Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 164
- +32 vs. Q4 2025
- Shares held
- 65.9M
- +10.7M (+19.3%) vs. Q4 2025
- Total value
- $2.52B
- +$1.07B (+73.8%) vs. Q4 2025
- New holders
- 46
- 59 more added
- Sold out
- 14
- 35 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| TFC Financial Management | 1 | $39 | 0.00% | +1 | New |
| SBI Securities Co., Ltd. | 4 | $153 | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 4 | $154 | 0.00% | +4 | New |
| Twin Peaks Wealth Advisors, LLC | 7 | $268 | 0.00% | +7 | New |
| US Bancorp | 11 | $421 | 0.00% | +11 | New |
| Clearstead Advisors, LLC | 29 | $1.10K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 43 | $1.65K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 60 | $2.30K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 70 | $2.68K | 0.00% | +15+27.3% | Added |
| Royal Bank of Canada | 88 | $3.00K | 0.00% | −654−88.1% | Reduced |
| Nisa Investment Advisors, LLC | 88 | $3.37K | 0.00% | +2+2.3% | Added |
| Atlantic Union Bankshares Corp | 100 | $3.83K | 0.00% | +100 | New |
| Allworth Financial LP | 104 | $3.98K | 0.00% | +4+4.0% | Added |
| Optiver Holding B.V. | 106 | $4.06K | 0.00% | −22−17.2% | Reduced |
| Smartleaf Asset Management LLC | 127 | $4.39K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 128 | $4.90K | 0.00% | +86+204.8% | Added |
| True Wealth Design, LLC | 142 | $5.44K | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 223 | $8.54K | 0.00% | +15+7.2% | Added |
| Quantbot Technologies LP | 243 | $9.31K | 0.00% | +243 | New |
| Larson Financial Group LLC | 295 | $11.3K | 0.00% | +149+102.1% | Added |
| Rockefeller Capital Management L.P. | 421 | $16.1K | 0.00% | +337+401.2% | Added |
| GAMMA Investing LLC | 506 | $19.4K | 0.00% | +34+7.2% | Added |
| Advisor Group Holdings, Inc. | 551 | $21.1K | 0.00% | −637−53.6% | Reduced |
| Federated Hermes, Inc. | 714 | $27.3K | 0.00% | −583−44.9% | Reduced |
| Hilton Head Capital Partners, LLC | 772 | $29.6K | 0.02% | +772 | New |
| Versant Capital Management, Inc | 819 | $31.4K | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 858 | $32.9K | 0.00% | −630−42.3% | Reduced |
| GF Fund Management Co. Ltd. | 1,198 | $45.9K | 0.00% | +150+14.3% | Added |
| California State Teachers Retirement System | 1,402 | $53.7K | 0.00% | −193−12.1% | Reduced |
| CWM, LLC | 1,566 | $60.0K | 0.00% | +20+1.3% | Added |
| Steward Partners Investment Advisory, LLC | 1,577 | $60.4K | 0.00% | +1,500+1,948.1% | Added |
| Caitong International Asset Management Co., Ltd | 1,891 | $72.4K | 0.01% | −1,106−36.9% | Reduced |
| Ameritas Investment Partners, Inc. | 1,991 | $76.3K | 0.00% | 00.0% | Unchanged |
| Chung Wu Investment Group, LLC | 2,000 | $76.6K | 0.07% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,784 | $106.6K | 0.00% | +190+7.3% | Added |
| KLP Kapitalforvaltning AS | 2,900 | $111.1K | 0.00% | +2,900 | New |
| Vanguard Investments Australia, Ltd. | 2,928 | $112.1K | 0.00% | +2,928 | New |
| Tower Research Capital LLC (TRC) | 3,005 | $115.1K | 0.00% | +2,674+807.9% | Added |
| Persistent Asset Partners Ltd | 4,518 | $173.0K | 0.07% | +4,518 | New |
| Graham Capital Management, L.P. | 5,756 | $220.5K | 0.01% | +5,756 | New |
| Citigroup Inc | 5,991 | $229.5K | 0.00% | +2,174+57.0% | Added |
| ProShare Advisors LLC | 6,142 | $235.2K | 0.00% | +6,142 | New |
| Intech Investment Management LLC | 6,345 | $243.0K | 0.00% | −3,456−35.3% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 6,440 | $246.7K | 0.00% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 7,000 | $268.1K | 0.00% | +7,000 | New |
| SG Americas Securities, LLC | 7,215 | $276.0K | 0.00% | +7,215 | New |
| New York State Common Retirement Fund | 7,423 | $284.3K | 0.00% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 7,832 | $300.0K | 0.00% | +7,832 | New |
