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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
−6 vs. Q1 2024
Shares held
123.9M
+3.03M (+2.5%) vs. Q1 2024
Total value
$2.88B
+$396.3M (+16.0%) vs. Q1 2024
New holders
29
84 more added
Sold out
35
60 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 203 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2024: $2.88B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2024.

Institutions holding DNLI in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth25$00.00%+25New
CIBC Private Wealth Group, LLC1$210.00%00.0%Unchanged
Toronto Dominion Bank2$460.00%00.0%Unchanged
Global Retirement Partners, LLC11$2550.00%00.0%Unchanged
First Horizon Advisors, Inc.25$5800.00%00.0%Unchanged
Innealta Capital, LLC30$6960.00%+30New
CVA Family Office, LLC30$6970.00%+30New
Valley National Advisers Inc50$1.00K0.00%+50New
Bell Investment Advisors, Inc52$1.21K0.00%00.0%Unchanged
Allworth Financial LP64$1.37K0.00%−22−25.6%Reduced
Rothschild Investment LLC60$1.39K0.00%+50+500.0%Added
Ronald Blue Trust, Inc.82$1.68K0.00%+82New
Farther Finance Advisors, LLC80$1.76K0.00%+45+128.6%Added
Your Advocates Ltd., LLP100$2.32K0.00%00.0%Unchanged
Versant Capital Management, Inc101$2.35K0.00%−8−7.3%Reduced
Parallel Advisors, LLC112$2.60K0.00%−304−73.1%Reduced
SRS Capital Advisors, Inc.117$2.72K0.00%+117New
Activest Wealth Management131$3.04K0.00%00.0%Unchanged
Principal Securities, Inc.145$3.37K0.00%−586−80.2%Reduced
Massmutual Trust Co FSB154$3.58K0.00%−11−6.7%Reduced
Lindbrook Capital, LLC225$5.22K0.00%−89−28.3%Reduced
City State Bank250$5.80K0.00%00.0%Unchanged
Private Wealth Management Group, LLC260$6.04K0.00%+236+983.3%Added
EverSource Wealth Advisors, LLC317$7.72K0.00%+25+8.6%Added
Comerica Bank415$9.64K0.00%+6+1.5%Added
Huntington National Bank445$10.3K0.00%+71+19.0%Added
Smartleaf Asset Management LLC476$10.9K0.00%+476New
NBC Securities, Inc.532$12.0K0.00%+197+58.8%Added
Signaturefd, LLC534$12.4K0.00%−196−26.8%Reduced
Covestor Ltd578$13.0K0.01%−10,166−94.6%Reduced
Daiwa Securities Group Inc.546$13.0K0.00%00.0%Unchanged
Nemes Rush Group LLC700$16.3K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.850$19.7K0.00%+211+33.0%Added
Pacer Advisors, Inc.862$20.0K0.00%−1,163−57.4%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,001$23.2K0.00%+856+590.3%Added
Bartlett & Co. Wealth Management LLC1,500$34.8K0.00%00.0%Unchanged
CWM, LLC1,499$35.0K0.00%−271−15.3%Reduced
US Bancorp1,616$37.5K0.00%+863+114.6%Added
GAMMA Investing LLC2,057$47.8K0.01%+1,847+879.5%Added
The PNC Financial Services Group, Inc.2,369$55.0K0.00%+714+43.1%Added
Assetmark, Inc3,228$75.0K0.00%−86−2.6%Reduced
KBC Group NV3,603$84.0K0.00%+1,138+46.2%Added
Virtus ETF Advisers LLC4,092$95.0K0.05%+357+9.6%Added
Amalgamated Bank4,192$97.0K0.00%+168+4.2%Added
Mirae Asset Global Investments Co., Ltd.4,258$97.8K0.00%−66,884−94.0%Reduced
Simplex Trading, LLC4,934$114.0K0.00%+6+0.1%Added
Allspring Global Investments Holdings, LLC6,097$141.6K0.00%−63−1.0%Reduced
Quarry LP6,500$150.9K0.06%−500−7.1%Reduced
Point72 Asia (Singapore) Pte. Ltd.8,335$193.5K0.04%+8,335New
