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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
72
+72 vs. Q4 2021
Shares held
23.4M
+23.4M vs. Q4 2021
Total value
$299.9M
+$299.9M vs. Q4 2021
New holders
72
0 more added
Sold out
0
0 more reduced

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 72 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ1 2022: $299.9M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2021.

Institutions holding AMLX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Viking Global Investors LPSuperinvestorViking Global Investors7,170,536$92.1M0.37%+7,170,536New
Bain Capital Life Sciences Investors, LLC2,756,050$35.4M3.44%+2,756,050New
Boxer Capital, LLC2,200,000$28.3M1.45%+2,200,000New
Perceptive Advisors LLC1,474,107$18.9M0.39%+1,474,107New
Rock Springs Capital Management LP998,307$12.8M0.32%+998,307New
Vanguard Group Inc992,188$12.8M0.00%+992,188New
Verition Fund Management LLC925,353$11.9M0.23%+925,353New
Tybourne Capital Management (HK) Ltd768,603$9.88M0.58%+768,603New
Falcon Edge Capital, LP617,220$7.93M0.71%+617,220New
683 Capital Management, LLC677,714$7.68M0.45%+677,714New
Marshall Wace, LLP584,464$7.51M0.02%+584,464New
BlackRock Inc.572,341$7.35M0.00%+572,341New
Citadel Advisors LLC501,636$6.45M0.01%+501,636New
Allspring Global Investments Holdings, LLC402,324$5.17M0.01%+402,324New
Ikarian Capital, LLC396,654$5.10M1.55%+396,654New
Woodline Partners LP390,229$5.01M0.08%+390,229New
Geode Capital Management, LLC190,150$2.44M0.00%+190,150New
Agf Investments Inc.160,000$2.06M0.02%+160,000New
Renaissance Technologies LLC146,400$1.88M0.00%+146,400New
Millennium Management LLC137,241$1.76M0.00%+137,241New
Sofinnova Investments, Inc.100,000$1.28M0.11%+100,000New
State Street Corp99,212$1.27M0.00%+99,212New
Wells Fargo & Company89,824$1.16M0.00%+89,824New
FMR LLC88,125$1.13M0.00%+88,125New
Ameriprise Financial Inc82,310$1.06M0.00%+82,310New
Northern Trust Corp82,170$1.06M0.00%+82,170New
Artal Group S.A.75,000$964.0K0.04%+75,000New
Charles Schwab Investment Management Inc73,027$939.0K0.00%+73,027New
Balyasny Asset Management LLC62,915$808.0K0.00%+62,915New
Oasis Management Co Ltd.50,000$643.0K0.11%+50,000New
Boothbay Fund Management, LLC48,271$620.0K0.02%+48,271New
Susquehanna International Group, LLP46,565$598.0K0.00%+46,565New
Morgan Stanley42,345$544.0K0.00%+42,345New
PFS Investments Inc.39,558$508.0K0.01%+39,558New
Adage Capital Partners GP, L.L.C.37,200$478.0K0.00%+37,200New
Caption Management, LLC36,667$472.0K0.03%+36,667New
Atom Investors LP36,691$471.0K0.22%+36,691New
Cubist Systematic Strategies, LLC34,914$449.0K0.00%+34,914New
Silverarc Capital Management, LLC30,000$386.0K0.21%+30,000New
Jane Street Group, LLC29,246$376.0K0.00%+29,246New
Walleye Capital LLC28,187$362.0K0.01%+28,187New
Bank of New York Mellon Corp26,451$340.0K0.00%+26,451New
Caas Capital Management LP17,000$218.0K0.04%+17,000New
Squarepoint Ops LLC15,000$193.0K0.00%+15,000New
Nuveen Asset Management, LLC13,230$170.0K0.00%+13,230New
Pura Vida Investments, LLC10,000$129.0K0.02%+10,000New
MetLife Investment Management6,785$87.2K0.00%+6,785New
Deutsche Bank AG5,349$69.0K0.00%+5,349New
Simplex Trading, LLC5,198$66.0K0.00%+5,198New
American International Group, Inc.4,760$61.0K0.00%+4,760New
JPMorgan Chase & Co4,497$58.0K0.00%+4,497New
Royal Bank of Canada4,294$56.0K0.00%+4,294New
California State Teachers Retirement System4,086$53.0K0.00%+4,086New
UBS Group AG4,157$53.0K0.00%+4,157New
New York State Common Retirement Fund4,000$51.0K0.00%+4,000New
Bank of America Corp2,904$38.0K0.00%+2,904New
STRS Ohio2,300$29.0K0.00%+2,300New
Quantbot Technologies LP2,200$28.0K0.00%+2,200New
Amalgamated Bank1,763$23.0K0.00%+1,763New
Amalgamated Financial Corp.1,763$23.0K0.00%+1,763New
Barclays PLC1,559$20.0K0.00%+1,559New
Advisor Group Holdings, Inc.1,400$18.0K0.00%+1,400New
Group One Trading, L.P.1,243$16.0K0.00%+1,243New
Citigroup Inc1,154$15.0K0.00%+1,154New
Point72 Hong Kong Ltd1,159$15.0K0.00%+1,159New
Steward Partners Investment Advisory, LLC1,100$14.0K0.00%+1,100New
Legal & General Group Plc905$12.0K0.00%+905New
Metropolitan Life Insurance Co795$10.2K0.00%+795New
Ameritas Investment Partners, Inc.744$10.0K0.00%+744New
Tower Research Capital LLC (TRC)711$10.0K0.00%+711New
High Net Worth Advisory Group LLC500$6.00K0.00%+500New
Northwestern Mutual Wealth Management Co300$4.00K0.00%+300New