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Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Tyra Biosciences, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of TYRA: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders1331164+32
Shares56.8M1.57M65.9M+10.7M (+19.3%)
Value$1.49B$41.3M$2.52B+$1.07B (+73.8%)

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (46)

Institutions that held Tyra Biosciences, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to TYRA in Q1 2026
InstitutionSharesValue% of portfolio
Paradigm Biocapital Advisors LP2,054,991$78.7M1.61%
Vanguard Capital Management LLC1,125,970$43.1M0.00%
Jennison Associates LLC632,432$24.2M0.02%
Deerfield Management Company, L.P. (Series C)549,000$21.0M0.25%
Woodline Partners LP301,040$11.5M0.04%
Affinity Asset Advisors, LLC257,512$9.86M0.58%
Vanguard Portfolio Management LLC247,270$9.47M0.00%
Sofinnova Investments, Inc.204,015$7.81M0.39%
StemPoint Capital LP193,177$7.40M1.42%
Vanguard Fiduciary Trust Co157,791$6.04M0.00%
Trexquant Investment LP147,317$5.64M0.04%
Schonfeld Strategic Advisors LLC79,592$3.05M0.02%
Cinctive Capital Management LP78,018$2.99M0.20%
Ensign Peak Advisors, Inc74,064$2.84M0.01%
Catalio Capital Management, LP67,285$2.58M0.54%
TD Asset Management Inc50,000$1.92M0.00%
Arkadios Wealth Advisors47,567$1.82M0.03%
Jump Financial, LLC41,375$1.58M0.02%
Brevan Howard Capital Management LP38,606$1.46M0.02%
Swiss National Bank26,400$1.01M0.00%
Walleye Capital LLC18,715$716.8K0.00%
Quadrature Capital Ltd18,203$697.2K0.01%
Tudor Investment Corp Et Al16,284$623.7K0.00%
Profund Advisors LLC15,656$599.6K0.02%
Vanguard Global Advisers, LLC15,480$592.9K0.00%
Citadel Advisors LLC15,396$589.7K0.00%
Jane Street Group, LLC10,169$389.5K0.00%
Vanguard Asset Management, Ltd8,991$344.4K0.00%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.8,075$309.3K0.45%
Zurcher Kantonalbank (Zurich Cantonalbank)8,038$307.9K0.00%
Bridgefront Capital, LLC7,911$303.0K0.08%
UBS Asset Management Americas Inc7,832$300.0K0.00%
SG Americas Securities, LLC7,215$276.0K0.00%
Allianz Asset Management GmbH7,000$268.1K0.00%
ProShare Advisors LLC6,142$235.2K0.00%
Graham Capital Management, L.P.5,756$220.5K0.01%
Persistent Asset Partners Ltd4,518$173.0K0.07%
Vanguard Investments Australia, Ltd.2,928$112.1K0.00%
KLP Kapitalforvaltning AS2,900$111.1K0.00%
Hilton Head Capital Partners, LLC772$29.6K0.02%
Quantbot Technologies LP243$9.31K0.00%
Atlantic Union Bankshares Corp100$3.83K0.00%
US Bancorp11$4210.00%
Twin Peaks Wealth Advisors, LLC7$2680.00%
MAI Capital Management4$1540.00%
TFC Financial Management1$390.00%

Sold out (14)

Institutions that held Tyra Biosciences, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Institutions that sold out of TYRA in Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Kynam Capital Management, LP1,564,492$41.1M
Trails Edge Capital Partners, LP700,000$18.4M
Boone Capital Management LLC398,482$10.5M
Investment Counsel Co of Nevada85,020$2.24M
Two Sigma Advisers, LP58,900$1.55M
Superstring Capital Management LP58,677$1.54M
Y-Intercept (Hong Kong) Ltd45,942$1.21M
Bank of Nova Scotia11,100$291.8K
VARCOV Co.9,708$255.2K
Bellevue Group AG3,143$82.6K
Quest Partners LLC2,139$56.2K
Amalgamated Bank814$21.0K
Daiwa Securities Group Inc.173$5.00K
SRS Capital Advisors, Inc.3$79

Not filed for Q1 2026 yet (1)

Institutions that held Tyra Biosciences, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding TYRA in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc1,572,785$41.3M