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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
−21 vs. Q1 2024
Shares held
43.6M
−5.84M (−11.8%) vs. Q1 2024
Total value
$82.9M
−$58.4M (−41.3%) vs. Q1 2024
New holders
32
29 more added
Sold out
53
44 more reduced

3 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 119 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ2 2024: $82.9M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q1 2024.

Institutions holding AMLX in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc4,223,968$8.03M0.00%−1,124,171−21.0%Reduced
AQR Capital Management LLC3,340,943$6.35M0.01%+3,224,454+2,768.0%Added
BlackRock Inc.2,669,741$5.07M0.00%−1,804,981−40.3%Reduced
Goldman Sachs Group Inc2,610,420$4.96M0.00%−332,766−11.3%Reduced
Almitas Capital LLC1,903,851$3.62M1.50%+1,903,851New
Alyeska Investment Group, L.P.1,823,420$3.46M0.02%+814,813+80.8%Added
Millennium Management LLC1,535,178$2.92M0.00%−936,277−37.9%Reduced
683 Capital Management, LLC1,501,871$2.85M0.30%+1,501,871New
Boxer Capital, LLC1,500,000$2.85M0.15%00.0%Unchanged
Citadel Advisors LLC1,344,818$2.56M0.00%+14,434+1.1%Added
D. E. Shaw & Co., Inc.1,308,181$2.49M0.00%+265,598+25.5%Added
Two Sigma Investments, LP1,297,838$2.47M0.01%−135,027−9.4%Reduced
Acadian Asset Management LLC1,211,617$2.30M0.01%+1,211,617New
Two Sigma Advisers, LP1,154,200$2.19M0.00%+355,300+44.5%Added
Farallon Capital Management, L.L.C.1,150,221$2.19M0.01%00.0%Unchanged
Morgan Stanley924,459$1.76M0.00%−1,146,194−55.4%Reduced
Renaissance Technologies LLC811,488$1.54M0.00%+106,888+15.2%Added
Qube Research & Technologies Ltd789,127$1.50M0.00%−154,936−16.4%Reduced
Citigroup Inc663,376$1.26M0.00%−251,351−27.5%Reduced
Connor, Clark & Lunn Investment Management Ltd.621,927$1.18M0.00%+95,239+18.1%Added
Jacobs Levy Equity Management, Inc589,111$1.12M0.00%+589,111New
Deutsche Bank AG570,857$1.08M0.00%−185,312−24.5%Reduced
Woodline Partners LP523,772$995.2K0.01%00.0%Unchanged
Charles Schwab Investment Management Inc521,619$991.1K0.00%+85,716+19.7%Added
Jane Street Group, LLC491,107$933.1K0.00%−536,513−52.2%Reduced
Bank of America Corp477,524$907.3K0.00%+201,568+73.0%Added
Geode Capital Management, LLC468,866$891.1K0.00%−597,379−56.0%Reduced
Susquehanna International Group, LLP446,038$847.5K0.00%+199,239+80.7%Added
Northern Trust Corp367,249$697.8K0.00%−58,318−13.7%Reduced
Aviva PLC363,032$689.8K0.00%+217,614+149.6%Added
Graham Capital Management, L.P.321,867$611.5K0.02%−202,760−38.6%Reduced
Sofinnova Investments, Inc.299,691$569.4K0.04%−7,038−2.3%Reduced
Group One Trading, L.P.289,281$549.6K0.02%+66,559+29.9%Added
Ikarian Capital, LLC274,551$521.6K0.16%−56,900−17.2%Reduced
Squarepoint Ops LLC272,576$517.9K0.00%+113,267+71.1%Added
Aldebaran Capital, LLC269,803$512.6K0.48%+269,803New
Hudson Bay Capital Management LP250,000$475.0K0.00%−248,000−49.8%Reduced
Simplex Trading, LLC220,517$418.0K0.01%+138,410+168.6%Added
XTX Topco Ltd210,612$400.2K0.03%+210,612New
Panagora Asset Management Inc188,465$358.1K0.00%−551−0.3%Reduced
Federated Hermes, Inc.178,774$339.7K0.00%+2,791+1.6%Added
Cubist Systematic Strategies, LLC166,548$316.4K0.01%−9,566−5.4%Reduced
State Street Corp154,908$294.3K0.00%−1,905,134−92.5%Reduced
First Trust Advisors LP139,097$264.3K0.00%−31,381−18.4%Reduced