| Bridgefront Capital, LLC | 7,911 | $303.0K | 0.08% | +7,911 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,038 | $307.9K | 0.00% | +8,038 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 8,075 | $309.3K | 0.45% | +8,075 | New |
| Vanguard Asset Management, Ltd | 8,991 | $344.4K | 0.00% | +8,991 | New |
| China Universal Asset Management Co., Ltd. | 9,471 | $362.7K | 0.03% | +774+8.9% | Added |
| Legal & General Group Plc | 9,537 | $364.8K | 0.00% | +7,170+302.9% | Added |
| Soleus Capital Management, L.P. | 10,000 | $383.0K | 0.02% | −115,000−92.0% | Reduced |
| Jane Street Group, LLC | 10,169 | $389.5K | 0.00% | +10,169 | New |
| Baker Bros. Advisors LP | 10,607 | $406.2K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 11,672 | $447.0K | 0.00% | −17,377−59.8% | Reduced |
| Virtus Investment Advisers, Inc. | 12,049 | $461.5K | 0.13% | +293+2.5% | Added |
| Franklin Resources Inc | 12,970 | $496.8K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 13,993 | $535.9K | 0.00% | −1,363−8.9% | Reduced |
| ExodusPoint Capital Management, LP | 14,066 | $538.7K | 0.01% | −28,725−67.1% | Reduced |
| Canada Pension Plan Investment Board | 14,300 | $547.7K | 0.00% | −14,600−50.5% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 14,626 | $551.0K | 0.00% | +1,718+13.3% | Added |
| Victory Capital Management Inc | 15,230 | $583.3K | 0.00% | −3,560−18.9% | Reduced |
| Citadel Advisors LLC | 15,396 | $589.7K | 0.00% | +15,396 | New |
| Vanguard Global Advisers, LLC | 15,480 | $592.9K | 0.00% | +15,480 | New |
| Susquehanna International Group, LLP | 15,543 | $595.3K | 0.00% | −39,592−71.8% | Reduced |
| Profund Advisors LLC | 15,656 | $599.6K | 0.02% | +15,656 | New |
| PSP Research LLC | 16,000 | $612.8K | 0.43% | −5,853−26.8% | Reduced |
| Tudor Investment Corp Et Al | 16,284 | $623.7K | 0.00% | +16,284 | New |
| STRS Ohio | 18,100 | $693.2K | 0.00% | +17,400+2,485.7% | Added |
| Quadrature Capital Ltd | 18,203 | $697.2K | 0.01% | +18,203 | New |
| Walleye Capital LLC | 18,715 | $716.8K | 0.00% | +18,715 | New |
| Squarepoint Ops LLC | 20,494 | $784.9K | 0.00% | −33,930−62.3% | Reduced |
| Deutsche Bank AG | 20,495 | $785.0K | 0.00% | +4,118+25.1% | Added |
| Public Employees Retirement System of Ohio | 20,522 | $786.0K | 0.00% | +1,980+10.7% | Added |
| Auour Investments LLC | 21,020 | $805.1K | 0.25% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 31,990 | $841.0K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 23,948 | $917.2K | 0.00% | +4,345+22.2% | Added |
| Swiss National Bank | 26,400 | $1.01M | 0.00% | +26,400 | New |
| Eversept Partners, LP | 27,055 | $1.04M | 0.07% | −251,509−90.3% | Reduced |
| Fisher Asset Management, LLC | 28,800 | $1.10M | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 29,423 | $1.13M | 0.00% | +792+2.8% | Added |
| State of Wisconsin Investment Board | 33,258 | $1.27M | 0.00% | −5,765−14.8% | Reduced |
| Rafferty Asset Management, LLC | 34,856 | $1.33M | 0.01% | +19,401+125.5% | Added |
| Brevan Howard Capital Management LP | 38,606 | $1.46M | 0.02% | +38,606 | New |
| Voya Investment Management LLC | 38,358 | $1.47M | 0.00% | +8,471+28.3% | Added |
| Point72 Asset Management, L.P. | 38,850 | $1.49M | 0.00% | −835,342−95.6% | Reduced |
| Rhumbline Advisers | 39,660 | $1.52M | 0.00% | +870+2.2% | Added |
| Manufacturers Life Insurance Company, The | 40,224 | $1.54M | 0.00% | +31,867+381.3% | Added |
| Jump Financial, LLC | 41,375 | $1.58M | 0.02% | +41,375 | New |
| PDT Partners, LLC | 42,284 | $1.62M | 0.10% | 00.0% | Unchanged |
| Alps Advisors Inc | 43,856 | $1.68M | 0.01% | +29+0.1% | Added |
| Susquehanna Portfolio Strategies, LLC | 47,025 | $1.80M | 0.03% | −1,619−3.3% | Reduced |
| Arkadios Wealth Advisors | 47,567 | $1.82M | 0.03% | +47,567 | New |
| American Century Companies Inc | 47,929 | $1.84M | 0.00% | +1,702+3.7% | Added |
| TD Asset Management Inc | 50,000 | $1.92M | 0.00% | +50,000 | New |
| Nuveen, LLC | 50,840 | $1.95M | 0.00% | +3,491+7.4% | Added |