Tyra Biosciences, Inc.
TYRA- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001863127
In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Tyra Biosciences, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 62
- +3 vs. Q3 2023
- Shares held
- 35.8M
- −705.9K (−1.9%) vs. Q3 2023
- Total value
- $495.2M
- −$6.93M (−1.4%) vs. Q3 2023
- New holders
- 9
- 21 more added
- Sold out
- 6
- 12 more reduced
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting TYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 168 | $2.22B |
| Q1 2026 | 164 | $2.52B |
| Q4 2025 | 133 | $1.49B |
| Q3 2025 | 116 | $778.4M |
| Q2 2025 | 121 | $541.5M |
| Q1 2025 | 117 | $499.5M |
| Q4 2024 | 113 | $675.8M |
| Q3 2024 | 95 | $1.11B |
| Q2 2024 | 79 | $748.6M |
| Q1 2024 | 77 | $768.4M |
| Q4 2023 | 62 | $495.2M |
| Q3 2023 | 59 | $502.1M |
| Q2 2023 | 59 | $616.7M |
| Q1 2023 | 51 | $573.0M |
| Q4 2022 | 46 | $267.8M |
| Q3 2022 | 49 | $313.8M |
| Q2 2022 | 48 | $255.6M |
| Q1 2022 | 46 | $386.6M |
| Q4 2021 | 45 | $494.2M |
| Q3 2021 | 26 | $456.8M |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Tyra Biosciences, Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| GAMMA Investing LLC | 16 | $214 | 0.00% | +16 | New |
| Nisa Investment Advisors, LLC | 16 | $222 | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 19 | $263 | 0.00% | 00.0% | Unchanged |
| The PNC Financial Services Group, Inc. | 58 | $803 | 0.00% | 00.0% | Unchanged |
| Metropolitan Life Insurance Co | 814 | $11.3K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 940 | $13.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 1,004 | $13.9K | 0.00% | +146+17.0% | Added |
| Legal & General Group Plc | 1,265 | $17.6K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 1,445 | $20.0K | 0.00% | −126−8.0% | Reduced |
| Citigroup Inc | 2,031 | $28.1K | 0.00% | +2,012+10,589.5% | Added |
| Federated Hermes, Inc. | 2,070 | $28.7K | 0.00% | +1,916+1,244.2% | Added |
| California State Teachers Retirement System | 2,302 | $31.9K | 0.00% | −784−25.4% | Reduced |
| Qube Research & Technologies Ltd | 2,653 | $36.7K | 0.00% | +2,653 | New |
| New York State Common Retirement Fund | 4,031 | $55.8K | 0.00% | −15−0.4% | Reduced |
| Wells Fargo & Company | 4,073 | $56.4K | 0.00% | +843+26.1% | Added |
| Royal Bank of Canada | 4,244 | $58.0K | 0.00% | +2,110+98.9% | Added |
| AJOVista, LLC | 4,235 | $58.7K | 0.07% | +4,235 | New |
| UBS Group AG | 4,977 | $68.9K | 0.00% | −333−6.3% | Reduced |
| Deutsche Bank AG | 6,223 | $86.2K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 6,951 | $96.3K | 0.00% | −29−0.4% | Reduced |
| MetLife Investment Management | 7,702 | $106.7K | 0.00% | 00.0% | Unchanged |
| Acuta Capital Partners, LLC | 8,867 | $122.8K | 0.07% | +8,867 | New |
| Exchange Traded Concepts, LLC | 9,531 | $132.0K | 0.00% | +2,417+34.0% | Added |
| Artia Global Partners LP | 10,253 | $142.0K | 0.06% | −35,000−77.3% | Reduced |
| LPL Financial LLC | 10,500 | $145.4K | 0.00% | −4,000−27.6% | Reduced |
| Baker Bros. Advisors LP | 10,607 | $146.9K | 0.00% | +10,607 | New |
