Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 200
- +13 vs. Q2 2022
- Shares held
- 92.4M
- −257.0K (−0.3%) vs. Q2 2022
- Total value
- $2.84B
- +$108.6M (+4.0%) vs. Q2 2022
- New holders
- 32
- 78 more added
- Sold out
- 19
- 56 more reduced
1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| International Biotechnology Trust PLC | 38,000 | $1.17M | 0.37% | +36,882+3,298.9% | Added |
| Cubist Systematic Strategies, LLC | 38,341 | $1.18M | 0.01% | −33,563−46.7% | Reduced |
| Envestnet Asset Management Inc | 41,516 | $1.27M | 0.00% | +11,073+36.4% | Added |
| Voloridge Investment Management, LLC | 42,356 | $1.30M | 0.01% | −5,702−11.9% | Reduced |
| UBS Group AG | 42,454 | $1.30M | 0.00% | +36,079+565.9% | Added |
| Toronto Dominion Bank | 42,650 | $1.31M | 0.00% | +42,648+2,132,400.0% | Added |
| Los Angeles Capital Management LLC | 42,741 | $1.31M | 0.01% | −1,178−2.7% | Reduced |
| American International Group, Inc. | 46,777 | $1.44M | 0.01% | +661+1.4% | Added |
| Mirae Asset Global Investments Co., Ltd. | 48,898 | $1.50M | 0.00% | +13,664+38.8% | Added |
| ClariVest Asset Management LLC | 49,380 | $1.51M | 0.07% | −5,258−9.6% | Reduced |
| Guggenheim Capital LLC | 50,435 | $1.55M | 0.01% | −10,572−17.3% | Reduced |
| Platinum Investment Management Ltd | 50,971 | $1.56M | 0.07% | 00.0% | Unchanged |
| MetLife Investment Management | 52,427 | $1.61M | 0.01% | +2,035+4.0% | Added |
| DekaBank Deutsche Girozentrale | 59,800 | $1.74M | 0.01% | 00.0% | Unchanged |
| Citadel Advisors LLC | 63,537 | $1.95M | 0.00% | −242,465−79.2% | Reduced |
| Putnam Investments LLC | 64,044 | $1.97M | 0.00% | −232−0.4% | Reduced |
| Wells Fargo & Company | 64,887 | $1.99M | 0.00% | −4,319−6.2% | Reduced |
| Alps Advisors Inc | 67,323 | $2.07M | 0.02% | −5,617−7.7% | Reduced |
| Natixis | 69,030 | $2.12M | 0.01% | 00.0% | Unchanged |
| HRT Financial LP | 77,628 | $2.38M | 0.03% | +54,028+228.9% | Added |
| Invesco Ltd. | 77,895 | $2.39M | 0.00% | +4,229+5.7% | Added |
| State of New Jersey Common Pension Fund D | 78,253 | $2.40M | 0.01% | −13,645−14.8% | Reduced |
| Northwest & Ethical Investments L.P. | 79,880 | $2.45M | 0.10% | 00.0% | Unchanged |
| Legal & General Group Plc | 86,017 | $2.64M | 0.00% | −486−0.6% | Reduced |
| Capital Research Global Investors | 87,767 | $2.65M | 0.00% | +87,767 | New |
| State of Wisconsin Investment Board | 87,556 | $2.69M | 0.01% | +417+0.5% | Added |
| TD Asset Management Inc | 94,123 | $2.76M | 0.00% | −27,100−22.4% | Reduced |
| Susquehanna International Group, LLP | 96,627 | $2.97M | 0.01% | +86,101+818.0% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $3.06M | 0.08% | 00.0% | Unchanged |
| Deutsche Bank AG | 100,850 | $3.10M | 0.00% | −9,447−8.6% | Reduced |
| Jump Financial, LLC | 102,152 | $3.13M | 0.12% | +87,855+614.5% | Added |
| Russell Investments Group, Ltd. | 106,861 | $3.28M | 0.01% | +18,631+21.1% | Added |
| Manufacturers Life Insurance Company, The | 110,257 | $3.29M | 0.00% | −10,030−8.3% | Reduced |
| JPMorgan Chase & Co | 108,354 | $3.33M | 0.00% | +8,329+8.3% | Added |
| BNP Paribas Arbitrage, SA | 108,569 | $3.33M | 0.01% | +86,237+386.2% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 112,532 | $3.45M | 0.02% | +112,532 | New |
| California State Teachers Retirement System | 112,963 | $3.47M | 0.01% | −1,921−1.7% | Reduced |
| Integral Health Asset Management, LLC | 115,000 | $3.53M | 0.72% | +115,000 | New |
| Ensign Peak Advisors, Inc | 122,647 | $3.76M | 0.01% | +36,975+43.2% | Added |
| Castleark Management LLC | 127,460 | $3.91M | 0.22% | +127,460 | New |
| Rhumbline Advisers | 127,933 | $3.93M | 0.01% | +10,458+8.9% | Added |
| New York State Common Retirement Fund | 144,905 | $4.45M | 0.01% | +4,076+2.9% | Added |
| Alliancebernstein L.P. | 154,960 | $4.76M | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 165,936 | $5.09M | 0.01% | −64,894−28.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 177,196 | $5.44M | 0.06% | +177,196 | New |
| Two Sigma Advisers, LP | 183,800 | $5.64M | 0.02% | +23,300+14.5% | Added |
| Citigroup Inc | 192,642 | $5.91M | 0.01% | +80,828+72.3% | Added |
| California Public Employees Retirement System | 199,855 | $6.13M | 0.01% | −2,322−1.1% | Reduced |
