Opko Health, Inc.

OPK

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0000944809

SEC filings (opens in a new tab)

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Opko Health, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025 All holders in Q2 2025

13F holders of OPK: Q2 2025 compared with Q3 2025
Measure	Q2 2025	Of which not filed for Q3 2025	Q3 2025	Change
Holders	222	5	233	+16
Shares	205.2M	257.3K	196.3M	−8.63M (−4.2%)
Value	$270.4M	$339.7K	$303.6M	+$33.5M (+12.4%)

5 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (30)

Institutions that held Opko Health, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to OPK in Q3 2025
Institution	Shares	Value	% of portfolio
Simplex Trading, LLC	150,566	$233.0K	0.01%
Teton Advisors, LLC	142,000	$220.1K	0.14%
Two Sigma Securities, LLC	121,094	$187.7K	0.03%
RPg Family Wealth Advisory, LLC	98,990	$153.4K	0.03%
SRS Capital Advisors, Inc.	63,780	$98.9K	0.00%
CIBC Bancorp USA Inc.	43,868	$68.0K	0.00%
EntryPoint Capital, LLC	38,828	$60.2K	0.02%
Cerity Partners LLC	34,566	$53.6K	0.00%
Arrow Financial Corp	25,000	$38.8K	0.00%
Swiss Life Asset Management Ltd	19,164	$29.7K	0.00%
Buckingham Strategic Partners	18,031	$25.8K	0.00%
Colony Group, LLC	15,675	$24.3K	0.00%
CAPROCK Group, Inc.	16,770	$23.1K	0.00%
Universal- Beteiligungs- und Servicegesellschaft mbH	14,823	$23.0K	0.00%
MML Investors Services, LLC	14,026	$21.7K	0.00%
Merit Financial Group, LLC	13,585	$21.1K	0.00%
NorthCrest Asset Manangement, LLC	12,470	$19.2K	0.00%
Pallas Capital Advisors LLC	11,710	$18.2K	0.00%
Point72 (DIFC) Ltd	11,450	$17.7K	0.00%
Point72 Asia (Singapore) Pte. Ltd.	9,624	$14.9K	0.00%
Krilogy Financial LLC	10,910	$14.6K	0.00%
Wealthspire Advisors, LLC	3,700	$5.74K	0.00%
Caitong International Asset Management Co., Ltd	3,391	$5.26K	0.00%
Optiver Holding B.V.	2,756	$4.27K	0.00%
Rockefeller Capital Management L.P.	1,401	$2.17K	0.00%
Parkside Financial Bank & Trust	395	$613	0.00%
Transamerica Financial Advisors, Inc.	187	$290	0.00%
Root Financial Partners, LLC	100	$155	0.00%
Advisory Services Network, LLC	23	$36	0.00%
Guerra Advisors Inc	1	$2	0.00%

Sold out (14)

Institutions that held Opko Health, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of OPK in Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Marshall Wace, LLP	3,348,166	$4.42M
Clearstead Advisors, LLC	883,042	$1.17M
Millennium Management LLC	695,780	$918.4K
Intrepid Capital Management Inc	100,000	$132.0K
XTX Topco Ltd	84,907	$112.1K
Engineers Gate Manager LP	55,124	$72.8K
HSBC Holdings PLC	34,939	$46.3K
Kapitalo Investimentos Ltda	31,347	$41.4K
Janney Montgomery Scott LLC	12,500	$16.0K
Raiffeisen Bank International AG	6,521	$8.61K
Transce3nd, LLC	900	$1.19K
CBIZ Investment Advisory Services, LLC	698	$921
UMA Financial Services, Inc.	470	$621
Bessemer Group Inc	273	$0

Not filed for Q3 2025 yet (5)

Institutions that held Opko Health, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding OPK in Q2 2025 that haven't filed for Q3 2025
Institution	Shares, Q2 2025	Value, Q2 2025
Teton Advisors, Inc.	142,000	$187.4K
CIBC World Markets Corp	44,575	$58.8K
Norges Bank	39,477	$52.1K
EP Wealth Advisors, LLC	28,900	$38.1K
Moser Wealth Advisors, LLC	2,392	$3.16K