Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 164
- +32 vs. Q4 2025
- Shares held
- 65.9M
- +10.7M (+19.3%) vs. Q4 2025
- Total value
- $2.52B
- +$1.07B (+73.8%) vs. Q4 2025
- New holders
- 46
- 59 more added
- Sold out
- 14
- 35 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Canada Pension Plan Investment Board | 14,300 | $547.7K | 0.00% | −14,600−50.5% | Reduced |
| ExodusPoint Capital Management, LP | 14,066 | $538.7K | 0.01% | −28,725−67.1% | Reduced |
| MetLife Investment Management | 13,993 | $535.9K | 0.00% | −1,363−8.9% | Reduced |
| Franklin Resources Inc | 12,970 | $496.8K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 12,049 | $461.5K | 0.13% | +293+2.5% | Added |
| Wells Fargo & Company | 11,672 | $447.0K | 0.00% | −17,377−59.8% | Reduced |
| Baker Bros. Advisors LP | 10,607 | $406.2K | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 10,169 | $389.5K | 0.00% | +10,169 | New |
| Soleus Capital Management, L.P. | 10,000 | $383.0K | 0.02% | −115,000−92.0% | Reduced |
| Legal & General Group Plc | 9,537 | $364.8K | 0.00% | +7,170+302.9% | Added |
| China Universal Asset Management Co., Ltd. | 9,471 | $362.7K | 0.03% | +774+8.9% | Added |
| Vanguard Asset Management, Ltd | 8,991 | $344.4K | 0.00% | +8,991 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 8,075 | $309.3K | 0.45% | +8,075 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,038 | $307.9K | 0.00% | +8,038 | New |
| Bridgefront Capital, LLC | 7,911 | $303.0K | 0.08% | +7,911 | New |
| UBS Asset Management Americas Inc | 7,832 | $300.0K | 0.00% | +7,832 | New |
| New York State Common Retirement Fund | 7,423 | $284.3K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 7,215 | $276.0K | 0.00% | +7,215 | New |
| Allianz Asset Management GmbH | 7,000 | $268.1K | 0.00% | +7,000 | New |
| Police & Firemen's Retirement System of New Jersey | 6,440 | $246.7K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 6,345 | $243.0K | 0.00% | −3,456−35.3% | Reduced |
| ProShare Advisors LLC | 6,142 | $235.2K | 0.00% | +6,142 | New |
| Citigroup Inc | 5,991 | $229.5K | 0.00% | +2,174+57.0% | Added |
| Graham Capital Management, L.P. | 5,756 | $220.5K | 0.01% | +5,756 | New |
| Persistent Asset Partners Ltd | 4,518 | $173.0K | 0.07% | +4,518 | New |
| Tower Research Capital LLC (TRC) | 3,005 | $115.1K | 0.00% | +2,674+807.9% | Added |
| Vanguard Investments Australia, Ltd. | 2,928 | $112.1K | 0.00% | +2,928 | New |
| KLP Kapitalforvaltning AS | 2,900 | $111.1K | 0.00% | +2,900 | New |
| Mirae Asset Global Investments Co., Ltd. | 2,784 | $106.6K | 0.00% | +190+7.3% | Added |
| Chung Wu Investment Group, LLC | 2,000 | $76.6K | 0.07% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 1,991 | $76.3K | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 1,891 | $72.4K | 0.01% | −1,106−36.9% | Reduced |
| Steward Partners Investment Advisory, LLC | 1,577 | $60.4K | 0.00% | +1,500+1,948.1% | Added |
| CWM, LLC | 1,566 | $60.0K | 0.00% | +20+1.3% | Added |
| California State Teachers Retirement System | 1,402 | $53.7K | 0.00% | −193−12.1% | Reduced |
| GF Fund Management Co. Ltd. | 1,198 | $45.9K | 0.00% | +150+14.3% | Added |
| Sterling Capital Management LLC | 858 | $32.9K | 0.00% | −630−42.3% | Reduced |
| Versant Capital Management, Inc | 819 | $31.4K | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 772 | $29.6K | 0.02% | +772 | New |
| Federated Hermes, Inc. | 714 | $27.3K | 0.00% | −583−44.9% | Reduced |
| Advisor Group Holdings, Inc. | 551 | $21.1K | 0.00% | −637−53.6% | Reduced |
| GAMMA Investing LLC | 506 | $19.4K | 0.00% | +34+7.2% | Added |
| Rockefeller Capital Management L.P. | 421 | $16.1K | 0.00% | +337+401.2% | Added |
| Larson Financial Group LLC | 295 | $11.3K | 0.00% | +149+102.1% | Added |
| Quantbot Technologies LP | 243 | $9.31K | 0.00% | +243 | New |
| The PNC Financial Services Group, Inc. | 223 | $8.54K | 0.00% | +15+7.2% | Added |
| True Wealth Design, LLC | 142 | $5.44K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 128 | $4.90K | 0.00% | +86+204.8% | Added |
| Smartleaf Asset Management LLC | 127 | $4.39K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 106 | $4.06K | 0.00% | −22−17.2% | Reduced |
| Allworth Financial LP | 104 | $3.98K | 0.00% | +4+4.0% | Added |
| Atlantic Union Bankshares Corp | 100 | $3.83K | 0.00% | +100 | New |
| Nisa Investment Advisors, LLC | 88 | $3.37K | 0.00% | +2+2.3% | Added |
| Royal Bank of Canada | 88 | $3.00K | 0.00% | −654−88.1% | Reduced |
| Rothschild Investment LLC | 70 | $2.68K | 0.00% | +15+27.3% | Added |
| Farther Finance Advisors, LLC | 60 | $2.30K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 43 | $1.65K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 29 | $1.10K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 11 | $421 | 0.00% | +11 | New |
| Twin Peaks Wealth Advisors, LLC | 7 | $268 | 0.00% | +7 | New |
| MAI Capital Management | 4 | $154 | 0.00% | +4 | New |
| SBI Securities Co., Ltd. | 4 | $153 | 0.00% | 00.0% | Unchanged |
| TFC Financial Management | 1 | $39 | 0.00% | +1 | New |
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| Kynam Capital Management, LP | 0 | $0 | 0.00% | −1,564,492−100.0% | Sold out |
| Trails Edge Capital Partners, LP | 0 | $0 | 0.00% | −700,000−100.0% | Sold out |
| Boone Capital Management LLC | 0 | $0 | 0.00% | −398,482−100.0% | Sold out |
| Investment Counsel Co of Nevada | 0 | $0 | 0.00% | −85,020−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −58,900−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −58,677−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −45,942−100.0% | Sold out |
| Bank of Nova Scotia | 0 | $0 | 0.00% | −11,100−100.0% | Sold out |
| VARCOV Co. | 0 | $0 | 0.00% | −9,708−100.0% | Sold out |
| Bellevue Group AG | 0 | $0 | 0.00% | −3,143−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −2,139−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −814−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −173−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −3−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |