Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 250
- +100 vs. Q3 2025
- Shares held
- 29.5M
- +4.80M (+19.5%) vs. Q3 2025
- Total value
- $8.69B
- +$7.38B (+564.4%) vs. Q3 2025
- New holders
- 115
- 87 more added
- Sold out
- 15
- 44 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ally Bridge Group (NY) LLC | 19,882 | $5.86M | 9.30% | +19,882 | New |
| California State Teachers Retirement System | 19,671 | $5.80M | 0.01% | +1,088+5.9% | Added |
| Legal & General Group Plc | 17,981 | $5.30M | 0.00% | +1,157+6.9% | Added |
| Atom Investors LP | 16,487 | $4.86M | 0.39% | +16,487 | New |
| Prelude Capital Management, LLC | 16,038 | $4.73M | 0.35% | −12,064−42.9% | Reduced |
| Tudor Investment Corp Et Al | 16,009 | $4.72M | 0.03% | +16,009 | New |
| SEI Investments Co | 15,796 | $4.66M | 0.00% | +15,796 | New |
| State of Wisconsin Investment Board | 15,231 | $4.49M | 0.01% | +6,198+68.6% | Added |
| Eagle Health Investments LP | 14,951 | $4.41M | 0.97% | +14,951 | New |
| Prudential Financial Inc | 14,862 | $4.38M | 0.01% | +14,862 | New |
| Voya Investment Management LLC | 13,655 | $4.02M | 0.00% | +13,655 | New |
| Victory Capital Management Inc | 13,298 | $3.92M | 0.00% | +13,298 | New |
| MetLife Investment Management | 12,424 | $3.66M | 0.02% | +1,904+18.1% | Added |
| Erste Asset Management GmbH | 10,500 | $3.20M | 0.03% | +10,500 | New |
| Creative Planning | 10,843 | $3.20M | 0.00% | +4,183+62.8% | Added |
| Jacobs Levy Equity Management, Inc | 10,140 | $2.99M | 0.01% | −3,758−27.0% | Reduced |
| SG Americas Securities, LLC | 9,965 | $2.94M | 0.00% | −3,531−26.2% | Reduced |
| Intech Investment Management LLC | 8,734 | $2.57M | 0.02% | +980+12.6% | Added |
| Profund Advisors LLC | 8,455 | $2.49M | 0.08% | +376+4.7% | Added |
| Hussman Strategic Advisors, Inc. | 8,400 | $2.48M | 0.60% | −2,100−20.0% | Reduced |
| Trexquant Investment LP | 8,331 | $2.46M | 0.02% | −574−6.4% | Reduced |
| Nisa Investment Advisors, LLC | 7,770 | $2.29M | 0.01% | +641+9.0% | Added |
| New York State Common Retirement Fund | 7,300 | $2.15M | 0.00% | +700+10.6% | Added |
| State of New Jersey Common Pension Fund D | 7,018 | $2.07M | 0.01% | +7,018 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 6,870 | $2.02M | 0.01% | +6,870 | New |
| Glenmede Trust Co NA | 6,288 | $1.85M | 0.01% | +6,288 | New |
| Police & Firemen's Retirement System of New Jersey | 6,057 | $1.79M | 0.01% | +1,142+23.2% | Added |
| State Board of Administration of Florida Retirement System | 5,806 | $1.71M | 0.00% | −619−9.6% | Reduced |
| Arizona State Retirement System | 5,723 | $1.69M | 0.01% | +306+5.6% | Added |
| Citigroup Inc | 5,586 | $1.65M | 0.00% | +2,779+99.0% | Added |
| Envestnet Asset Management Inc | 5,550 | $1.64M | 0.00% | +5,550 | New |
| J. Goldman & Co LP | 5,550 | $1.64M | 0.06% | +5,550 | New |
| Group One Trading, L.P. | 5,539 | $1.63M | 0.05% | −11,089−66.7% | Reduced |
| Raymond James Financial Inc | 5,235 | $1.54M | 0.00% | +5,235 | New |
| ProShare Advisors LLC | 5,214 | $1.54M | 0.00% | +1,388+36.3% | Added |
| China Universal Asset Management Co., Ltd. | 4,875 | $1.44M | 0.11% | +1,186+32.1% | Added |
| BNP Paribas Arbitrage, SA | 4,626 | $1.36M | 0.00% | +241+5.5% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 4,587 | $1.35M | 0.00% | +4,587 | New |
| Vestmark Advisory Solutions, Inc. | 4,505 | $1.33M | 0.02% | +4,505 | New |
| Lion Point Capital, LP | 4,450 | $1.31M | 6.79% | −1,250−21.9% | Reduced |
| KLP Kapitalforvaltning AS | 4,400 | $1.30M | 0.01% | +400+10.0% | Added |
| Norges Bank | 4,354 | $1.28M | 0.00% | +4,354 | New |
| Coastal Bridge Advisors, LLC | 4,154 | $1.22M | 0.09% | +308+8.0% | Added |
| Quarry LP | 4,000 | $1.18M | 0.19% | −16,001−80.0% | Reduced |
| Cerity Partners LLC | 3,927 | $1.16M | 0.00% | −1,523−27.9% | Reduced |
| Walleye Capital LLC | 3,587 | $1.06M | 0.01% | +3,587 | New |
| Virginia Retirement Systems Et Al | 3,500 | $1.03M | 0.01% | −400−10.3% | Reduced |
