Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q3 2021
Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 214
- +6 vs. Q2 2021
- Shares held
- 84.8M
- +4.69M (+5.8%) vs. Q2 2021
- Total value
- $4.28B
- −$2.00B (−31.9%) vs. Q2 2021
- New holders
- 37
- 81 more added
- Sold out
- 31
- 65 more reduced
2 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Mercer Global Advisors Inc | 19,533 | $985.0K | 0.01% | +19,533 | New |
| Polianta Ltd | 19,800 | $998.0K | 0.46% | +19,800 | New |
| Mark Asset Management LP | 20,529 | $1.04M | 0.16% | −18,310−47.1% | Reduced |
| Arizona State Retirement System | 21,458 | $1.08M | 0.01% | +270+1.3% | Added |
| Victory Capital Management Inc | 21,708 | $1.09M | 0.00% | −20,413−48.5% | Reduced |
| Duality Advisers, LP | 23,045 | $1.16M | 0.09% | +23,045 | New |
| Metropolitan Life Insurance Co | 24,089 | $1.22M | 0.02% | −708−2.9% | Reduced |
| Envestnet Asset Management Inc | 26,251 | $1.32M | 0.00% | +26,251 | New |
| Concentric Wealth Management, LLC | 27,967 | $1.41M | 0.43% | +8,621+44.6% | Added |
| Virginia Retirement Systems Et Al | 28,600 | $1.44M | 0.01% | +6,400+28.8% | Added |
| Erste Asset Management GmbH | 30,600 | $1.51M | 0.03% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 30,019 | $1.51M | 0.00% | +600+2.0% | Added |
| Platinum Investment Management Ltd | 30,791 | $1.55M | 0.04% | 00.0% | Unchanged |
| STRS Ohio | 30,900 | $1.56M | 0.01% | −300−1.0% | Reduced |
| SG Americas Securities, LLC | 30,895 | $1.56M | 0.01% | +13,625+78.9% | Added |
| MetLife Investment Management | 32,389 | $1.63M | 0.01% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 32,998 | $1.67M | 0.00% | −31,211−48.6% | Reduced |
| Voya Investment Management LLC | 35,591 | $1.80M | 0.00% | −174−0.5% | Reduced |
| Tao Capital Management LP | 38,949 | $1.97M | 0.52% | +38,949 | New |
| ProShare Advisors LLC | 39,837 | $2.01M | 0.01% | −5,525−12.2% | Reduced |
| Los Angeles Capital Management LLC | 41,522 | $2.10M | 0.01% | +8,090+24.2% | Added |
| Millennium Management LLC | 41,842 | $2.11M | 0.00% | +22,399+115.2% | Added |
| Macquarie Group Ltd | 41,910 | $2.11M | 0.00% | 00.0% | Unchanged |
| University of Texas/Texas Am Investment Managment Co | 41,918 | $2.12M | 1.21% | +41,918 | New |
| D. E. Shaw & Co., Inc. | 45,413 | $2.29M | 0.00% | −38,172−45.7% | Reduced |
| Manufacturers Life Insurance Company, The | 46,935 | $2.37M | 0.00% | −4,398−8.6% | Reduced |
| Invesco Ltd. | 48,218 | $2.43M | 0.00% | −335,347−87.4% | Reduced |
| American International Group, Inc. | 49,797 | $2.51M | 0.01% | −1,183−2.3% | Reduced |
| Jupiter Asset Management Ltd | 50,023 | $2.52M | 0.03% | +50,023 | New |
| DekaBank Deutsche Girozentrale | 52,900 | $2.61M | 0.01% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 52,097 | $2.63M | 0.00% | +32,872+171.0% | Added |
| Polar Capital Holdings Plc | 53,835 | $2.72M | 0.01% | +5,037+10.3% | Added |
| Soros Capital Management LLC | 54,000 | $2.72M | 0.55% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 54,308 | $2.74M | 0.01% | +3,448+6.8% | Added |
| Tygh Capital Management, Inc. | 54,335 | $2.74M | 0.37% | +54,335 | New |
| Rafferty Asset Management, LLC | 60,361 | $3.04M | 0.02% | +25,581+73.6% | Added |
| Citadel Advisors LLC | 63,011 | $3.18M | 0.00% | +63,011 | New |
| Candriam Luxembourg S.C.A. | 63,781 | $3.22M | 0.02% | 00.0% | Unchanged |
| UBS Group AG | 64,480 | $3.25M | 0.00% | +62,043+2,545.9% | Added |
| Russell Investments Group, Ltd. | 65,351 | $3.28M | 0.01% | +1,594+2.5% | Added |
| Castleark Management LLC | 66,145 | $3.34M | 0.13% | +37,105+127.8% | Added |
| CastleArk Alternatives, LLC | 66,145 | $3.34M | 0.13% | +66,145 | New |
| Ensign Peak Advisors, Inc | 66,348 | $3.35M | 0.01% | +24,406+58.2% | Added |
| Barclays PLC | 70,965 | $3.58M | 0.00% | +47,204+198.7% | Added |
| ClariVest Asset Management LLC | 71,466 | $3.61M | 0.12% | −3,779−5.0% | Reduced |
| Putnam Investments LLC | 71,701 | $3.62M | 0.01% | −170.0% | Reduced |
| Integral Health Asset Management, LLC | 75,000 | $3.78M | 1.09% | −6,000−7.4% | Reduced |
| Legal & General Group Plc | 77,528 | $3.91M | 0.00% | +15,284+24.6% | Added |