| Dimensional Fund Advisors LP | 10,609 | $146.9K | 0.00% | 00.0% | Unchanged |
| Sepio Capital, LP | 10,625 | $147.2K | 0.01% | 00.0% | Unchanged |
| American Century Companies Inc | 10,880 | $150.7K | 0.00% | +10,880 | New |
| Barclays PLC | 19,227 | $266.3K | 0.00% | +16,721+667.2% | Added |
| Rhumbline Advisers | 21,332 | $295.4K | 0.00% | −129−0.6% | Reduced |
| Bank of America Corp | 22,118 | $306.3K | 0.00% | −46−0.2% | Reduced |
| Mariner, LLC | 22,164 | $307.0K | 0.00% | −2,132−8.8% | Reduced |
| Nuveen Asset Management, LLC | 25,713 | $356.1K | 0.00% | +6,957+37.1% | Added |
| Marshall Wace, LLP | 30,001 | $415.5K | 0.00% | +30,001 | New |
| Morgan Stanley | 35,668 | $494.0K | 0.00% | +17,384+95.1% | Added |
| Bank of New York Mellon Corp | 41,945 | $580.9K | 0.00% | +75+0.2% | Added |
| Ikarian Capital, LLC | 48,170 | $667.2K | 0.18% | 00.0% | Unchanged |
| Victory Capital Management Inc | 50,220 | $695.5K | 0.00% | +17,490+53.4% | Added |
| Auour Investments LLC | 85,020 | $1.14M | 0.45% | 00.0% | Unchanged |
| Wellington Management Group LLP | 102,436 | $1.42M | 0.00% | +8,324+8.8% | Added |
| Charles Schwab Investment Management Inc | 110,537 | $1.53M | 0.00% | +323+0.3% | Added |
| EcoR1 Capital, LLC | 137,014 | $1.90M | 0.05% | +137,014 | New |
| Northern Trust Corp | 152,250 | $2.11M | 0.00% | +10,651+7.5% | Added |
| Driehaus Capital Management LLC | 203,709 | $2.82M | 0.03% | +53,241+35.4% | Added |
| State Street Corp | 265,354 | $3.68M | 0.00% | +5,896+2.3% | Added |
| Geode Capital Management, LLC | 333,469 | $4.62M | 0.00% | +18,991+6.0% | Added |
| Kynam Capital Management, LP | 340,190 | $4.71M | 0.53% | +340,190 | New |
| Perceptive Advisors LLC | 360,000 | $4.99M | 0.11% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 401,706 | $5.56M | 0.00% | +4,088+1.0% | Added |
| 5AM Venture Management, LLC | 554,979 | $7.69M | 2.04% | +143,529+34.9% | Added |
| Vanguard Group Inc | 758,967 | $10.5M | 0.00% | +26,383+3.6% | Added |
| BlackRock Inc. | 965,034 | $13.4M | 0.00% | +68,582+7.7% | Added |
| Frazier Life Sciences Management, L.P. | 1,026,420 | $14.2M | 0.76% | −1,593−0.2% | Reduced |
| Fairmount Funds Management LLC | 1,393,329 | $19.3M | 2.04% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 1,989,103 | $27.5M | 3.06% | 00.0% | Unchanged |
| Nextech Invest AG | 2,518,582 | $34.9M | 6.50% | 00.0% | Unchanged |
| BVF Inc | 2,739,595 | $37.9M | 0.95% | 00.0% | Unchanged |
| FMR LLC | 2,768,696 | $38.3M | 0.00% | −1,130,131−29.0% | Reduced |
| Canaan Partners XI LLC | 4,409,991 | $61.1M | 76.34% | 00.0% | Unchanged |
| Boxer Capital, LLC | 6,448,359 | $89.3M | 4.45% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 7,236,454 | $100.2M | 1.57% | 00.0% | Unchanged |
| Woodline Partners LP | 0 | $0 | 0.00% | −410,435−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −31,872−100.0% | Sold out |
| Parkwood LLC | 0 | $0 | 0.00% | −16,967−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −11,872−100.0% | Sold out |
| Corton Capital Inc. | 0 | $0 | 0.00% | −11,009−100.0% | Sold out |
| Simplex Trading, LLC | 0 | $0 | 0.00% | −2,009−100.0% | Sold out |