Rhythm Pharmaceuticals, Inc.
RYTM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001649904
In the last 90 days, Rhythm Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 6 sales; 304 institutions reported holding it in 13F filings for Q2 2026, worth $8.55B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Rhythm Pharmaceuticals, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 285
- +10 vs. Q4 2025
- Shares held
- 73.6M
- +6.99M (+10.5%) vs. Q4 2025
- Total value
- $6.42B
- −$704.3M (−9.9%) vs. Q4 2025
- New holders
- 63
- 102 more added
- Sold out
- 53
- 89 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting RYTM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 304 | $8.55B |
| Q1 2026 | 285 | $6.42B |
| Q4 2025 | 281 | $7.80B |
| Q3 2025 | 264 | $7.20B |
| Q2 2025 | 227 | $4.20B |
| Q1 2025 | 228 | $3.44B |
| Q4 2024 | 203 | $3.63B |
| Q3 2024 | 176 | $3.55B |
| Q2 2024 | 165 | $2.85B |
| Q1 2024 | 167 | $2.95B |
| Q4 2023 | 169 | $3.07B |
| Q3 2023 | 144 | $1.56B |
| Q2 2023 | 116 | $1.09B |
| Q1 2023 | 126 | $1.08B |
| Q4 2022 | 115 | $1.81B |
| Q3 2022 | 101 | $1.45B |
| Q2 2022 | 90 | $190.8M |
| Q1 2022 | 111 | $562.7M |
| Q4 2021 | 98 | $483.6M |
| Q3 2021 | 97 | $626.3M |
| Q2 2021 | 105 | $905.6M |
| Q1 2021 | 124 | $1.01B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Rhythm Pharmaceuticals, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Inceptionr LLC | 4,379 | $380.8K | 0.09% | +4,379 | New |
| E. Ohman J:or Asset Management AB | 4,409 | $383.5K | 0.01% | −2,180−33.1% | Reduced |
| Nelson, Van Denburg & Campbell Wealth Management Group, LLC | 4,650 | $404.4K | 0.01% | +1,078+30.2% | Added |
| Rockefeller Capital Management L.P. | 4,844 | $421.3K | 0.00% | −6,927−58.8% | Reduced |
| Gotham Asset Management, LLC | 4,848 | $421.6K | 0.00% | −3−0.1% | Reduced |
| Xponance, Inc. | 4,990 | $434.0K | 0.00% | +721+16.9% | Added |
| Fifth Third Bancorp | 5,260 | $457.5K | 0.00% | +5,260 | New |
| Public Employees Retirement Association of Colorado | 5,463 | $475.0K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 5,637 | $490.3K | 0.00% | −561−9.1% | Reduced |
| Blueshift Asset Management, LLC | 5,787 | $503.3K | 0.15% | +2,906+100.9% | Added |
| Great West Life Assurance Co | 5,797 | $507.0K | 0.00% | 00.0% | Unchanged |
| Campbell & CO Investment Adviser LLC | 5,958 | $518.2K | 0.03% | +5,958 | New |
| Texas Treasury Safekeeping Trust Co | 6,154 | $535.0K | 0.09% | +6,154 | New |
| LPL Financial LLC | 6,198 | $539.0K | 0.00% | +771+14.2% | Added |
| E Fund Management Co., Ltd. | 6,453 | $561.2K | 0.02% | +6,453 | New |
| IMC-Chicago, LLC | 6,697 | $582.4K | 0.01% | +6,697 | New |
| The PNC Financial Services Group, Inc. | 6,938 | $603.4K | 0.00% | +2,279+48.9% | Added |
| Teacher Retirement System of Texas | 7,330 | $637.5K | 0.00% | −1,029−12.3% | Reduced |
| Virtus Investment Advisers, Inc. | 7,434 | $646.5K | 0.18% | +1,417+23.5% | Added |
| Tower Research Capital LLC (TRC) | 7,715 | $671.0K | 0.02% | +4,753+160.5% | Added |
| Prelude Capital Management, LLC | 8,372 | $728.1K | 0.06% | +8,372 | New |
| Exchange Traded Concepts, LLC | 8,463 | $736.0K | 0.01% | +2,383+39.2% | Added |
