Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q3 2024
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 110
- −8 vs. Q2 2024
- Shares held
- 43.5M
- +2.49M (+6.1%) vs. Q2 2024
- Total value
- $140.8M
- +$62.9M (+80.8%) vs. Q2 2024
- New holders
- 23
- 32 more added
- Sold out
- 31
- 35 more reduced
1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TCG Crossover Management, LLC | 4,643,812 | $15.0M | 1.27% | +4,643,812 | New |
| Vanguard Group Inc | 3,089,645 | $10.0M | 0.00% | −1,134,323−26.9% | Reduced |
| BlackRock, Inc. | 2,548,206 | $8.26M | 0.00% | +2,548,206 | New |
| Perceptive Advisors LLC | 2,125,649 | $6.89M | 0.15% | +2,125,649 | New |
| Alyeska Investment Group, L.P. | 2,023,420 | $6.56M | 0.03% | +200,000+11.0% | Added |
| 683 Capital Management, LLC | 2,000,000 | $6.48M | 0.66% | +498,129+33.2% | Added |
| Almitas Capital LLC | 1,988,563 | $6.44M | 2.28% | +84,712+4.4% | Added |
| Standard Life Aberdeen plc | 1,972,242 | $6.39M | 0.01% | +1,853,995+1,567.9% | Added |
| Citadel Advisors LLC | 1,899,560 | $6.15M | 0.01% | +554,742+41.3% | Added |
| Acadian Asset Management LLC | 1,770,197 | $5.73M | 0.02% | +558,580+46.1% | Added |
| Goldman Sachs Group Inc | 1,613,863 | $5.23M | 0.00% | −996,557−38.2% | Reduced |
| Nantahala Capital Management, LLC | 1,404,564 | $4.55M | 0.38% | +1,404,564 | New |
| Farallon Capital Management, L.L.C. | 1,150,221 | $3.73M | 0.02% | 00.0% | Unchanged |
| Bank of America Corp | 912,515 | $2.96M | 0.00% | +434,991+91.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 880,745 | $2.85M | 0.01% | +258,818+41.6% | Added |
| D. E. Shaw & Co., Inc. | 691,066 | $2.24M | 0.00% | −617,115−47.2% | Reduced |
| Walleye Capital LLC | 670,594 | $2.17M | 0.02% | +608,874+986.5% | Added |
| Falcon Edge Capital, LP | 669,487 | $2.17M | 0.67% | +669,487 | New |
| AQR Capital Management LLC | 649,079 | $2.10M | 0.00% | −2,691,864−80.6% | Reduced |
| Citigroup Inc | 575,005 | $1.86M | 0.00% | −88,371−13.3% | Reduced |
| Deutsche Bank AG | 570,857 | $1.85M | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 551,039 | $1.79M | 0.00% | +82,173+17.5% | Added |
| Jacobs Levy Equity Management, Inc | 478,440 | $1.55M | 0.01% | −110,671−18.8% | Reduced |
| Morgan Stanley | 478,265 | $1.55M | 0.00% | −446,194−48.3% | Reduced |
| Millennium Management LLC | 456,816 | $1.48M | 0.00% | −1,078,362−70.2% | Reduced |
| Susquehanna International Group, LLP | 406,157 | $1.32M | 0.00% | −39,881−8.9% | Reduced |
| Two Sigma Investments, LP | 367,237 | $1.19M | 0.00% | −930,601−71.7% | Reduced |
| Jane Street Group, LLC | 344,173 | $1.12M | 0.00% | −146,934−29.9% | Reduced |
| Ghost Tree Capital, LLC | 325,000 | $1.05M | 0.36% | +325,000 | New |
| Two Sigma Advisers, LP | 309,500 | $1.00M | 0.00% | −844,700−73.2% | Reduced |
| Charles Schwab Investment Management Inc | 302,270 | $979.4K | 0.00% | −219,349−42.1% | Reduced |
| Marshall Wace, LLP | 283,986 | $920.1K | 0.00% | +283,986 | New |
| Ikarian Capital, LLC | 274,551 | $889.5K | 0.28% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 271,800 | $880.6K | 0.00% | −539,688−66.5% | Reduced |
| Aldebaran Capital, LLC | 269,803 | $874.2K | 0.80% | 00.0% | Unchanged |
| UBS Group AG | 229,076 | $742.2K | 0.00% | +198,937+660.1% | Added |
| First Trust Advisors LP | 221,626 | $718.1K | 0.00% | +82,529+59.3% | Added |
| FMR LLC | 221,001 | $716.0K | 0.00% | +164,622+292.0% | Added |
| ADAR1 Capital Management, LLC | 220,906 | $715.7K | 0.12% | +113,600+105.9% | Added |
| Panagora Asset Management Inc | 188,465 | $610.6K | 0.00% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 186,286 | $603.6K | 0.00% | +7,512+4.2% | Added |
| Qube Research & Technologies Ltd | 183,894 | $595.8K | 0.00% | −605,233−76.7% | Reduced |
| Schonfeld Strategic Advisors LLC | 166,429 | $539.2K | 0.00% | +144,829+670.5% | Added |
| State Street Corp | 154,908 | $501.9K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 140,559 | $455.4K | 0.00% | +83,048+144.4% | Added |
| Bank of Montreal | 143,512 | $442.0K | 0.00% | +38,263+36.4% | Added |
| Man Group plc | 130,862 | $424.0K | 0.00% | +14,733+12.7% | Added |
