.00% | +1,321,092+57.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 2,693,000 | $99.5M | 2.06% | +2,693,000 | New |
| Point72 Asset Management, L.P. | 2,127,960 | $78.6M | 0.30% | +1,660,999+355.7% | Added |
| Boxer Capital, LLC | 2,084,000 | $77.0M | 4.14% | 00.0% | Unchanged |
| Adage Capital Partners GP, L.L.C. | 1,909,201 | $70.5M | 0.17% | +559,201+41.4% | Added |
| Federated Hermes, Inc. | 1,614,845 | $59.7M | 0.17% | +285,845+21.5% | Added |
| D. E. Shaw & Co., Inc. | 1,383,732 | $51.1M | 0.09% | +1,221,467+752.8% | Added |
| Rock Springs Capital Management LP | 1,229,637 | $45.4M | 1.09% | +825,900+204.6% | Added |
| Pictet Asset Management SA | 1,121,765 | $41.4M | 0.06% | +1,121,765 | New |
| State Street Corp | 1,075,612 | $39.7M | 0.00% | +248,544+30.1% | Added |
| Goldman Sachs Group Inc | 1,036,270 | $38.3M | 0.01% | +656,871+173.1% | Added |
| Millennium Management LLC | 859,415 | $31.8M | 0.04% | −61,713−6.7% | Reduced |
| Geode Capital Management, LLC | 853,913 | $31.6M | 0.00% | +218,357+34.4% | Added |
| Emerald Advisers, LLC | 836,909 | $30.9M | 1.49% | +235,683+39.2% | Added |
| Falcon Edge Capital, LP | 821,220 | $30.3M | 5.54% | +120,585+17.2% | Added |
| Emerald Mutual Fund Advisers Trust | 655,015 | $24.2M | 1.50% | +183,128+38.8% | Added |
| Balyasny Asset Management LLC | 645,553 | $23.9M | 0.08% | +454,219+237.4% | Added |
| Avoro Capital Advisors LLC | 630,000 | $23.3M | 0.35% | −20,000−3.1% | Reduced |
| Nuveen Asset Management, LLC | 596,054 | $22.0M | 0.01% | +239,367+67.1% | Added |
| Cormorant Asset Management, LP | 550,000 | $20.3M | 1.37% | −60,000−9.8% | Reduced |
| Woodline Partners LP | 508,353 | $18.8M | 0.26% | −512,031−50.2% | Reduced |
| Morgan Stanley | 484,469 | $17.9M | 0.00% | +215,399+80.1% | Added |
| Northern Trust Corp | 395,139 | $14.6M | 0.00% | +109,331+38.3% | Added |
| Ghost Tree Capital, LLC | 350,000 | $12.9M | 5.52% | −200,000−36.4% | Reduced |
| Charles Schwab Investment Management Inc | 317,719 | $11.7M | 0.00% | +76,980+32.0% | Added |
| Voloridge Investment Management, LLC | 295,267 | $10.9M | 0.06% | −86,945−22.7% | Reduced |
| Allspring Global Investments Holdings, LLC | 266,019 | $9.83M | 0.02% | −3,479−1.3% | Reduced |
| Verition Fund Management LLC | 260,551 | $9.63M | 0.19% | −51,865−16.6% | Reduced |
| Eventide Asset Management, LLC | 250,000 | $9.24M | 0.18% | +250,000 | New |
| Iron Triangle Partners LP | 240,240 | $8.88M | 1.59% | +240,240 | New |
| Invesco Ltd. | 215,470 | $7.96M | 0.00% | −46,066−17.6% | Reduced |
| Bank of New York Mellon Corp | 210,139 | $7.76M | 0.00% | +93,195+79.7% | Added |
| Ameriprise Financial Inc | 204,076 | $7.54M | 0.00% | +136,201+200.7% | Added |
| ExodusPoint Capital Management, LP | 203,937 | $7.54M | 0.12% | +141,718+227.8% | Added |
| Great Point Partners LLC | 190,000 | $7.02M | 1.45% | +190,000 | New |
| Renaissance Technologies LLC | 178,300 | $6.59M | 0.01% | +178,300 | New |
| Sectoral Asset Management Inc | 157,950 | $5.84M | 1.13% | −47,450−23.1% | Reduced |
| Maven Securities LTD | 150,000 | $5.54M | 1.11% | +150,000 | New |
| Altium Capital Management LP | 140,000 | $5.17M | 2.65% | +105,000+300.0% | Added |
| Jane Street Group, LLC | 136,557 | $5.05M | 0.01% | +136,557 | New |
| Schonfeld Strategic Advisors LLC | 111,924 | $4.14M | 0.03% | −213,776−65.6% | Reduced |
| Tang Capital Management LLC | 100,000 | $3.69M | 0.54% | +100,000 | New |
| Norges Bank | 81,200 | $3.00M | 0.00% | +81,200 | New |
| Rhumbline Advisers | 71,564 | $2.64M | 0.00% | +25,771+56.3% | Added |
| Wellington Management Group LLP | 67,905 | $2.51M | 0.00% | +67,905 | New |
| EAM Investors, LLC | 65,272 | $2.41M | 0.50% | +65,272 | New |
| Bank of America Corp | 63,366 | $2.34M | 0.00% | +54,479+613.0% | Added |
| First Trust Advisors LP | 56,820 | $2.10M | 0.00% | +56,820 | New |
