Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 250
- +100 vs. Q3 2025
- Shares held
- 29.5M
- +4.80M (+19.5%) vs. Q3 2025
- Total value
- $8.69B
- +$7.38B (+564.4%) vs. Q3 2025
- New holders
- 115
- 87 more added
- Sold out
- 15
- 44 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SJS Investment Consulting Inc. | 1 | $295 | 0.00% | +1 | New |
| Keating Financial Advisory Services, Inc. | 1 | $295 | 0.00% | +1 | New |
| Marquette Asset Management, LLC | 2 | $590 | 0.00% | +2 | New |
| Covestor Ltd | 2 | $1.00K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 4 | $1.18K | 0.00% | +3+300.0% | Added |
| MAI Capital Management | 4 | $1.18K | 0.00% | +4 | New |
| Parallel Advisors, LLC | 4 | $1.18K | 0.00% | +4 | New |
| Bell Investment Advisors, Inc | 5 | $1.47K | 0.00% | +5 | New |
| MidFirst Bank | 5 | $1.47K | 0.00% | +5 | New |
| IFP Advisors, Inc | 6 | $1.77K | 0.00% | +3+100.0% | Added |
| Bellevue Asset Management, LLC | 6 | $1.77K | 0.00% | +6 | New |
| Bare Financial Services, Inc | 9 | $2.65K | 0.00% | +9 | New |
| ORG Partners LLC | 14 | $4.13K | 0.00% | +14 | New |
| Parkside Financial Bank & Trust | 14 | $4.13K | 0.00% | +4+40.0% | Added |
| Basecamp Wealth Advisors LLC | 16 | $4.72K | 0.00% | +16 | New |
| CIBC Private Wealth Group, LLC | 17 | $5.01K | 0.00% | +17 | New |
| Comerica Bank | 17 | $5.19K | 0.00% | +17 | New |
| J.Safra Asset Management Corp | 18 | $5.30K | 0.00% | +18 | New |
| EverSource Wealth Advisors, LLC | 25 | $7.37K | 0.00% | +7+38.9% | Added |
| Allworth Financial LP | 28 | $8.25K | 0.00% | +16+133.3% | Added |
| Federated Hermes, Inc. | 44 | $13.0K | 0.00% | +44 | New |
| Aspect Partners, LLC | 47 | $13.9K | 0.01% | +47 | New |
| Rothschild Investment LLC | 50 | $14.7K | 0.00% | +5+11.1% | Added |
| Accent Capital Management, LLC | 50 | $14.7K | 0.01% | +50 | New |
| Optiver Holding B.V. | 60 | $17.7K | 0.00% | −80−57.1% | Reduced |
| Kemnay Advisory Services Inc. | 61 | $18.0K | 0.00% | +61 | New |
| Rockefeller Capital Management L.P. | 64 | $18.9K | 0.00% | +62+3,100.0% | Added |
| SRS Capital Advisors, Inc. | 64 | $18.9K | 0.00% | −88−57.9% | Reduced |
| Activest Wealth Management | 68 | $20.0K | 0.00% | +68 | New |
| Daiwa Securities Group Inc. | 72 | $21.0K | 0.00% | +10+16.1% | Added |
| SBI Securities Co., Ltd. | 74 | $21.8K | 0.00% | −9−10.8% | Reduced |
| Havemeyer Place LP | 74 | $21.8K | 0.00% | +74 | New |
| Smartleaf Asset Management LLC | 74 | $22.0K | 0.00% | +74 | New |
| Advisor Group Holdings, Inc. | 83 | $24.5K | 0.00% | +3+3.8% | Added |
| Larson Financial Group LLC | 90 | $26.5K | 0.00% | +19+26.8% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 98 | $28.9K | 0.00% | 00.0% | Unchanged |
| NBC Securities, Inc. | 130 | $38.3K | 0.00% | +130 | New |
| Danske Bank A/S | 200 | $58.9K | 0.00% | +200 | New |
| GAMMA Investing LLC | 238 | $70.1K | 0.00% | +88+58.7% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 279 | $82.0K | 0.00% | +116+71.2% | Added |
| Farther Finance Advisors, LLC | 368 | $108.5K | 0.00% | +138+60.0% | Added |
| Los Angeles Capital Management LLC | 552 | $111.0K | 0.00% | +552 | New |
| GF Fund Management Co. Ltd. | 490 | $144.4K | 0.00% | +37+8.2% | Added |
| Global Retirement Partners, LLC | 600 | $176.8K | 0.00% | +600 | New |
| Tower Research Capital LLC (TRC) | 611 | $180.1K | 0.00% | −1,516−71.3% | Reduced |
| Acadian Asset Management LLC | 629 | $184.0K | 0.00% | +629 | New |
| KBC Group NV | 676 | $199.0K | 0.00% | +676 | New |
| Sanctuary Advisors, LLC | 681 | $200.7K | 0.00% | +681 | New |
| ACT Capital Management, LLC | 700 | $206.3K | 0.17% | +700 | New |
| Amalgamated Bank | 708 | $209.0K | 0.00% | +109+18.2% | Added |
