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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
110
−8 vs. Q2 2024
Shares held
43.5M
+2.49M (+6.1%) vs. Q2 2024
Total value
$140.8M
+$62.9M (+80.8%) vs. Q2 2024
New holders
23
32 more added
Sold out
31
35 more reduced

1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 110 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ3 2024: $140.8M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2024.

Institutions holding AMLX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Salem Investment Counselors Inc55$1790.00%00.0%Unchanged
The PNC Financial Services Group, Inc.96$3110.00%00.0%Unchanged
Point72 Asset Management, L.P.200$6480.00%+200New
Advisor Group Holdings, Inc.215$6960.00%+215New
Wells Fargo & Company300$9720.00%00.0%Unchanged
Daiwa Securities Group Inc.266$1.00K0.00%00.0%Unchanged
Dunhill Financial, LLC600$1.94K0.00%+600New
Nisa Investment Advisors, LLC745$2.41K0.00%+460+161.4%Added
CWM, LLC890$3.00K0.00%−27,753−96.9%Reduced
Ronald Blue Trust, Inc.2,104$4.00K0.00%+1,395+196.8%Added
Oliver Lagore Vanvalin Investment Group1,600$5.18K0.00%+1,600New
Steward Partners Investment Advisory, LLC2,000$6.48K0.00%00.0%Unchanged
nVerses Capital, LLC2,100$6.80K0.00%+2,100New
SRS Capital Advisors, Inc.2,193$7.11K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,462$7.58K0.00%+432+21.3%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$8.84K0.00%00.0%Unchanged
Russell Investments Group, Ltd.6,989$22.6K0.00%−2,130−23.4%Reduced
Catalyst Funds Management Pty Ltd7,500$24.3K0.01%00.0%Unchanged
Advisors Asset Management, Inc.7,653$24.8K0.00%−686−8.2%Reduced
Tower Research Capital LLC (TRC)9,640$31.2K0.00%−22,296−69.8%Reduced
Atria Wealth Solutions, Inc.10,000$32.4K0.00%+10,000New
Bank of Nova Scotia10,696$34.7K0.00%+10,696New
Bayesian Capital Management, LP10,700$34.7K0.00%+10,700New
Royal Bank of Canada11,850$38.0K0.00%−5,281−30.8%Reduced
China Universal Asset Management Co., Ltd.13,094$42.4K0.00%+5,104+63.9%Added
Corton Capital Inc.13,104$42.5K0.02%+13,104New
Aries Wealth Management15,000$48.6K0.01%+15,000New
Guggenheim Capital LLC15,398$49.9K0.00%−50−0.3%Reduced
Vident Advisory, LLC15,572$50.5K0.00%+4,729+43.6%Added
JustInvest LLC16,592$53.8K0.00%+4,851+41.3%Added
Prudential Financial Inc19,400$62.9K0.00%+19,400New
Brown Advisory Inc19,950$64.6K0.00%−11−0.1%Reduced
Premier Path Wealth Partners, LLC20,265$65.7K0.01%+20,265New
American Century Companies Inc21,049$68.2K0.00%+2,008+10.5%Added
Parsons Capital Management Inc21,945$71.1K0.00%00.0%Unchanged
Bank of New York Mellon Corp23,679$76.7K0.00%+23,679New
State of Wyoming25,777$83.5K0.01%−36,007−58.3%Reduced
Mackenzie Financial Corp33,240$107.7K0.00%−24,683−42.6%Reduced
Marex Group plc40,000$129.6K0.00%+40,000New
Jefferies Financial Group Inc.46,200$149.7K0.00%+46,200New
XTX Topco Ltd47,672$154.5K0.01%−162,940−77.4%Reduced
Squarepoint Ops LLC48,005$155.5K0.00%−224,571−82.4%Reduced
Cubist Systematic Strategies, LLC49,081$159.0K0.00%−117,467−70.5%Reduced
Legacy Advisors, LLC50,000$162.0K0.02%00.0%Unchanged
Balyasny Asset Management LLC50,903$164.9K0.00%+28,016+122.4%Added
Price T Rowe Associates Inc55,600$181.0K0.00%00.0%Unchanged
Mariner, LLC56,334$182.5K0.00%−1,205−2.1%Reduced
