Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q3 2023
Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 195
- −6 vs. Q2 2023
- Shares held
- 108.6M
- +2.04M (+1.9%) vs. Q2 2023
- Total value
- $2.24B
- −$898.3M (−28.6%) vs. Q2 2023
- New holders
- 29
- 77 more added
- Sold out
- 35
- 57 more reduced
2 institutions that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| HighTower Advisors, LLC | 54,332 | $1.13M | 0.00% | −185−0.3% | Reduced |
| Guggenheim Capital LLC | 57,370 | $1.18M | 0.01% | +3,584+6.7% | Added |
| UBS Oconnor LLC | 58,952 | $1.22M | 0.02% | +10,000+20.4% | Added |
| American International Group, Inc. | 58,962 | $1.22M | 0.01% | +2,096+3.7% | Added |
| Franklin Resources Inc | 59,351 | $1.22M | 0.00% | +59,351 | New |
| Citadel Advisors LLC | 61,905 | $1.28M | 0.00% | +5,802+10.3% | Added |
| MetLife Investment Management | 62,264 | $1.28M | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 64,210 | $1.35M | 0.00% | +4,410+7.4% | Added |
| AIA Group Ltd | 68,447 | $1.41M | 0.07% | +12,203+21.7% | Added |
| Mirae Asset Global Investments Co., Ltd. | 69,674 | $1.44M | 0.00% | −40.0% | Reduced |
| Northwest & Ethical Investments L.P. | 74,768 | $1.54M | 0.05% | 00.0% | Unchanged |
| Susquehanna Fundamental Investments, LLC | 81,308 | $1.68M | 0.11% | −9,941−10.9% | Reduced |
| Invesco Ltd. | 88,353 | $1.82M | 0.00% | −4,568−4.9% | Reduced |
| Susquehanna International Group, LLP | 93,803 | $1.94M | 0.00% | −23,789−20.2% | Reduced |
| State of Wisconsin Investment Board | 97,856 | $2.02M | 0.01% | −733−0.7% | Reduced |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.06M | 0.04% | 00.0% | Unchanged |
| Alps Advisors Inc | 101,400 | $2.09M | 0.02% | +780+0.8% | Added |
| Legal & General Group Plc | 105,825 | $2.18M | 0.00% | +933+0.9% | Added |
| State of New Jersey Common Pension Fund D | 107,089 | $2.21M | 0.01% | +28,836+36.8% | Added |
| UBS Group AG | 109,696 | $2.26M | 0.00% | −22,244−16.9% | Reduced |
| Squarepoint Ops LLC | 110,069 | $2.27M | 0.01% | +110,069 | New |
| Manufacturers Life Insurance Company, The | 113,398 | $2.34M | 0.00% | −5,551−4.7% | Reduced |
| Russell Investments Group, Ltd. | 114,058 | $2.35M | 0.00% | +7,244+6.8% | Added |
| Deutsche Bank AG | 116,498 | $2.40M | 0.00% | −28,379−19.6% | Reduced |
| Millennium Management LLC | 118,351 | $2.44M | 0.00% | −359,835−75.3% | Reduced |
| California State Teachers Retirement System | 122,904 | $2.54M | 0.00% | −12,611−9.3% | Reduced |
| Pier Capital, LLC | 125,080 | $2.58M | 0.42% | −2,048−1.6% | Reduced |
| New York State Common Retirement Fund | 129,853 | $2.68M | 0.00% | +3,954+3.1% | Added |
| TD Asset Management Inc | 135,000 | $2.79M | 0.00% | +50,578+59.9% | Added |
| Wells Fargo & Company | 135,926 | $2.80M | 0.00% | −26,628−16.4% | Reduced |
| Alliancebernstein L.P. | 136,760 | $2.82M | 0.00% | −41,960−23.5% | Reduced |
| Citigroup Inc | 138,309 | $2.85M | 0.00% | +30,282+28.0% | Added |
| TCW Group Inc | 141,924 | $2.93M | 0.04% | +51,953+57.7% | Added |
| International Biotechnology Trust PLC | 154,000 | $3.17M | 1.07% | −34,000−18.1% | Reduced |
| Prudential Financial Inc | 153,828 | $3.17M | 0.00% | +29,506+23.7% | Added |
| BNP Paribas Arbitrage, SA | 162,826 | $3.36M | 0.01% | +55,344+51.5% | Added |
| Barclays PLC | 166,507 | $3.44M | 0.00% | +8,045+5.1% | Added |
| JPMorgan Chase & Co | 167,964 | $3.47M | 0.00% | +9,972+6.3% | Added |
| Rhumbline Advisers | 169,124 | $3.49M | 0.00% | +7,142+4.4% | Added |
| California Public Employees Retirement System | 176,131 | $3.63M | 0.00% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 218,194 | $4.50M | 0.05% | −1,254−0.6% | Reduced |
| Rafferty Asset Management, LLC | 229,313 | $4.73M | 0.03% | −19,213−7.7% | Reduced |
| Swiss National Bank | 240,800 | $4.97M | 0.00% | +2,700+1.1% | Added |
| Sectoral Asset Management Inc | 254,941 | $5.26M | 1.02% | +9,650+3.9% | Added |
| Voya Investment Management LLC | 264,616 | $5.46M | 0.01% | +1,109+0.4% | Added |
| Eagle Asset Management Inc | 289,133 | $5.96M | 0.04% | −5,658−1.9% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 290,960 | $6.00M | 0.02% | +1,380+0.5% | Added |