State of Wisconsin Investment Board138,500$263.1K0.00%−223,222−61.7%Reduced
Bridgeway Capital Management, LLC130,000$247.0K0.01%+130,000New
Hennion & Walsh Asset Management, Inc.118,983$226.1K0.01%+6,116+5.4%Added
Standard Life Aberdeen plc118,247$224.7K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd118,105$224.4K0.01%−223,412−65.4%Reduced
Man Group plc116,129$220.6K0.00%+55,450+91.4%Added
LMR Partners LLP113,300$215.3K0.00%+113,300New
Alpine Global Management, LLC108,862$206.8K0.04%+108,862New
ADAR1 Capital Management, LLC107,306$203.9K0.04%+68,448+176.1%Added
Bank of Montreal105,249$202.1K0.00%+105,249New
Tang Capital Management LLC100,000$190.0K0.02%00.0%Unchanged
Maven Securities LTD100,000$190.0K0.03%+75,000+300.0%Added
Savant Capital, LLC95,878$182.2K0.00%+95,878New
Centiva Capital, LP90,733$172.4K0.01%+90,733New
Alps Advisors Inc90,357$171.7K0.00%−48,893−35.1%Reduced
Boothbay Fund Management, LLC85,477$162.4K0.01%−17,300−16.8%Reduced
Engineers Gate Manager LP84,044$159.7K0.00%+84,044New
Point72 Asia (Singapore) Pte. Ltd.82,042$155.9K0.03%+82,042New
HSBC Holdings PLC76,261$149.9K0.00%+27,954+57.9%Added
State of Wyoming61,784$117.4K0.02%+61,784New
Walleye Capital LLC61,720$117.3K0.00%−300,150−82.9%Reduced
Paloma Partners Management Co57,954$110.1K0.01%+57,954New
Mackenzie Financial Corp57,923$110.1K0.00%−14,649−20.2%Reduced
Mariner, LLC57,539$109.3K0.00%+8,271+16.8%Added
JPMorgan Chase & Co57,511$109.3K0.00%−352,248−86.0%Reduced
FMR LLC56,379$107.1K0.00%+36,989+190.8%Added
Price T Rowe Associates Inc55,600$106.0K0.00%−914,955−94.3%Reduced
SG Americas Securities, LLC55,836$106.0K0.00%+29,697+113.6%Added
Legacy Advisors, LLC50,000$95.0K0.01%00.0%Unchanged
Barclays PLC44,253$84.1K0.00%−62,589−58.6%Reduced
Sphera Funds Management Ltd.36,050$68.5K0.01%−231,200−86.5%Reduced
Cerity Partners LLC33,365$63.4K0.00%+33,365New
Tower Research Capital LLC (TRC)31,936$60.7K0.00%+21,640+210.2%Added
UBS Group AG30,139$57.3K0.00%−180,434−85.7%Reduced
HRT Financial LP29,543$56.0K0.00%+29,543New
Allspring Global Investments Holdings, LLC28,785$54.7K0.00%+13,509+88.4%Added
Rhumbline Advisers28,779$54.7K0.00%−40,624−58.5%Reduced
CWM, LLC28,643$54.0K0.00%+14,613+104.2%Added
Mirae Asset Global ETFs Holdings Ltd.26,032$49.5K0.00%+26,032New
Point72 (DIFC) Ltd25,953$49.3K0.00%−23,040−47.0%Reduced
Algert Global LLC24,814$47.1K0.00%+24,814New
Balyasny Asset Management LLC22,887$43.5K0.00%+22,887New
Parsons Capital Management Inc21,945$41.7K0.00%00.0%Unchanged
Schonfeld Strategic Advisors LLC21,600$41.0K0.00%+21,600New
Zuckerman Investment Group, LLC20,000$38.0K0.00%+20,000New
Brown Advisory Inc19,961$37.9K0.00%00.0%Unchanged
American Century Companies Inc19,041$36.2K0.00%−359,757−95.0%Reduced
Jump Financial, LLC17,685$33.6K0.00%+17,685New
Royal Bank of Canada17,131$32.0K0.00%+15,779+1,167.1%Added
Guggenheim Capital LLC15,448$29.4K0.00%−890−5.4%Reduced
JustInvest LLC11,741$22.3K0.00%+11,741New
ProShare Advisors LLC11,000$20.9K0.00%−2,874−20.7%Reduced
Vident Advisory, LLC10,843$20.6K0.00%+10,843New
Teza Capital Management LLC10,160$19.3K0.00%−3,271−24.4%Reduced
Russell Investments Group, Ltd.9,119$17.3K0.00%+8,957+5,529.0%Added
Advisors Asset Management, Inc.8,339$15.8K0.00%−11−0.1%Reduced