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Amylyx Pharmaceuticals, Inc.

AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001658551

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Amylyx Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
147
+14 vs. Q4 2022
Shares held
51.4M
+2.80M (+5.8%) vs. Q4 2022
Total value
$1.51B
−$286.0M (−15.9%) vs. Q4 2022
New holders
38
60 more added
Sold out
24
36 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AMLX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 147 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 95 institutionsQ4 2022: 133 institutionsQ1 2023: 147 institutionsQ2 2023: 154 institutionsQ3 2023: 170 institutionsQ4 2023: 178 institutionsQ1 2024: 143 institutionsQ2 2024: 119 institutionsQ3 2024: 110 institutionsQ4 2024: 122 institutionsQ1 2025: 136 institutionsQ2 2025: 131 institutionsQ3 2025: 169 institutionsQ4 2025: 180 institutionsQ1 2026: 171 institutionsQ2 2026: 206 institutions
Value heldQ1 2023: $1.51B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $299.9MQ2 2022: $512.9MQ3 2022: $1.05BQ4 2022: $1.79BQ1 2023: $1.51BQ2 2023: $1.18BQ3 2023: $1.08BQ4 2023: $887.4MQ1 2024: $141.5MQ2 2024: $82.9MQ3 2024: $140.8MQ4 2024: $188.3MQ1 2025: $261.6MQ2 2025: $523.6MQ3 2025: $1.49BQ4 2025: $1.36BQ1 2026: $1.59BQ2 2026: $2.07B
Institutions holding AMLX and their total value by quarter
QuarterHoldersValue
Q2 2026206$2.07B
Q1 2026171$1.59B
Q4 2025180$1.36B
Q3 2025169$1.49B
Q2 2025131$523.6M
Q1 2025136$261.6M
Q4 2024122$188.3M
Q3 2024110$140.8M
Q2 2024119$82.9M
Q1 2024143$141.5M
Q4 2023178$887.4M
Q3 2023170$1.08B
Q2 2023154$1.18B
Q1 2023147$1.51B
Q4 2022133$1.79B
Q3 202295$1.05B
Q2 202278$512.9M
Q1 202272$299.9M
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Amylyx Pharmaceuticals, Inc.; share changes are against Q4 2022.

