Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Tyra Biosciences, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 117
- +6 vs. Q4 2024
- Shares held
- 53.6M
- +9.07M (+20.4%) vs. Q4 2024
- Total value
- $499.5M
- −$119.2M (−19.3%) vs. Q4 2024
- New holders
- 22
- 42 more added
- Sold out
- 16
- 31 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 6 | $0 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 4 | $37 | 0.00% | −15−78.9% | Reduced |
| Rothschild Investment LLC | 5 | $47 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 9 | $84 | 0.00% | +9 | New |
| CoreCap Advisors, LLC | 16 | $149 | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 21 | $195 | 0.00% | 00.0% | Unchanged |
| Coldstream Capital Management Inc | 28 | $260 | 0.00% | +28 | New |
| The PNC Financial Services Group, Inc. | 58 | $539 | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 100 | $1.01K | 0.00% | +100 | New |
| Nisa Investment Advisors, LLC | 149 | $1.39K | 0.00% | +126+547.8% | Added |
| Daiwa Securities Group Inc. | 173 | $2.00K | 0.00% | +173 | New |
| CWM, LLC | 383 | $4.00K | 0.00% | +312+439.4% | Added |
| Federated Hermes, Inc. | 475 | $4.42K | 0.00% | −553−53.8% | Reduced |
| Caitong International Asset Management Co., Ltd | 503 | $4.68K | 0.00% | +503 | New |
| Royal Bank of Canada | 677 | $6.00K | 0.00% | −97−12.5% | Reduced |
| STRS Ohio | 700 | $6.51K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 701 | $7.00K | 0.00% | +277+65.3% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 792 | $7.37K | 0.00% | +792 | New |
| Advisor Group Holdings, Inc. | 835 | $7.76K | 0.00% | +813+3,695.5% | Added |
| GF Fund Management Co. Ltd. | 1,296 | $12.1K | 0.00% | +233+21.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 1,693 | $16.5K | 0.00% | +7+0.4% | Added |
| Ameritas Investment Partners, Inc. | 1,991 | $18.5K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 2,083 | $19.4K | 0.00% | +666+47.0% | Added |
| KLP Kapitalforvaltning AS | 2,200 | $20.5K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 2,273 | $21.1K | 0.00% | +1,712+305.2% | Added |
| Police & Firemen's Retirement System of New Jersey | 5,049 | $47.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 5,435 | $50.5K | 0.00% | +1,823+50.5% | Added |
| New York State Common Retirement Fund | 7,423 | $69.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,047 | $84.1K | 0.00% | +9,047 | New |
| Legal & General Group Plc | 9,261 | $86.1K | 0.00% | −79−0.8% | Reduced |
| Wells Fargo & Company | 9,353 | $87.0K | 0.00% | −140−1.5% | Reduced |
| Corebridge Financial, Inc. | 9,590 | $89.2K | 0.00% | −512−5.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 10,150 | $94.4K | 0.01% | −580−5.4% | Reduced |
| Russell Investments Group, Ltd. | 10,239 | $95.2K | 0.00% | −216−2.1% | Reduced |
| Axq Capital, LP | 10,302 | $95.8K | 0.04% | +10,302 | New |
| California State Teachers Retirement System | 10,570 | $98.3K | 0.00% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 10,607 | $98.6K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 10,818 | $100.6K | 0.03% | +10,818 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 11,514 | $107.1K | 0.00% | −127−1.1% | Reduced |
| Aquatic Capital Management LLC | 11,781 | $109.6K | 0.00% | +7,195+156.9% | Added |
| Exchange Traded Concepts, LLC | 11,861 | $110.3K | 0.00% | +3,550+42.7% | Added |
| Tudor Investment Corp Et Al | 12,093 | $112.5K | 0.00% | −3,484−22.4% | Reduced |
| MetLife Investment Management | 12,207 | $113.5K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 13,597 | $126.5K | 0.00% | +13,597 | New |
| EntryPoint Capital, LLC | 14,892 | $138.5K | 0.06% | −3,317−18.2% | Reduced |
| SG Americas Securities, LLC | 15,120 | $141.0K | 0.00% | +5,449+56.3% | Added |
| Citigroup Inc | 15,507 | $144.2K | 0.00% | −1,296−7.7% | Reduced |
| Deutsche Bank AG | 16,979 | $157.9K | 0.00% | −1,930−10.2% | Reduced |
| Alliancebernstein L.P. | 17,570 | $163.4K | 0.00% | 00.0% | Unchanged |