| Bridgeway Capital Management, LLC | 130,000 | $421.2K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 129,290 | $418.9K | 0.02% | −159,991−55.3% | Reduced |
| Shay Capital LLC | 117,328 | $380.1K | 0.11% | +117,328 | New |
| Hennion & Walsh Asset Management, Inc. | 114,534 | $371.1K | 0.02% | −4,449−3.7% | Reduced |
| Simplex Trading, LLC | 111,728 | $361.0K | 0.01% | −108,789−49.3% | Reduced |
| Algert Global LLC | 106,219 | $344.1K | 0.01% | +81,405+328.1% | Added |
| Tang Capital Management LLC | 100,000 | $324.0K | 0.02% | 00.0% | Unchanged |
| Northern Trust Corp | 95,350 | $308.9K | 0.00% | −271,899−74.0% | Reduced |
| Boothbay Fund Management, LLC | 85,477 | $276.9K | 0.01% | 00.0% | Unchanged |
| Barclays PLC | 84,572 | $274.0K | 0.00% | +40,319+91.1% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 83,563 | $270.7K | 0.05% | +1,521+1.9% | Added |
| HRT Financial LP | 81,291 | $263.0K | 0.00% | +51,748+175.2% | Added |
| Graham Capital Management, L.P. | 67,956 | $220.2K | 0.01% | −253,911−78.9% | Reduced |
| HSBC Holdings PLC | 61,687 | $197.1K | 0.00% | −14,574−19.1% | Reduced |
| Savant Capital, LLC | 57,565 | $186.5K | 0.00% | −38,313−40.0% | Reduced |
| SG Americas Securities, LLC | 57,386 | $186.0K | 0.00% | +1,550+2.8% | Added |
| Mariner, LLC | 56,334 | $182.5K | 0.00% | −1,205−2.1% | Reduced |
| Price T Rowe Associates Inc | 55,600 | $181.0K | 0.00% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 50,903 | $164.9K | 0.00% | +28,016+122.4% | Added |
| Legacy Advisors, LLC | 50,000 | $162.0K | 0.02% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 49,081 | $159.0K | 0.00% | −117,467−70.5% | Reduced |
| Squarepoint Ops LLC | 48,005 | $155.5K | 0.00% | −224,571−82.4% | Reduced |
| XTX Topco Ltd | 47,672 | $154.5K | 0.01% | −162,940−77.4% | Reduced |
| Jefferies Financial Group Inc. | 46,200 | $149.7K | 0.00% | +46,200 | New |
| Marex Group plc | 40,000 | $129.6K | 0.00% | +40,000 | New |
| Mackenzie Financial Corp | 33,240 | $107.7K | 0.00% | −24,683−42.6% | Reduced |
| State of Wyoming | 25,777 | $83.5K | 0.01% | −36,007−58.3% | Reduced |
| Bank of New York Mellon Corp | 23,679 | $76.7K | 0.00% | +23,679 | New |
| Parsons Capital Management Inc | 21,945 | $71.1K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 21,049 | $68.2K | 0.00% | +2,008+10.5% | Added |
| Premier Path Wealth Partners, LLC | 20,265 | $65.7K | 0.01% | +20,265 | New |
| Brown Advisory Inc | 19,950 | $64.6K | 0.00% | −11−0.1% | Reduced |
| Prudential Financial Inc | 19,400 | $62.9K | 0.00% | +19,400 | New |
| JustInvest LLC | 16,592 | $53.8K | 0.00% | +4,851+41.3% | Added |
| Vident Advisory, LLC | 15,572 | $50.5K | 0.00% | +4,729+43.6% | Added |
| Guggenheim Capital LLC | 15,398 | $49.9K | 0.00% | −50−0.3% | Reduced |
| Aries Wealth Management | 15,000 | $48.6K | 0.01% | +15,000 | New |
| Corton Capital Inc. | 13,104 | $42.5K | 0.02% | +13,104 | New |
| China Universal Asset Management Co., Ltd. | 13,094 | $42.4K | 0.00% | +5,104+63.9% | Added |
| Royal Bank of Canada | 11,850 | $38.0K | 0.00% | −5,281−30.8% | Reduced |
| Bayesian Capital Management, LP | 10,700 | $34.7K | 0.00% | +10,700 | New |
| Bank of Nova Scotia | 10,696 | $34.7K | 0.00% | +10,696 | New |
| Atria Wealth Solutions, Inc. | 10,000 | $32.4K | 0.00% | +10,000 | New |
| Tower Research Capital LLC (TRC) | 9,640 | $31.2K | 0.00% | −22,296−69.8% | Reduced |
| Advisors Asset Management, Inc. | 7,653 | $24.8K | 0.00% | −686−8.2% | Reduced |
| Catalyst Funds Management Pty Ltd | 7,500 | $24.3K | 0.01% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 6,989 | $22.6K | 0.00% | −2,130−23.4% | Reduced |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 1,803 | $8.84K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,462 | $7.58K | 0.00% | +432+21.3% | Added |
| SRS Capital Advisors, Inc. | 2,193 | $7.11K | 0.00% | 00.0% | Unchanged |
| nVerses Capital, LLC | 2,100 | $6.80K | 0.00% | +2,100 | New |
| Steward Partners Investment Advisory, LLC | 2,000 | $6.48K | 0.00% | 00.0% | Unchanged |
| Oliver Lagore Vanvalin Investment Group | 1,600 | $5.18K | 0.00% | +1,600 | New |