| CenterBook Partners LP | 9,026 | $785.0K | 0.04% | +9,026 | New |
| HighTower Advisors, LLC | 9,058 | $787.8K | 0.00% | +9,058 | New |
| Hudson Bay Capital Management LP | 9,120 | $793.2K | 0.00% | +9,120 | New |
| Los Angeles Capital Management LLC | 9,219 | $801.8K | 0.00% | −15,115−62.1% | Reduced |
| AlphaCentric Advisors LLC | 9,297 | $808.6K | 0.81% | +4,245+84.0% | Added |
| Marshall Wace, LLP | 9,628 | $837.3K | 0.00% | +9,628 | New |
| Toth Financial Advisory Corp | 10,000 | $869.7K | 0.10% | 00.0% | Unchanged |
| Cannon Financial Strategists, Inc. | 10,000 | $869.7K | 0.11% | 00.0% | Unchanged |
| Entropy Technologies, LP | 10,318 | $897.4K | 0.04% | +7,826+314.0% | Added |
| Barclays PLC | 10,652 | $926.4K | 0.00% | −120,784−91.9% | Reduced |
| ProShare Advisors LLC | 10,720 | $932.3K | 0.00% | −1,902−15.1% | Reduced |
| DnB Asset Management AS | 11,195 | $973.6K | 0.00% | +32+0.3% | Added |
| China Universal Asset Management Co., Ltd. | 12,118 | $1.05M | 0.08% | +1,243+11.4% | Added |
| Citigroup Inc | 12,336 | $1.07M | 0.00% | −384−3.0% | Reduced |
| Stifel Financial Corp | 12,339 | $1.07M | 0.00% | −908−6.9% | Reduced |
| Bridgefront Capital, LLC | 12,495 | $1.09M | 0.27% | +12,495 | New |
| KLP Kapitalforvaltning AS | 12,500 | $1.09M | 0.00% | +500+4.2% | Added |
| Intech Investment Management LLC | 13,739 | $1.19M | 0.01% | −7,611−35.6% | Reduced |
| Jasper Ridge Partners, L.P. | 13,845 | $1.20M | 0.03% | +8,206+145.5% | Added |
| Vanguard Investments Australia, Ltd. | 13,927 | $1.21M | 0.00% | +13,927 | New |
| HSBC Holdings PLC | 14,307 | $1.22M | 0.00% | +14,307 | New |
| Police & Firemen's Retirement System of New Jersey | 14,594 | $1.27M | 0.01% | +411+2.9% | Added |
| State Board of Administration of Florida Retirement System | 14,650 | $1.27M | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 15,581 | $1.36M | 0.01% | −181−1.1% | Reduced |
| Knights of Columbus Asset Advisors LLC | 15,589 | $1.36M | 0.08% | +5,275+51.1% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 15,598 | $1.36M | 0.00% | +3,163+25.4% | Added |
| Guggenheim Capital LLC | 16,554 | $1.44M | 0.01% | +4,153+33.5% | Added |
| HighVista Strategies LLC | 16,796 | $1.46M | 0.40% | −26,071−60.8% | Reduced |
| Handelsbanken Fonder AB | 17,521 | $1.52M | 0.01% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 17,775 | $1.55M | 0.02% | −57,366−76.3% | Reduced |
| Captrust Financial Advisors | 18,147 | $1.58M | 0.00% | −178−1.0% | Reduced |
| Advisors Asset Management, Inc. | 18,718 | $1.63M | 0.03% | +194+1.0% | Added |
| SG Americas Securities, LLC | 18,760 | $1.63M | 0.00% | +7,019+59.8% | Added |
| Dimensional Fund Advisors LP | 19,151 | $1.67M | 0.00% | −12,867−40.2% | Reduced |
| State of New Jersey Common Pension Fund D | 19,386 | $1.69M | 0.01% | +116+0.6% | Added |
| Tudor Investment Corp Et Al | 19,646 | $1.71M | 0.01% | +19,646 | New |
| Victory Capital Management Inc | 20,504 | $1.78M | 0.00% | −24,877−54.8% | Reduced |
| Liberty Mutual Group Asset Management Inc. | 20,514 | $1.78M | 0.14% | +20,514 | New |
| Creative Planning | 21,085 | $1.83M | 0.00% | −4,121−16.3% | Reduced |
