Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 291
- +48 vs. Q4 2025
- Shares held
- 31.8M
- +3.79M (+13.5%) vs. Q4 2025
- Total value
- $10.2B
- +$1.98B (+24.0%) vs. Q4 2025
- New holders
- 80
- 121 more added
- Sold out
- 32
- 68 more reduced
7 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Congress Asset Management Co | 24,839 | $8.00M | 0.06% | −6,407−20.5% | Reduced |
| University of Wisconsin Foundation | 25,215 | $8.12M | 7.21% | +25,215 | New |
| Alliancebernstein L.P. | 27,700 | $8.16M | 0.00% | +2,630+10.5% | Added |
| Neuberger Berman Group LLC | 25,960 | $8.36M | 0.01% | +282+1.1% | Added |
| HighVista Strategies LLC | 26,323 | $8.48M | 2.34% | +482+1.9% | Added |
| California State Teachers Retirement System | 27,477 | $8.85M | 0.01% | +7,806+39.7% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 27,744 | $8.89M | 0.01% | +2,185+8.5% | Added |
| Voya Investment Management LLC | 28,134 | $9.06M | 0.01% | +14,479+106.0% | Added |
| SEI Investments Co | 29,525 | $9.51M | 0.01% | +13,729+86.9% | Added |
| Lord, Abbett & Co. LLC | 29,619 | $9.54M | 0.03% | −1,137−3.7% | Reduced |
| Manufacturers Life Insurance Company, The | 30,093 | $9.70M | 0.01% | −3,198−9.6% | Reduced |
| Prudential Financial Inc | 30,510 | $9.83M | 0.01% | +15,648+105.3% | Added |
| Dimensional Fund Advisors LP | 31,161 | $10.0M | 0.00% | +7,618+32.4% | Added |
| Ameriprise Financial Inc | 31,220 | $10.1M | 0.00% | +8,505+37.4% | Added |
| Ally Bridge Group (NY) LLC | 32,810 | $10.6M | 10.50% | +12,928+65.0% | Added |
| Rhumbline Advisers | 32,879 | $10.6M | 0.01% | +4,555+16.1% | Added |
| B Group, Inc. | 33,237 | $10.7M | 7.94% | 00.0% | Unchanged |
| First Trust Advisors LP | 33,335 | $10.7M | 0.01% | −55,369−62.4% | Reduced |
| Burkehill Global Management, LP | 35,000 | $11.3M | 0.56% | +10,000+40.0% | Added |
| TD Asset Management Inc | 35,146 | $11.3M | 0.01% | −11,000−23.8% | Reduced |
| PFM Health Sciences, LP | 35,438 | $11.4M | 1.20% | +4,275+13.7% | Added |
| SummitTX Capital, L.P. | 36,838 | $11.9M | 0.38% | −4,791−11.5% | Reduced |
| UBS Asset Management Americas Inc | 38,145 | $12.3M | 0.00% | +2,857+8.1% | Added |
| Eventide Asset Management, LLC | 38,640 | $12.4M | 0.21% | −28,460−42.4% | Reduced |
| Integral Health Asset Management, LLC | 40,000 | $12.9M | 0.68% | 00.0% | Unchanged |
| Canada Pension Plan Investment Board | 40,130 | $12.9M | 0.01% | −29,582−42.4% | Reduced |
| California Public Employees Retirement System | 42,163 | $13.6M | 0.01% | +42,163 | New |
| First Turn Management, LLC | 42,441 | $13.7M | 1.53% | +6,692+18.7% | Added |
| KVP Capital Advisors, LP | 42,900 | $13.8M | 10.32% | 00.0% | Unchanged |
| Marshall Wace, LLP | 45,149 | $14.5M | 0.02% | −24,093−34.8% | Reduced |
| Exome Asset Management LLC | 45,469 | $14.6M | 8.62% | −12,653−21.8% | Reduced |
| Boxer Capital Management, LLC | 46,457 | $15.0M | 1.97% | 00.0% | Unchanged |
| Swiss National Bank | 46,700 | $15.0M | 0.01% | +6,200+15.3% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 47,432 | $15.3M | 0.03% | +10,055+26.9% | Added |
| Frontier Capital Management Co LLC | 53,365 | $17.2M | 0.18% | +53,365 | New |
| StemPoint Capital LP | 56,267 | $18.1M | 3.48% | +35,200+167.1% | Added |
| Deutsche Bank AG | 57,779 | $18.6M | 0.01% | +6,968+13.7% | Added |
| AQR Capital Management LLC | 58,656 | $18.9M | 0.01% | +29,828+103.5% | Added |
| Invesco Ltd. | 61,397 | $19.8M | 0.00% | −15,691−20.4% | Reduced |
| Candriam Luxembourg S.C.A. | 63,628 | $20.5M | 0.11% | −46,962−42.5% | Reduced |
| Sofinnova Investments, Inc. | 63,680 | $20.5M | 1.03% | −62,042−49.3% | Reduced |
| 72 Investment Holdings, LLC | 65,933 | $21.2M | 42.83% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 68,383 | $22.0M | 0.04% | +4,100+6.4% | Added |
| JPMorgan Chase & Co | 80,180 | $22.2M | 0.00% | +24,880+45.0% | Added |
| Silverarc Capital Management, LLC | 71,552 | $23.1M | 2.72% | −10,913−13.2% | Reduced |
| Ikarian Capital, LLC | 71,581 | $23.1M | 3.30% | −15,000−17.3% | Reduced |
| Nuveen, LLC | 72,043 | $23.2M | 0.01% | +22,073+44.2% | Added |
| Alyeska Investment Group, L.P. | 72,178 | $23.3M | 0.07% | −2,198−3.0% | Reduced |