SG Americas Securities, LLC57,386$186.0K0.00%+1,550+2.8%Added
Savant Capital, LLC57,565$186.5K0.00%−38,313−40.0%Reduced
HSBC Holdings PLC61,687$197.1K0.00%−14,574−19.1%Reduced
Graham Capital Management, L.P.67,956$220.2K0.01%−253,911−78.9%Reduced
HRT Financial LP81,291$263.0K0.00%+51,748+175.2%Added
Point72 Asia (Singapore) Pte. Ltd.83,563$270.7K0.05%+1,521+1.9%Added
Barclays PLC84,572$274.0K0.00%+40,319+91.1%Added
Boothbay Fund Management, LLC85,477$276.9K0.01%00.0%Unchanged
Northern Trust Corp95,350$308.9K0.00%−271,899−74.0%Reduced
Tang Capital Management LLC100,000$324.0K0.02%00.0%Unchanged
Algert Global LLC106,219$344.1K0.01%+81,405+328.1%Added
Simplex Trading, LLC111,728$361.0K0.01%−108,789−49.3%Reduced
Hennion & Walsh Asset Management, Inc.114,534$371.1K0.02%−4,449−3.7%Reduced
Shay Capital LLC117,328$380.1K0.11%+117,328New
Group One Trading, L.P.129,290$418.9K0.02%−159,991−55.3%Reduced
Bridgeway Capital Management, LLC130,000$421.2K0.01%00.0%Unchanged
Man Group plc130,862$424.0K0.00%+14,733+12.7%Added
Bank of Montreal143,512$442.0K0.00%+38,263+36.4%Added
JPMorgan Chase & Co140,559$455.4K0.00%+83,048+144.4%Added
State Street Corp154,908$501.9K0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC166,429$539.2K0.00%+144,829+670.5%Added
Qube Research & Technologies Ltd183,894$595.8K0.00%−605,233−76.7%Reduced
Federated Hermes, Inc.186,286$603.6K0.00%+7,512+4.2%Added
Panagora Asset Management Inc188,465$610.6K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC220,906$715.7K0.12%+113,600+105.9%Added
FMR LLC221,001$716.0K0.00%+164,622+292.0%Added
First Trust Advisors LP221,626$718.1K0.00%+82,529+59.3%Added
UBS Group AG229,076$742.2K0.00%+198,937+660.1%Added
Aldebaran Capital, LLC269,803$874.2K0.80%00.0%Unchanged
Renaissance Technologies LLC271,800$880.6K0.00%−539,688−66.5%Reduced
Ikarian Capital, LLC274,551$889.5K0.28%00.0%Unchanged
Marshall Wace, LLP283,986$920.1K0.00%+283,986New
Charles Schwab Investment Management Inc302,270$979.4K0.00%−219,349−42.1%Reduced
Two Sigma Advisers, LP309,500$1.00M0.00%−844,700−73.2%Reduced
Ghost Tree Capital, LLC325,000$1.05M0.36%+325,000New
Jane Street Group, LLC344,173$1.12M0.00%−146,934−29.9%Reduced
Two Sigma Investments, LP367,237$1.19M0.00%−930,601−71.7%Reduced
Susquehanna International Group, LLP406,157$1.32M0.00%−39,881−8.9%Reduced
Millennium Management LLC456,816$1.48M0.00%−1,078,362−70.2%Reduced
Morgan Stanley478,265$1.55M0.00%−446,194−48.3%Reduced
Jacobs Levy Equity Management, Inc478,440$1.55M0.01%−110,671−18.8%Reduced
Geode Capital Management, LLC551,039$1.79M0.00%+82,173+17.5%Added
Deutsche Bank AG570,857$1.85M0.00%00.0%Unchanged
Citigroup Inc575,005$1.86M0.00%−88,371−13.3%Reduced
AQR Capital Management LLC649,079$2.10M0.00%−2,691,864−80.6%Reduced
Falcon Edge Capital, LP669,487$2.17M0.67%+669,487New
Walleye Capital LLC670,594$2.17M0.02%+608,874+986.5%Added
D. E. Shaw & Co., Inc.691,066$2.24M0.00%−617,115−47.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.880,745$2.85M0.01%+258,818+41.6%Added
Bank of America Corp912,515$2.96M0.00%+434,991+91.1%Added
Farallon Capital Management, L.L.C.1,150,221$3.73M0.02%00.0%Unchanged
Nantahala Capital Management, LLC1,404,564$4.55M0.38%+1,404,564New
Goldman Sachs Group Inc1,613,863$5.23M0.00%−996,557−38.2%Reduced