| The PNC Financial Services Group, Inc. | 714 | $210.4K | 0.00% | +690+2,875.0% | Added |
| Commonwealth Equity Services, LLC | 745 | $219.6K | 0.00% | +745 | New |
| O'Shaughnessy Asset Management, LLC | 768 | $226.4K | 0.00% | +768 | New |
| Amundi | 790 | $232.8K | 0.00% | +790 | New |
| Ieq Capital, LLC | 815 | $240.2K | 0.00% | +815 | New |
| HSBC Holdings PLC | 825 | $244.4K | 0.00% | −10,347−92.6% | Reduced |
| MML Investors Services, LLC | 864 | $254.7K | 0.00% | +864 | New |
| Inscription Capital, LLC | 866 | $255.2K | 0.03% | +866 | New |
| CWM, LLC | 874 | $258.0K | 0.00% | +117+15.5% | Added |
| M&T Bank Corp | 885 | $261.0K | 0.00% | +885 | New |
| EntryPoint Capital, LLC | 887 | $261.4K | 0.10% | +887 | New |
| CIBC Asset Management Inc | 900 | $265.3K | 0.00% | −387,859−99.8% | Reduced |
| Swiss Life Asset Management Ltd | 946 | $278.8K | 0.00% | +946 | New |
| Carl P. Sherr & Co., LLC | 897 | $281.7K | 0.13% | +897 | New |
| Virtus Investment Advisers, Inc. | 989 | $291.5K | 0.08% | −1,538−60.9% | Reduced |
| Principal Financial Group Inc | 995 | $293.3K | 0.00% | +995 | New |
| Abel Hall, LLC | 1,032 | $304.2K | 0.07% | +1,032 | New |
| Martingale Asset Management L P | 1,056 | $311.2K | 0.01% | +1,056 | New |
| Quest Partners LLC | 1,075 | $316.8K | 0.02% | −924−46.2% | Reduced |
| Opal Capital LLC | 996 | $318.3K | 0.08% | +996 | New |
| Kestra Advisory Services, LLC | 1,180 | $347.8K | 0.00% | +1,180 | New |
| Sterling Capital Management LLC | 1,211 | $356.9K | 0.01% | +65+5.7% | Added |
| Mercer Global Advisors Inc | 1,212 | $357.2K | 0.00% | +1,212 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,215 | $358.1K | 0.00% | +401+49.3% | Added |
| Persistent Asset Partners Ltd | 1,407 | $414.7K | 0.20% | +1,407 | New |
| Mackenzie Financial Corp | 1,399 | $414.7K | 0.00% | +1,399 | New |
| CIBC World Markets Corp | 1,490 | $439.2K | 0.00% | +1,490 | New |
| ADAR1 Capital Management, LLC | 1,500 | $442.1K | 0.03% | +1,500 | New |
| Allspring Global Investments Holdings, LLC | 1,732 | $496.0K | 0.00% | +1,732 | New |
| Xponance, Inc. | 1,764 | $519.9K | 0.00% | +1,764 | New |
| StoneX Group Inc. | 1,766 | $520.5K | 0.02% | +1,766 | New |
| Total Clarity Wealth Management, Inc. | 1,820 | $536.4K | 0.13% | +1,820 | New |
| US Bancorp | 1,825 | $537.9K | 0.00% | +1,713+1,529.5% | Added |
| Y-Intercept (Hong Kong) Ltd | 1,856 | $547.0K | 0.01% | −30,330−94.2% | Reduced |
| Ameritas Investment Partners, Inc. | 1,866 | $550.0K | 0.02% | +347+22.8% | Added |
| Squarepoint Ops LLC | 1,890 | $557.1K | 0.00% | +1,890 | New |
| PSP Research LLC | 1,982 | $584.2K | 0.51% | +1,982 | New |
| Brinker Capital Investments, LLC | 1,985 | $585.1K | 0.00% | +1,985 | New |
| Quinn Opportunity Partners LLC | 2,000 | $589.5K | 0.03% | +2,000 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 2,082 | $613.6K | 0.09% | +2,082 | New |
| Ethic Inc. | 2,193 | $646.4K | 0.01% | +2,193 | New |
| Skopos Labs, Inc. | 2,179 | $663.7K | 0.03% | +2,179 | New |
| Susquehanna International Group, LLP | 2,343 | $690.6K | 0.00% | −26,994−92.0% | Reduced |
| Public Employees Retirement Association of Colorado | 2,390 | $704.0K | 0.00% | +2,173+1,001.4% | Added |
| Allianz Asset Management GmbH | 2,400 | $707.4K | 0.00% | +2,400 | New |
| Artia Global Partners LP | 2,500 | $736.9K | 0.12% | +2,500 | New |
| Seven Fleet Capital Management LP | 2,700 | $795.8K | 0.54% | +2,700 | New |
| Quantinno Capital Management LP | 2,723 | $802.6K | 0.00% | +2,723 | New |
| Teacher Retirement System of Texas | 3,053 | $899.8K | 0.00% | −1,416−31.7% | Reduced |
| STRS Ohio | 3,200 | $943.2K | 0.00% | +3,200 | New |