| Bank of America Corp | 77,846 | $3.92M | 0.00% | +14,094+22.1% | Added |
| First Trust Advisors LP | 80,453 | $4.06M | 0.00% | +19,135+31.2% | Added |
| AQR Capital Management LLC | 82,049 | $4.14M | 0.01% | +2,765+3.5% | Added |
| Baker Bros. Advisors LP | 88,738 | $4.48M | 0.02% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 95,600 | $4.82M | 0.01% | +84,100+731.3% | Added |
| Arrowstreet Capital, Limited Partnership | 96,868 | $4.89M | 0.01% | +96,868 | New |
| Rhumbline Advisers | 97,405 | $4.91M | 0.01% | +2,550+2.7% | Added |
| AIA Group Ltd | 98,441 | $4.97M | 0.28% | +16,550+20.2% | Added |
| JPMorgan Chase & Co | 98,510 | $4.97M | 0.00% | +7,630+8.4% | Added |
| Edmond de Rothschild Holding S.A. | 100,000 | $5.04M | 0.12% | +22,800+29.5% | Added |
| Citigroup Inc | 109,025 | $5.50M | 0.01% | +43,778+67.1% | Added |
| Two Sigma Investments, LP | 113,671 | $5.74M | 0.02% | −105,744−48.2% | Reduced |
| California State Teachers Retirement System | 113,735 | $5.74M | 0.01% | −11,644−9.3% | Reduced |
| Deutsche Bank AG | 116,016 | $5.85M | 0.00% | −1,022−0.9% | Reduced |
| State of Wisconsin Investment Board | 124,000 | $6.26M | 0.01% | +1,300+1.1% | Added |
| TD Asset Management Inc | 126,837 | $6.40M | 0.01% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 127,500 | $6.43M | 0.53% | +62,500+96.2% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 132,054 | $6.66M | 0.04% | +102,269+343.4% | Added |
| Alliancebernstein L.P. | 154,660 | $7.80M | 0.00% | −700−0.5% | Reduced |
| New York State Common Retirement Fund | 156,893 | $7.92M | 0.01% | −23,368−13.0% | Reduced |
| Wells Fargo & Company | 164,745 | $8.31M | 0.00% | +16,972+11.5% | Added |
| Teachers Retirement System of the State of Kentucky | 171,496 | $8.65M | 0.08% | −3,300−1.9% | Reduced |
| Swiss National Bank | 174,100 | $8.78M | 0.01% | +2,300+1.3% | Added |
| Wasatch Advisors Inc | 174,528 | $8.80M | 0.04% | −362,718−67.5% | Reduced |
| Prudential Financial Inc | 187,462 | $9.46M | 0.01% | −32,552−14.8% | Reduced |
| California Public Employees Retirement System | 201,374 | $10.2M | 0.01% | +2,713+1.4% | Added |
| AXA S.A. | 201,580 | $10.2M | 0.03% | +18,880+10.3% | Added |
| Tekla Capital Management LLC | 222,420 | $11.2M | 0.36% | +72,334+48.2% | Added |
| Jennison Associates LLC | 228,422 | $11.5M | 0.01% | −146,090−39.0% | Reduced |
| Marshall Wace North America L.P. | 231,977 | $11.7M | 0.05% | +219,062+1,696.2% | Added |
| Eagle Asset Management Inc | 242,545 | $12.2M | 0.06% | −48,558−16.7% | Reduced |
| Natixis | 279,254 | $14.1M | 0.05% | +69,556+33.2% | Added |
| Principal Financial Group Inc | 303,827 | $15.3M | 0.01% | −25,517−7.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 338,730 | $17.1M | 0.04% | −6,570−1.9% | Reduced |
| Federated Hermes, Inc. | 339,160 | $17.1M | 0.03% | +200,528+144.6% | Added |
| American Century Companies Inc | 348,987 | $17.6M | 0.01% | +56,140+19.2% | Added |
| Bank of New York Mellon Corp | 376,719 | $19.0M | 0.00% | +29,350+8.4% | Added |
| Nuveen Asset Management, LLC | 365,078 | $19.3M | 0.01% | −18,982−4.9% | Reduced |
| Morgan Stanley | 383,993 | $19.4M | 0.00% | −47,039−10.9% | Reduced |
| Hamilton Lane Advisors LLC | 396,944 | $20.0M | 3.36% | +396,944 | New |
| Two Sigma Advisers, LP | 421,100 | $21.2M | 0.06% | −43,000−9.3% | Reduced |
| UBS Asset Management Americas Inc | 434,734 | $21.9M | 0.01% | +4,863+1.1% | Added |
| Artal Group S.A. | 500,000 | $25.2M | 0.62% | 00.0% | Unchanged |
| Marshall Wace, LLP | 531,358 | $26.8M | 0.13% | −114,641−17.7% | Reduced |
| Artisan Partners Limited Partnership | 550,987 | $27.8M | 0.03% | −15,858−2.8% | Reduced |
| Dimensional Fund Advisors LP | 634,735 | $32.0M | 0.01% | +309,387+95.1% | Added |
| Charles Schwab Investment Management Inc | 703,752 | $35.5M | 0.01% | +63,518+9.9% | Added |
| Norges Bank | 853,356 | $43.1M | 0.01% | +111,376+15.0% | Added |
| Pictet Asset Management SA | 868,503 | $43.8M | 0.05% | +868,503 | New |
| Northern Trust Corp | 951,725 | $48.0M | 0.01% | −27,333−2.8% | Reduced |
| Pathway Capital Management, LP | 1,012,240 | $51.1M | 24.47% | +1,012,240 | New |
| Goldman Sachs Group Inc | 1,056,558 | $53.3M | 0.01% | +468,740+79.7% | Added |