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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
211
+3 vs. Q4 2023
Shares held
122.4M
+7.40M (+6.4%) vs. Q4 2023
Total value
$2.51B
+$47.5M (+1.9%) vs. Q4 2023
New holders
36
76 more added
Sold out
33
69 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 211 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2024: $2.51B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2023.

Institutions holding DNLI in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Geode Capital Management, LLC2,759,633$56.6M0.01%+100,337+3.8%Added
Baker Bros. Advisors LP3,731,695$76.6M0.96%+1,124,499+43.1%Added
Takeda Pharmaceutical Co Ltd4,214,559$86.5M29.92%00.0%Unchanged
Crestline Management, LP5,210,732$106.9M10.12%−450,000−7.9%Reduced
Temasek Holdings (Private) Ltd5,706,345$117.1M0.65%−1,189,647−17.3%Reduced
Capital Research Global Investors6,049,957$124.1M0.03%+3,140,429+107.9%Added
State Street Corp6,323,872$129.8M0.01%+837,924+15.3%Added
Wellington Management Group LLP8,269,949$169.7M0.03%+995,232+13.7%Added
Vanguard Group Inc10,968,293$225.1M0.00%+133,810+1.2%Added
BlackRock Inc.12,199,856$250.3M0.01%+656,410+5.7%Added
Baillie Gifford & Co14,041,228$288.1M0.22%−219,496−1.5%Reduced
Federated Hermes, Inc.0$00.00%−1,351,900−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−644,406−100.0%Sold out
Braidwell LP0$00.00%−461,769−100.0%Sold out
Eagle Asset Management Inc0$00.00%−315,520−100.0%Sold out
Mitsubishi UFJ Trust & Banking Corp0$00.00%−246,190−100.0%Sold out
California Public Employees Retirement System0$00.00%−176,131−100.0%Sold out
Renaissance Technologies LLC0$00.00%−161,946−100.0%Sold out
Schroder Investment Management Group0$00.00%−154,000−100.0%Sold out
Neuberger Berman Group LLC0$00.00%−144,461−100.0%Sold out
Pathway Capital Management, LP0$00.00%−69,450−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−65,105−100.0%Sold out
Harbor Capital Advisors, Inc.0$00.00%−60,304−100.0%Sold out
Healthcare of Ontario Pension Plan Trust Fund0$00.00%−46,000−100.0%Sold out
HRT Financial LP0$00.00%−44,292−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−27,429−100.0%Sold out
VELA Investment Management, LLC0$00.00%−26,145−100.0%Sold out
Landscape Capital Management, L.L.C.0$00.00%−24,318−100.0%Sold out
Levin Capital Strategies, L.P.0$00.00%−24,000−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−18,327−100.0%Sold out
Walleye Capital LLC0$00.00%−16,728−100.0%Sold out
Virtu Financial LLC0$00.00%−15,576−100.0%Sold out
Arthur M. Cohen & Associates, LLC0$00.00%−10,564−100.0%Sold out
Quest Partners LLC0$00.00%−9,965−100.0%Sold out
Brandywine Managers, LLC0$00.00%−9,601−100.0%Sold out
Aquatic Capital Management LLC0$00.00%−8,300−100.0%Sold out
Tao Capital Management LP0$00.00%−3,042−100.0%Sold out
Caption Management, LLC0$00.00%−3,000−100.0%Sold out
Advisory Services Network, LLC0$00.00%−309−100.0%Sold out
Morton Brown Family Wealth, LLC0$00.00%−298−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−77−100.0%Sold out
Glassman Wealth Services0$00.00%−29−100.0%Sold out
Quadrant Capital Group LLC0$00.00%−19−100.0%Sold out
Institutional & Family Asset Management, LLC0$00.00%−11−100.0%Sold out
Bartlett & Co. LLC––––Not filed