Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Opko Health, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 233
- +16 vs. Q2 2025
- Shares held
- 196.3M
- −8.63M (−4.2%) vs. Q2 2025
- Total value
- $303.6M
- +$33.5M (+12.4%) vs. Q2 2025
- New holders
- 30
- 77 more added
- Sold out
- 14
- 53 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Private Advisor Group, LLC | 55,301 | $85.7K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $85.5K | 0.00% | 00.0% | Unchanged |
| Prudential Financial Inc | 54,772 | $84.9K | 0.00% | +7,930+16.9% | Added |
| Transcend Wealth Collective, LLC | 52,565 | $81.5K | 0.01% | +1,714+3.4% | Added |
| First Manhattan Co | 51,750 | $80.2K | 0.00% | 00.0% | Unchanged |
| Great West Life Assurance Co | 54,068 | $79.0K | 0.00% | 00.0% | Unchanged |
| Farmers National Bank | 50,300 | $78.0K | 0.02% | 00.0% | Unchanged |
| Headlands Technologies LLC | 45,240 | $70.1K | 0.01% | −12,484−21.6% | Reduced |
| CIBC Bancorp USA Inc. | 43,868 | $68.0K | 0.00% | +43,868 | New |
| Squarepoint Ops LLC | 42,519 | $65.9K | 0.00% | −49,915−54.0% | Reduced |
| Atom Investors LP | 41,872 | $64.9K | 0.00% | −1,410−3.3% | Reduced |
| Victory Capital Management Inc | 41,304 | $64.0K | 0.00% | −457−1.1% | Reduced |
| RK Asset Management, LLC | 40,485 | $63.0K | 0.06% | 00.0% | Unchanged |
| Pensionmark Financial Group, LLC | 40,618 | $63.0K | 0.00% | 00.0% | Unchanged |
| HighTower Advisors, LLC | 40,407 | $62.6K | 0.00% | +1,501+3.9% | Added |
| State of Wisconsin Investment Board | 39,097 | $60.6K | 0.00% | +17,904+84.5% | Added |
| EntryPoint Capital, LLC | 38,828 | $60.2K | 0.02% | +38,828 | New |
| Kestra Advisory Services, LLC | 38,807 | $60.2K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 34,690 | $53.8K | 0.00% | +34,070+5,495.2% | Added |
| Cerity Partners LLC | 34,566 | $53.6K | 0.00% | +34,566 | New |
| RSM US Wealth Management LLC | 33,757 | $52.3K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 32,748 | $50.8K | 0.00% | −134,363−80.4% | Reduced |
| Xponance, Inc. | 32,170 | $49.9K | 0.00% | +4,221+15.1% | Added |
| Norris Perne & French LLP | 32,000 | $49.6K | 0.00% | 00.0% | Unchanged |
| Operose Advisors LLC | 32,000 | $49.6K | 0.01% | 00.0% | Unchanged |
| STRS Ohio | 31,900 | $49.4K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 31,889 | $49.4K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 30,935 | $47.9K | 0.00% | +10,699+52.9% | Added |
| Brinker Capital Investments, LLC | 30,096 | $46.6K | 0.00% | +96+0.3% | Added |
| Fisher Asset Management, LLC | 30,000 | $46.5K | 0.00% | −301−1.0% | Reduced |
| IPG Investment Advisors LLC | 30,000 | $46.5K | 0.01% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 29,928 | $46.4K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 28,737 | $44.5K | 0.00% | +3,964+16.0% | Added |
| Sterling Capital Management LLC | 28,396 | $44.0K | 0.00% | +18,628+190.7% | Added |
| Diversify Wealth Management, LLC | 30,000 | $42.0K | 0.00% | 00.0% | Unchanged |
| PBMares Wealth Management LLC | 27,021 | $41.9K | 0.01% | 00.0% | Unchanged |
| Mackenzie Financial Corp | 25,843 | $40.1K | 0.00% | 00.0% | Unchanged |
| SlateStone Wealth, LLC | 25,770 | $40.0K | 0.00% | 00.0% | Unchanged |
| Cim Investment Mangement Inc | 25,804 | $40.0K | 0.01% | −27,787−51.9% | Reduced |
| Moseley Investment Management Inc | 25,153 | $39.0K | 0.01% | +1,000+4.1% | Added |
| Arrow Financial Corp | 25,000 | $38.8K | 0.00% | +25,000 | New |
| Capital Advisors Inc | 370,000 | $36.6K | 0.00% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 21,918 | $34.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 21,543 | $33.4K | 0.00% | −9,170−29.9% | Reduced |
| X-Square Capital, LLC | 20,933 | $32.0K | 0.01% | −107−0.5% | Reduced |
| Sax Wealth Advisors, LLC | 20,380 | $31.6K | 0.00% | +220+1.1% | Added |
| Sovereign Financial Group, Inc. | 20,078 | $31.1K | 0.01% | 00.0% | Unchanged |
| Cumberland Advisors Inc | 19,500 | $30.2K | 0.01% | 00.0% | Unchanged |
