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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
210
−7 vs. Q1 2021
Shares held
80.6M
+149.8K (+0.2%) vs. Q1 2021
Total value
$6.32B
+$1.72B (+37.5%) vs. Q1 2021
New holders
34
81 more added
Sold out
41
59 more reduced

1 institution that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 210 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2021: $6.32B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2021.

Institutions holding DNLI in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
State Street Corp2,320,460$182.0M0.01%+303,793+15.1%Added
FMR LLC2,669,083$209.4M0.02%−18,617−0.7%Reduced
Flagship Pioneering Inc.2,730,263$214.2M2.74%00.0%Unchanged
Gilder Gagnon Howe & Co LLC2,835,733$222.4M1.09%−168,820−5.6%Reduced
Temasek Holdings (Private) Ltd4,410,457$346.0M1.16%00.0%Unchanged
Price T Rowe Associates Inc4,903,452$384.6M0.04%−1,154,827−19.1%Reduced
BlackRock Inc.7,036,041$551.9M0.02%+471,589+7.2%Added
Vanguard Group Inc7,644,130$599.6M0.01%−522,320−6.4%Reduced
Crestline Management, LP8,135,481$638.1M55.19%−1,849,355−18.5%Reduced
Baillie Gifford & Co15,147,613$1.19B0.58%+2,152,416+16.6%Added
IFP Advisors, Inc0$00.00%−20−100.0%Sold out
Citadel Advisors LLC0$00.00%−240,784−100.0%Sold out
Caas Capital Management LP0$00.00%−232,796−100.0%Sold out
Hamilton Lane Advisors LLC0$00.00%−97,370−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−85,607−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−39,106−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−27,958−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−26,777−100.0%Sold out
University of Texas/Texas Am Investment Managment Co0$00.00%−23,629−100.0%Sold out
Mackay Shields LLC0$00.00%−22,400−100.0%Sold out
Jefferies Group LLC0$00.00%−21,100−100.0%Sold out
Duality Advisers, LP0$00.00%−19,642−100.0%Sold out
Fred Alger Management, LLC0$00.00%−16,634−100.0%Sold out
Trexquant Investment LP0$00.00%−16,192−100.0%Sold out
Jump Financial, LLC0$00.00%−14,300−100.0%Sold out
AlphaCrest Capital Management LLC0$00.00%−13,400−100.0%Sold out
Ergoteles LLC0$00.00%−10,300−100.0%Sold out
Frontier Capital Management Co LLC0$00.00%−7,742−100.0%Sold out
Athanor Capital, LP0$00.00%−6,709−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−6,570−100.0%Sold out
Tao Capital Management LP0$00.00%−6,086−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−5,583−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−4,886−100.0%Sold out
XTX Topco Ltd0$00.00%−3,683−100.0%Sold out
FORA Capital, LLC0$00.00%−2,020−100.0%Sold out
Bank of Montreal0$00.00%−1,885−100.0%Sold out
Pacer Advisors, Inc.0$00.00%−1,204−100.0%Sold out
HM Payson & Co0$00.00%−1,013−100.0%Sold out
Walleye Trading LLC0$00.00%−835−100.0%Sold out
Lazard Asset Management LLC0$00.00%−833−100.0%Sold out
Cutler Group LP0$00.00%−600−100.0%Sold out
Bank Julius Baer & Co. Ltd, Zurich0$00.00%−500−100.0%Sold out
Simplex Trading, LLC0$00.00%−449−100.0%Sold out
Ameritas Investment Company, LLC0$00.00%−200−100.0%Sold out
Sowell Financial Services LLC0$00.00%−160−100.0%Sold out
Exchange Traded Concepts, LLC0$00.00%−125−100.0%Sold out
Signaturefd, LLC0$00.00%−67−100.0%Sold out
Alpha DNA Investment Management LLC0$00.00%−79−100.0%Sold out
Lindbrook Capital, LLC0$00.00%−34−100.0%Sold out
Parallel Advisors, LLC0$00.00%−12−100.0%Sold out
Raffa Wealth Management, LLC0$00.00%−1−100.0%Sold out
Amundi Asset Management US, Inc.––––Not filed