Praxis Precision Medicines, Inc.
PRAX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001689548
No open-market purchases or sales by Praxis Precision Medicines, Inc. insiders were filed in the last 90 days; 309 institutions reported holding it in 13F filings for Q2 2026, worth $11.3B in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Praxis Precision Medicines, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 162
- +28 vs. Q3 2024
- Shares held
- 21.7M
- +2.85M (+15.1%) vs. Q3 2024
- Total value
- $1.67B
- +$580.5M (+53.2%) vs. Q3 2024
- New holders
- 38
- 56 more added
- Sold out
- 10
- 52 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PRAX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 309 | $11.3B |
| Q1 2026 | 291 | $10.2B |
| Q4 2025 | 250 | $8.69B |
| Q3 2025 | 152 | $1.31B |
| Q2 2025 | 144 | $1.02B |
| Q1 2025 | 150 | $889.3M |
| Q4 2024 | 162 | $1.67B |
| Q3 2024 | 134 | $1.09B |
| Q2 2024 | 113 | $762.1M |
| Q1 2024 | 111 | $971.3M |
| Q4 2023 | 60 | $178.6M |
| Q3 2023 | 74 | $195.6M |
| Q2 2023 | 78 | $134.6M |
| Q1 2023 | 87 | $43.1M |
| Q4 2022 | 104 | $108.1M |
| Q3 2022 | 108 | $95.7M |
| Q2 2022 | 95 | $105.5M |
| Q1 2022 | 103 | $463.4M |
| Q4 2021 | 100 | $863.1M |
| Q3 2021 | 93 | $791.5M |
| Q2 2021 | 80 | $751.0M |
| Q1 2021 | 68 | $1.19B |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Praxis Precision Medicines, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Tri Locum Partners LP | 37,269 | $2.87M | 0.59% | +37,269 | New |
| Barclays PLC | 37,288 | $2.87M | 0.00% | +158+0.4% | Added |
| Manufacturers Life Insurance Company, The | 38,483 | $2.96M | 0.00% | +3,344+9.5% | Added |
| Jacobs Levy Equity Management, Inc | 39,999 | $3.08M | 0.01% | 00.0% | Unchanged |
| Simplify Asset Management Inc. | 43,085 | $3.32M | 0.23% | +43,085 | New |
| Schonfeld Strategic Advisors LLC | 43,100 | $3.32M | 0.02% | +14,649+51.5% | Added |
| Ally Bridge Group (NY) LLC | 44,982 | $3.46M | 2.97% | −28,203−38.5% | Reduced |
| Pictet Asset Management Holding SA | 45,427 | $3.50M | 0.00% | +45,427 | New |
| First Turn Management, LLC | 45,536 | $3.50M | 0.63% | +45,536 | New |
| Bank of New York Mellon Corp | 46,856 | $3.61M | 0.00% | −1,351−2.8% | Reduced |
| D. E. Shaw & Co., Inc. | 47,993 | $3.69M | 0.00% | +1,629+3.5% | Added |
| TD Asset Management Inc | 52,898 | $4.07M | 0.00% | +9,000+20.5% | Added |
| Marshall Wace, LLP | 58,305 | $4.49M | 0.01% | −111,790−65.7% | Reduced |
| Wellington Management Group LLP | 63,934 | $4.92M | 0.00% | −155,973−70.9% | Reduced |
| 72 Investment Holdings, LLC | 65,933 | $5.07M | 10.33% | 00.0% | Unchanged |
| Acuta Capital Partners, LLC | 67,500 | $5.19M | 5.23% | +10,000+17.4% | Added |
| Silverarc Capital Management, LLC | 72,516 | $5.58M | 1.25% | +5,471+8.2% | Added |
| Alliancebernstein L.P. | 78,627 | $6.05M | 0.00% | +60,587+335.8% | Added |
| Invesco Ltd. | 86,983 | $6.69M | 0.00% | −20,730−19.2% | Reduced |
| Walleye Capital LLC | 89,613 | $6.90M | 0.07% | +34,000+61.1% | Added |
| Sphera Funds Management Ltd. | 91,583 | $7.05M | 1.30% | −60,724−39.9% | Reduced |
| Citadel Advisors LLC | 93,190 | $7.17M | 0.01% | +45,156+94.0% | Added |
| Citigroup Inc | 95,047 | $7.31M | 0.01% | +11,697+14.0% | Added |
| Polar Asset Management Partners Inc. | 98,617 | $7.59M | 0.11% | +98,617 | New |
| Voloridge Investment Management, LLC | 116,062 | $8.93M | 0.03% | +40,875+54.4% | Added |
| Candriam Luxembourg S.C.A. | 117,970 | $9.08M | 0.05% | −44,061−27.2% | Reduced |
| Norges Bank | 118,900 | $9.15M | 0.00% | +113,900+2,278.0% | Added |
