Amylyx Pharmaceuticals, Inc.
AMLX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001658551
In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.
13F holders, Q2 2023
Institutional positions in Amylyx Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 154
- +8 vs. Q1 2023
- Shares held
- 54.5M
- +3.18M (+6.2%) vs. Q1 2023
- Total value
- $1.18B
- −$330.2M (−21.9%) vs. Q1 2023
- New holders
- 29
- 66 more added
- Sold out
- 21
- 43 more reduced
1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 206 | $2.07B |
| Q1 2026 | 171 | $1.59B |
| Q4 2025 | 180 | $1.36B |
| Q3 2025 | 169 | $1.49B |
| Q2 2025 | 131 | $523.6M |
| Q1 2025 | 136 | $261.6M |
| Q4 2024 | 122 | $188.3M |
| Q3 2024 | 110 | $140.8M |
| Q2 2024 | 119 | $82.9M |
| Q1 2024 | 143 | $141.5M |
| Q4 2023 | 178 | $887.4M |
| Q3 2023 | 170 | $1.08B |
| Q2 2023 | 154 | $1.18B |
| Q1 2023 | 147 | $1.51B |
| Q4 2022 | 133 | $1.79B |
| Q3 2022 | 95 | $1.05B |
| Q2 2022 | 78 | $512.9M |
| Q1 2022 | 72 | $299.9M |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 4,925,892 | $106.3M | 0.00% | +178,551+3.8% | Added |
| Perceptive Advisors LLC | 4,873,919 | $105.1M | 3.05% | −1,160,725−19.2% | Reduced |
| BlackRock Inc. | 3,505,285 | $75.6M | 0.00% | −109,633−3.0% | Reduced |
| Viking Global Investors LPSuperinvestorViking Global Investors | 2,962,555 | $63.9M | 0.26% | 00.0% | Unchanged |
| Boxer Capital, LLC | 2,084,000 | $45.0M | 2.08% | 00.0% | Unchanged |
| Marshall Wace, LLP | 1,980,180 | $42.7M | 0.09% | +840,940+73.8% | Added |
| Millennium Management LLC | 1,921,631 | $41.4M | 0.04% | +847,021+78.8% | Added |
| D. E. Shaw & Co., Inc. | 1,590,044 | $34.3M | 0.05% | −432,326−21.4% | Reduced |
| Rock Springs Capital Management LP | 1,544,616 | $33.3M | 0.79% | +91,800+6.3% | Added |
| Federated Hermes, Inc. | 1,529,000 | $33.0M | 0.08% | −317,117−17.2% | Reduced |
| Goldman Sachs Group Inc | 1,350,478 | $29.1M | 0.01% | −15,694−1.1% | Reduced |
| Balyasny Asset Management LLC | 1,173,853 | $25.3M | 0.07% | +753,012+178.9% | Added |
| State Street Corp | 1,157,699 | $25.0M | 0.00% | +91,461+8.6% | Added |
| Stonepine Capital Management, LLC | 1,121,028 | $24.2M | 8.72% | +1,121,028 | New |
| Eventide Asset Management, LLC | 1,116,837 | $24.1M | 0.41% | +658,783+143.8% | Added |
| Morgan Stanley | 1,051,846 | $22.7M | 0.00% | +149,299+16.5% | Added |
| Deerfield Management Company, L.P. (Series C) | 1,050,198 | $22.7M | 0.48% | −934,135−47.1% | Reduced |
| Great Point Partners LLC | 968,795 | $20.9M | 4.19% | +185,000+23.6% | Added |
| Geode Capital Management, LLC | 937,997 | $20.2M | 0.00% | +47,015+5.3% | Added |
| Voya Investment Management LLC | 937,540 | $20.2M | 0.02% | +318,510+51.5% | Added |
| Avidity Partners Management LP | 901,400 | $19.4M | 0.68% | +1,400+0.2% | Added |
| Woodline Partners LP | 899,300 | $19.4M | 0.23% | +465,100+107.1% | Added |
| Falcon Edge Capital, LP | 853,262 | $18.4M | 12.06% | −77,075−8.3% | Reduced |
| Emerald Advisers, LLC | 831,808 | $17.9M | 0.79% | −141,027−14.5% | Reduced |