| Swiss National Bank | 204,100 | $6.26M | 0.00% | +2,700+1.3% | Added |
| Rafferty Asset Management, LLC | 207,368 | $6.36M | 0.07% | +105,897+104.4% | Added |
| Bank of America Corp | 220,217 | $6.76M | 0.00% | +101,150+85.0% | Added |
| Tekla Capital Management LLC | 222,420 | $6.83M | 0.28% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 243,350 | $7.47M | 1.47% | +41,250+20.4% | Added |
| AXA S.A. | 248,772 | $7.63M | 0.03% | +1,081+0.4% | Added |
| Eagle Asset Management Inc | 255,460 | $7.84M | 0.05% | −8,244−3.1% | Reduced |
| Clarius Group, LLC | 260,604 | $8.00M | 0.80% | +232,085+813.8% | Added |
| Two Sigma Investments, LP | 261,170 | $8.02M | 0.03% | +196,846+306.0% | Added |
| Bamco Inc | 274,862 | $8.44M | 0.03% | −843−0.3% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 291,308 | $8.94M | 0.07% | +78,485+36.9% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 307,460 | $9.44M | 0.03% | −7,430−2.4% | Reduced |
| Barclays PLC | 325,467 | $9.99M | 0.01% | −43,304−11.7% | Reduced |
| Nuveen Asset Management, LLC | 351,459 | $10.8M | 0.00% | −8,699−2.4% | Reduced |
| Candriam Luxembourg S.C.A. | 357,878 | $11.0M | 0.08% | +34,996+10.8% | Added |
| Wasatch Advisors Inc | 359,473 | $11.0M | 0.08% | +17,799+5.2% | Added |
| Renaissance Technologies LLC | 392,200 | $12.0M | 0.02% | +138,700+54.7% | Added |
| T. Rowe Price Investment Management, Inc. | 422,357 | $13.0M | 0.01% | +422,357 | New |
| Artisan Partners Limited Partnership | 443,101 | $13.6M | 0.02% | −7,588−1.7% | Reduced |
| Woodline Partners LP | 444,256 | $13.6M | 0.20% | +263,284+145.5% | Added |
| American Century Companies Inc | 472,374 | $14.5M | 0.01% | +3,093+0.7% | Added |
| Millennium Management LLC | 496,184 | $15.2M | 0.02% | −149,152−23.1% | Reduced |
| UBS Asset Management Americas Inc | 530,204 | $16.3M | 0.01% | +42,799+8.8% | Added |
| Principal Financial Group Inc | 545,871 | $16.8M | 0.01% | +278,139+103.9% | Added |
| Baker Bros. Advisors LP | 588,738 | $18.1M | 0.12% | 00.0% | Unchanged |
| Artal Group S.A. | 600,000 | $18.4M | 0.96% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 609,839 | $18.7M | 0.01% | −281,839−31.6% | Reduced |
| Point72 Asset Management, L.P. | 633,000 | $19.4M | 0.08% | +633,000 | New |
| Federated Hermes, Inc. | 656,593 | $20.2M | 0.06% | −12,336−1.8% | Reduced |
| Marshall Wace, LLP | 675,870 | $20.7M | 0.05% | −141,780−17.3% | Reduced |
| Morgan Stanley | 681,332 | $20.9M | 0.00% | +258,321+61.1% | Added |
| Goldman Sachs Group Inc | 728,272 | $22.4M | 0.01% | +307,530+73.1% | Added |
| Charles Schwab Investment Management Inc | 730,880 | $22.4M | 0.01% | −642−0.1% | Reduced |
| Northern Trust Corp | 889,968 | $27.3M | 0.01% | −650−0.1% | Reduced |
| Norges Bank | 943,404 | $29.0M | 0.01% | +111,595+13.4% | Added |
| Casdin Capital, LLC | 995,000 | $30.5M | 2.02% | −505,000−33.7% | Reduced |
| Pictet Asset Management SA | 1,003,185 | $30.8M | 0.05% | −11,973−1.2% | Reduced |
| Yiheng Capital Management, L.P. | 1,014,684 | $31.1M | 2.93% | 00.0% | Unchanged |
| Credit Suisse AG | 1,611,429 | $49.5M | 0.06% | −348,596−17.8% | Reduced |
| Geode Capital Management, LLC | 1,776,164 | $54.5M | 0.01% | +69,583+4.1% | Added |
| Gilder Gagnon Howe & Co LLC | 1,863,277 | $57.2M | 1.00% | −93,543−4.8% | Reduced |
| Bank of New York Mellon Corp | 1,895,292 | $58.2M | 0.01% | +27,162+1.5% | Added |
| FMR LLC | 2,452,456 | $75.3M | 0.01% | −417,284−14.5% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $80.4M | 3.38% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,478,368 | $106.8M | 0.02% | −1,131,809−24.6% | Reduced |
| ARCH Venture Management, LLC | 3,668,749 | $112.6M | 14.60% | −1,500,000−29.0% | Reduced |
| State Street Corp | 4,192,228 | $128.7M | 0.01% | +441,528+11.8% | Added |
| Temasek Holdings (Private) Ltd | 5,576,041 | $171.1M | 1.02% | +206,554+3.8% | Added |
| Crestline Management, LP | 7,160,732 | $219.8M | 29.71% | −300,000−4.0% | Reduced |
| Vanguard Group Inc | 8,402,031 | $257.9M | 0.01% | +99,530+1.2% | Added |
| BlackRock Inc. | 8,598,212 | $263.9M | 0.01% | −186,420−2.1% | Reduced |
| Baillie Gifford & Co | 14,715,051 | $451.6M | 0.47% | −154,323−1.0% | Reduced |