Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- +1 vs. Q4 2024
- Shares held
- 135.9M
- +8.35M (+6.5%) vs. Q4 2024
- Total value
- $1.85B
- −$751.0M (−28.9%) vs. Q4 2024
- New holders
- 36
- 74 more added
- Sold out
- 35
- 80 more reduced
3 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Camber Capital Management LP | 1,250,000 | $17.0M | 1.06% | −1,000,000−44.4% | Reduced |
| Morgan Stanley | 1,253,603 | $17.0M | 0.00% | +24,463+2.0% | Added |
| Fisher Asset Management, LLC | 1,364,959 | $18.6M | 0.01% | +572,460+72.2% | Added |
| Millennium Management LLC | 1,493,068 | $20.3M | 0.02% | +1,088,844+269.4% | Added |
| Goldman Sachs Group Inc | 1,672,078 | $22.7M | 0.00% | +614,555+58.1% | Added |
| Dimensional Fund Advisors LP | 2,100,856 | $28.6M | 0.01% | +245,820+13.3% | Added |
| Marshall Wace, LLP | 2,188,422 | $29.8M | 0.04% | +399,685+22.3% | Added |
| Geode Capital Management, LLC | 3,037,176 | $41.3M | 0.00% | +101,893+3.5% | Added |
| Norges Bank | 3,047,606 | $41.4M | 0.01% | +1,981,998+186.0% | Added |
| Alliancebernstein L.P. | 3,154,387 | $42.9M | 0.02% | −161,255−4.9% | Reduced |
| Baker Bros. Advisors LP | 3,731,695 | $50.7M | 0.56% | 00.0% | Unchanged |
| Crestline Management, LP | 4,160,732 | $56.6M | 89.45% | −150,000−3.5% | Reduced |
| Price T Rowe Associates Inc | 4,367,234 | $59.4M | 0.01% | +1,308,619+42.8% | Added |
| State Street Corp | 4,460,757 | $60.6M | 0.00% | −84,216−1.9% | Reduced |
| Capital Research Global Investors | 4,765,137 | $64.8M | 0.01% | −712,074−13.0% | Reduced |
| Temasek Holdings (Private) Ltd | 5,355,832 | $72.8M | 0.29% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 6,766,916 | $92.0M | 0.02% | +3,184,042+88.9% | Added |
| FMR LLC | 7,413,354 | $100.8M | 0.01% | −606,392−7.6% | Reduced |
| Wellington Management Group LLP | 11,409,598 | $155.1M | 0.03% | +1,561,647+15.9% | Added |
| Vanguard Group Inc | 11,799,757 | $160.4M | 0.00% | −221,473−1.8% | Reduced |
| Baillie Gifford & Co | 12,090,040 | $164.4M | 0.14% | −223,891−1.8% | Reduced |
| BlackRock, Inc. | 13,834,956 | $188.1M | 0.00% | −85,289−0.6% | Reduced |
| Activest Wealth Management | 0 | $0 | 0.00% | −131−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −548,739−100.0% | Sold out |
| Holocene Advisors, LP | 0 | $0 | 0.00% | −199,072−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −192,563−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −130,445−100.0% | Sold out |
| Fred Alger Management, LLC | 0 | $0 | 0.00% | −91,807−100.0% | Sold out |
| First Trust Advisors LP | 0 | $0 | 0.00% | −65,442−100.0% | Sold out |
| Diadema Partners LP | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −39,015−100.0% | Sold out |
| Fox Run Management, L.L.C. | 0 | $0 | 0.00% | −38,668−100.0% | Sold out |
| Los Angeles Capital Management LLC | 0 | $0 | 0.00% | −22,222−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −21,039−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −21,011−100.0% | Sold out |
| Bryce Point Capital, LLC | 0 | $0 | 0.00% | −20,550−100.0% | Sold out |
| Caption Management, LLC | 0 | $0 | 0.00% | −19,900−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −17,917−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −16,743−100.0% | Sold out |
| Bellevue Group AG | 0 | $0 | 0.00% | −15,700−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −15,694−100.0% | Sold out |
| JustInvest LLC | 0 | $0 | 0.00% | −11,377−100.0% | Sold out |
| Point72 (DIFC) Ltd | 0 | $0 | 0.00% | −7,438−100.0% | Sold out |
| Point72 Hong Kong Ltd | 0 | $0 | 0.00% | −3,175−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −3,029−100.0% | Sold out |
| R Squared Ltd | 0 | $0 | 0.00% | −580−100.0% | Sold out |
| Oarsman Capital, Inc. | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Private Wealth Management Group, LLC | 0 | $0 | 0.00% | −260−100.0% | Sold out |
| Skopos Labs, Inc. | 0 | $0 | 0.00% | −172−100.0% | Sold out |
| Meeder Asset Management Inc | 0 | $0 | 0.00% | −165−100.0% | Sold out |
| SRS Capital Advisors, Inc. | 0 | $0 | 0.00% | −117−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −110−100.0% | Sold out |
| Vista Private Wealth Partners. LLC | 0 | $0 | 0.00% | −80−100.0% | Sold out |
| CVA Family Office, LLC | 0 | $0 | 0.00% | −30−100.0% | Sold out |
| WealthTrak Capital Management LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| IFP Advisors, Inc | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Sandy Spring Bank | 0 | $0 | 0.00% | 0 | Sold out |
| Nuveen Asset Management, LLC | – | – | – | – | Not filed |
| Cassady Schiller Wealth Management, LLC | – | – | – | – | Not filed |
| Global Retirement Partners, LLC | – | – | – | – | Not filed |