| Citadel Advisors LLC | 813,325 | $17.5M | 0.02% | +584,419+255.3% | Added |
| Adage Capital Partners GP, L.L.C. | 768,200 | $16.6M | 0.04% | −239,136−23.7% | Reduced |
| Emerald Mutual Fund Advisers Trust | 680,035 | $14.7M | 0.80% | −109,556−13.9% | Reduced |
| Pictet Asset Management SA | 601,646 | $13.0M | 0.02% | −832,200−58.0% | Reduced |
| Nuveen Asset Management, LLC | 553,074 | $11.9M | 0.00% | −58,858−9.6% | Reduced |
| Ghost Tree Capital, LLC | 550,000 | $11.9M | 4.28% | +75,000+15.8% | Added |
| ExodusPoint Capital Management, LP | 513,091 | $11.1M | 0.13% | +119,187+30.3% | Added |
| Northern Trust Corp | 485,418 | $10.5M | 0.00% | +21,538+4.6% | Added |
| Jane Street Group, LLC | 473,393 | $10.2M | 0.01% | +208,535+78.7% | Added |
| GMT Capital Corp | 461,000 | $9.94M | 0.38% | +461,000 | New |
| FMR LLC | 448,982 | $9.68M | 0.00% | +441,752+6,110.0% | Added |
| Sectoral Asset Management Inc | 387,310 | $8.35M | 1.39% | +144,910+59.8% | Added |
| Charles Schwab Investment Management Inc | 325,482 | $7.02M | 0.00% | +5,396+1.7% | Added |
| Alyeska Investment Group, L.P. | 320,157 | $6.91M | 0.05% | +68,750+27.3% | Added |
| Hudson Bay Capital Management LP | 290,900 | $6.27M | 0.06% | +290,900 | New |
| Lord, Abbett & Co. LLC | 244,493 | $5.27M | 0.02% | −5,549−2.2% | Reduced |
| Verition Fund Management LLC | 221,133 | $4.77M | 0.07% | −465−0.2% | Reduced |
| Schonfeld Strategic Advisors LLC | 210,385 | $4.54M | 0.04% | −74,620−26.2% | Reduced |
| Deutsche Bank AG | 191,611 | $4.13M | 0.00% | +160,291+511.8% | Added |
| JPMorgan Chase & Co | 190,296 | $4.10M | 0.00% | +88,596+87.1% | Added |
| Altium Capital Management LP | 185,000 | $3.99M | 3.12% | 00.0% | Unchanged |
| Healthcare of Ontario Pension Plan Trust Fund | 167,130 | $3.60M | 0.02% | +167,130 | New |
| Nantahala Capital Management, LLC | 164,500 | $3.55M | 0.43% | +164,500 | New |
| Bank of New York Mellon Corp | 163,881 | $3.53M | 0.00% | −40,775−19.9% | Reduced |
| Twinbeech Capital LP | 156,048 | $3.37M | 0.07% | +24,276+18.4% | Added |
| Jump Financial, LLC | 141,447 | $3.05M | 0.11% | +141,447 | New |
| Ameriprise Financial Inc | 130,172 | $2.81M | 0.00% | −82,281−38.7% | Reduced |
| Qube Research & Technologies Ltd | 124,180 | $2.68M | 0.01% | +92,455+291.4% | Added |
| Soleus Capital Management, L.P. | 120,000 | $2.59M | 0.29% | +56,786+89.8% | Added |
| Bank of America Corp | 117,211 | $2.53M | 0.00% | +48,887+71.6% | Added |
| Voloridge Investment Management, LLC | 114,629 | $2.47M | 0.01% | −20,836−15.4% | Reduced |
| AlphaCentric Advisors LLC | 108,000 | $2.33M | 1.29% | +100,500+1,340.0% | Added |
| Tekla Capital Management LLC | 104,007 | $2.24M | 0.09% | +104,007 | New |
| Tang Capital Management LLC | 100,000 | $2.16M | 0.32% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 100,000 | $2.16M | 0.46% | +100,000 | New |
| J. Goldman & Co LP | 99,340 | $2.14M | 0.12% | +31,062+45.5% | Added |
