Amylyx Pharmaceuticals, Inc.

AMLX

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001658551

SEC filings (opens in a new tab)

In the last 90 days, Amylyx Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 206 institutions reported holding it in 13F filings for Q2 2026, worth $2.07B in total; no superinvestor holds it.

Q1 2025 vs. Q4 2024

How the institutions holding Amylyx Pharmaceuticals, Inc. changed between Q4 2024 and Q1 2025.

All holders in Q1 2025 All holders in Q4 2024

13F holders of AMLX: Q4 2024 compared with Q1 2025
Measure	Q4 2024	Of which not filed for Q1 2025	Q1 2025	Change
Holders	122	2	136	+16
Shares	49.8M	1.50K	73.9M	+24.1M (+48.4%)
Value	$188.3M	$5.67K	$261.6M	+$73.3M (+39.0%)

2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (32)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q1 2025 but not at the end of Q4 2024.

Institutions new to AMLX in Q1 2025
Institution	Shares	Value	% of portfolio
Adage Capital Partners GP, L.L.C.	5,697,605	$20.2M	0.04%
Great Point Partners LLC	1,811,996	$6.41M	3.49%
Woodline Partners LP	1,609,447	$5.70M	0.04%
ADAR1 Capital Management, LLC	1,471,587	$5.21M	1.00%
Point72 Asset Management, L.P.	916,966	$3.25M	0.01%
PFM Health Sciences, LP	834,135	$2.95M	0.23%
Rock Springs Capital Management LP	343,228	$1.22M	0.07%
Allostery Investments LP	266,099	$942.0K	1.36%
HRT Financial LP	127,998	$453.0K	0.00%
Cantor Fitzgerald, L. P.	100,000	$354.0K	0.01%
Jain Global LLC	73,942	$261.8K	0.01%
Algert Global LLC	57,133	$202.3K	0.01%
Invesco Ltd.	45,694	$161.8K	0.00%
LMR Partners LLP	43,228	$153.0K	0.00%
Quantessence Capital LLC	40,134	$142.1K	0.04%
Cannon Global Investment Management, LLC	25,500	$90.3K	0.25%
Verition Fund Management LLC	24,013	$85.0K	0.00%
Paloma Partners Management Co	22,242	$78.7K	0.01%
Premier Path Wealth Partners, LLC	20,265	$71.7K	0.01%
Capstone Investment Advisors, LLC	16,150	$57.2K	0.00%
Catalyst Funds Management Pty Ltd	14,905	$52.8K	0.01%
Two Sigma Securities, LLC	13,301	$47.1K	0.01%
Quadrature Capital Ltd	12,744	$45.0K	0.00%
Brevan Howard Capital Management LP	11,330	$40.1K	0.00%
Capula Management Ltd	10,980	$38.9K	0.00%
Hudson Bay Capital Management LP	10,340	$36.6K	0.00%
Valeo Financial Advisors, LLC	10,000	$35.4K	0.00%
Zurcher Kantonalbank (Zurich Cantonalbank)	3,152	$11.2K	0.00%
Caitong International Asset Management Co., Ltd	2,229	$7.89K	0.01%
North Capital, Inc.	500	$1.77K	0.00%
UMA Financial Services, Inc.	274	$970	0.00%
Coldstream Capital Management Inc	238	$843	0.00%

Sold out (16)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.

Institutions that sold out of AMLX in Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Ikarian Capital, LLC	201,187	$760.5K
AQR Capital Management LLC	188,386	$712.1K
Mackenzie Financial Corp	111,310	$420.8K
Jump Financial, LLC	104,342	$394.4K
Boothbay Fund Management, LLC	80,543	$304.5K
Landscape Capital Management, L.L.C.	49,661	$187.7K
Wedbush Securities Inc	19,914	$75.0K
Y-Intercept (Hong Kong) Ltd	14,809	$56.0K
Rpo LLC	12,136	$45.9K
Alpine Global Management, LLC	12,017	$45.4K
Bank of Nova Scotia	11,884	$44.9K
Fox Run Management, L.L.C.	11,788	$44.6K
Vident Advisory, LLC	10,862	$41.1K
Walleye Trading LLC	2,649	$10.0K
SRS Capital Advisors, Inc.	2,193	$8.29K
Advisor Group Holdings, Inc.	638	$2.41K

Not filed for Q1 2025 yet (2)

Institutions that held Amylyx Pharmaceuticals, Inc. at the end of Q4 2024 and haven't filed a 13F for Q1 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding AMLX in Q4 2024 that haven't filed for Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Oliver Lagore Vanvalin Investment Group	1,100	$4.16K
Global Retirement Partners, LLC	400	$1.51K