Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Praxis Precision Medicines, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 150
- −11 vs. Q4 2024
- Shares held
- 23.5M
- +2.04M (+9.5%) vs. Q4 2024
- Total value
- $889.3M
- −$758.8M (−46.0%) vs. Q4 2024
- New holders
- 34
- 47 more added
- Sold out
- 45
- 52 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Candriam Luxembourg S.C.A. | 63,671 | $2.41M | 0.02% | −54,299−46.0% | Reduced |
| Kennedy Capital Management, Inc. | 65,265 | $2.47M | 0.06% | +65,265 | New |
| 72 Investment Holdings, LLC | 65,933 | $2.50M | 7.02% | 00.0% | Unchanged |
| Millennium Management LLC | 69,181 | $2.62M | 0.00% | −81,711−54.2% | Reduced |
| First Turn Management, LLC | 71,775 | $2.72M | 0.55% | +26,239+57.6% | Added |
| Pictet Asset Management Holding SA | 78,588 | $2.98M | 0.00% | +33,161+73.0% | Added |
| Tri Locum Partners LP | 83,659 | $3.17M | 1.63% | +46,390+124.5% | Added |
| Norges Bank | 84,200 | $3.19M | 0.00% | −34,700−29.2% | Reduced |
| UBS Asset Management Americas Inc | 87,081 | $3.30M | 0.00% | +68,466+367.8% | Added |
| Acuta Capital Partners, LLC | 87,141 | $3.30M | 3.83% | +19,641+29.1% | Added |
| Standard Life Aberdeen plc | 87,903 | $3.33M | 0.01% | +82,904+1,658.4% | Added |
| Ally Bridge Group (NY) LLC | 95,582 | $3.62M | 3.26% | +50,600+112.5% | Added |
| Sio Capital Management, LLC | 112,500 | $4.26M | 1.29% | +112,500 | New |
| Walleye Capital LLC | 131,756 | $4.99M | 0.06% | +42,143+47.0% | Added |
| Sphera Funds Management Ltd. | 140,660 | $5.33M | 1.31% | +49,077+53.6% | Added |
| Charles Schwab Investment Management Inc | 141,080 | $5.34M | 0.00% | −1,812−1.3% | Reduced |
| Ikarian Capital, LLC | 145,502 | $5.51M | 1.80% | +145,502 | New |
| Alyeska Investment Group, L.P. | 150,000 | $5.68M | 0.02% | −76,788−33.9% | Reduced |
| Sofinnova Investments, Inc. | 157,640 | $5.97M | 0.45% | +157,640 | New |
| PFM Health Sciences, LP | 160,866 | $6.09M | 0.47% | +41,357+34.6% | Added |
| Northern Trust Corp | 165,183 | $6.26M | 0.00% | −2,407−1.4% | Reduced |
| Silverarc Capital Management, LLC | 166,074 | $6.29M | 1.31% | +93,558+129.0% | Added |
| 5AM Venture Management, LLC | 170,000 | $6.44M | 2.43% | 00.0% | Unchanged |
| Woodline Partners LP | 175,727 | $6.65M | 0.04% | +165,779+1,666.5% | Added |
| Goldman Sachs Group Inc | 177,264 | $6.71M | 0.00% | −102,131−36.6% | Reduced |
| Velan Capital Investment Management LP | 185,000 | $7.01M | 7.21% | −115,000−38.3% | Reduced |
| UBS Group AG | 192,909 | $7.31M | 0.00% | +72,642+60.4% | Added |
| Verition Fund Management LLC | 199,657 | $7.56M | 0.04% | −264,851−57.0% | Reduced |
| Franklin Resources Inc | 314,127 | $11.9M | 0.00% | −75,708−19.4% | Reduced |
| Baker Bros. Advisors LP | 331,533 | $12.6M | 0.14% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 333,534 | $12.6M | 0.04% | −187,739−36.0% | Reduced |
| CIBC Asset Management Inc | 388,759 | $14.7M | 0.05% | +22,003+6.0% | Added |
| Balyasny Asset Management LLC | 403,003 | $15.3M | 0.04% | +403,003 | New |
| Geode Capital Management, LLC | 418,016 | $15.8M | 0.00% | +11,305+2.8% | Added |
| Bank of America Corp | 460,707 | $17.4M | 0.00% | +455,203+8,270.4% | Added |
| Driehaus Capital Management LLC | 481,598 | $18.2M | 0.18% | +316,686+192.0% | Added |
| Assenagon Asset Management S.A. | 507,400 | $19.2M | 0.03% | −51,682−9.2% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 619,931 | $23.5M | 0.47% | +619,931 | New |
| State Street Corp | 737,039 | $27.9M | 0.00% | −31,616−4.1% | Reduced |
| Capital Research Global Investors | 853,746 | $32.3M | 0.01% | −139,823−14.1% | Reduced |
| Perceptive Advisors LLC | 980,894 | $37.1M | 1.32% | −348,841−26.2% | Reduced |