| Swiss Life Asset Management Ltd | 19,164 | $29.7K | 0.00% | +19,164 | New |
| Shufro Rose & Co LLC | 17,000 | $28.2K | 0.00% | 00.0% | Unchanged |
| Integrated Wealth Concepts LLC | 17,698 | $27.4K | 0.00% | +3,376+23.6% | Added |
| Equitable Holdings, Inc. | 17,056 | $26.4K | 0.00% | −11,875−41.0% | Reduced |
| Stifel Financial Corp | 16,858 | $26.1K | 0.00% | +169+1.0% | Added |
| Shell Asset Management Co | 16,596 | $26.0K | 0.00% | −20,432−55.2% | Reduced |
| Buckingham Strategic Partners | 18,031 | $25.8K | 0.00% | +18,031 | New |
| FMR LLC | 16,564 | $25.7K | 0.00% | +443+2.7% | Added |
| Westmount Partners, LLC | 16,550 | $25.7K | 0.01% | 00.0% | Unchanged |
| Commons Capital, LLC | 16,300 | $25.3K | 0.02% | 00.0% | Unchanged |
| Sigma Planning Corp | 15,807 | $24.5K | 0.00% | −2,165−12.0% | Reduced |
| Colony Group, LLC | 15,675 | $24.3K | 0.00% | +15,675 | New |
| Sanctuary Advisors, LLC | 15,667 | $24.3K | 0.00% | +1,627+11.6% | Added |
| Kovack Advisors, Inc. | 15,000 | $23.3K | 0.00% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 16,770 | $23.1K | 0.00% | +16,770 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,823 | $23.0K | 0.00% | +14,823 | New |
| Colony Family Offices, LLC | 14,729 | $22.8K | 0.01% | 00.0% | Unchanged |
| MML Investors Services, LLC | 14,026 | $21.7K | 0.00% | +14,026 | New |
| Merit Financial Group, LLC | 13,585 | $21.1K | 0.00% | +13,585 | New |
| HBK Sorce Advisory LLC | 13,527 | $20.6K | 0.00% | +2,470+22.3% | Added |
| Jones Financial Companies LLLP | 14,125 | $20.5K | 0.00% | +850+6.4% | Added |
| NorthCrest Asset Manangement, LLC | 12,470 | $19.2K | 0.00% | +12,470 | New |
| Mill Creek Capital Advisors, LLC | 12,383 | $19.2K | 0.00% | 00.0% | Unchanged |
| Formidable Asset Management, LLC | 14,296 | $18.9K | 0.00% | −750−5.0% | Reduced |
| Pallas Capital Advisors LLC | 11,710 | $18.2K | 0.00% | +11,710 | New |
| Traphagen Investment Advisors LLC | 11,680 | $18.1K | 0.00% | 00.0% | Unchanged |
| Point72 (DIFC) Ltd | 11,450 | $17.7K | 0.00% | +11,450 | New |
| Stillwater Capital Advisors, LLC | 11,380 | $17.6K | 0.00% | 00.0% | Unchanged |
| Key Financial Inc | 11,000 | $17.1K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 11,110 | $17.0K | 0.00% | 00.0% | Unchanged |
| Diversified Trust Co | 10,374 | $16.1K | 0.00% | +374+3.7% | Added |
| SEI Investments Co | 10,163 | $15.8K | 0.00% | 00.0% | Unchanged |
| Capital Square, LLC | 10,000 | $15.5K | 0.01% | −1,000−9.1% | Reduced |
| KLCM Advisors, Inc. | 10,000 | $15.5K | 0.00% | 00.0% | Unchanged |
| Simplicity Wealth,LLC | 10,000 | $15.5K | 0.00% | 00.0% | Unchanged |
| Greenbush Financial Group, LLC | 10,000 | $15.5K | 0.01% | 00.0% | Unchanged |
| Point72 Asia (Singapore) Pte. Ltd. | 9,624 | $14.9K | 0.00% | +9,624 | New |
| Krilogy Financial LLC | 10,910 | $14.6K | 0.00% | +10,910 | New |
| MRP Capital Investments, LLC | 10,000 | $13.2K | 0.01% | 00.0% | Unchanged |
| Aventura Private Wealth, LLC | 8,400 | $13.0K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 7,110 | $11.0K | 0.00% | −30−0.4% | Reduced |
| EverSource Wealth Advisors, LLC | 6,793 | $10.5K | 0.00% | +4,116+153.8% | Added |
| National Bank of Canada | 6,200 | $9.55K | 0.00% | +1,278+26.0% | Added |
| Allworth Financial LP | 5,985 | $9.28K | 0.00% | +4,172+230.1% | Added |
| Essential Partners LLC | 5,382 | $8.34K | 0.00% | +4,358+425.6% | Added |
| Aster Capital Management (DIFC) Ltd | 4,680 | $7.25K | 0.00% | +1,227+35.5% | Added |
| Nisa Investment Advisors, LLC | 4,472 | $6.93K | 0.00% | +169+3.9% | Added |
| FSA Wealth Management LLC | 3,950 | $6.12K | 0.00% | 00.0% | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 3,777 | $6.00K | 0.00% | 00.0% | Unchanged |
| Wealthspire Advisors, LLC | 3,700 | $5.74K | 0.00% | +3,700 | New |
| Caitong International Asset Management Co., Ltd | 3,391 | $5.26K | 0.00% | +3,391 | New |
| Gables Capital Management Inc. | 3,000 | $4.65K | 0.00% | 00.0% | Unchanged |