Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Opko Health, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 233
- +16 vs. Q2 2025
- Shares held
- 196.3M
- −8.63M (−4.2%) vs. Q2 2025
- Total value
- $303.6M
- +$33.5M (+12.4%) vs. Q2 2025
- New holders
- 30
- 77 more added
- Sold out
- 14
- 53 more reduced
5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Optiver Holding B.V. | 2,756 | $4.27K | 0.00% | +2,756 | New |
| Smartleaf Asset Management LLC | 2,757 | $4.05K | 0.00% | +2,283+481.6% | Added |
| CoreCap Advisors, LLC | 1,600 | $2.48K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 1,401 | $2.17K | 0.00% | +1,401 | New |
| PFS Partners, LLC | 1,100 | $1.71K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 1,100 | $1.71K | 0.00% | +500+83.3% | Added |
| Altshuler Shaham Ltd | 1,132 | $1.69K | 0.00% | −21,339−95.0% | Reduced |
| MAI Capital Management | 1,000 | $1.55K | 0.00% | 00.0% | Unchanged |
| Salomon & Ludwin, LLC | 951 | $1.48K | 0.00% | −25−2.6% | Reduced |
| True Wealth Design, LLC | 866 | $1.34K | 0.00% | +853+6,561.5% | Added |
| Rothschild Investment LLC | 679 | $1.05K | 0.00% | +279+69.8% | Added |
| IFP Advisors, Inc | 611 | $947 | 0.00% | +172+39.2% | Added |
| Parkside Financial Bank & Trust | 395 | $613 | 0.00% | +395 | New |
| Pittenger & Anderson Inc | 250 | $388 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 227 | $352 | 0.00% | 00.0% | Unchanged |
| Medallion Wealth Advisors, LLC | 200 | $310 | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 200 | $310 | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 187 | $290 | 0.00% | +187 | New |
| Harbor Investment Advisory, LLC | 180 | $279 | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 100 | $155 | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 100 | $155 | 0.00% | +100 | New |
| Boreal Capital Management LLC | 69 | $107 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 53 | $82 | 0.00% | −39−42.4% | Reduced |
| Larson Financial Group LLC | 40 | $62 | 0.00% | −3,000−98.7% | Reduced |
| Advisory Services Network, LLC | 23 | $36 | 0.00% | +23 | New |
| Darwin Advisors, LLC | 5 | $7 | 0.00% | 00.0% | Unchanged |
| Crewe Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| LRI Investments, LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| Guerra Advisors Inc | 1 | $2 | 0.00% | +1 | New |
| Farther Finance Advisors, LLC | 1 | $1 | 0.00% | −12,218−100.0% | Reduced |
| Centerpoint Advisors, LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 316 | $0 | 0.00% | +133+72.7% | Added |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −3,348,166−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −883,042−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −695,780−100.0% | Sold out |
| Intrepid Capital Management Inc | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −84,907−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −55,124−100.0% | Sold out |
| HSBC Holdings PLC | 0 | $0 | 0.00% | −34,939−100.0% | Sold out |
| Kapitalo Investimentos Ltda | 0 | $0 | 0.00% | −31,347−100.0% | Sold out |
| Janney Montgomery Scott LLC | 0 | $0 | 0.00% | −12,500−100.0% | Sold out |
| Raiffeisen Bank International AG | 0 | $0 | 0.00% | −6,521−100.0% | Sold out |
| Transce3nd, LLC | 0 | $0 | 0.00% | −900−100.0% | Sold out |
| CBIZ Investment Advisory Services, LLC | 0 | $0 | 0.00% | −698−100.0% | Sold out |
| UMA Financial Services, Inc. | 0 | $0 | 0.00% | −470−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −273−100.0% | Sold out |
| Teton Advisors, Inc. | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| Norges Bank | – | – | – | – | Not filed |
| EP Wealth Advisors, LLC | – | – | – | – | Not filed |
| Moser Wealth Advisors, LLC | – | – | – | – | Not filed |