BNP Paribas Arbitrage, SA8,366$194.3K0.00%−63,739−88.4%Reduced
MONECO Advisors, LLC8,700$202.0K0.03%+8,700New
E Fund Management Co., Ltd.9,200$213.6K0.01%−11,352−55.2%Reduced
Prelude Capital Management, LLC10,343$240.2K0.02%−26−0.3%Reduced
JustInvest LLC10,790$249.1K0.00%+10,790New
Engineers Gate Manager LP11,130$258.4K0.01%−20,226−64.5%Reduced
Cetera Investment Advisers11,280$261.9K0.00%+11,280New
Letko, Brosseau & Associates Inc11,350$263.5K0.00%+11,350New
Ameritas Investment Partners, Inc.12,230$284.0K0.01%00.0%Unchanged
Public Employees Retirement Association of Colorado12,238$284.0K0.00%00.0%Unchanged
Stifel Financial Corp12,847$298.3K0.00%−26−0.2%Reduced
Great West Life Assurance Co13,434$312.0K0.00%+3,710+38.2%Added
Pictet Asset Management Holding SA13,796$320.3K0.00%00.0%Unchanged
SG Americas Securities, LLC13,808$321.0K0.00%+6,667+93.4%Added
Victory Capital Management Inc15,133$351.4K0.00%+390+2.6%Added
Royal Bank of Canada15,279$354.0K0.00%+8,220+116.4%Added
China Universal Asset Management Co., Ltd.16,753$389.0K0.05%−9,968−37.3%Reduced
STRS Ohio17,400$404.0K0.00%+4,400+33.8%Added
First Trust Advisors LP19,250$447.0K0.00%+19,250New
Guggenheim Capital LLC19,919$462.5K0.00%+200+1.0%Added
Tower Research Capital LLC (TRC)20,832$483.7K0.01%+19,407+1,361.9%Added
Envestnet Asset Management Inc21,141$490.9K0.00%−1,155−5.2%Reduced
NEOS Investment Management LLC21,648$502.7K0.02%00.0%Unchanged
SEI Investments Co22,670$526.4K0.00%+10,598+87.8%Added
Russell Investments Group, Ltd.22,914$532.1K0.00%−62,714−73.2%Reduced
ClariVest Asset Management LLC22,964$533.2K0.05%−24,784−51.9%Reduced
Polar Asset Management Partners Inc.24,100$559.6K0.01%+24,100New
Fox Run Management, L.L.C.24,390$566.3K0.11%+24,390New
ProShare Advisors LLC24,798$575.8K0.00%−6,407−20.5%Reduced
Hamilton Lane Advisors LLC25,657$595.8K0.48%+25,657New
Teacher Retirement System of Texas25,952$603.0K0.00%+1,346+5.5%Added
Zurcher Kantonalbank (Zurich Cantonalbank)26,403$613.1K0.00%+1,372+5.5%Added
Erste Asset Management GmbH26,900$617.9K0.01%00.0%Unchanged
Algert Global LLC26,655$618.9K0.02%−55,345−67.5%Reduced
Fred Alger Management, LLC27,014$627.3K0.00%+27,014New
HSBC Holdings PLC29,642$668.5K0.00%+13,454+83.1%Added
Brevan Howard Capital Management LP29,357$681.7K0.04%+29,357New
Profund Advisors LLC29,373$682.0K0.03%−39,101−57.1%Reduced
D. E. Shaw & Co., Inc.29,721$690.1K0.00%−86,544−74.4%Reduced
UBS Oconnor LLC31,517$731.8K0.02%+6,484+25.9%Added
Arizona State Retirement System33,114$768.9K0.01%+2,730+9.0%Added
State Board of Administration of Florida Retirement System34,168$793.4K0.00%+1,880+5.8%Added
Dana Investment Advisors, Inc.34,269$795.7K0.03%+5,513+19.2%Added
Eisler Capital (US) LLC35,861$832.7K0.16%+1,381+4.0%Added
Ironwood Investment Management LLC36,229$841.2K0.45%+165+0.5%Added
Man Group plc37,545$871.8K0.00%+37,545New
ADAR1 Capital Management, LLC38,000$882.4K0.18%+36,000+1,800.0%Added
HighTower Advisors, LLC37,914$884.0K0.00%−1,306−3.3%Reduced
Y-Intercept (Hong Kong) Ltd39,192$910.0K0.05%+39,192New
Handelsbanken Fonder AB39,500$917.0K0.00%+15,600+65.3%Added
Creative Planning43,033$999.2K0.00%+3,458+8.7%Added