| Bank of America Corp | 295,794 | $6.10M | 0.00% | +25,549+9.5% | Added |
| Wasatch Advisors Inc | 321,467 | $6.63M | 0.04% | −510,830−61.4% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 348,203 | $7.18M | 0.05% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 348,497 | $7.19M | 0.02% | +200,000+134.7% | Added |
| AXA S.A. | 354,529 | $7.31M | 0.03% | −3,853−1.1% | Reduced |
| Candriam Luxembourg S.C.A. | 357,878 | $7.38M | 0.06% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 363,665 | $7.50M | 0.00% | −1,791−0.5% | Reduced |
| Clarius Group, LLC | 378,262 | $7.80M | 0.74% | −50.0% | Reduced |
| Artisan Partners Limited Partnership | 406,622 | $8.39M | 0.01% | −10,161−2.4% | Reduced |
| Goldman Sachs Group Inc | 407,393 | $8.40M | 0.00% | −237,521−36.8% | Reduced |
| Man Group plc | – | $8.74M | 0.03% | – | – |
| Renaissance Technologies LLC | 467,851 | $9.65M | 0.02% | +510.0% | Added |
| American Century Companies Inc | 474,336 | $9.79M | 0.01% | +427+0.1% | Added |
| Pictet Asset Management Holding SA | 589,499 | $12.2M | 0.02% | +589,499 | New |
| Deerfield Management Company, L.P. (Series C) | 594,989 | $12.3M | 0.27% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 621,850 | $12.8M | 0.23% | +308,443+98.4% | Added |
| Cercano Management LLC | 625,000 | $12.9M | 0.46% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 643,300 | $13.3M | 0.01% | +76,159+13.4% | Added |
| T. Rowe Price Investment Management, Inc. | 647,013 | $13.3M | 0.01% | 00.0% | Unchanged |
| Principal Financial Group Inc | 680,078 | $14.0M | 0.01% | −6,414−0.9% | Reduced |
| ARCH Venture Management, LLC | 693,749 | $14.3M | 9.30% | 00.0% | Unchanged |
| Artal Group S.A. | 802,899 | $16.6M | 0.72% | 00.0% | Unchanged |
| Norges Bank | 803,892 | $16.6M | 0.00% | +223,558+38.5% | Added |
| Woodline Partners LP | 851,489 | $17.6M | 0.21% | +739,277+658.8% | Added |
| Dimensional Fund Advisors LP | 973,234 | $20.1M | 0.01% | +218,433+28.9% | Added |
| Charles Schwab Investment Management Inc | 981,059 | $20.2M | 0.01% | +113,428+13.1% | Added |
| Morgan Stanley | 981,569 | $20.2M | 0.00% | −95,317−8.9% | Reduced |
| Polar Capital Holdings Plc | 1,007,086 | $20.8M | 0.15% | 00.0% | Unchanged |
| FMR LLC | 1,058,497 | $21.8M | 0.00% | −21,360−2.0% | Reduced |
| Northern Trust Corp | 1,116,742 | $23.0M | 0.00% | +27,044+2.5% | Added |
| Yiheng Capital Management, L.P. | 1,150,684 | $23.7M | 2.14% | 00.0% | Unchanged |
| Gilder Gagnon Howe & Co LLC | 1,246,199 | $25.7M | 0.39% | −333,746−21.1% | Reduced |
| Casdin Capital, LLC | 1,300,000 | $26.8M | 2.99% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 1,351,900 | $27.9M | 0.07% | +288,400+27.1% | Added |
| Credit Suisse AG | 1,567,309 | $32.3M | 0.03% | −5,739−0.4% | Reduced |
| Bank of New York Mellon Corp | 1,963,688 | $40.5M | 0.01% | −26,019−1.3% | Reduced |
| Baker Bros. Advisors LP | 2,292,003 | $47.3M | 0.27% | +836,681+57.5% | Added |
| Geode Capital Management, LLC | 2,531,835 | $52.2M | 0.01% | +213,538+9.2% | Added |
| Flagship Pioneering Inc. | 2,619,968 | $54.0M | 3.92% | 00.0% | Unchanged |
| Capital Research Global Investors | 2,880,323 | $59.4M | 0.02% | +42,671+1.5% | Added |
| Price T Rowe Associates Inc | 2,891,950 | $59.7M | 0.01% | −553,362−16.1% | Reduced |
| State Street Corp | 4,275,328 | $88.2M | 0.00% | −193,163−4.3% | Reduced |
| Crestline Management, LP | 5,960,732 | $123.0M | 14.69% | −150,000−2.5% | Reduced |
| Temasek Holdings (Private) Ltd | 6,895,992 | $142.3M | 0.85% | 00.0% | Unchanged |
| Wellington Management Group LLP | 7,288,960 | $150.4M | 0.03% | +250,784+3.6% | Added |
| Vanguard Group Inc | 10,597,781 | $218.6M | 0.01% | +354,798+3.5% | Added |
| BlackRock Inc. | 10,885,296 | $224.6M | 0.01% | +779,021+7.7% | Added |
| Baillie Gifford & Co | 14,681,027 | $302.9M | 0.28% | −162,743−1.1% | Reduced |
| Avidity Partners Management LP | 0 | $0 | 0.00% | −282,752−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −223,471−100.0% | Sold out |
| Platinum Investment Management Ltd | 0 | $0 | 0.00% | −55,341−100.0% | Sold out |
| Hamilton Lane Advisors LLC | 0 | $0 | 0.00% | −52,129−100.0% | Sold out |
| Bellevue Group AG | 0 | $0 | 0.00% | −44,050−100.0% | Sold out |