| Citadel Advisors LLC | 56,757 | $2.10M | 0.00% | −750,073−93.0% | Reduced |
| Soleus Capital Management, L.P. | 50,636 | $1.87M | 0.27% | −378,700−88.2% | Reduced |
| Alyeska Investment Group, L.P. | 50,000 | $1.85M | 0.02% | +50,000 | New |
| JPMorgan Chase & Co | 49,701 | $1.84M | 0.00% | +30,437+158.0% | Added |
| EAM Global Investors LLC | 45,750 | $1.69M | 0.44% | +45,750 | New |
| J. Goldman & Co LP | 45,642 | $1.69M | 0.12% | +45,642 | New |
| Alps Advisors Inc | 44,912 | $1.66M | 0.01% | +44,912 | New |
| Voya Investment Management LLC | 42,146 | $1.56M | 0.00% | +28,611+211.4% | Added |
| Squarepoint Ops LLC | 40,000 | $1.48M | 0.01% | −1,792−4.3% | Reduced |
| Prescott Group Capital Management, L.L.C. | 40,000 | $1.48M | 0.32% | +4,996+14.3% | Added |
| Barclays PLC | 38,495 | $1.42M | 0.00% | +19,695+104.8% | Added |
| Moody Aldrich Partners LLC | 38,064 | $1.41M | 0.28% | +38,064 | New |
| Mariner, LLC | 37,991 | $1.40M | 0.00% | +37,991 | New |
| Alliancebernstein L.P. | 36,242 | $1.34M | 0.00% | 00.0% | Unchanged |
| Tudor Investment Corp Et Al | 35,997 | $1.33M | 0.03% | +19,859+123.1% | Added |
| Pentwater Capital Management LP | 35,000 | $1.29M | 0.04% | +35,000 | New |
| New York State Common Retirement Fund | 33,703 | $1.25M | 0.00% | +10,297+44.0% | Added |
| Brown Advisory Inc | 33,441 | $1.24M | 0.00% | −10,000−23.0% | Reduced |
| Parsons Capital Management Inc | 27,145 | $1.00M | 0.08% | +10,280+61.0% | Added |
| MetLife Investment Management | 26,712 | $987.0K | 0.01% | +7,251+37.3% | Added |
| Group One Trading, L.P. | 25,538 | $943.6K | 0.03% | −63,447−71.3% | Reduced |
| Simplex Trading, LLC | 24,248 | $895.0K | 0.04% | −92,356−79.2% | Reduced |
| Artia Global Partners LP | 23,883 | $882.5K | 0.34% | +23,883 | New |
| American International Group, Inc. | 23,853 | $881.4K | 0.01% | +7,117+42.5% | Added |
| Mirae Asset Global Investments Co., Ltd. | 23,507 | $868.6K | 0.00% | +8,622+57.9% | Added |
| Putnam Investments LLC | 23,032 | $851.0K | 0.00% | −13−0.1% | Reduced |
| Deutsche Bank AG | 21,961 | $811.5K | 0.00% | +6,977+46.6% | Added |
| Manufacturers Life Insurance Company, The | 20,136 | $744.0K | 0.00% | +20,136 | New |
| California State Teachers Retirement System | 20,131 | $743.8K | 0.00% | +6,208+44.6% | Added |
| Walleye Capital LLC | 17,492 | $646.3K | 0.01% | −44,390−71.7% | Reduced |
| Hennion & Walsh Asset Management, Inc. | 16,956 | $627.0K | 0.04% | +16,956 | New |
| Oversea-Chinese Banking CORP Ltd | 16,785 | $620.0K | 0.04% | +16,785 | New |
| Price T Rowe Associates Inc | 15,683 | $579.0K | 0.00% | +15,683 | New |
| Seven Eight Capital, LP | 14,938 | $552.0K | 0.14% | +2,876+23.8% | Added |
| Bayesian Capital Management, LP | 14,700 | $543.2K | 0.08% | +14,700 | New |
| SEI Investments Co | 13,777 | $509.1K | 0.00% | −49,897−78.4% | Reduced |
| Principal Financial Group Inc | 13,513 | $499.3K | 0.00% | +13,513 | New |
| Kestra Advisory Services, LLC | 12,936 | $478.0K | 0.00% | −29,747−69.7% | Reduced |
| Integrated Wealth Concepts LLC | 12,368 | $457.0K | 0.01% | +12,368 | New |
| ProShare Advisors LLC | 11,968 | $442.2K | 0.00% | +11,968 | New |
| SG Americas Securities, LLC | 10,489 | $388.0K | 0.01% | +10,489 | New |
| Fred Alger Management, LLC | 10,092 | $372.9K | 0.00% | −2,750−21.4% | Reduced |
| Citigroup Inc | 9,723 | $359.3K | 0.00% | +1,002+11.5% | Added |
| Cheyne Capital Management (UK) LLP | 9,499 | $351.0K | 0.62% | +9,499 | New |
| State Board of Administration of Florida Retirement System | 8,310 | $307.1K | 0.00% | +8,310 | New |
| Virtus ETF Advisers LLC | 8,307 | $306.9K | 0.16% | +8,307 | New |
| FMR LLC | 7,804 | $288.4K | 0.00% | +7,468+2,222.6% | Added |
| Belvedere Trading LLC | 7,642 | $282.4K | 0.16% | −35,857−82.4% | Reduced |
| Amalgamated Bank | 7,025 | $260.0K | 0.00% | +2,247+47.0% | Added |