Institutions holding AMLX in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd4$00.00%00.0%Unchanged
Quadrant Capital Group LLC12$3530.00%+12New
US Bancorp18$5280.00%−6,977−99.7%Reduced
Ellevest, Inc.32$9390.00%+32New
Russell Investments Group, Ltd.32$9390.00%+32New
Kelly Financial Services LLC33$9680.00%00.0%Unchanged
Nisa Investment Advisors, LLC26$1.00K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.100$2.93K0.00%+100New
TCI Wealth Advisors, Inc.142$4.17K0.00%+142New
Credit Agricole S A200$5.87K0.00%00.0%Unchanged
Daiwa Securities Group Inc.266$8.00K0.00%00.0%Unchanged
Connective Capital Management, LLC466$13.7K0.02%00.0%Unchanged
Advisory Services Network, LLC500$14.7K0.00%00.0%Unchanged
Tradition Wealth Management, LLC500$15.0K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)687$20.2K0.00%+687New
China Universal Asset Management Co., Ltd.897$26.3K0.01%+224+33.3%Added
Steward Partners Investment Advisory, LLC1,000$29.3K0.00%−100−9.1%Reduced
Advisor Group Holdings, Inc.1,322$38.8K0.00%−53−3.9%Reduced
Values First Advisors, Inc.1,733$50.9K0.03%+1,733New
Tower Research Capital LLC (TRC)1,812$54.0K0.00%−86−4.5%Reduced
CWM, LLC2,657$78.0K0.00%+2,657New
Metropolitan Life Insurance Co2,899$85.1K0.00%−251−8.0%Reduced
Group One Trading, L.P.3,602$105.7K0.01%−21,936−85.9%Reduced
Tucker Asset Management LLC3,625$106.4K0.03%+3,625New
Royal Bank of Canada3,628$107.0K0.00%−3,049−45.7%Reduced
Ameritas Investment Partners, Inc.4,035$118.4K0.00%00.0%Unchanged
Advisors Asset Management, Inc.4,645$136.3K0.00%+740+19.0%Added
Dark Forest Capital Management LP4,763$139.7K0.03%+4,753+47,530.0%Added
Quantbot Technologies LP4,859$142.6K0.01%+4,859New
Amalgamated Bank5,663$166.0K0.00%−1,362−19.4%Reduced
FMR LLC7,230$212.1K0.00%−574−7.4%Reduced
Prelude Capital Management, LLC7,300$214.2K0.01%+7,300New
AlphaCentric Advisors LLC7,500$220.1K0.15%+7,500New
AQR Capital Management LLC7,847$230.2K0.00%+7,847New
Gsa Capital Partners LLP8,109$238.0K0.02%+8,109New
State Board of Administration of Florida Retirement System8,310$243.8K0.00%00.0%Unchanged
Artia Global Partners LP8,339$244.7K0.10%−15,544−65.1%Reduced
Virtus ETF Advisers LLC8,460$248.2K0.14%+153+1.8%Added
SG Americas Securities, LLC9,188$270.0K0.00%−1,301−12.4%Reduced
Boulder Hill Capital Management LP9,400$275.8K0.22%+9,400New
Ikarian Capital, LLC10,000$293.4K0.12%+10,000New
Capstone Investment Advisors, LLC10,150$297.8K0.01%+10,150New
Integrated Wealth Concepts LLC10,368$304.0K0.01%−2,000−16.2%Reduced
ProShare Advisors LLC10,528$308.9K0.00%−1,440−12.0%Reduced
Axq Capital, LP10,600$311.0K0.12%+10,600New
STRS Ohio12,300$360.0K0.00%+7,800+173.3%Added
Fox Run Management, L.L.C.12,498$366.7K0.12%+12,498New
Kula Investments, LLC12,507$367.0K0.09%+12,507New
Profund Advisors LLC12,939$379.6K0.02%+12,939New
XTX Topco Ltd14,751$432.8K0.09%+14,751New
Principal Financial Group Inc14,997$440.0K0.00%+1,484+11.0%Added
Bayesian Capital Management, LP16,350$479.7K0.06%+1,650+11.2%Added
Virtu Financial LLC18,261$536.0K0.06%+18,261New
Brown Advisory Inc18,461$541.6K0.00%−14,980−44.8%Reduced
California State Teachers Retirement System18,762$550.5K0.00%−1,369−6.8%Reduced
Manufacturers Life Insurance Company, The20,219$593.2K0.00%+83+0.4%Added
Hennion & Walsh Asset Management, Inc.20,421$599.0K0.04%+3,465+20.4%Added
Parsons Capital Management Inc21,945$643.9K0.05%−5,200−19.2%Reduced
Wells Fargo & Company21,950$644.0K0.00%+20,231+1,176.9%Added
Price T Rowe Associates Inc22,507$661.0K0.00%+6,824+43.5%Added
Invesco Ltd.22,937$673.0K0.00%−192,533−89.4%Reduced
Engineers Gate Manager LP23,122$678.4K0.03%+23,122New
Mirae Asset Global Investments Co., Ltd.23,464$688.4K0.00%−43−0.2%Reduced
American International Group, Inc.24,338$714.1K0.00%+485+2.0%Added
Jackson Creek Investment Advisors LLC25,246$741.0K0.31%+25,246New
MetLife Investment Management26,712$783.7K0.01%00.0%Unchanged
New York State Common Retirement Fund26,731$784.3K0.00%−6,972−20.7%Reduced
Legal & General Group Plc27,052$793.7K0.00%+22,029+438.6%Added
First Trust Advisors LP27,317$801.5K0.00%−29,503−51.9%Reduced
Pentwater Capital Management LP30,000$880.2K0.01%−5,000−14.3%Reduced
Seven Eight Capital, LP30,053$881.8K0.18%+15,115+101.2%Added
Susquehanna International Group, LLP30,610$898.1K0.00%+30,610New
Dynamic Technology Lab Private Ltd30,857$906.0K0.08%+30,857New
DekaBank Deutsche Girozentrale33,000$914.0K0.00%+33,000New
Deutsche Bank AG31,320$918.9K0.00%+9,359+42.6%Added
Qube Research & Technologies Ltd31,725$930.8K0.01%+31,725New
Citigroup Inc33,126$971.9K0.00%+23,403+240.7%Added
Tudor Investment Corp Et Al37,564$1.10M0.02%+1,567+4.4%Added
Alps Advisors Inc43,656$1.28M0.01%−1,256−2.8%Reduced
UBS Group AG46,553$1.37M0.00%+43,076+1,238.9%Added
Putnam Investments LLC48,321$1.42M0.00%+25,289+109.8%Added
Mariner, LLC48,605$1.43M0.00%+10,614+27.9%Added
Alliancebernstein L.P.51,542$1.51M0.00%+15,300+42.2%Added
Weiss Multi-Strategy Advisers LLC54,054$1.59M0.04%+54,054New
Oberweis Asset Management Inc60,305$1.77M0.27%+60,305New
Soleus Capital Management, L.P.63,214$1.85M0.23%+12,578+24.8%Added
Cubist Systematic Strategies, LLC63,998$1.88M0.02%+60,192+1,581.5%Added
J. Goldman & Co LP68,278$2.00M0.12%+22,636+49.6%Added
Bank of America Corp68,324$2.00M0.00%+4,958+7.8%Added
SEI Investments Co69,665$2.04M0.00%+55,888+405.7%Added
Rhumbline Advisers75,962$2.23M0.00%+4,398+6.1%Added
Barclays PLC81,906$2.40M0.00%+43,411+112.8%Added
Squarepoint Ops LLC91,726$2.69M0.02%+51,726+129.3%Added
Norges Bank91,900$2.70M0.00%+10,700+13.2%Added
HRT Financial LP93,790$2.75M0.03%+93,790New
Maven Securities LTD100,000$2.93M0.46%−50,000−33.3%Reduced
Tang Capital Management LLC100,000$2.93M0.44%00.0%Unchanged
JPMorgan Chase & Co101,700$2.98M0.00%+51,999+104.6%Added
Wellington Management Group LLP108,429$3.18M0.00%+40,524+59.7%Added
Twinbeech Capital LP131,772$3.87M0.08%+131,772New