| Auour Investments LLC | 21,020 | $216.5K | 0.08% | 00.0% | Unchanged |
| American Century Companies Inc | 23,431 | $217.9K | 0.00% | +1,289+5.8% | Added |
| Susquehanna International Group, LLP | 23,526 | $218.8K | 0.00% | +23,526 | New |
| HighVista Strategies LLC | 23,941 | $222.7K | 0.09% | 00.0% | Unchanged |
| Caligan Partners LP | 25,000 | $232.5K | 0.05% | +25,000 | New |
| Jump Financial, LLC | 27,949 | $259.9K | 0.00% | +12,789+84.4% | Added |
| Rhumbline Advisers | 28,081 | $261.1K | 0.00% | +1,879+7.2% | Added |
| Swiss National Bank | 29,400 | $273.4K | 0.00% | +8,700+42.0% | Added |
| Quest Partners LLC | 29,622 | $275.5K | 0.03% | +24,599+489.7% | Added |
| ExodusPoint Capital Management, LP | 30,235 | $281.0K | 0.00% | +30,235 | New |
| Dimensional Fund Advisors LP | 34,712 | $322.8K | 0.00% | −3,269−8.6% | Reduced |
| Jane Street Group, LLC | 34,813 | $323.8K | 0.00% | +34,813 | New |
| Ikarian Capital, LLC | 35,000 | $325.5K | 0.11% | −25,000−41.7% | Reduced |
| UBS Asset Management Americas Inc | 35,635 | $331.4K | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 41,083 | $382.1K | 0.00% | −3,924−8.7% | Reduced |
| Verition Fund Management LLC | 42,174 | $392.2K | 0.00% | +42,174 | New |
| Barclays PLC | 42,511 | $395.4K | 0.00% | −559−1.3% | Reduced |
| UBS Group AG | 46,286 | $430.5K | 0.00% | −1,565−3.3% | Reduced |
| Brevan Howard Capital Management LP | 46,371 | $431.3K | 0.01% | +46,371 | New |
| Point72 Asset Management, L.P. | 49,600 | $461.3K | 0.00% | +36,817+288.0% | Added |
| Nuveen, LLC | 49,998 | $465.0K | 0.00% | +49,998 | New |
| Two Sigma Advisers, LP | 50,100 | $465.9K | 0.00% | +37,800+307.3% | Added |
| Renaissance Technologies LLC | 51,400 | $478.0K | 0.00% | +22,300+76.6% | Added |
| Raymond James Financial Inc | 54,344 | $505.4K | 0.00% | −439−0.8% | Reduced |
| Victory Capital Management Inc | 56,150 | $522.2K | 0.00% | −490−0.9% | Reduced |
| State of Wisconsin Investment Board | 58,712 | $546.0K | 0.00% | −6,327−9.7% | Reduced |
| Two Sigma Investments, LP | 64,818 | $602.8K | 0.00% | +18,549+40.1% | Added |
| BNP Paribas Arbitrage, SA | 68,950 | $641.2K | 0.00% | +64,632+1,496.8% | Added |
| Oppenheimer & Co Inc | 74,805 | $695.7K | 0.01% | −634−0.8% | Reduced |
| Goldman Sachs Group Inc | 78,006 | $725.5K | 0.00% | +13,896+21.7% | Added |
| Bank of America Corp | 83,521 | $776.7K | 0.00% | +17,364+26.2% | Added |
| Investment Counsel Co of Nevada | 85,020 | $790.7K | 1.80% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 85,490 | $795.1K | 0.00% | −5,625−6.2% | Reduced |
| Cubist Systematic Strategies, LLC | 91,844 | $854.1K | 0.01% | −17,904−16.3% | Reduced |
| Citadel Advisors LLC | 96,282 | $895.4K | 0.00% | +40,695+73.2% | Added |
| Woodline Partners LP | 100,108 | $931.0K | 0.01% | +100,108 | New |
| Wellington Management Group LLP | 104,087 | $968.0K | 0.00% | +9,228+9.7% | Added |
| Ally Bridge Group (NY) LLC | 107,244 | $997.4K | 0.90% | −67,819−38.7% | Reduced |
| AXA S.A. | 128,189 | $1.19M | 0.00% | +128,189 | New |
| Walleye Capital LLC | 140,742 | $1.31M | 0.01% | +77,762+123.5% | Added |
| Polar Asset Management Partners Inc. | 141,241 | $1.31M | 0.04% | +30,134+27.1% | Added |
| Charles Schwab Investment Management Inc | 164,108 | $1.53M | 0.00% | −6,492−3.8% | Reduced |
| Morgan Stanley | 180,590 | $1.68M | 0.00% | +106,441+143.6% | Added |
| Northern Trust Corp | 216,447 | $2.01M | 0.00% | −6,317−2.8% | Reduced |
| Balyasny Asset Management LLC | 243,244 | $2.26M | 0.01% | +243,244 | New |
| Jacobs Levy Equity Management, Inc | 301,801 | $2.81M | 0.01% | +57,556+23.6% | Added |
| Marshall Wace, LLP | 380,700 | $3.54M | 0.00% | +326,623+604.0% | Added |
| Millennium Management LLC | 404,165 | $3.76M | 0.00% | +89,024+28.2% | Added |
| State Street Corp | 413,988 | $3.85M | 0.00% | +6,415+1.6% | Added |
| Sio Capital Management, LLC | 416,617 | $3.87M | 1.17% | +175,747+73.0% | Added |
| Pictet Asset Management Holding SA | 459,113 | $4.27M | 0.00% | +105,101+29.7% | Added |