| Mutual of America Capital Management LLC | 22,529 | $1.96M | 0.02% | +22,529 | New |
| Profund Advisors LLC | 22,787 | $1.98M | 0.07% | +1,741+8.3% | Added |
| Wedge Capital Management L L P | 24,535 | $2.13M | 0.04% | +5,288+27.5% | Added |
| PDT Partners, LLC | 27,232 | $2.37M | 0.14% | −32,204−54.2% | Reduced |
| MetLife Investment Management | 28,889 | $2.51M | 0.01% | −285−1.0% | Reduced |
| STRS Ohio | 28,914 | $2.51M | 0.01% | +16,914+141.0% | Added |
| Aquatic Capital Management LLC | 29,671 | $2.58M | 0.07% | +29,671 | New |
| Vanguard Global Advisers, LLC | 29,700 | $2.58M | 0.00% | +29,700 | New |
| Prudential Financial Inc | 30,190 | $2.63M | 0.00% | −22,955−43.2% | Reduced |
| Harbor Capital Advisors, Inc. | 30,353 | $2.64M | 0.21% | −10,543−25.8% | Reduced |
| Alyeska Investment Group, L.P. | 32,589 | $2.83M | 0.01% | +32,589 | New |
| D. E. Shaw & Co., Inc. | 32,652 | $2.84M | 0.00% | +1,296+4.1% | Added |
| Lazard Asset Management LLC | 32,888 | $2.86M | 0.00% | +7,317+28.6% | Added |
| Aspiriant, LLC | 33,007 | $2.87M | 0.08% | +33,007 | New |
| Wells Fargo & Company | 34,108 | $2.97M | 0.00% | −38,509−53.0% | Reduced |
| EFG International AG | 34,214 | $2.98M | 0.06% | +4,923+16.8% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 34,677 | $2.98M | 0.00% | −224−0.6% | Reduced |
| State of Wisconsin Investment Board | 36,571 | $3.18M | 0.01% | +492+1.4% | Added |
| TD Asset Management Inc | 38,778 | $3.37M | 0.00% | −16,272−29.6% | Reduced |
| Hillsdale Investment Management Inc. | 40,300 | $3.50M | 0.10% | −2,000−4.7% | Reduced |
| Exome Asset Management LLC | 40,581 | $3.53M | 2.08% | +40,581 | New |
| SEI Investments Co | 40,685 | $3.54M | 0.00% | +3,253+8.7% | Added |
| Utah Retirement Systems | 42,177 | $3.67M | 0.04% | +42,177 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 43,872 | $3.82M | 0.00% | +41,457+1,716.6% | Added |
| Silvercrest Asset Management Group LLC | 46,887 | $4.08M | 0.03% | +12,760+37.4% | Added |
| Legal & General Group Plc | 47,032 | $4.09M | 0.00% | −8,043−14.6% | Reduced |
| Harvest Investment Services, LLC | 48,468 | $4.22M | 0.77% | +4,515+10.3% | Added |
| Nan Fung Group Holdings Ltd | 49,120 | $4.27M | 3.52% | 00.0% | Unchanged |
| Vanguard Asset Management, Ltd | 49,689 | $4.32M | 0.00% | +49,689 | New |
| Raymond James Financial Inc | 49,920 | $4.34M | 0.00% | +8,805+21.4% | Added |
| Rafferty Asset Management, LLC | 50,105 | $4.36M | 0.02% | −5,421−9.8% | Reduced |
| Picton Mahoney Asset Management | 50,372 | $4.38M | 0.05% | +50,372 | New |
| Manufacturers Life Insurance Company, The | 50,769 | $4.42M | 0.00% | −8,840−14.8% | Reduced |
| Susquehanna International Group, LLP | 50,784 | $4.42M | 0.01% | +46,687+1,139.5% | Added |
| Castleark Management LLC | 52,279 | $4.55M | 0.15% | −12,200−18.9% | Reduced |
| Balyasny Asset Management LLC | 52,967 | $4.61M | 0.01% | −19,315−26.7% | Reduced |
| Atom Investors LP | 57,000 | $4.96M | 0.35% | +34,071+148.6% | Added |
| Algert Global LLC | 58,513 | $5.09M | 0.08% | −29,737−33.7% | Reduced |
| AQR Capital Management LLC | 59,279 | $5.16M | 0.00% | −10,767−15.4% | Reduced |