| VR Adviser, LLC | 989,985 | $37.5M | 3.19% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,087,020 | $41.2M | 0.00% | +23,381+2.2% | Added |
| Price T Rowe Associates Inc | 1,095,725 | $41.5M | 0.01% | −112,797−9.3% | Reduced |
| Soleus Capital Management, L.P. | 1,139,740 | $43.2M | 3.38% | +896,200+368.0% | Added |
| Morgan Stanley | 1,213,669 | $46.0M | 0.00% | +50,143+4.3% | Added |
| BlackRock, Inc. | 1,416,935 | $53.7M | 0.00% | −45,510−3.1% | Reduced |
| Janus Henderson Group PLC | 1,506,436 | $58.3M | 0.03% | +576,913+62.1% | Added |
| Adage Capital Partners GP, L.L.C. | 1,742,758 | $66.0M | 0.12% | +1,137,748+188.1% | Added |
| Cormorant Asset Management, LP | 1,745,000 | $66.1M | 5.00% | +51,781+3.1% | Added |
| Bessemer Group Inc | 0 | $0 | 0.00% | −25−100.0% | Sold out |
| Ra Capital Management, L.P. | 0 | $0 | 0.00% | −761,955−100.0% | Sold out |
| Kingdon Capital Management, L.L.C. | 0 | $0 | 0.00% | −303,000−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −134,178−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −116,062−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −98,617−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −58,305−100.0% | Sold out |
| Simplify Asset Management Inc. | 0 | $0 | 0.00% | −43,085−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −31,999−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −27,650−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −15,594−100.0% | Sold out |
| J. Goldman & Co LP | 0 | $0 | 0.00% | −11,634−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −11,188−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −9,496−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −9,115−100.0% | Sold out |
| Nicholas Investment Partners, LP | 0 | $0 | 0.00% | −8,481−100.0% | Sold out |
| Ellsworth Advisors, LLC | 0 | $0 | 0.00% | −8,150−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −7,782−100.0% | Sold out |
| AQR Capital Management LLC | 0 | $0 | 0.00% | −6,704−100.0% | Sold out |
| ProShare Advisors LLC | 0 | $0 | 0.00% | −5,738−100.0% | Sold out |
| Voya Investment Management LLC | 0 | $0 | 0.00% | −5,228−100.0% | Sold out |
| Maven Securities LTD | 0 | $0 | 0.00% | −5,000−100.0% | Sold out |
| SEI Investments Co | 0 | $0 | 0.00% | −4,918−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −4,544−100.0% | Sold out |
| Cerity Partners LLC | 0 | $0 | 0.00% | −4,364−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −4,102−100.0% | Sold out |
| Mesirow Financial Investment Management, Inc. | 0 | $0 | 0.00% | −4,047−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −3,961−100.0% | Sold out |
| Arizona State Retirement System | 0 | $0 | 0.00% | −3,851−100.0% | Sold out |
| Coastal Bridge Advisors, LLC | 0 | $0 | 0.00% | −3,846−100.0% | Sold out |
| Glenmede Trust Co NA | 0 | $0 | 0.00% | −3,809−100.0% | Sold out |
| Pale Fire Capital SE | 0 | $0 | 0.00% | −3,369−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −3,195−100.0% | Sold out |
| Freestone Grove Partners LP | 0 | $0 | 0.00% | −3,080−100.0% | Sold out |
| Envestnet Asset Management Inc | 0 | $0 | 0.00% | −3,008−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −2,832−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −1,001−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −156−100.0% | Sold out |
| Creative Planning | 0 | $0 | 0.00% | −106−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −90−100.0% | Sold out |
| True Wealth Design, LLC | 0 | $0 | 0.00% | −25−100.0% | Sold out |
| Lindbrook Capital, LLC | 0 | $0 | 0.00% | −11−100.0% | Sold out |
| Assetmark, Inc | 0 | $0 | 0.00% | −7−100.0% | Sold out |
| Parallel Advisors, LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Capital Advisors, Ltd. LLC | 0 | $0 | 0.00% | −2−100.0% | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |