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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
95
+17 vs. Q2 2022
Shares held
37.3M
+10.6M (+40.0%) vs. Q2 2022
Total value
$1.05B
+$532.3M (+103.8%) vs. Q2 2022
New holders
33
38 more added
Sold out
16
20 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 95 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ3 2022: $1.05B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2022.

Institutions holding AMLX in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Viking Global Investors LPSuperinvestorViking Global Investors5,770,536$162.4M0.75%−1,400,000−19.5%Reduced
Perceptive Advisors LLC5,472,033$154.0M4.48%+1,931,625+54.6%Added
Vanguard Group Inc3,514,356$98.9M0.00%+2,520,355+253.6%Added
BlackRock Inc.2,295,834$64.6M0.00%+1,586,402+223.6%Added
Boxer Capital, LLC2,084,000$58.7M3.30%−116,000−5.3%Reduced
Adage Capital Partners GP, L.L.C.1,350,000$38.0M0.09%+1,150,000+575.0%Added
Federated Hermes, Inc.1,329,000$37.4M0.11%+1,329,000New
Bain Capital Life Sciences Investors, LLC1,023,214$28.8M3.44%−925,000−47.5%Reduced
Woodline Partners LP1,020,384$28.7M0.42%+630,155+161.5%Added
Millennium Management LLC921,128$25.9M0.03%+475,084+106.5%Added
State Street Corp827,068$23.3M0.00%+630,603+321.0%Added
Citadel Advisors LLC806,830$22.7M0.03%+52,420+6.9%Added
Falcon Edge Capital, LP700,635$19.7M2.33%00.0%Unchanged
Avoro Capital Advisors LLC650,000$18.3M0.34%+650,000New
Geode Capital Management, LLC635,556$17.9M0.00%+404,139+174.6%Added
Cormorant Asset Management, LP610,000$17.2M1.21%+610,000New
Emerald Advisers, LLC601,226$16.9M0.87%+601,226New
Ghost Tree Capital, LLC550,000$15.5M6.32%+550,000New
Emerald Mutual Fund Advisers Trust471,887$13.3M0.84%+471,887New
Point72 Asset Management, L.P.466,961$13.1M0.06%+154,500+49.4%Added
Soleus Capital Management, L.P.429,336$12.1M1.64%+429,336New
Rock Springs Capital Management LP403,737$11.4M0.29%−570,370−58.6%Reduced
Voloridge Investment Management, LLC382,212$10.8M0.06%+382,212New
Goldman Sachs Group Inc379,399$10.7M0.00%+379,399New
Marshall Wace, LLP341,064$9.60M0.02%−317,309−48.2%Reduced
Schonfeld Strategic Advisors LLC325,700$9.17M0.08%+325,700New
Verition Fund Management LLC312,416$8.79M0.12%−637,713−67.1%Reduced
Northern Trust Corp285,808$8.04M0.00%+191,267+202.3%Added
Allspring Global Investments Holdings, LLC269,498$7.59M0.01%−145,800−35.1%Reduced
Morgan Stanley269,070$7.58M0.00%+225,964+524.2%Added
Invesco Ltd.261,536$7.36M0.00%+261,536New
Charles Schwab Investment Management Inc240,739$6.78M0.00%+170,330+241.9%Added
Nuveen Asset Management, LLC356,687$6.38M0.00%+317,200+803.3%Added
Sectoral Asset Management Inc205,400$5.78M1.14%+205,400New
Balyasny Asset Management LLC191,334$5.39M0.02%+191,334New
D. E. Shaw & Co., Inc.162,265$4.57M0.01%+162,265New
Bank of New York Mellon Corp116,944$3.29M0.00%+87,923+303.0%Added
Simplex Trading, LLC116,604$3.28M0.13%−41,486−26.2%Reduced
Group One Trading, L.P.88,985$2.50M0.08%−66,403−42.7%Reduced
Pura Vida Investments, LLC68,652$1.93M0.29%+58,102+550.7%Added
Ameriprise Financial Inc67,875$1.91M0.00%−31,080−31.4%Reduced
SEI Investments Co63,674$1.79M0.00%−30,180−32.2%Reduced
ExodusPoint Capital Management, LP62,219$1.75M0.02%+46,206+288.6%Added