| MetLife Investment Management | 80,930 | $26.1M | 0.13% | +68,506+551.4% | Added |
| Acuta Capital Partners, LLC | 84,901 | $27.4M | 19.46% | +1,865+2.2% | Added |
| Bank of New York Mellon Corp | 87,047 | $28.0M | 0.01% | +9,150+11.7% | Added |
| Velan Capital Investment Management LP | 100,781 | $32.5M | 20.34% | 00.0% | Unchanged |
| UBS Group AG | 108,446 | $34.9M | 0.01% | +19,246+21.6% | Added |
| ArrowMark Colorado Holdings LLC | 117,851 | $38.0M | 1.01% | +87,851+292.8% | Added |
| Qube Research & Technologies Ltd | 128,228 | $41.3M | 0.06% | −40,669−24.1% | Reduced |
| American Century Companies Inc | 128,254 | $41.3M | 0.02% | +52,888+70.2% | Added |
| BNP Paribas Arbitrage, SA | 143,082 | $46.1M | 0.03% | +138,456+2,993.0% | Added |
| Vanguard Fiduciary Trust Co | 169,902 | $54.7M | 0.01% | +169,902 | New |
| Affinity Asset Advisors, LLC | 170,000 | $54.8M | 3.21% | −15,000−8.1% | Reduced |
| Standard Life Aberdeen plc | 172,484 | $55.6M | 0.09% | +37,492+27.8% | Added |
| OrbiMed Advisors LLC | 172,500 | $55.6M | 1.26% | +78,000+82.5% | Added |
| Wellington Management Group LLP | 174,350 | $56.2M | 0.01% | −2,212−1.3% | Reduced |
| T. Rowe Price Investment Management, Inc. | 175,237 | $56.5M | 0.04% | −101,155−36.6% | Reduced |
| Woodline Partners LP | 200,013 | $64.4M | 0.24% | +94,601+89.7% | Added |
| Charles Schwab Investment Management Inc | 215,447 | $69.4M | 0.01% | +17,146+8.6% | Added |
| Northern Trust Corp | 227,934 | $73.4M | 0.01% | +35,650+18.5% | Added |
| Franklin Resources Inc | 276,123 | $89.0M | 0.02% | −79,951−22.5% | Reduced |
| Pictet Asset Management Holding SA | 286,644 | $91.4M | 0.10% | +46,056+19.1% | Added |
| Logos Global Management LP | 285,000 | $91.8M | 4.73% | −90,000−24.0% | Reduced |
| Soleus Capital Management, L.P. | 330,517 | $106.5M | 4.31% | −32,449−8.9% | Reduced |
| Vivo Capital, LLC | 338,895 | $109.2M | 9.08% | +10,000+3.0% | Added |
| Hood River Capital Management LLC | 358,618 | $115.5M | 1.16% | +69,151+23.9% | Added |
| Ra Capital Management, L.P. | 373,787 | $120.4M | 1.28% | 00.0% | Unchanged |
| Bank of America Corp | 534,604 | $172.2M | 0.01% | +11,841+2.3% | Added |
| Price T Rowe Associates Inc | 630,852 | $203.3M | 0.02% | −155,135−19.7% | Reduced |
| Geode Capital Management, LLC | 650,904 | $209.8M | 0.01% | +88,525+15.7% | Added |
| Goldman Sachs Group Inc | 710,734 | $229.0M | 0.03% | −5,450−0.8% | Reduced |
| Vanguard Portfolio Management LLC | 756,748 | $243.8M | 0.01% | +756,748 | New |
| Adage Capital Partners GP, L.L.C. | 815,739 | $262.8M | 0.41% | −149,574−15.5% | Reduced |
| Morgan Stanley | 833,491 | $268.5M | 0.02% | −56,398−6.3% | Reduced |
| State Street Corp | 884,238 | $284.9M | 0.01% | +2,023+0.2% | Added |
| Cormorant Asset Management, LP | 885,500 | $285.3M | 14.38% | −64,500−6.8% | Reduced |
| Driehaus Capital Management LLC | 949,225 | $305.8M | 2.25% | +16,164+1.7% | Added |
| Deerfield Management Company, L.P. (Series C) | 963,351 | $310.4M | 3.66% | +60,000+6.6% | Added |
| Vanguard Capital Management LLC | 1,221,944 | $393.7M | 0.01% | +1,221,944 | New |
| Baker Bros. Advisors LP | 1,753,198 | $564.9M | 3.24% | +626,710+55.6% | Added |
| Perceptive Advisors LLC | 2,035,986 | $656.0M | 12.96% | +40,000+2.0% | Added |
| FMR LLC | 2,160,943 | $696.2M | 0.04% | +802,268+59.0% | Added |
| BlackRock, Inc. | 2,324,929 | $749.1M | 0.01% | +246,429+11.9% | Added |
| Orbis Allan Gray Ltd | 2,472,480 | $796.6M | 3.36% | +1,217,318+97.0% | Added |
| Janus Henderson Group PLC | 3,458,863 | $1.11B | 0.53% | +218,777+6.8% | Added |
| Activest Wealth Management | 0 | $0 | 0.00% | −68−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −492,346−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −408,787−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −66,230−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −37,481−100.0% | Sold out |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −36,852−100.0% | Sold out |
| Readystate Asset Management LP | 0 | $0 | 0.00% | −36,792−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −34,917−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −33,300−100.0% | Sold out |