Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 152
- +9 vs. Q2 2025
- Shares held
- 24.7M
- +519.5K (+2.2%) vs. Q2 2025
- Total value
- $1.31B
- +$291.9M (+28.8%) vs. Q2 2025
- New holders
- 27
- 60 more added
- Sold out
- 18
- 45 more reduced
1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rafferty Asset Management, LLC | 37,573 | $1.99M | 0.01% | +12,768+51.5% | Added |
| Nuveen, LLC | 38,549 | $2.04M | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 39,660 | $2.10M | 0.05% | −78,461−66.4% | Reduced |
| TD Asset Management Inc | 40,884 | $2.17M | 0.00% | −23,054−36.1% | Reduced |
| FMR LLC | 43,211 | $2.29M | 0.00% | +5,111+13.4% | Added |
| Acuta Capital Partners, LLC | 49,751 | $2.64M | 2.72% | −24,336−32.8% | Reduced |
| Silverarc Capital Management, LLC | 51,210 | $2.71M | 0.39% | +41,210+412.1% | Added |
| Bank of New York Mellon Corp | 56,288 | $2.98M | 0.00% | +3,735+7.1% | Added |
| Qube Research & Technologies Ltd | 57,304 | $3.04M | 0.00% | +57,304 | New |
| Sphera Funds Management Ltd. | 57,901 | $3.07M | 0.73% | −51,856−47.2% | Reduced |
| PFM Health Sciences, LP | 60,578 | $3.21M | 0.27% | −24,135−28.5% | Reduced |
| Wellington Management Group LLP | 61,241 | $3.25M | 0.00% | +5,360+9.6% | Added |
| Candriam Luxembourg S.C.A. | 62,866 | $3.33M | 0.02% | −805−1.3% | Reduced |
| 72 Investment Holdings, LLC | 65,933 | $3.49M | 5.14% | 00.0% | Unchanged |
| Marshall Wace, LLP | 68,141 | $3.61M | 0.00% | +68,141 | New |
| Tri Locum Partners LP | 75,986 | $4.03M | 0.93% | −119,446−61.1% | Reduced |
| Kennedy Capital Management, Inc. | 76,218 | $4.04M | 0.09% | +5,773+8.2% | Added |
| Barclays PLC | 76,637 | $4.06M | 0.00% | −12,087−13.6% | Reduced |
| HighVista Strategies LLC | 95,002 | $5.04M | 1.23% | +27,714+41.2% | Added |
| UBS Group AG | 96,812 | $5.13M | 0.00% | +10,278+11.9% | Added |
| Exome Asset Management LLC | 101,996 | $5.41M | 3.57% | +42,994+72.9% | Added |
| Readystate Asset Management LP | 109,177 | $5.79M | 0.28% | +109,177 | New |
| Logos Global Management LP | 125,000 | $6.63M | 0.65% | −100,000−44.4% | Reduced |
| Velan Capital Investment Management LP | 132,805 | $7.04M | 6.61% | −16,529−11.1% | Reduced |
| Alyeska Investment Group, L.P. | 141,516 | $7.50M | 0.02% | +16,516+13.2% | Added |
| Algert Global LLC | 160,818 | $8.52M | 0.14% | +133,248+483.3% | Added |
| Charles Schwab Investment Management Inc | 161,661 | $8.57M | 0.00% | +9,217+6.0% | Added |
| Northern Trust Corp | 168,353 | $8.92M | 0.00% | −45,359−21.2% | Reduced |
| 5AM Venture Management, LLC | 170,000 | $9.01M | 3.30% | 00.0% | Unchanged |
| Sofinnova Investments, Inc. | 172,833 | $9.16M | 0.56% | +157,116+999.7% | Added |
| Vivo Capital, LLC | 198,895 | $10.5M | 0.85% | +31,295+18.7% | Added |
| Franklin Resources Inc | 314,157 | $16.7M | 0.00% | +70.0% | Added |
| CIBC Asset Management Inc | 388,759 | $20.6M | 0.06% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 409,779 | $21.7M | 0.03% | −194,519−32.2% | Reduced |
| Woodline Partners LP | 417,669 | $22.1M | 0.10% | +371,717+808.9% | Added |
| Geode Capital Management, LLC | 457,032 | $24.2M | 0.00% | +5,301+1.2% | Added |
| Bank of America Corp | 482,861 | $25.6M | 0.00% | +29,458+6.5% | Added |
| Driehaus Capital Management LLC | 500,551 | $26.5M | 0.19% | −30,437−5.7% | Reduced |
| Goldman Sachs Group Inc | 593,021 | $31.4M | 0.00% | +367,029+162.4% | Added |
| Morgan Stanley | 643,495 | $34.1M | 0.00% | −582,844−47.5% | Reduced |
| Baker Bros. Advisors LP | 689,488 | $36.5M | 0.26% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 840,851 | $44.6M | 0.68% | +153,920+22.4% | Added |
| Soleus Capital Management, L.P. | 859,166 | $45.5M | 2.43% | −107,574−11.1% | Reduced |
| State Street Corp | 907,108 | $48.1M | 0.00% | +209,015+29.9% | Added |
| Cormorant Asset Management, LP | 1,000,000 | $53.0M | 3.66% | −625,000−38.5% | Reduced |
| Price T Rowe Associates Inc | 1,003,490 | $53.2M | 0.01% | −469,585−31.9% | Reduced |
| Vanguard Group Inc | 1,267,286 | $67.2M | 0.00% | +51,642+4.2% | Added |
| Point72 Asset Management, L.P. | 1,495,986 | $79.3M | 0.17% | +541,911+56.8% | Added |
| Perceptive Advisors LLC | 1,564,554 | $82.9M | 2.40% | +811,633+107.8% | Added |
| BlackRock, Inc. | 1,801,080 | $95.5M | 0.00% | +210,952+13.3% | Added |
| Adage Capital Partners GP, L.L.C. | 2,374,085 | $125.8M | 0.20% | +399,500+20.2% | Added |
| Janus Henderson Group PLC | 2,763,859 | $146.5M | 0.07% | +230,454+9.1% | Added |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −369,254−100.0% | Sold out |
| Standard Life Aberdeen plc | 0 | $0 | 0.00% | −214,056−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −118,482−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −100,702−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −80,880−100.0% | Sold out |
| Pictet Asset Management Holding SA | 0 | $0 | 0.00% | −79,143−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −32,255−100.0% | Sold out |
| Capital Fund Management S.A. | 0 | $0 | 0.00% | −24,292−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −21,892−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −8,503−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −5,058−100.0% | Sold out |
| Maven Securities LTD | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −4,919−100.0% | Sold out |
| Toronto Dominion Bank | 0 | $0 | 0.00% | −3,100−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −298−100.0% | Sold out |
| Caitong International Asset Management Co., Ltd | 0 | $0 | 0.00% | −219−100.0% | Sold out |
| Twin Peaks Wealth Advisors, LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Norges Bank | – | – | – | – | Not filed |