Walleye Capital LLC61,882$1.74M0.04%+61,882New
Belvedere Trading LLC43,499$1.63M1.79%−125,089−74.2%Reduced
Rhumbline Advisers45,793$1.29M0.00%+29,619+183.1%Added
Brown Advisory Inc43,441$1.22M0.00%+43,441New
Caption Management, LLC42,947$1.21M0.21%−26,704−38.3%Reduced
Kestra Advisory Services, LLC42,683$1.20M0.01%+42,683New
Squarepoint Ops LLC41,792$1.18M0.01%+41,792New
Alliancebernstein L.P.36,242$1.02M0.00%+342+1.0%Added
Prescott Group Capital Management, L.L.C.35,004$985.0K0.30%+35,004New
Altium Capital Management LP35,000$985.0K0.37%+35,000New
New York State Common Retirement Fund23,406$659.0K0.00%+14,209+154.5%Added
Putnam Investments LLC23,045$649.0K0.00%+23,045New
MetLife Investment Management19,461$547.8K0.00%+12,676+186.8%Added
JPMorgan Chase & Co19,264$542.0K0.00%+13,132+214.2%Added
Barclays PLC18,800$529.0K0.00%+18,225+3,169.6%Added
Parsons Capital Management Inc16,865$475.0K0.04%+16,865New
American International Group, Inc.16,736$471.0K0.00%+11,368+211.8%Added
Tudor Investment Corp Et Al16,138$454.0K0.01%+16,138New
Deutsche Bank AG14,984$422.0K0.00%+10,292+219.4%Added
Mirae Asset Global Investments Co., Ltd.14,885$419.0K0.00%+14,885New
California State Teachers Retirement System13,923$392.0K0.00%+9,018+183.9%Added
Voya Investment Management LLC13,535$381.0K0.00%+13,535New
Fred Alger Management, LLC12,842$362.0K0.00%+7,713+150.4%Added
Seven Eight Capital, LP12,062$340.0K0.07%+12,062New
Cutler Group LP11,525$324.0K0.04%+3,814+49.5%Added
Susquehanna International Group, LLP10,285$290.0K0.00%−127,944−92.6%Reduced
Bank of America Corp8,887$251.0K0.00%−7,683−46.4%Reduced
Citigroup Inc8,721$245.0K0.00%+7,886+944.4%Added
Amalgamated Bank4,778$135.0K0.00%+3,254+213.5%Added
Cubist Systematic Strategies, LLC4,104$116.0K0.00%−48,896−92.3%Reduced
UBS Group AG3,987$112.0K0.00%+3,810+2,152.5%Added
Legal & General Group Plc3,461$97.0K0.00%+2,237+182.8%Added
Tower Research Capital LLC (TRC)3,058$86.0K0.00%−282−8.4%Reduced
Jefferies Group LLC2,791$78.6K0.00%+2,791New
Ameritas Investment Partners, Inc.2,764$77.0K0.00%+2,020+271.5%Added
Advisor Group Holdings, Inc.2,442$69.0K0.00%+492+25.2%Added
Metropolitan Life Insurance Co2,207$62.1K0.00%+1,412+177.6%Added
High Net Worth Advisory Group LLC2,000$56.0K0.02%+500+33.3%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$51.0K0.00%+1,803New
Royal Bank of Canada1,373$38.0K0.00%+365+36.2%Added
STRS Ohio1,200$33.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,050$30.0K0.00%−50−4.5%Reduced
Wells Fargo & Company957$27.0K0.00%−621−39.4%Reduced
Credit Agricole S A500$14.0K0.00%00.0%Unchanged
Tradition Wealth Management, LLC500$14.0K0.00%00.0%Unchanged
FMR LLC336$9.00K0.00%−122,107−99.7%Reduced
Cowen and Company, LLC20,800$7.00K0.00%+20,800New
Credit Suisse AG197$6.00K0.00%+186+1,690.9%Added
Nisa Investment Advisors, LLC26$1.00K0.00%+26New
Kelly Financial Services LLC33$9290.00%+33New
Ronald Blue Trust, Inc.15$00.00%+15New
Covestor Ltd5$00.00%+5New
Tybourne Capital Management (HK) Ltd0$00.00%−768,603−100.0%Sold out
683 Capital Management, LLC0$00.00%−677,714−100.0%Sold out
Ikarian Capital, LLC0$00.00%−246,554−100.0%Sold out
Sofinnova Investments, Inc.0$00.00%−187,381−100.0%Sold out
Jane Street Group, LLC0$00.00%−179,602−100.0%Sold out