| Royal Bank of Canada | 3,378 | $995.0K | 0.00% | −578−14.6% | Reduced |
| Massachusetts Financial Services Co | 3,316 | $977.4K | 0.00% | +3,316 | New |
| Public Sector Pension Investment Board | 3,297 | $971.8K | 0.00% | +3,297 | New |
| STRS Ohio | 3,200 | $943.2K | 0.00% | +3,200 | New |
| Teacher Retirement System of Texas | 3,053 | $899.8K | 0.00% | −1,416−31.7% | Reduced |
| Quantinno Capital Management LP | 2,723 | $802.6K | 0.00% | +2,723 | New |
| Seven Fleet Capital Management LP | 2,700 | $795.8K | 0.54% | +2,700 | New |
| Artia Global Partners LP | 2,500 | $736.9K | 0.12% | +2,500 | New |
| Allianz Asset Management GmbH | 2,400 | $707.4K | 0.00% | +2,400 | New |
| Public Employees Retirement Association of Colorado | 2,390 | $704.0K | 0.00% | +2,173+1,001.4% | Added |
| Susquehanna International Group, LLP | 2,343 | $690.6K | 0.00% | −26,994−92.0% | Reduced |
| Skopos Labs, Inc. | 2,179 | $663.7K | 0.03% | +2,179 | New |
| Ethic Inc. | 2,193 | $646.4K | 0.01% | +2,193 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 2,082 | $613.6K | 0.09% | +2,082 | New |
| Quinn Opportunity Partners LLC | 2,000 | $589.5K | 0.03% | +2,000 | New |
| Brinker Capital Investments, LLC | 1,985 | $585.1K | 0.00% | +1,985 | New |
| PSP Research LLC | 1,982 | $584.2K | 0.51% | +1,982 | New |
| Squarepoint Ops LLC | 1,890 | $557.1K | 0.00% | +1,890 | New |
| Ameritas Investment Partners, Inc. | 1,866 | $550.0K | 0.02% | +347+22.8% | Added |
| Y-Intercept (Hong Kong) Ltd | 1,856 | $547.0K | 0.01% | −30,330−94.2% | Reduced |
| US Bancorp | 1,825 | $537.9K | 0.00% | +1,713+1,529.5% | Added |
| Total Clarity Wealth Management, Inc. | 1,820 | $536.4K | 0.13% | +1,820 | New |
| StoneX Group Inc. | 1,766 | $520.5K | 0.02% | +1,766 | New |
| Xponance, Inc. | 1,764 | $519.9K | 0.00% | +1,764 | New |
| Allspring Global Investments Holdings, LLC | 1,732 | $496.0K | 0.00% | +1,732 | New |
| ADAR1 Capital Management, LLC | 1,500 | $442.1K | 0.03% | +1,500 | New |
| CIBC World Markets Corp | 1,490 | $439.2K | 0.00% | +1,490 | New |
| Mackenzie Financial Corp | 1,399 | $414.7K | 0.00% | +1,399 | New |
| Persistent Asset Partners Ltd | 1,407 | $414.7K | 0.20% | +1,407 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,215 | $358.1K | 0.00% | +401+49.3% | Added |
| Mercer Global Advisors Inc | 1,212 | $357.2K | 0.00% | +1,212 | New |
| Sterling Capital Management LLC | 1,211 | $356.9K | 0.01% | +65+5.7% | Added |
| Kestra Advisory Services, LLC | 1,180 | $347.8K | 0.00% | +1,180 | New |
| Opal Capital LLC | 996 | $318.3K | 0.08% | +996 | New |
| Quest Partners LLC | 1,075 | $316.8K | 0.02% | −924−46.2% | Reduced |
| Martingale Asset Management L P | 1,056 | $311.2K | 0.01% | +1,056 | New |
| Abel Hall, LLC | 1,032 | $304.2K | 0.07% | +1,032 | New |
| Principal Financial Group Inc | 995 | $293.3K | 0.00% | +995 | New |
| Virtus Investment Advisers, Inc. | 989 | $291.5K | 0.08% | −1,538−60.9% | Reduced |
| Carl P. Sherr & Co., LLC | 897 | $281.7K | 0.13% | +897 | New |
| Swiss Life Asset Management Ltd | 946 | $278.8K | 0.00% | +946 | New |
| CIBC Asset Management Inc | 900 | $265.3K | 0.00% | −387,859−99.8% | Reduced |
| EntryPoint Capital, LLC | 887 | $261.4K | 0.10% | +887 | New |
| M&T Bank Corp | 885 | $261.0K | 0.00% | +885 | New |
| CWM, LLC | 874 | $258.0K | 0.00% | +117+15.5% | Added |
| Inscription Capital, LLC | 866 | $255.2K | 0.03% | +866 | New |
| MML Investors Services, LLC | 864 | $254.7K | 0.00% | +864 | New |
| HSBC Holdings PLC | 825 | $244.4K | 0.00% | −10,347−92.6% | Reduced |
| Ieq Capital, LLC | 815 | $240.2K | 0.00% | +815 | New |
| Amundi | 790 | $232.8K | 0.00% | +790 | New |
| O'Shaughnessy Asset Management, LLC | 768 | $226.4K | 0.00% | +768 | New |
| Commonwealth Equity Services, LLC | 745 | $219.6K | 0.00% | +745 | New |
| The PNC Financial Services Group, Inc. | 714 | $210.4K | 0.00% | +690+2,875.0% | Added |