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Fulcrum Therapeutics, Inc.

FULC
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001680581

In the last 90 days, Fulcrum Therapeutics, Inc. insiders filed 2 open-market purchases and 0 sales; 154 institutions reported holding it in 13F filings for Q2 2026, worth $291.3M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Fulcrum Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
117
−1 vs. Q4 2024
Shares held
51.4M
−189.6K (−0.4%) vs. Q4 2024
Total value
$147.8M
−$94.8M (−39.1%) vs. Q4 2024
New holders
18
31 more added
Sold out
19
43 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting FULC on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 117 institutions
Q1 2021: 68 institutionsQ2 2021: 67 institutionsQ3 2021: 101 institutionsQ4 2021: 110 institutionsQ1 2022: 108 institutionsQ2 2022: 102 institutionsQ3 2022: 105 institutionsQ4 2022: 110 institutionsQ1 2023: 116 institutionsQ2 2023: 88 institutionsQ3 2023: 81 institutionsQ4 2023: 101 institutionsQ1 2024: 126 institutionsQ2 2024: 121 institutionsQ3 2024: 130 institutionsQ4 2024: 119 institutionsQ1 2025: 117 institutionsQ2 2025: 122 institutionsQ3 2025: 129 institutionsQ4 2025: 172 institutionsQ1 2026: 169 institutionsQ2 2026: 154 institutions
Value heldQ1 2025: $147.8M
Q1 2021: $317.0MQ2 2021: $280.8MQ3 2021: $1.03BQ4 2021: $657.3MQ1 2022: $929.9MQ2 2022: $196.6MQ3 2022: $422.1MQ4 2022: $368.5MQ1 2023: $172.2MQ2 2023: $183.2MQ3 2023: $250.4MQ4 2023: $412.3MQ1 2024: $569.7MQ2 2024: $402.0MQ3 2024: $196.4MQ4 2024: $243.4MQ1 2025: $147.8MQ2 2025: $374.5MQ3 2025: $494.9MQ4 2025: $762.7MQ1 2026: $550.1MQ2 2026: $291.3M
Institutions holding FULC and their total value by quarter
QuarterHoldersValue
Q2 2026154$291.3M
Q1 2026169$550.1M
Q4 2025172$762.7M
Q3 2025129$494.9M
Q2 2025122$374.5M
Q1 2025117$147.8M
Q4 2024119$243.4M
Q3 2024130$196.4M
Q2 2024121$402.0M
Q1 2024126$569.7M
Q4 2023101$412.3M
Q3 202381$250.4M
Q2 202388$183.2M
Q1 2023116$172.2M
Q4 2022110$368.5M
Q3 2022105$422.1M
Q2 2022102$196.6M
Q1 2022108$929.9M
Q4 2021110$657.3M
Q3 2021101$1.03B
Q2 202167$280.8M
Q1 202168$317.0M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Fulcrum Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding FULC in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Goldman Sachs Group Inc402,600$1.16M0.00%−139,658−25.8%Reduced
ADAR1 Capital Management, LLC490,532$1.41M0.27%+294,284+150.0%Added
D. E. Shaw & Co., Inc.580,661$1.67M0.00%−2,542−0.4%Reduced
Northern Trust Corp640,947$1.85M0.00%−69,374−9.8%Reduced
Exome Asset Management LLC689,137$1.98M1.78%+405,538+143.0%Added
Woodline Partners LP897,617$2.59M0.02%−512,903−36.4%Reduced
Geode Capital Management, LLC1,231,375$3.55M0.00%−63,140−4.9%Reduced
State Street Corp1,252,440$3.61M0.00%+7,121+0.6%Added
Dimensional Fund Advisors LP1,407,049$4.05M0.00%−11,641−0.8%Reduced
Adage Capital Partners GP, L.L.C.3,000,000$8.64M0.02%00.0%Unchanged
Vanguard Group Inc3,220,378$9.27M0.00%−29,229−0.9%Reduced
BlackRock, Inc.4,710,697$13.6M0.00%−458,732−8.9%Reduced
Nantahala Capital Management, LLC4,822,693$13.9M1.15%+42,985+0.9%Added
Suvretta Capital Management, LLC5,067,394$14.6M0.59%+1,728,928+51.8%Added
TCG Crossover Management, LLC5,250,000$15.1M2.06%00.0%Unchanged
Ra Capital Management, L.P.10,229,099$29.5M0.49%00.0%Unchanged
DekaBank Deutsche Girozentrale60,000––00.0%Unchanged
Perceptive Advisors LLC0$00.00%−238,000−100.0%Sold out
Wellington Management Group LLP0$00.00%−172,158−100.0%Sold out
State Board of Administration of Florida Retirement System0$00.00%−130,693−100.0%Sold out
Mackenzie Financial Corp0$00.00%−118,025−100.0%Sold out
LMR Partners LLP0$00.00%−112,500−100.0%Sold out
Altium Capital Management LP0$00.00%−111,812−100.0%Sold out
Nebula Research & Development LLC0$00.00%−75,140−100.0%Sold out
MYDA Advisors LLC0$00.00%−63,970−100.0%Sold out
Bailard, Inc.0$00.00%−35,900−100.0%Sold out
Corton Capital Inc.0$00.00%−23,498−100.0%Sold out
Cantor Fitzgerald, L. P.0$00.00%−20,000−100.0%Sold out
Mariner, LLC0$00.00%−16,516−100.0%Sold out
Winton Group Ltd0$00.00%−12,997−100.0%Sold out
Belvedere Trading LLC0$00.00%−758−100.0%Sold out
C M Bidwell & Associates Ltd0$00.00%−117−100.0%Sold out
HighMark Wealth Management LLC0$00.00%−100−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−95−100.0%Sold out
Larson Financial Group LLC0$00.00%−15−100.0%Sold out
Zurcher Kantonalbank (Zurich Cantonalbank)0$00.00%−3−100.0%Sold out
Nuveen Asset Management, LLC––––Not filed