| PFM Health Sciences, LP | 119,509 | $9.20M | 0.70% | −63,583−34.7% | Reduced |
| UBS Group AG | 120,267 | $9.26M | 0.00% | +90,717+307.0% | Added |
| StemPoint Capital LP | 134,178 | $10.3M | 2.59% | −39,856−22.9% | Reduced |
| Charles Schwab Investment Management Inc | 142,892 | $11.0M | 0.00% | +5,840+4.3% | Added |
| Millennium Management LLC | 150,892 | $11.6M | 0.01% | +146,723+3,519.4% | Added |
| Susquehanna International Group, LLP | 157,925 | $12.2M | 0.02% | +128,931+444.7% | Added |
| Driehaus Capital Management LLC | 164,912 | $12.7M | 0.10% | −1,144−0.7% | Reduced |
| Northern Trust Corp | 167,590 | $12.9M | 0.00% | +15,323+10.1% | Added |
| 5AM Venture Management, LLC | 170,000 | $13.1M | 3.12% | −170,000−50.0% | Reduced |
| FMR LLC | 188,367 | $14.5M | 0.00% | −85,528−31.2% | Reduced |
| Alyeska Investment Group, L.P. | 226,788 | $17.5M | 0.07% | +226,788 | New |
| Soleus Capital Management, L.P. | 243,540 | $18.7M | 1.42% | −15,858−6.1% | Reduced |
| Goldman Sachs Group Inc | 279,395 | $21.5M | 0.00% | −225−0.1% | Reduced |
| Velan Capital Investment Management LP | 300,000 | $23.1M | 19.92% | −50,666−14.4% | Reduced |
| Kingdon Capital Management, L.L.C. | 303,000 | $23.3M | 3.99% | −65,000−17.7% | Reduced |
| Nuveen Asset Management, LLC | 306,911 | $23.6M | 0.01% | +2,084+0.7% | Added |
| Baker Bros. Advisors LP | 331,533 | $25.5M | 0.27% | +8,428+2.6% | Added |
| CIBC Asset Management Inc | 366,756 | $28.2M | 0.09% | +117,817+47.3% | Added |
| Franklin Resources Inc | 389,835 | $30.0M | 0.01% | −55,398−12.4% | Reduced |
| Geode Capital Management, LLC | 406,711 | $31.3M | 0.00% | +7,873+2.0% | Added |
| Verition Fund Management LLC | 464,508 | $35.7M | 0.18% | −94,643−16.9% | Reduced |
| Point72 Asset Management, L.P. | 521,273 | $40.1M | 0.11% | −511,971−49.5% | Reduced |
| Assenagon Asset Management S.A. | 559,082 | $43.0M | 0.08% | +548,986+5,437.7% | Added |
| Adage Capital Partners GP, L.L.C. | 605,010 | $46.6M | 0.08% | −249,073−29.2% | Reduced |
| Ra Capital Management, L.P. | 761,955 | $58.6M | 0.78% | 00.0% | Unchanged |
| State Street Corp | 768,655 | $59.2M | 0.00% | −20,969−2.7% | Reduced |
| Janus Henderson Group PLC | 929,523 | $71.6M | 0.04% | +405,957+77.5% | Added |
| VR Adviser, LLC | 989,985 | $76.2M | 5.23% | +283,854+40.2% | Added |
| Capital Research Global Investors | 993,569 | $76.5M | 0.02% | −3,525−0.4% | Reduced |
| Vanguard Group Inc | 1,063,639 | $81.9M | 0.00% | +24,645+2.4% | Added |
| Morgan Stanley | 1,163,526 | $89.5M | 0.01% | +1,083,026+1,345.4% | Added |
| Price T Rowe Associates Inc | 1,208,522 | $93.0M | 0.01% | +88,442+7.9% | Added |
| Perceptive Advisors LLC | 1,329,735 | $102.3M | 2.85% | +165,700+14.2% | Added |
| BlackRock, Inc. | 1,462,445 | $112.5M | 0.00% | +160,010+12.3% | Added |
| Cormorant Asset Management, LP | 1,693,219 | $130.3M | 7.16% | +823,219+94.6% | Added |
| Octagon Capital Advisors LP | 0 | $0 | 0.00% | −130,000−100.0% | Sold out |
| Group One Trading, L.P. | 0 | $0 | 0.00% | −60,818−100.0% | Sold out |
| Ovata Capital Management Ltd | 0 | $0 | 0.00% | −9,777−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −9,204−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −5,158−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −1,189−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −71−100.0% | Sold out |
| Capital Performance Advisors LLP | 0 | $0 | 0.00% | −22−100.0% | Sold out |
| Global Retirement Partners, LLC | 0 | $0 | 0.00% | −14−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −1−100.0% | Sold out |