Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 117
- +6 vs. Q4 2024
- Shares held
- 53.6M
- +9.07M (+20.4%) vs. Q4 2024
- Total value
- $499.5M
- −$119.2M (−19.3%) vs. Q4 2024
- New holders
- 22
- 42 more added
- Sold out
- 16
- 31 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Amalgamated Bank | 701 | $7.00K | 0.00% | +277+65.3% | Added |
| STRS Ohio | 700 | $6.51K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 677 | $6.00K | 0.00% | −97−12.5% | Reduced |
| Caitong International Asset Management Co., Ltd | 503 | $4.68K | 0.00% | +503 | New |
| Federated Hermes, Inc. | 475 | $4.42K | 0.00% | −553−53.8% | Reduced |
| CWM, LLC | 383 | $4.00K | 0.00% | +312+439.4% | Added |
| Daiwa Securities Group Inc. | 173 | $2.00K | 0.00% | +173 | New |
| Nisa Investment Advisors, LLC | 149 | $1.39K | 0.00% | +126+547.8% | Added |
| Allworth Financial LP | 100 | $1.01K | 0.00% | +100 | New |
| The PNC Financial Services Group, Inc. | 58 | $539 | 0.00% | 00.0% | Unchanged |
| Coldstream Capital Management Inc | 28 | $260 | 0.00% | +28 | New |
| Sterling Capital Management LLC | 21 | $195 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 16 | $149 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 9 | $84 | 0.00% | +9 | New |
| Rothschild Investment LLC | 5 | $47 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 4 | $37 | 0.00% | −15−78.9% | Reduced |
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| Boxer Capital Management, LLC | 0 | $0 | 0.00% | −2,027,678−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −39,093−100.0% | Sold out |
| PDT Partners, LLC | 0 | $0 | 0.00% | −20,359−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −18,216−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −17,560−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −13,368−100.0% | Sold out |
| Franklin Resources Inc | 0 | $0 | 0.00% | −12,751−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −4,686−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −1,480−100.0% | Sold out |
| Aster Capital Management (DIFC) Ltd | 0 | $0 | 0.00% | −214−100.0% | Sold out |
| Creative Planning | 0 | $0 | 0.00% | −63−100.0% | Sold out |
| GAMMA Investing LLC | 0 | $0 | 0.00% | −26−100.0% | Sold out |
| Signaturefd, LLC | 0 | $0 | 0.00% | −24−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Nextech Invest AG | – | – | – | – | Not filed |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |