Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q4 2024
Institutional positions in Lyra Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 54
- −7 vs. Q3 2024
- Shares held
- 26.9M
- −5.63M (−17.3%) vs. Q3 2024
- Total value
- $5.54M
- −$2.81M (−33.7%) vs. Q3 2024
- New holders
- 8
- 20 more added
- Sold out
- 15
- 11 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Simplex Trading, LLC | 363 | $0 | 0.00% | −3,794−91.3% | Reduced |
| Amalgamated Bank | 1,674 | $0 | 0.00% | 00.0% | Unchanged |
| Sterling Capital Management LLC | 88 | $18 | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 119 | $25 | 0.00% | +119 | New |
| Jones Financial Companies LLLP | 500 | $103 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 500 | $103 | 0.00% | +463+1,251.4% | Added |
| Bryn Mawr Trust Co | 1,025 | $212 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 1,159 | $239 | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 3,507 | $724 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 4,269 | $881 | 0.00% | +4,269 | New |
| Ameritas Investment Partners, Inc. | 4,741 | $979 | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 5,371 | $1.00K | 0.00% | +4,634+628.8% | Added |
| Royal Bank of Canada | 5,294 | $2.00K | 0.00% | −877−14.2% | Reduced |
| ProShare Advisors LLC | 13,631 | $2.81K | 0.00% | +13,631 | New |
| Abel Hall, LLC | 17,647 | $3.64K | 0.00% | +17,647 | New |
| Price T Rowe Associates Inc | 17,541 | $4.00K | 0.00% | 00.0% | Unchanged |
| Invesco Ltd. | 23,626 | $4.88K | 0.00% | +972+4.3% | Added |
| Corebridge Financial, Inc. | 24,061 | $4.97K | 0.00% | −1,816−7.0% | Reduced |
| Wells Fargo & Company | 24,744 | $5.11K | 0.00% | +7,148+40.6% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 27,770 | $5.73K | 0.00% | +1,216+4.6% | Added |
| AQR Capital Management LLC | 28,713 | $5.93K | 0.00% | −25,317−46.9% | Reduced |
| Alliancebernstein L.P. | 33,120 | $6.84K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 31,907 | $7.00K | 0.00% | −4,502−12.4% | Reduced |
| Citigroup Inc | 38,102 | $7.86K | 0.00% | +3,066+8.8% | Added |
| Tower Research Capital LLC (TRC) | 39,785 | $8.20K | 0.00% | +24,662+163.1% | Added |
| Rhumbline Advisers | 41,258 | $8.49K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 42,069 | $9.00K | 0.00% | +42,069 | New |
| Bank of America Corp | 52,664 | $10.8K | 0.00% | +3,436+7.0% | Added |
| Bank of Montreal | 54,130 | $11.2K | 0.00% | −65,249−54.7% | Reduced |
| Barclays PLC | 75,254 | $15.5K | 0.00% | +11,951+18.9% | Added |
| Bank of New York Mellon Corp | 75,966 | $15.7K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 84,075 | $17.4K | 0.00% | −913,707−91.6% | Reduced |
| FMR LLC | 99,791 | $20.6K | 0.00% | +59,529+147.9% | Added |
| Susquehanna International Group, LLP | 103,430 | $21.3K | 0.00% | +90,517+701.0% | Added |
| Charles Schwab Investment Management Inc | 111,609 | $23.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 154,800 | $32.0K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 156,442 | $32.3K | 0.00% | +96,681+161.8% | Added |
| Two Sigma Investments, LP | 209,997 | $43.3K | 0.00% | −72,550−25.7% | Reduced |
| Morgan Stanley | 216,485 | $44.7K | 0.00% | −435,896−66.8% | Reduced |
| Boothbay Fund Management, LLC | 233,989 | $48.3K | 0.00% | +1,319+0.6% | Added |
| BNP Paribas Arbitrage, SA | 244,920 | $50.6K | 0.00% | +244,920 | New |
| Northern Trust Corp | 286,310 | $59.1K | 0.00% | +103,026+56.2% | Added |
| Qube Research & Technologies Ltd | 342,159 | $70.6K | 0.00% | +342,159 | New |
| Two Sigma Advisers, LP | 385,500 | $79.6K | 0.00% | −74,800−16.3% | Reduced |
| UBS Group AG | 424,965 | $87.5K | 0.00% | +400,050+1,605.7% | Added |
| State Street Corp | 488,720 | $100.9K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 533,200 | $110.1K | 0.02% | +533,200 | New |
| Goldman Sachs Group Inc | 555,508 | $114.7K | 0.00% | +8,169+1.5% | Added |
| Geode Capital Management, LLC | 885,966 | $182.9K | 0.00% | +117,578+15.3% | Added |
| Ikarian Capital, LLC | 1,058,148 | $218.4K | 0.06% | +1,319+0.1% | Added |
| Vanguard Group Inc | 1,787,422 | $368.2K | 0.00% | +8,159+0.5% | Added |
| Samsara BioCapital, LLC | 1,965,689 | $405.7K | 0.06% | −814,572−29.3% | Reduced |
| BlackRock, Inc. | 3,109,798 | $641.9K | 0.00% | +116,172+3.9% | Added |
| Perceptive Advisors LLC | 12,757,562 | $2.63M | 0.07% | 00.0% | Unchanged |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −4,772,816−100.0% | Sold out |
| Everhart Financial Group, Inc. | 0 | $0 | 0.00% | −252,708−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −159,238−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −110,493−100.0% | Sold out |
| Beacon Pointe Advisors, LLC | 0 | $0 | 0.00% | −77,112−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −54,601−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −17,776−100.0% | Sold out |
| DLK Investment Management, LLC | 0 | $0 | 0.00% | −12,000−100.0% | Sold out |
| Diversified Enterprises, LLC | 0 | $0 | 0.00% | −11,932−100.0% | Sold out |
| National Bank of Canada | 0 | $0 | 0.00% | −3,700−100.0% | Sold out |
| Geneos Wealth Management Inc. | 0 | $0 | 0.00% | −3,538−100.0% | Sold out |
| Advisor Group Holdings, Inc. | 0 | $0 | 0.00% | −1,378−100.0% | Sold out |
| Capital Performance Advisors LLP | 0 | $0 | 0.00% | −533−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −70−100.0% | Sold out |
| Farther Finance Advisors, LLC | 0 | $0 | 0.00% | −38−100.0% | Sold out |
| Diversified, LLC | – | – | – | – | Not filed |