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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
170
+18 vs. Q2 2023
Shares held
58.9M
+5.09M (+9.5%) vs. Q2 2023
Total value
$1.08B
−$82.5M (−7.1%) vs. Q2 2023
New holders
34
68 more added
Sold out
16
48 more reduced

2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 170 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ3 2023: $1.08B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q2 2023.

Institutions holding AMLX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Nebula Research & Development LLC28,022$513.1K0.27%+28,022New
UBS Asset Management Americas Inc27,800$509.0K0.00%+27,800New
Tudor Investment Corp Et Al27,359$500.9K0.01%−32,256−54.1%Reduced
Jackson Creek Investment Advisors LLC27,193$498.0K0.21%−25−0.1%Reduced
Manufacturers Life Insurance Company, The27,130$496.8K0.00%+6,299+30.2%Added
MetLife Investment Management26,712$489.1K0.00%00.0%Unchanged
HighVista Strategies LLC26,349$482.4K0.22%+12,601+91.7%Added
Axxcess Wealth Management, LLC26,151$478.8K0.02%+26,151New
HRT Financial LP26,094$477.0K0.00%−23,112−47.0%Reduced
Barclays PLC25,699$470.5K0.00%−52,285−67.0%Reduced
State of Wisconsin Investment Board25,695$470.5K0.00%−6,378−19.9%Reduced
Advisor Group Holdings, Inc.25,664$469.9K0.00%+22,142+628.7%Added
American International Group, Inc.25,348$464.1K0.00%+901+3.7%Added
Knoll Capital Management, LLC24,772$453.6K0.47%+24,772New
Deutsche Bank AG24,416$447.1K0.00%−167,195−87.3%Reduced
Mirae Asset Global Investments Co., Ltd.24,254$444.1K0.00%+905+3.9%Added
Price T Rowe Associates Inc24,220$444.0K0.00%+1,132+4.9%Added
AQR Capital Management LLC23,639$432.8K0.00%+9,408+66.1%Added
Point72 Middle East FZE23,374$428.0K0.03%+850+3.8%Added
Jump Financial, LLC22,840$418.2K0.02%−118,607−83.9%Reduced
Capstone Investment Advisors, LLC22,829$418.0K0.01%+22,829New
Simplex Trading, LLC22,552$412.0K0.02%−20,503−47.6%Reduced
Parsons Capital Management Inc21,945$401.8K0.03%00.0%Unchanged
SG Americas Securities, LLC21,255$389.0K0.01%+12,936+155.5%Added
New York State Common Retirement Fund21,235$388.8K0.00%−2,100−9.0%Reduced
Millrace Asset Group, Inc.19,496$357.0K0.44%+19,496New
Profund Advisors LLC19,368$354.6K0.02%+5,558+40.2%Added
Greenwood Capital Associates LLC17,352$317.7K0.05%+17,352New
Fox Run Management, L.L.C.16,985$311.0K0.09%−1,007−5.6%Reduced
Prelude Capital Management, LLC16,600$303.9K0.03%+6,500+64.4%Added
Janus Henderson Group PLC14,754$270.1K0.00%+10.0%Added
State Board of Administration of Florida Retirement System14,580$267.0K0.00%+160+1.1%Added
Principal Financial Group Inc14,346$262.7K0.00%−332−2.3%Reduced
Engineers Gate Manager LP14,316$262.1K0.01%−13,066−47.7%Reduced
Allspring Global Investments Holdings, LLC14,187$259.8K0.00%−2,607−15.5%Reduced
Weiss Multi-Strategy Advisers LLC14,054$257.0K0.01%−1,657−10.5%Reduced
Brown Advisory Inc13,461$246.5K0.00%00.0%Unchanged
CWM, LLC13,169$241.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC12,223$223.8K0.14%−1,583−11.5%Reduced
Teza Capital Management LLC11,797$216.0K0.04%+11,797New
Rafferty Asset Management, LLC11,292$206.8K0.00%+11,292New
ProShare Advisors LLC11,006$201.5K0.00%+54+0.5%Added
Axq Capital, LP10,836$198.4K0.07%+10,836New
Integrated Wealth Concepts LLC10,356$189.6K0.00%00.0%Unchanged
XTX Topco Ltd10,099$184.9K0.03%+10,099New
Advisors Asset Management, Inc.8,643$158.3K0.00%+2,780+47.4%Added
Royal Bank of Canada8,095$148.0K0.00%+4,021+98.7%Added
Amalgamated Bank7,717$141.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)6,134$112.3K0.00%+859+16.3%Added
Ameritas Investment Partners, Inc.5,046$92.4K0.00%+1,011+25.1%Added
Quarry LP5,000$91.5K0.06%+5,000New
UBS Group AG4,611$84.4K0.00%−69,464−93.8%Reduced
Russell Investments Group, Ltd.4,483$82.1K0.00%+4,289+2,210.8%Added
Tower Research Capital LLC (TRC)3,971$72.7K0.00%−295−6.9%Reduced
Metropolitan Life Insurance Co2,899$53.1K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC2,200$40.3K0.00%+1,100+100.0%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP1,803$32.5K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.1,730$31.7K0.01%+850+96.6%Added
Credit Agricole S A500$9.15K0.00%+300+150.0%Added
Tradition Wealth Management, LLC500$9.00K0.00%00.0%Unchanged
Daiwa Securities Group Inc.266$5.00K0.00%00.0%Unchanged
Capital Advisors, Ltd. LLC290$5.00K0.00%00.0%Unchanged
Psagot Value Holdings Ltd. / (Israel)117$2.00K0.00%+117New
Allworth Financial LP100$1.83K0.00%+100New
Colonial Trust Co86$1.80K0.00%+86New
Point72 Asset Management, L.P.46$8420.00%−7,061−99.4%Reduced
Kelly Financial Services LLC33$6040.00%00.0%Unchanged
Nisa Investment Advisors, LLC16$2930.00%−2−11.1%Reduced
Covestor Ltd4$00.00%00.0%Unchanged
Cutler Group LP50$00.00%+50New
Deerfield Management Company, L.P. (Series C)0$00.00%−1,050,198−100.0%Sold out
Great Point Partners LLC0$00.00%−968,795−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−244,493−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−120,000−100.0%Sold out
Tang Capital Management LLC0$00.00%−100,000−100.0%Sold out
Norges Bank0$00.00%−84,100−100.0%Sold out
Bank of Montreal0$00.00%−59,230−100.0%Sold out
First Trust Advisors LP0$00.00%−54,115−100.0%Sold out
Virtu Financial LLC0$00.00%−17,742−100.0%Sold out
Wellington Management Group LLP0$00.00%−17,716−100.0%Sold out
Capital Fund Management S.A.0$00.00%−12,281−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−10,050−100.0%Sold out
Tucker Asset Management LLC0$00.00%−8,754−100.0%Sold out
PEAK6 Investments LLC0$00.00%−1,500−100.0%Sold out
Connective Capital Management, LLC0$00.00%−466−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−5−100.0%Sold out
Pictet Asset Management SA––––Not filed
Tekla Capital Management LLC––––Not filed