| Oberweis Asset Management Inc | 85,000 | $1.83M | 0.22% | +24,695+41.0% | Added |
| Norges Bank | 84,100 | $1.81M | 0.00% | −7,800−8.5% | Reduced |
| Barclays PLC | 77,984 | $1.68M | 0.00% | −3,922−4.8% | Reduced |
| Citigroup Inc | 77,569 | $1.67M | 0.00% | +44,443+134.2% | Added |
| Polar Asset Management Partners Inc. | 77,000 | $1.66M | 0.03% | −100,200−56.5% | Reduced |
| UBS Group AG | 74,075 | $1.60M | 0.00% | +27,522+59.1% | Added |
| Rhumbline Advisers | 68,095 | $1.47M | 0.00% | −7,867−10.4% | Reduced |
| Bank of Montreal | 59,230 | $1.42M | 0.00% | +59,230 | New |
| Swiss National Bank | 65,400 | $1.41M | 0.00% | +65,400 | New |
| Tudor Investment Corp Et Al | 59,615 | $1.29M | 0.02% | +22,051+58.7% | Added |
| Wells Fargo & Company | 57,495 | $1.24M | 0.00% | +35,545+161.9% | Added |
| Cornercap Investment Counsel Inc | 56,310 | $1.21M | 0.21% | +56,310 | New |
| Cubist Systematic Strategies, LLC | 54,248 | $1.17M | 0.01% | −9,750−15.2% | Reduced |
| First Trust Advisors LP | 54,115 | $1.17M | 0.00% | +26,798+98.1% | Added |
| Walleye Capital LLC | 52,378 | $1.13M | 0.02% | +52,378 | New |
| Alliancebernstein L.P. | 51,542 | $1.11M | 0.00% | 00.0% | Unchanged |
| Alps Advisors Inc | 49,380 | $1.07M | 0.01% | +5,724+13.1% | Added |
| HRT Financial LP | 49,206 | $1.06M | 0.01% | −44,584−47.5% | Reduced |
| Mariner, LLC | 48,642 | $1.05M | 0.00% | +37+0.1% | Added |
| Putnam Investments LLC | 46,862 | $1.01M | 0.00% | −1,459−3.0% | Reduced |
| Squarepoint Ops LLC | 45,810 | $988.1K | 0.01% | −45,916−50.1% | Reduced |
| California State Teachers Retirement System | 43,307 | $934.1K | 0.00% | +24,545+130.8% | Added |
| Simplex Trading, LLC | 43,055 | $928.0K | 0.04% | +43,055 | New |
| Dark Forest Capital Management LP | 40,048 | $863.8K | 0.09% | +35,285+740.8% | Added |
| UBS Oconnor LLC | 39,000 | $841.2K | 0.02% | +39,000 | New |
| Caption Management, LLC | 37,000 | $798.1K | 0.14% | +37,000 | New |
| Hennion & Walsh Asset Management, Inc. | 35,139 | $758.0K | 0.04% | +14,718+72.1% | Added |
| Captrust Financial Advisors | 33,513 | $722.9K | 0.00% | +33,513 | New |
| Credit Suisse AG | 33,317 | $718.6K | 0.00% | +33,317 | New |
| Aigen Investment Management, LP | 33,058 | $713.1K | 0.11% | +33,058 | New |
| DekaBank Deutsche Girozentrale | 33,000 | $692.0K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 32,073 | $691.8K | 0.00% | +32,073 | New |
| Graham Capital Management, L.P. | 30,552 | $659.0K | 0.02% | +30,552 | New |
| Legal & General Group Plc | 28,516 | $615.1K | 0.00% | +1,464+5.4% | Added |
| Franklin Resources Inc | 28,486 | $614.4K | 0.00% | +28,486 | New |
| Engineers Gate Manager LP | 27,382 | $590.6K | 0.02% | +4,260+18.4% | Added |
| Jackson Creek Investment Advisors LLC | 27,218 | $587.0K | 0.23% | +1,972+7.8% | Added |
| Invesco Ltd. | 26,740 | $576.8K | 0.00% | +3,803+16.6% | Added |
| MetLife Investment Management | 26,712 | $576.2K | 0.00% | 00.0% | Unchanged |
| International Biotechnology Trust PLC | 25,000 | $538.5K | 0.16% | +25,000 | New |